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https://www.readbyqxmd.com/read/29049874/balancing-bacteria-osteoblasts-competition-through-selective-physical-puncture-and-biofunctionalization-of-zno-polydopamine-arginine-glycine-aspartic-acid-cysteine-nanorods
#1
Jun Li, Lei Tan, Xiangmei Liu, Zhenduo Cui, Xianjin Yang, Kelvin Wai Kwok Yeung, Paul K Chu, Shuilin Wu
Bacterial infection and lack of bone tissue integration are two major concerns of orthopedic implants. In addition, osteoinductivity often decreases and toxicity may arise when antibacterial agents are introduced to increase the antibacterial ability. Here hybrid ZnO/polydopamine (PDA)/arginine-glycine-aspartic acid-cysteine (RGDC) nanorod (NR) arrays are designed and prepared on titanium (Ti) implants to not only enhance the osteoinductivity but also effectively kill bacteria simultaneously, which are ascribed to the selective physical puncture and the biofunctionalization of ZnO/PDA/RGDC nanorods during the competition between bacteria and osteoblasts, that is, owing to the much larger size of osteoblasts than bacteria, the hybrid NRs can puncture bacteria but not damage osteoblasts...
October 19, 2017: ACS Nano
https://www.readbyqxmd.com/read/29047241/normative-values-of-physical-examinations-commonly-used-for-cerebral-palsy
#2
Seung Jun Moon, Young Choi, Chin Youb Chung, Ki Hyuk Sung, Byung Chae Cho, Myung Ki Chung, Jaeyoung Kim, Mi Sun Yoo, Hyung Min Lee, Moon Seok Park
PURPOSE: The aim of this study was to establish normative values and to identify age-related change in physical examinations that are commonly used while evaluating patients with cerebral palsy (CP). MATERIALS AND METHODS: One hundred four healthy volunteers (mean age 36 years, standard deviation 15 years) were enrolled and divided into four age groups: 13-20, 21-35, 36-50, and 51 years and older. The eighteen physical examination tests for CP were selected by five orthopedic surgeons in consensus-building session...
November 2017: Yonsei Medical Journal
https://www.readbyqxmd.com/read/29046823/functionalization-of-ti-40nb-implant-material-with-strontium-by-reactive-sputtering
#3
Markus Göttlicher, Marcus Rohnke, Yannik Moryson, Jürgen Thomas, Joachim Sann, Anja Lode, Matthias Schumacher, Romy Schmidt, Stefan Pilz, Annett Gebert, Thomas Gemming, Jürgen Janek
BACKGROUND: Surface functionalization of orthopedic implants with pharmaceutically active agents is a modern approach to enhance osseointegration in systemically altered bone. A local release of strontium, a verified bone building therapeutic agent, at the fracture site would diminish side effects, which could occur otherwise by oral administration. Strontium surface functionalization of specially designed titanium-niobium (Ti-40Nb) implant alloy would provide an advanced implant system that is mechanically adapted to altered bone with the ability to stimulate bone formation...
2017: Biomaterials Research
https://www.readbyqxmd.com/read/29038695/deep-venous-thrombosis-among-diabetic-patients-in-king-abdulaziz-university-kau-hospital-jeddah-kingdom-of-saudi-arabia
#4
Hanan Khalid Alotaibi, Nagah Mohamed Abo El-Fetoh, Aseel MenwerAlanazi, Omar Ayed Alanazi, Abdullah Barghash Alanazi, Mohammed Ali Alhowaish, Hussam Saeed Busays Alzahrani, Mashael Abdullah Alshammari, Rawan Fulayyih ALrashidi, Thikra Mohammed Alblowi, Sarah Jemal Alqahtani, Fatin Salem Almaashi
BACKGROUND: Deep venous thrombosis (DVT) is a major cause of morbidity and mortality among hospitalized patients worldwide and, simultaneously, the most preventable. Studies revealed several risk factors of deep venous thrombosis in hospitalized patients. OBJECTIVE: to identify frequency and factors associated with occurrence of deep venous thrombosis among diabetic patients referred to King Abdulaziz University (KAU) Hospital, Jeddah, Kingdom of Saudi Arabia. METHODS: This cross-sectional hospital-based study was conducted from June to December, 2016...
