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https://www.readbyqxmd.com/read/28319734/novel-mechanical-impact-simulator-designed-to-generate-clinically-relevant-anterior-cruciate-ligament-ruptures
#1
Nathaniel A Bates, Nathan D Schilaty, Christopher V Nagelli, Aaron J Krych, Timothy E Hewett
BACKGROUND: Over 250,000 anterior cruciate ligament ruptures occur each year; therefore, it is important to understand the underlying mechanisms of these injuries. The objective of the current investigation was to develop and analyze an impact test device that consistently produces anterior cruciate ligament failure in a clinically relevant manner. METHOD: A mechanical impact simulator was developed to simulate the ground reaction force impulse generated from landing in a physiologic and clinically relevant manner...
March 10, 2017: Clinical Biomechanics
https://www.readbyqxmd.com/read/28318864/weight-gain-after-primary-total-knee-arthroplasty-is-associated-with-accelerated-time-to-revision-for-aseptic-loosening
#2
Chin Tat Lim, Stuart B Goodman, James I Huddleston, Alex H S Harris, Subhrojyoti Bhowmick, William J Maloney, Derek F Amanatullah
BACKGROUND: Obesity is a major health problem worldwide and is associated with complications after total knee arthroplasty (TKA). It remains unknown whether a change in body mass index (BMI) after primary TKA affects the reasons for revision TKA or the time to revision TKA. METHODS: A total of 160 primary TKAs referred to an academic tertiary center for revision TKA were retrospectively stratified according to change in BMI from the time of their primary TKA to revision TKA...
February 20, 2017: Journal of Arthroplasty
https://www.readbyqxmd.com/read/28298758/comparison-of-analgesic-efficacy-of-dexmedetomidine-and-midazolam-as-adjuncts-to-lignocaine-for-intravenous-regional-anesthesia
#3
Bharti Gupta, Ravinder Kumar Verma, Sudershan Kumar, Geeta Chaudhary
BACKGROUND: Intravenous regional anesthesia (IVRA) is safe, technically simple, and cost-effective technique compared to general anesthesia with success rates of 94-98% for upper and lower limb surgeries. The main disadvantage of this procedure is its limited duration for surgery, lack of postoperative analgesia, and tourniquet pain. To overcome this disadvantage, various adjuvants to lignocaine have been studied from time to time. AIM: To compare the analgesic efficacy of dexmedetomidine and midazolam as adjuncts to lignocaine for IVRA for forearm and hand surgeries...
January 2017: Anesthesia, Essays and Researches
https://www.readbyqxmd.com/read/28298756/comparison-of-postoperative-pain-after-epidural-anesthesia-using-0-5-0-75-ropivacaine-and-0-5-bupivacaine-in-patients-undergoing-lower-limb-surgery-a-double-blind-study
#4
Tripat Kaur Bindra, Rajvinder Singh, Ruchi Gupta
BACKGROUND: Ropivacaine (S (-)-1-propyl-2", 6"; pipecoloxylidide hydrochloride) a newer long-acting amide local anesthetic has various clinical and pharmacokinetic advantages over bupivacaine. AIMS: The aim of this study is to compare the onset as well as the duration of sensory block, hemodynamic variables, and postoperative analgesia with 0.5%, 0.75% ropivacaine and 0.5% bupivacaine after epidural anesthesia for lower limb orthopedic surgery. PATIENTS AND METHODS: Sixty American Society of Anesthesiologists I and II patients scheduled for lower limb orthopedic surgery were enrolled into this randomized, double-blind study...
January 2017: Anesthesia, Essays and Researches
https://www.readbyqxmd.com/read/28296515/risk-preferences-and-attitudes-to-surgery-in-decision-making
#5
Andreas Meunier, Kinga Posadzy, Gustav Tinghög, Per Aspenberg
Background and purpose - There is increasing evidence that several commonly performed surgical procedures provide little advantage over nonoperative treatment, suggesting that doctors may sometimes be inappropriately optimistic about surgical benefit when suggesting treatment for individual patients. We investigated whether attitudes to risk influenced the choice of operative treatment and nonoperative treatment. Methods - 946 Swedish orthopedic surgeons were invited to participate in an online survey. A radiograph of a 4-fragment proximal humeral fracture was presented together with 5 different patient characteristics, and the surgeons could choose between 3 different operative treatments and 1 nonoperative treatment...
