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Childhood Development

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https://www.readbyqxmd.com/read/28101905/mapping-the-road-from-childhood-adversity-to-personality-disorder-the-role-of-unresolved-states-of-mind
#1
Antonella Cirasola, Saul Hillman, Peter Fonagy, Marco Chiesa
Childhood adversity has been found to be an important aetiological factor in the development of personality disorder (PD) in several studies. However, the role of disorganized attachment with unresolved mental states for traumatic experiences requires further investigation. This study explores the relationship between childhood adversities, unresolved states of mind, PD diagnosis and psychiatric distress. Two hundred forty-five adult participants, 124 from a clinical PD group and 121 non-psychiatric controls were assessed using the Structured Clinical Interview for DSM-IV, the Cassel Baseline Questionnaire, the Symptom Checklist-90-R and the Adult Attachment Interview, in order to ascertain presence of PD, childhood adversity, level of psychiatric distress and unresolved states of mind...
January 19, 2017: Personality and Mental Health
https://www.readbyqxmd.com/read/28101803/lung-retransplantation-in-an-adult-13%C3%A2-years-after-single-lobar-transplant-in-childhood
#2
Seiichiro Sugimoto, Shinji Otani, Takashi Ohki, Takeshi Kurosaki, Kentaroh Miyoshi, Masaomi Yamane, Shinichiro Miyoshi, Takahiro Oto
Single living-donor lobar lung transplantation provides acceptable results for critically ill children; however, an additional lung transplantation may be required in the future as the recipient grows. We describe a case of successful lung retransplantation in a grown-up patient after single lobar lung transplantation in childhood. A 23-year-old man underwent bilateral cadaveric lung retransplantation for chronic lung allograft dysfunction 13 years after right single living-donor lobar transplantation for idiopathic pulmonary arterial hypertension performed at the age of 10 years...
January 18, 2017: General Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/28101776/plyometric-exercise-and-bone-health-in-children-and-adolescents-a-systematic-review
#3
REVIEW
Alejandro Gómez-Bruton, Ángel Matute-Llorente, Alejandro González-Agüero, José A Casajús, Germán Vicente-Rodríguez
BACKGROUND: Many jumping interventions have been performed in children and adolescents in order to improve bone-related variables and thus, ensure a healthy bone development during these periods and later in life. This systematic review aims to summarize and update present knowledge regarding the effects that jumping interventions may have on bone mass, structure and metabolism in order to ascertain the efficacy and durability (duration of the effects caused by the intervention) of the interventions...
January 19, 2017: World Journal of Pediatrics: WJP
https://www.readbyqxmd.com/read/28101530/integrative-analysis-of-disease-signatures-shows-inflammation-disrupts-juvenile-experience-dependent-cortical-plasticity
#4
Milo R Smith, Poromendro Burman, Masato Sadahiro, Brian A Kidd, Joel T Dudley, Hirofumi Morishita
Throughout childhood and adolescence, periods of heightened neuroplasticity are critical for the development of healthy brain function and behavior. Given the high prevalence of neurodevelopmental disorders, such as autism, identifying disruptors of developmental plasticity represents an essential step for developing strategies for prevention and intervention. Applying a novel computational approach that systematically assessed connections between 436 transcriptional signatures of disease and multiple signatures of neuroplasticity, we identified inflammation as a common pathological process central to a diverse set of diseases predicted to dysregulate plasticity signatures...
November 2016: ENeuro
https://www.readbyqxmd.com/read/28100454/gene-therapy-targeting-oligodendrocytes-provides-therapeutic-benefit-in-a-leukodystrophy-model
#5
Elena Georgiou, Kyriaki Sidiropoulou, Jan Richter, Christos Papaneophytou, Irene Sargiannidou, Alexia Kagiava, Georg von Jonquieres, Christina Christodoulou, Matthias Klugmann, Kleopas A Kleopa
Pelizaeus-Merzbacher-like disease or hypomyelinating leukodystrophy-2 is an autosomal recessively inherited leukodystrophy with childhood onset resulting from mutations in the gene encoding the gap junction protein connexin 47 (Cx47, encoded by GJC2). Cx47 is expressed specifically in oligodendrocytes and is crucial for gap junctional communication throughout the central nervous system. Previous studies confirmed that a cell autonomous loss-of-function mechanism underlies hypomyelinating leukodystrophy-2 and that transgenic oligodendrocyte-specific expression of another connexin, Cx32 (GJB1), can restore gap junctions in oligodendrocytes to achieve correction of the pathology in a disease model...
