keyword
MENU ▼
Read by QxMD icon Read
search

Mucorales

keyword
https://www.readbyqxmd.com/read/27918580/correction-gene-expansion-shapes-genome-architecture-in-the-human-pathogen-lichtheimia-corymbifera-an-evolutionary-genomics-analysis-in-the-ancient-terrestrial-mucorales-mucoromycotina
#1
Volker U Schwartze, Sascha Winter, Ekaterina Shelest, Marina Marcet-Houben, Fabian Horn, Stefanie Wehner, Jörg Linde, Vito Valiante, Michael Sammeth, Konstantin Riege, Minou Nowrousian, Kerstin Kaerger, Ilse D Jacobsen, Manja Marz, Axel A Brakhage, Toni Gabaldón, Sebastian Böcker, Kerstin Voigt
[This corrects the article DOI: 10.1371/journal.pgen.1004496.].
December 2016: PLoS Genetics
https://www.readbyqxmd.com/read/27905900/prevalence-clinical-and-economic-burden-of-mucormycosis-related-hospitalizations-in-the-united-states-a-retrospective-study
#2
Dimitrios P Kontoyiannis, Hongbo Yang, Jinlin Song, Sneha S Kelkar, Xi Yang, Nkechi Azie, Rachel Harrington, Alan Fan, Edward Lee, James R Spalding
BACKGROUND: Mucormycosis is a rare but devastating fungal infection primarily affecting immunocompromised patients such as those with hematological malignancy, bone marrow and solid organ transplantation, and patients with diabetes, and, even more rarely, immunocompetent patients. The objective of this study was to assess the prevalence and burden, both clinical and economic, of mucormycosis among hospitalized patients in the U.S. METHODS: This is a retrospective study using the Premier Perspective(TM) Comparative Database, with more than 560 participating hospitals covering 104 million patients (January 2005-June 2014)...
December 1, 2016: BMC Infectious Diseases
https://www.readbyqxmd.com/read/27904061/diagnosis-and-treatment-of-mucormycosis-in-patients-with-hematological-malignancies
#3
Yuki Asano-Mori
The risk of invasive fungal infections (IFIs) is extremely high in patients with hematological malignancies due to the prolonged and profound neutropenia and immunosuppression after chemotherapy and hematopoietic stem cell transplantation. There has been increasing interest in mucormycosis despite its relatively uncommon occurrence, because occasional breakthrough infections have been observed under anti-aspergillus prophylaxis. The aggressive nature of mucormycosis easily leads to high mortality because of delays in diagnosis and incorrect treatment decisions, which are due in part to lack of adjunctive diagnostic tools and having similar clinical and radiological features with aspergillosis...
2016: Medical Mycology Journal
https://www.readbyqxmd.com/read/27902424/clinical-evaluation-of-mucorales-specific-real-time-pcr-assay-in-tissue-and-serum-samples
#4
Jan Springer, Michaela Lackner, Christian Ensinger, Brigitte Risslegger, Charles Oliver Morton, David Nachbaur, Cornelia Lass-Flörl, Hermann Einsele, Werner J Heinz, Juergen Loeffler
Molecular diagnostic assays can accelerate the diagnosis of fungal infections and subsequently improve patient outcomes. In particular, the detection of infections due to Mucorales is still challenging for laboratories and physicians. The aim of this study was to evaluate a probe-based Mucorales-specific real-time PCR assay (Muc18S) using tissue and serum samples from patients suffering from invasive mucormycosis (IMM). This assay can detect a broad range of clinically relevant Mucorales species and can be used to complement existing diagnostic tests or to screen high-risk patients...
October 24, 2016: Journal of Medical Microbiology
https://www.readbyqxmd.com/read/27880667/the-current-treatment-landscape-other-fungal-diseases-cryptococcosis-fusariosis-and-mucormycosis
#5
Olivier Lortholary, Mario Fernández-Ruiz, John R Perfect
Compared with major invasive mycoses such as aspergillosis and candidiasis, the antifungal stewardship management strategies of other fungal diseases have different opportunities and considerations. Cryptococcosis, fusariosis and mucormycosis are globally prevalent invasive fungal diseases (IFDs), but are not currently included in antifungal prophylaxis guidelines for immunocompromised hosts. Since the implementation of biomarkers as part of diagnostic screening strategies, the concept of pre-emptive antifungal therapy has emerged for these IFDs...