September 2017: Electronic Physician
https://www.readbyqxmd.com/read/29037925/radiographic-union-scoring-scale-for-determining-consolidation-rates-in-the-calcaneus
#5
Michael L Sganga, N Jake Summers, Brandon Barrett, Michael Matthews, Timothy Karthas, Lindsay Johnson, Jeremy J Cook, Philip Basile, Emily A Cook
The reliable evaluation of osseous consolidation after hindfoot osteotomy can be difficult. Concomitant hindfoot osteotomies often dictate the advancement of weightbearing, and radiographs are the mainstay imaging tool owing to cost, efficiency, and radiation exposure. Understanding the radiographic parameters that can be used to reliably determine osseous healing is paramount. However, currently, no reliable or validated method is available to determine osseous healing of hindfoot osteotomies in irregular bones of the foot...
October 13, 2017: Journal of Foot and Ankle Surgery: Official Publication of the American College of Foot and Ankle Surgeons
https://www.readbyqxmd.com/read/29037822/how-does-level-and-type-of-experience-affect-measurement-of-joint-range-of-motion
#6
Russell R Russo, Matthew B Burn, Sabir K Ismaily, Brayden J Gerrie, Shuyang Han, Jerry Alexander, Christopher Lenherr, Philip C Noble, Joshua D Harris, Patrick C McCulloch
OBJECTIVES: Comparison of range of motion measurements by 3 types of investigators with different levels and types of training using three different measurement techniques. The study hypothesis was that the accuracy and precision of range of motion measurements would vary based on (1) the level and type of experience of the investigator and (2) the measurement technique used. DESIGN/SETTING: Descriptive laboratory study. PARTICIPANTS: Ten fresh frozen cadavers (20 upper and 20 lower extremities)...
October 13, 2017: Journal of Surgical Education
https://www.readbyqxmd.com/read/29035987/low-intensity-pulsed-ultrasound-for-early-stage-lumbar-spondylolysis-in-young-athletes
#7
Masahiro Tsukada, Toshiro Takiuchi, Kota Watanabe
OBJECTIVE: To examine the effect of low-intensity pulsed ultrasound (LIPUS) on early-stage spondylolysis in young athletes. DESIGN: Case-control study. SETTING: A single outpatient orthopedic and sports clinic. PATIENTS: A total of 82 young athletes (80 boys and 2 girls; mean age, 14.8 years; range, 10-18 years) with early-stage lumbar spondylolysis were enrolled in this study. All patients were examined by plain radiography and magnetic resonance imaging...
October 10, 2017: Clinical Journal of Sport Medicine: Official Journal of the Canadian Academy of Sport Medicine
https://www.readbyqxmd.com/read/29035127/healing-potential-of-nanohydroxyapatite-gelatin-and-fibrin-platelet-glue-combination-as-tissue-engineered-scaffolds-in-radial-bone-defects-of-rats
#8
Abdolhamid Meimandi-Parizi, Ahmad Oryan, Hojjat Gholipour
Different biomaterials have been used in orthopedic surgery. Evaluation of biomaterials for bone healing promotion has been a wide area of research of the orthopedic field. Sixty critical size defects of 5 mm long were bilaterally created in the radial diaphysis of 30 rats. The animals were randomly divided into six equal groups as empty defect, autograft, nanohydroxyapatite (nHA), Gelatin (Gel)-nHA, Fibrin-platelet glue (FPG)-nHA and Gel-FPG-nHA groups (n = 10 in each group). Radiographs of each forelimb were taken postoperatively on the 1(st) day and then at the 28(th) and 56(th) days post injury...
October 16, 2017: Connective Tissue Research
https://www.readbyqxmd.com/read/29031873/does-specialty-matter-a-survey-on-176-italian-neurosurgeons-and-orthopaedic-spine-surgeons-confirms-similar-competency-for-common-spinal-conditions-and-supports-multidisciplinary-teams-in-comprehensive-and-complex-spinal-care
#9
Matteo Pejrona, Gabriele Ristori, Jorge Hugo Villafañe, Fabrizio Ernesto Pregliasco, Pedro Berjano
BACKGROUND CONTEXT: Spine surgery is a multi-faceted sub-speciality requiring a breadth of knowledge and skill from different branches of medicine for the treatment of pathologies varying from degenerative to deformity, oncological, and trauma. PURPOSE: The aim of the study was to investigate the self-perceived competency of spine surgeons in relation to different types of spinal procedures. STUDY DESIGN/SETTING: Survey study. METHODS: We conducted a survey on 176 surgeons (Orthopaedic surgeons and Neurosurgeons)...