January 18, 2017: Brain: a Journal of Neurology
https://www.readbyqxmd.com/read/28100146/examining-the-relationship-between-childhood-victimization-high-risk-behaviors-and-health-among-criminal-justice-involved-women
#6
Tanya Renn, Seana Golder, George Higgins, T K Logan, Katherine M Winham
The purpose of this study was to develop and test a conceptual model of the pathways through which childhood victimization influences adult health outcomes. Specifically, measures of high-risk behaviors, tobacco use, alcohol use, illegal substance use, and HIV risk behaviors were hypothesized to mediate the relationship between childhood victimization and adult physical health. The sample consisted of 406 women on probation and parole with a history of childhood victimization in Jefferson County, Kentucky. Structural equation modeling was used to examine the relationship between childhood victimization, high-risk behaviors, and physical health outcomes...
January 2017: Journal of Correctional Health Care
https://www.readbyqxmd.com/read/28099628/elevated-plasma-concentrations-of-s100-calcium-binding-protein-b-and-tumor-necrosis-factor-alpha-in-children-with-autism-spectrum-disorders
#7
Selin Aktan Guloksuz, Osman Abali, Esin Aktas Cetin, Sema Bilgic Gazioglu, Gunnur Deniz, Abdurrahman Yildirim, Ivana Kawikova, Sinan Guloksuz, James F Leckman
Objective: To investigate plasma concentrations of S100B (a calcium-binding protein derived primarily from the glia) and inflammatory cytokines in children with autism and the relationship between S100B and cytokine concentrations. Methods: Plasma levels of S100B, tumor necrosis factor alpha (TNF-α), interferon gamma, interleukin (IL)-1β, IL-4, IL-6, IL-10, and IL-17A were measured in 40 unmedicated children with autism and 35 normally developing healthy children...
January 12, 2017: Revista Brasileira de Psiquiatria
https://www.readbyqxmd.com/read/28098769/sensory-acceptability-of-infant-cereals-with-whole-grain-in-infants-and-young-children
#8
Juan Francisco Haro-Vicente, Maria Jose Bernal-Cava, Amparo Lopez-Fernandez, Gaspar Ros-Berruezo, Stefan Bodenstab, Luis Manuel Sanchez-Siles
In many countries, infant cereals are one of the first foods introduced during the complementary feeding stage. These cereals are usually made with refined cereal flours, even though several health benefits have been linked to the intake of whole grain cereals. Prior evidence suggests that food preferences are developed at early stages of life, and may persist in later childhood and adulthood. Our aim was to test whether an infant cereal with 30% of whole grain was similarly accepted both by parents and infants in comparison to a similar cereal made from refined flour...
January 13, 2017: Nutrients
https://www.readbyqxmd.com/read/28098505/facilitating-and-hindering-factors-for-coping-with-the-experience-of-having-a-child-with-cancer-a-lebanese-perspective
#9
Myrna A A Doumit, May Naifeh Khoury
BACKGROUND: Families with a child with cancer face significant emotional and psychosocial stressors. The frequency of childhood cancer is increasing in Lebanon with more than 282 children diagnosed each year. This condition is reported to evoke a range of challenging emotions for parents, yet no studies have been conducted on the facilitating and hindering factors that affect Lebanese parents coping with a child with cancer. OBJECTIVES: The purpose of the study was to gain an in-depth understanding of factors facilitating and hindering coping methods of Lebanese parents with a child with cancer...
January 18, 2017: Journal of Psychosocial Oncology
https://www.readbyqxmd.com/read/28097673/schoolyard-shade-and-sun-exposure-assessment-of-personal-monitoring-during-children-s-physical-activity
#10
Jennifer K Vanos, Grant R McKercher, Kylie Naughton, Marc Lochbaum
Childhood exposure to ultraviolet radiation (UVR) is a major risk factor for the development of melanoma later in life. However, it is challenging to accurately determine personal outdoor exposure to UVR, specifically erythemally-weighted UVR (UVEry ), due to technological constraints, variable time-activity patterns, and the influence of outdoor environmental design. To address this challenge, the current study utilized mobile and stationary techniques to examine the UVEry exposures of 14 children in a schoolyard in Lubbock, TX in spring 2016...