November 2016: Journal of Antimicrobial Chemotherapy
https://www.readbyqxmd.com/read/27875508/extensive-oral-mucormycosis-in-a-transplanted-patient
#6
Bernar Monteiro Benites, Felipe Paiva Fonseca, Claudia Joffily Parahyba, Sergio Samir Arap, Yana Augusta Novis, Eduardo Rodrigues Fregnani
Mucormycosis is an invasive fungal disease caused by fungi from the Mucorales order that are found in the soil and decaying organic debris. Mucormycosis has been reported to be the third most common fungal disease in stem cell transplanted patients. The fungi have a tendency for vascular invasion, resulting in thrombi development, which decreases blood supply and leads to extensive tissue necrosis. Here, the authors present a patient of mucormycosis affecting the soft palate, oropharynx, and hypopharynx in a type II diabetic male patient who underwent allogeneic stem cell transplantation, and the authors further review the literature on oral mucormycosis for the last 10 years...
November 21, 2016: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/27845850/ct-guided-percutaneous-lung-biopsies-in-patients-with-suspicion-for-infection-may-yield-clinically-useful-information
#7
Brian M Haas, Joshua D Clayton, Brett M Elicker, Karen G Ordovas, David M Naeger
OBJECTIVE: The objective of our study was to assess the frequency and time frame with which CT-guided lung biopsies for suspected infection yield information that can affect patient management. MATERIALS AND METHODS: All CT-guided lung biopsies over a 68-month period performed for the purpose of diagnosing a suspected infection were reviewed to determine the proportion that yielded information affecting patient management. Patients were included if infection was the only consideration causing the pulmonary lesion in question...
November 15, 2016: AJR. American Journal of Roentgenology
https://www.readbyqxmd.com/read/27807151/identification-of-molds-by-maldi-tof-mass-spectrometry
#8
Maurizio Sanguinetti, Brunella Posteraro
Despite to lesser extent than the diagnostic bacteriology, MALDI-TOF MS has recently revolutionized the diagnostic mycology workflow. With regards to filamentous fungi (or molds), the precise recognition of pathogenic species is important for rapid diagnosis and appropriate treatment, especially in invasive diseases. This review summarizes the current experience with MALDI-TOF MS-based identification of common and uncommon mold species, belonging to Aspergillus, Fusarium, Mucorales, dimorphic fungi, and dermatophytes...
November 2, 2016: Journal of Clinical Microbiology
https://www.readbyqxmd.com/read/27798213/monotherapy-or-combination-therapy-of-isavuconazole-and-micafungin-for-treating-murine-mucormycosis
#9
Teclegiorgis Gebremariam, Nathan P Wiederhold, Abdullah Alqarihi, Priya Uppuluri, Nkechi Azie, John E Edwards, Ashraf S Ibrahim
OBJECTIVES: Previously we demonstrated the benefit of isavuconazole in treating murine mucormycosis due to Rhizopus. We wanted to determine the efficacy of isavuconazole in treating murine mucormycosis caused by Mucor, the second most common cause of the disease. Furthermore, because we previously determined that Rhizopus possesses the target enzyme for echinocandins and micafungin has activity against murine mucormycosis, we compared the activity of combination therapy (isavuconazole + micafungin) with placebo, either drug alone or standard therapy of liposomal amphotericin B (LAmB) in treating pulmonary murine mucormycosis caused by Rhizopus delemar...
October 24, 2016: Journal of Antimicrobial Chemotherapy
https://www.readbyqxmd.com/read/27769884/coprophilous-mucorales-ex-zygomycota-from-three-areas-in-the-semi-arid-of-pernambuco-brazil
#10
Carlos Alberto Fragoso de Souza, Diogo Xavier Lima, Luciana M S Gurgel, André Luiz Cabral Monteiro de Azevedo Santiago
Mucorales comprises fungi commonly isolated as saprobes from soil, dung, stored grains and plants. Although these fungi have been studied in several countries, there are relatively a few reports of them in semi-arid areas. Therefore, the aims of the present study were to assess and compare the Mucorales communities in dung from different species and breeds of herbivores in the semi-arid of Pernambuco, based on the frequency of occurrence and species richness of these fungi. Samples of dung collected in the cities of Arcoverde, Serra Talhada and Sertânia were incubated in moist chambers in triplicate...
October 4, 2016: Brazilian Journal of Microbiology: [publication of the Brazilian Society for Microbiology]
https://www.readbyqxmd.com/read/27707801/mitochondrial-carriers-link-the-catabolism-of-hydroxyaromatic-compounds-to-the-central-metabolism-in-candida-parapsilosis
#11
Igor Zeman, Martina Neboháčová, Gabriela Gérecová, Kornélia Katonová, Eva Jánošiková, Michaela Jakúbková, Ivana Centárová, Ivana Dunčková, Ĺubomir Tomáška, Leszek P Pryszcz, Toni Gabaldón, Jozef Nosek
The pathogenic yeast Candida parapsilosis metabolizes hydroxyderivatives of benzene and benzoic acid to compounds channeled into central metabolism including the mitochondrially-localized tricarboxylic acid cycle via the 3-oxoadipate and gentisate pathways. The orchestration of both catabolic pathways with mitochondrial metabolism as well as their evolutionary origin is not fully understood. Our results show that the enzymes involved in these two pathways operate in the cytoplasm with the exception of the mitochondrially-targeted 3-oxoadipate CoA-transferase (Osc1p) and 3-oxoadipyl-CoA thiolase (Oct1p) catalyzing the last two reactions of the 3-oxoadipate pathway...