October 11, 2017: Spine Journal: Official Journal of the North American Spine Society
https://www.readbyqxmd.com/read/29031223/enhanced-antibacterial-activity-and-biocompatibility-of-zinc-incorporated-organic-inorganic-nanocomposite-coatings-via-electrophoretic-deposition
#10
Pin Huang, Kena Ma, Xinjie Cai, Dan Huang, Xu Yang, Jiabing Ran, Fushi Wang, Tao Jiang
Increased use of reconstruction procedures in orthopedics has improved the life of patients undergoing surgery. However, surgical site infection remains a major challenge. Efforts were made to fabricate antibacterial surfaces with good biocompatibility. This present study aimed to fabricate zinc-incorporated chitosan/gelatin (CS/G) nanocomposite coatings on the titanium substrates via electrophoretic deposition (EPD). Physicochemical characterization confirmed that zinc was successfully deposited in a metallic oxide/salt complex status...
October 6, 2017: Colloids and Surfaces. B, Biointerfaces
https://www.readbyqxmd.com/read/29025528/-evaluation-of-the-function-and-quality-of-life-after-total-hip-arthroplasty-by-different-approaches
#11
Paulo Araújo, Luís Machado, Duarte Cadavez, Lisete Mónaco, Filipa Januário, Lisete Luís, Mafalda Bártolo
INTRODUCTION: To assess the function and quality of life in patients undergoing total hip arthroplasty distinguishing two surgical approaches (posterior / anterolateral) used by the Orthopedics department of Centro Hospitalar de Leiria. MATERIAL AND METHODS: Retrospective study of 94 patients subject to unilateral hip replacement surgery, using the 'Hip Osteoarthritis Outcome Score' (HOOS LK 2.0) questionnaire, the Trendelenburg test and evaluation of muscle strength of the hip abductor muscles with dynamometer...
September 29, 2017: Acta Médica Portuguesa
https://www.readbyqxmd.com/read/29019803/the-spot-gradetm-a-new-method-for-reproducibly-quantifying-surgical-wound-bleeding
#12
William D Spotnitz, Dirk Zielske, Valerie Centis, Rachel Hoffman, Daniel L Gillen, Catherine Wittmann, Vincent Guyot, Doris M Campos, Patricia Forest, Alan Pearson, Paul C McAfee
STUDY DESIGN: Benchtop model with prospective surgeon video testing. OBJECTIVE: To create a surface bleeding severity scale, the SPOT GRADE (SG), for quantitative assessment of target bleeding site (TBS) blood loss. This is of particular interest for spinal surgery due to epidural bleeding and an inability to use diathermy and radiofrequency cautery close to nerve roots. SUMMARY OF BACKGROUND DATA: A novel apparatus perfusable at known flow rates and simulating different sized wounds was used to create movies to educate surgeons on specific degrees of bleeding...
October 10, 2017: Spine
https://www.readbyqxmd.com/read/29019535/what-is-the-ideal-working-length-for-bridge-plating-osteosynthesis-of-a-femoral-shaft-fracture-a-multinational-online-survey-evaluation
#13
Vincenzo Giordano, Roger Pletsch Paes, Gustavo Barbosa de-Queiroz, José Claudio Lira, William Dias Belangero, Robinson Esteves Santos Pires, Pedro José Labronici
OBJECTIVE: to evaluate how orthopedic surgeons in Latin America define the working length for distinct patterns of femoral shaft fracture. METHODS: a survey was developed presenting different options of working length in four femoral fracture patterns. The survey was submitted to the participants using Google Forms tool. The association between professional characteristics and medical management options according to each type of fracture was analyzed by Chi-square test, with 5% significance level...
July 2017: Revista do Colégio Brasileiro de Cirurgiões
https://www.readbyqxmd.com/read/29017475/reliability-validity-and-responsiveness-of-the-german-self-reported-foot-and-ankle-score-sefas-in-patients-with-foot-or-ankle-surgery
#14
Dariusch Arbab, Katharina Kuhlmann, Christoph Schnurr, Bertil Bouillon, Christian Lüring, Dietmar König
BACKGROUND: Patient-reported outcome measures are a critical tool in evaluating the efficacy of orthopedic procedures and are increasingly used in clinical trials to assess outcomes of health care. The intention of this study was to develop and culturally adapt a German version of the Self-reported Foot and Ankle Score (SEFAS) and to evaluate reliability, validity and responsiveness. METHODS: According to Cross Cultural Adaptation of Self-Reported Measure guidelines forward and backward translation has been performed...
October 10, 2017: BMC Musculoskeletal Disorders
https://www.readbyqxmd.com/read/28993088/hip-and-knee-arthroplasty-orthopedic-literature-in-medical-journals-is-it-negatively-biased
#15
Ronald E Delanois, Chukwuweike U Gwam, Nicolas S Piuzzi, Morad Chughtai, Arthur L Malkani, Peter M Bonutti, Michael A Mont
BACKGROUND: Healthcare policy is often determined by well-designed studies most often published in high-impact medical journals. However, concern about the presence of publication bias against lower-extremity arthroplasty-related studies has called into question some of the validity of certain reports. There are only a few studies investigating the presence of the bias in high-impact medical journals against lower-extremity arthroplasty intervention, particularly in the Journal of American Medical Association (JAMA), New England Journal of Medicine (NEJM), and the Lancet...
