Satish K Raut, Kulwinder Singh, Shridhar Sanghvi, Veronica Loyo-Celis, Liyah Varghese, Ekam R Singh, Shubha Gururaja Rao, Harpreet Singh
Chloride is a key anion involved in cellular physiology by regulating its homeostasis and rheostatic processes. Changes in cellular Cl- concentration result in differential regulation of cellular functions such as transcription and translation, post-translation modifications, cell cycle and proliferation, cell volume, and pH levels. In intracellular compartments, Cl- modulates the function of lysosomes, mitochondria, endosomes, phagosomes, the nucleus, and the endoplasmic reticulum. In extracellular fluid (ECF), Cl- is present in blood/plasma, and interstitial fluid compartments...
April 4, 2024: Bioscience Reports