January 18, 2017: Photochemistry and Photobiology
https://www.readbyqxmd.com/read/28097617/rates-and-covariates-of-recent-sexual-and-physical-violence-against-hiv-infected-outpatient-drinkers-in-western-kenya
#11
Rebecca K Papas, Benson N Gakinya, Michael M Mwaniki, Hana Lee, Stella W Kiarie, Steve Martino, Michelle P Loxley, Alfred K Keter, Debra A Klein, John E Sidle, Joyce B Baliddawa, Stephen A Maisto
Victimization from physical and sexual violence presents global health challenges. Partner violence is higher in Kenya than Africa. Violence against drinkers and HIV-infected individuals is typically elevated, so dual vulnerabilities may further augment risk. Understanding violence risks can improve interventions. Participants were 614 HIV-infected outpatient drinkers in western Kenya enrolled in a randomized trial to reduce alcohol use. At baseline, past 90-day partner physical and sexual violence were examined descriptively and in gender-stratified regression models...
January 17, 2017: AIDS and Behavior
https://www.readbyqxmd.com/read/28097446/temperament-traits-and-psychopathology-in-young-clinically-referred-children-compared-to-a-general-population-sample
#12
Frederike Y Scheper, Mirjana Majdandžić, Peter M van de Ven, Lucres M C Jansen, Theo A H Doreleijers, Carlo Schuengel, Annelou L C de Vries
Evidence from general population studies shows the contribution of various temperament traits to the development of child psychopathology. Little is known about which traits are associated with internalizing and externalizing problems in young clinically referred children. The current study assessed temperament and internalizing and externalizing problems in 216 referred children (M = 4.35 years, SD 0.89, 81% boys). A comparison was made with an age and gender matched general population sample. Referred children showed less effortful control than general population children...
January 18, 2017: Child Psychiatry and Human Development
https://www.readbyqxmd.com/read/28095869/macrophage-activation-syndrome-different-mechanisms-leading-to-a-one-clinical-syndrome
#13
REVIEW
Claudia Bracaglia, Giusi Prencipe, Fabrizio De Benedetti
BACKGROUND: Macrophage activation syndrome (MAS) is a severe complication of rheumatic disease in childhood, particularly in systemic Juvenile Idiopathic Arthritis (sJIA). It is characterize by an uncontrolled activation and proliferation of T lymphocytes and macrophages. MAIN CONTENT: MAS is currently classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH). The reason is that MAS shares clinical and laboratory features with primary genetic HLH (pHLH)...
January 17, 2017: Pediatric Rheumatology Online Journal
https://www.readbyqxmd.com/read/28095826/non-invasive-respiratory-support-for-infants-with-bronchiolitis-a-national-survey-of-practice
#14
H Turnham, R S Agbeko, J Furness, J Pappachan, A G Sutcliffe, P Ramnarayan
BACKGROUND: Bronchiolitis is a common respiratory illness of early childhood. For most children it is a mild self-limiting disease but a small number of children develop respiratory failure. Nasal continuous positive airway pressure (nCPAP) has traditionally been used to provide non-invasive respiratory support in these children, but there is little clinical trial evidence to support its use. More recently, high-flow nasal cannula therapy (HFNC) has emerged as a novel respiratory support modality...
January 17, 2017: BMC Pediatrics
https://www.readbyqxmd.com/read/28095738/emotional-intelligence-as-an-evolutive-factor-on-adult-with-adhd
#15
Javier Quintero, Rosa Vera, Isabel Morales, Pilar Zuluaga, Alberto Fernández
OBJECTIVE: ADHD adults exhibit deficits in emotion recognition, regulation, and expression. Emotional intelligence (EI) correlates with better life performance and is considered a skill that can be learned and developed. The aim of this study was to assess EI development as ability in ADHD adults, considering the effect of comorbid psychiatric disorders and previous diagnosis of ADHD. METHOD: Participants ( n = 116) were distributed in four groups attending to current comorbidities and previous ADHD diagnosis, and administered the Mayer-Salovey-Caruso Emotional Intelligence Test version 2...