March 15, 2017: Acta Orthopaedica
https://www.readbyqxmd.com/read/28295123/new-proximal-femoral-compaction-blade-provides-strong-antirotation-stability-of-the-femoral-head
#6
Shinya Hayashi, Yukiaki Hirata, Daiki Okamoto, Satoshi Kakunai, Shingo Hashimoto, Koji Takayama, Tomoyuki Matsumoto, Takahiro Niikura, Takaaki Fujishiro, Takafumi Hiranaka, Kotaro Nishida, Ryosuke Kuroda
This study investigated the mechanical properties of a new rectangular compaction blade and compared this blade with other types of nail. Three types of nail were tested: the Magnum lag screw (Robert Reid Inc, Tokyo, Japan), proximal femoral nail, and Magnum Fid blade (Robert Reid Inc). The nails were inserted into solid rigid polyurethane foam, and the torsional moments were loaded with an Instron testing machine (Instron, Kanagawa, Japan). The force curve was recorded, and the average maximum torque was calculated from this curve...
March 14, 2017: Orthopedics
https://www.readbyqxmd.com/read/28295122/epiphysiodesis-screw-bending
#7
Brett M Normandin, David J Tennent, Todd H Baldini, Alesia M Blanchard, Jason T Rhodes
Percutaneous epiphysiodesis using transphyseal screws is a common method for treatment of limb length discrepancy and angular deformity. The authors report 3 cases of a previously unreported complication following treatment with percutaneous epiphysiodesis using transphyseal screws: bending of the transphyseal screw. In each case, this rare complication was associated with difficult removal of the screw. This retrospective case report accessed the medical records of 3 children, 2 boys and 1 girl, 9 to 14 years old...
March 14, 2017: Orthopedics
https://www.readbyqxmd.com/read/28287922/co-seeding-human-endothelial-cells-with-human-induced-pluripotent-stem-cell-derived-mesenchymal-stem-cells-on-calcium-phosphate-scaffold-enhances-osteogenesis-and-vascularization-in-rats
#8
Xian Liu, Wenchuan Chen, Chi Zhang, Wahwah Thein-Han, Kevin Hu, Mark A Reynolds, Chongyun Bao, Ping Wang, Liang Zhao, Hockin H K Xu
A major challenge in repairing large bone defects with tissue-engineered constructs is the poor vascularization in the defect. The lack of vascular networks leads to insufficient oxygen and nutrients supply, which compromises the survival of seeded cells. To achieve favorable regenerative effects, prevascularization of tissue-engineered constructs by co-culturing of endothelial cells and bone cells is a promising strategy. The aim of this study was to investigate the effects of human-induced pluripotent stem cell-derived mesenchymal stem cells (hiPSC-MSCs) co-cultured with human umbilical vein endothelial cells (HUVECs) for prevascularization of calcium phosphate cement (CPC) scaffold on bone regeneration in vivo for the first time...
March 10, 2017: Tissue Engineering. Part A
https://www.readbyqxmd.com/read/28284367/-career-satisfaction-of-german-medical-residents-after-four-years-of-training
#9
Farina Römer, Stine Ziegler, Martin Scherer, Hendrik van den Bussche
OBJECTIVE: To evaluate German residents' career satisfaction and its dependency on intrinsic and extrinsic factors after four years of postgraduate training. Gender, parental status, training conditions and specialty choice were of particular interest. METHODS: Postal questionnaires were sent to medical graduates from seven different German faculties annually, starting in 2009. This paper presents cross-sectional data of domestic, working and training conditions four years after graduation...