October 5, 2016: G3: Genes—Genomes—Genetics
https://www.readbyqxmd.com/read/27704055/percutaneous-management-of-systemic-fungal-infection-presenting-as-bilateral-renal-fungal-ball
#12
Abhishek Shukla, Nitin Shrivastava, Chirom Amit Singh, Brusabhanu Nayak
Background: Zygomycoses are uncommon, frequently fatal diseases caused by fungi of the class Zygomycetes. The majority of human cases are caused by Mucorales (genus-rhizopus, mucor, and absidia) fungi. Renal involvement is uncommon and urine microscopy, pottasium hydroxide mount, and fungal cultures are frequently negative. Case Presentation: A twenty-one-year-old young unmarried lady presented to our emergency department with bilateral flank pain, fever, nausea, and decreased urine output of one-month duration...
2016: Journal of Endourology Case Reports
https://www.readbyqxmd.com/read/27697173/effect-of-bioaugmented-inoculation-on-microbiota-dynamics-during-solid-state-fermentation-of-daqu-starter-using-autochthonous-of-bacillus-pediococcus-wickerhamomyces-and-saccharomycopsis
#13
Pan Li, Weifeng Lin, Xiong Liu, Xiaowen Wang, Xing Gan, Lixin Luo, Wei-Tie Lin
Daqu, a traditional fermentation starter that is used for Chinese liquor and vinegar production, is still manufactured through a traditional spontaneous solid-state fermentation process with no selected microorganisms are intentionally inoculated. The aim of this work was to analyze the microbiota dynamics during the solid-state fermentation process of Daqu using a traditional and bioaugmented inoculation with autochthonous of Bacillus, Pediococcus, Saccharomycopsis and Wickerhamomyces at an industrial scale...
February 2017: Food Microbiology
https://www.readbyqxmd.com/read/27562696/antifungal-susceptibilities-of-non-aspergillus-filamentous-fungi-causing-invasive-infection-in-australia-support-for-current-antifungal-guideline-recommendations
#14
Catriona L Halliday, Sharon C-A Chen, Sarah E Kidd, Sebastian van Hal, Belinda Chapman, Christopher H Heath, Andie Lee, Karina J Kennedy, Kathryn Daveson, Tania C Sorrell, C Orla Morrissey, Deborah J Marriott, Monica A Slavin
Antifungal susceptibilities of non-Aspergillus filamentous fungal pathogens cannot always be inferred from their identification. Here we determined, using the Sensititre(®) YeastOne(®) YO10 panel, the in vitro activities of nine antifungal agents against 52 clinical isolates of emergent non-Aspergillus moulds representing 17 fungal groups in Australia. Isolates comprised Mucorales (n = 14), Scedosporium/Lomentospora spp. (n = 18) and a range of hyaline hyphomycetes (n = 9) and other dematiaceous fungi (n = 11)...
October 2016: International Journal of Antimicrobial Agents
https://www.readbyqxmd.com/read/27554217/-gastric-mucormycosis-followed-by-traumatic-cardiac-rupture-in-an-immunocompetent-patient
#15
Sang Won Lee, Hyun Seok Lee
Gastric mucormycosis is a rare and life-threatening fungal disease, caused by fungus in the order Mucorales. While rhino-cerebral and pulmonary forms are common, gastric mucormycosis is an uncommon site for the disease. We diagnosed gastric mucormycosis in a 41-year-old female who had severe multiple trauma, including cardiac rupture, due to a traffic accident. Eighteen days after hospitalization, she passed 800 mL of melena over one day. We performed upper esophagogastroduodenoscopy (EGD) and found a huge gastric ulcer with bleeding...