September 19, 2017: Journal of Arthroplasty
https://www.readbyqxmd.com/read/28992487/agnps-decorated-3d-printed-peek-implant-for-infection-control-and-bone-repair
#16
Lijun Deng, Yi Deng, Kenan Xie
Polyetheretherketone (PEEK) is an ideal substitute material for bone tissue engineering, which can avoid the stress shielding phenomenon due to its similar mechanical properties to natural human bone. Complex bone defect and postoperative infection are still two enormous challenges in orthopedic clinics. It's well-known that additive manufacturing possesses the merits of high-precision and rapid prototyping, thus it easily meets the needs of mold processing. In the present study, we developed a novel Ag-decorated 3D printed PEEK via catecholamine chemistry...
October 2, 2017: Colloids and Surfaces. B, Biointerfaces
https://www.readbyqxmd.com/read/28992148/inappropriate-hospital-days-of-a-tertiary-hospital-in-shanghai-china
#17
Wenwei Liu, Suwei Yuan, Fengqing Wei, Jing Yang, Changbin Zhu, Y Yu, Jin Ma
Objective: This study aims to evaluate the prevalence of inappropriate hospital stays in a tertiary hospital in Shanghai, identify the causes for the inappropriateness and analyze the predictors. Design: A retrospective review of medical records. Setting: The cardiology and the orthopedics departments of a tertiary hospital in Shanghai, China. Participants: About 806 patients discharged from the cardiology or the orthopedics department of a tertiary hospital from March 2013 to February 2014...
October 1, 2017: International Journal for Quality in Health Care
https://www.readbyqxmd.com/read/28983666/assessment-of-reliability-validity-responsiveness-and-minimally-important-change-of-the-german-hip-dysfunction-and-osteoarthritis-outcome-score-hoos-in-patients-with-osteoarthritis-of-the-hip
#18
Dariusch Arbab, Johannes H M van Ochten, Christoph Schnurr, Bertil Bouillon, Dietmar König
Patient-reported outcome measures are a critical tool in evaluating the efficacy of orthopedic procedures. The intention of this study was to evaluate reliability, validity, responsiveness and minimally important change of the German version of the Hip dysfunction and osteoarthritis outcome score (HOOS). The German HOOS was investigated in 251 consecutive patients before and 6 months after total hip arthroplasty. All patients completed HOOS, Oxford-Hip Score, Short-Form (SF-36) and numeric scales for pain and disability...
October 5, 2017: Rheumatology International
https://www.readbyqxmd.com/read/28983217/the-incidence-of-perioperative-cardiac-events-after-orthopedic-surgery-a-single-institutional-experience-of-cases-performed-over-one-year
#19
Michael K Urban, Steffan W Wolfe, Neil M Sanghavi, Kara Fields, Steven K Magid
BACKGROUND: Orthopedic patients with ischemic heart disease are at risk for postoperative cardiac complications. QUESTIONS/PURPOSES: Using information from two medical information retrieval systems which insured the capture of all events for the period of study, our goals were to determine the incidence of myocardial injury in at-risk patients after orthopedic surgery and to delineate the type and incidence of cardiac complications in this population. METHODS: For one year, at an orthopedic hospital, we identified all postoperative patients with a measured cTnI level using an electronic ordering system...
October 2017: HSS Journal: the Musculoskeletal Journal of Hospital for Special Surgery
https://www.readbyqxmd.com/read/28977869/prognostic-value-of-the-c-reactive-protein-prognostic-nutritional-index-ratio-after-hip-fracture-surgery-in-the-elderly-population
#20
Hanru Ren, Lianghao Wu, Wankun Hu, Xiuzhang Ye, Baoqing Yu
BACKGROUND: More and more older patients receive the surgery after hip fracture. However, the mortality rate is high. Prognostic nutritional index (PNI) is associated with prognosis in hip fracture patients. In the current study, we proposed a novel prognostic score, named c-reactive protein/PNI ratio (CRP/PNI ratio), for predicting the prognosis for geriatric orthopedic population. METHODS: This is a prospective study. Eighty cases of hip fracture surgery in the elderly population were studied to reveal the relationship between the CRP/PNI ratio and the clinicopathological characteristics of the elderly patients...
September 22, 2017: Oncotarget
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