January 1, 2017: Journal of Attention Disorders
https://www.readbyqxmd.com/read/28095505/can-early-intervention-improve-maternal-well-being-evidence-from-a-randomized-controlled-trial
#16
Orla Doyle, Liam Delaney, Christine O'Farrelly, Nick Fitzpatrick, Michael Daly
OBJECTIVE: This study estimates the effect of a targeted early childhood intervention program on global and experienced measures of maternal well-being utilizing a randomized controlled trial design. The primary aim of the intervention is to improve children's school readiness skills by working directly with parents to improve their knowledge of child development and parenting behavior. One potential externality of the program is well-being benefits for parents given its direct focus on improving parental coping, self-efficacy, and problem solving skills, as well as generating an indirect effect on parental well-being by targeting child developmental problems...
2017: PloS One
https://www.readbyqxmd.com/read/28094436/cartilage-hair-hypoplasia-with-normal-height-in-childhood-four-patients-with-a-unique-genotype
#17
Paula Klemetti, Helena Valta, Svetlana Kostjukovits, Mervi Taskinen, Sanna Toiviainen-Salo, Outi Mäkitie
The manifestations of cartilage-hair hypoplasia (CHH), a metaphyseal chondrodysplasia caused by RMRP mutations, include short stature, hypoplastic hair, immunodeficiency and increased risk of malignancies. Clinical features show significant variability. We report a patient with normal height until age 12.5 years (-1.6 SDS at 11 years) who was diagnosed with CHH at 14 years. RMRP sequencing revealed compound heterozygosity for g.70A>G mutation and a 10-nucleotide duplication at position -13 (TACTCTGTGA)...
January 17, 2017: Clinical Genetics
https://www.readbyqxmd.com/read/28094013/pulmonary-outcome-of-esophageal-atresia-patients-and-its-potential-causes-in-early-childhood
#18
René Dittrich, Philippe Stock, Karin Rothe, Petra Degenhardt
INTRODUCTION: The aim of this study was to illustrate the pulmonary long term outcome of patients with repaired esophageal atresia and to further examine causes and correlations that might have led to this outcome. METHODS: Twenty-seven of 62 possible patients (43%) aged 5-20years, with repaired esophageal atresia were recruited. Body plethysmography and spirometry were performed to evaluate lung function, and the Bruce protocol treadmill exercise test to assess physical fitness...
January 3, 2017: Journal of Pediatric Surgery
https://www.readbyqxmd.com/read/28093933/acute-kidney-injury-in-idiopathic-nephrotic-syndrome-of-childhood-is-a-major-risk-factor-for-the-development-of-chronic-kidney-disease
#19
Afshan Yaseen, Vina Tresa, Ali Asghar Lanewala, Seema Hashmi, Irshad Ali, Sabeeta Khatri, Muhammed Mubarak
BACKGROUND: Acute kidney injury (AKI) is an important complication of idiopathic nephrotic syndrome (INS) and is associated with adverse outcomes, especially the development of chronic kidney disease (CKD). We aimed to determine the clinical profile of children with INS who developed AKI and its short-term outcome. MATERIAL AND METHODS: This prospective study was conducted from March 2014 to October 2015. A total of 119 children of INS (age: 2-18 years) fulfilling the pediatric RIFLE criteria for the diagnosis of AKI were enrolled and followed up for 3 months to determine the outcome...
November 2017: Renal Failure
https://www.readbyqxmd.com/read/28093827/trajectories-of-sleep-and-cardiac-sympathetic-activity-indexed-by-pre-ejection-period-in-childhood
#20
Mona El-Sheikh, J Benjamin Hinnant, Lauren E Philbrook
Fragmented and insufficient sleep has been implicated in disrupted autonomic nervous system activity during resting state conditions in typically developing children. Towards explication of these relations over development, the current study tested reciprocal relations between the development of sleep parameters (efficiency, duration, latency) and cardiac sympathetic nervous system (SNS) activity indexed by pre-ejection period (PEP) during waking-resting state conditions throughout middle and late childhood...
January 17, 2017: Journal of Sleep Research
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