August 25, 2016: Korean Journal of Gastroenterology, Taehan Sohwagi Hakhoe Chi
https://www.readbyqxmd.com/read/27554148/metagenomic-analysis-of-fungal-diversity-in-korean-traditional-wheat-based-fermentation-starter-nuruk
#16
Jyotiranjan Bal, Suk-Hyun Yun, Soo-Hwan Yeo, Jung-Mi Kim, Dae-Hyuk Kim
Nuruk, a traditional natural starter, is extensively used in the brewing of Makgeolli, one of Korea's most popular alcoholic beverages that has been recently gaining global popularity. Thus, the quality of traditional nuruk needs to be enhanced. The nuruk mycobiome greatly influences both fermentation process as well as palatability enhancement. Limitations of culture-dependent identification restrict an accurate analysis of fungal diversity and distribution in nuruks. 454 pyrosequencing of two traditional wheat-based nuruks, prepared at two representative temperature conditions revealed a total of 153 and 53 OTUs for nuruks A and B, respectively, from a total of 33,157 ITS sequences...
December 2016: Food Microbiology
https://www.readbyqxmd.com/read/27543818/mould-and-mycotoxin-exposure-assessment-of-melon-and-bush-mango-seeds-two-common-soup-thickeners-consumed-in-nigeria
#17
Chibundu N Ezekiel, Michael Sulyok, Yinka Somorin, Foluke I Odutayo, Stella U Nwabekee, Afeez T Balogun, Rudolf Krska
An examination of the mould and fungal metabolite pattern in melon and bush mango seeds locally produced in Nigeria was undertaken in order to understand the mycotoxicological risk posed to consumers of both of these important and commonly consumed soup thickeners. The variation in mycotoxin levels in graded categories of both foodstuffs were also determined. Aspergillus, Fusarium, Penicillium, Mucorales and Trichoderma were the recovered fungi from the foodstuffs with Aspergillus species dominating (melon=97...
November 21, 2016: International Journal of Food Microbiology
https://www.readbyqxmd.com/read/27540378/environmental-factors-affecting-microbiota-dynamics-during-traditional-solid-state-fermentation-of-chinese-daqu-starter
#18
Pan Li, Weifeng Lin, Xiong Liu, Xiaowen Wang, Lixin Luo
In this study, we investigated the microbiota dynamics during two industrial-scale traditional solid-state fermentation (SSF) processes of Daqu starters. Similar evolution profiles of environmental parameters, enzymatic activities, microbial amounts, and communities were observed during the medium temperature SSF (MTSSF) and low temperature SSF (LTSSF) processes. Orders of Rickettsiales and Streptophyta only dominated the initial 2 days, and Eurotiales only predominated from days 10 to 24, however, phylotypes of Enterobacteriales, Lactobacillales, Bacillales, Saccharomycetales, and Mucorales both prevailed throughout the MTSSF and LTSSF processes...
2016: Frontiers in Microbiology
https://www.readbyqxmd.com/read/27535951/detection-of-circulating-mucorales-dna-in-critically-ill-burn-patients-preliminary-report-of-a-screening-strategy-for-early-diagnosis-and-treatment
#19
Matthieu Legrand, Maud Gits-Muselli, Louis Boutin, Dea Garcia-Hermoso, Véronique Maurel, Sabri Soussi, Mourad Benyamina, Axelle Ferry, Maïté Chaussard, Samia Hamane, Blandine Denis, Sophie Touratier, Nicolas Guigue, Emilie Fréalle, Mathieu Jeanne, Jean-Vivien Shaal, Charles Soler, Maurice Mimoun, Marc Chaouat, Matthieu Lafaurie, Alexandre Mebazaa, Stéphane Bretagne, Alexandre Alanio
BACKGROUND:  Invasive wound mucormycosis (IWM) is associated with an extremely poor outcome among critically ill burn patients. The purpose of this study was to describe the detection of circulating Mucorales DNA for the early recognition of IWM in critically ill burn patients and to report the potential value of detecting circulating Mucorales DNA (cmDNA) for treatment guidance. METHODS:  Severely ill burn patients admitted to a tertiary referral center between October 2013 and February 2016 were included...
August 17, 2016: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
https://www.readbyqxmd.com/read/27475007/-sinonasal-fungal-infections-are-not-exclusively-due-to-mucorales-and-aspergillus
#20
Arnault Tauziède-Espariat, Michel Wassef, Homa Adle-Biassette, Alexandre Alanio, Stéphane Bretagne, Fanny Lanternier, Mohammed Boui, Olivier Bouchaud, Pierre Vironneau, Romain Kania, Grégory Jouvion, Fabrice Chrétien, Marion Classe
Rhino-sinusal infections are serious diseases and possibly lethal. When they are invasive, we easily discuss apergilloses and mucormycoses. The confirmation of the diagnosis of mucormycosis need an extensive surgery for precise histopathological and mycological evaluation. The pathologist may be faced to other rare mycoses such as phaeohyphomycoses, which present different morphological features than mucormycoses and Aspergillus. Once the diagnosis is established, an appropriate antifungal treatment is quickly started...
August 2016: Annales de Pathologie
keyword
keyword
23216
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"