February 2017: Zeitschrift Für Evidenz, Fortbildung und Qualität Im Gesundheitswesen
https://www.readbyqxmd.com/read/28283375/psychomotor-testing-for-orthopedic-residency-applicants-a-pilot-study
#10
Johnathan F Williams, Shawna L Watson, Dustin K Baker, Brent A Ponce, Gerald McGwin, Shawn R Gilbert, Joseph G Khoury
OBJECTIVE: The purpose of this study was to develop an objective motor skills testing system to aid in the evaluation of potential orthopedic residents. DESIGN: Participants attempted a battery of 5 motor skills tests (4 novel tests and the Grooved Pegboard [GPT] Test) in one 10-minute session. A percentile-based scoring system was created for each test based on raw scores. One-way analysis of variance was used to compare testing scores among 3 cohorts. Each novel test and overall scores were compared with GPT scores as a relative measure of validity...
March 7, 2017: Journal of Surgical Education
https://www.readbyqxmd.com/read/28283030/impaired-osteogenesis-of-t1dm-bone-marrow-derived-stromal-cells-and-periosteum-derived-cells-and-their-differential-in-vitro-responses-to-growth-factor-rescue
#11
Tera M Filion, Jordan D Skelly, Henry Huang, Dale L Greiner, David C Ayers, Jie Song
BACKGROUND: Poor bone quality, increased fracture risks, and impaired bone healing are orthopedic comorbidities of type 1 diabetes (T1DM). Standard osteogenic growth factor treatments are inadequate in fully rescuing retarded healing of traumatic T1DM long bone injuries where both periosteal and bone marrow niches are disrupted. We test the hypotheses that osteogenesis of bone marrow-derived stromal cells (BMSCs) and periosteum-derived cells (PDCs), two critical skeletal progenitors in long bone healing, are both impaired in T1DM and that they respond differentially to osteogenic bone morphogenetic proteins (BMPs) and/or insulin-like growth factor-1 (IGF-1) rescue...
March 11, 2017: Stem Cell Research & Therapy
https://www.readbyqxmd.com/read/28280714/anti-biofilm-activity-of-a-long-chain-fatty-aldehyde-from-antarctic-pseudoalteromonas-haloplanktis-tac125-against-staphylococcus-epidermidis-biofilm
#12
Angela Casillo, Rosanna Papa, Annarita Ricciardelli, Filomena Sannino, Marcello Ziaco, Marco Tilotta, Laura Selan, Gennaro Marino, Maria M Corsaro, Maria L Tutino, Marco Artini, Ermenegilda Parrilli
Staphylococcus epidermidis is a harmless human skin colonizer responsible for ~20% of orthopedic device-related infections due to its capability to form biofilm. Nowadays there is an interest in the development of anti-biofilm molecules. Marine bacteria represent a still underexploited source of biodiversity able to synthesize a broad range of bioactive compounds, including anti-biofilm molecules. Previous results have demonstrated that the culture supernatant of Antarctic marine bacterium Pseudoalteromonas haloplanktis TAC125 impairs the formation of S...
2017: Frontiers in Cellular and Infection Microbiology
https://www.readbyqxmd.com/read/28274193/a-peptide-based-biological-coating-for-enhanced-corrosion-resistance-of-titanium-alloy-biomaterials-in-chloride-containing-fluids
#13
Noah Muruve, Yuanchao Feng, Jaye Platnich, Daniel Hassett, Randall Irvin, Daniel Muruve, Frank Cheng
Titanium alloys are common materials in the manufacturing of dental and orthopedic implants. Although these materials exhibit excellent biocompatibility, corrosion in response to biological fluids can impact prosthesis performance and longevity. In this work, a PEGylated metal binding peptide (D-K122-4-PEG), derived from bacteria Pseudomonas aeruginosa, was applied on a titanium (Ti) alloy, and the corrosion resistance of the coated alloy specimen was investigated in simulated chloride-containing physiological fluids by electrochemical impedance spectroscopy and micro-electrochemical measurements, surface characterization, and biocompatibility testing...
March 2017: Journal of Biomaterials Applications
https://www.readbyqxmd.com/read/28271087/comparison-of-pediatric-and-general-orthopedic-surgeons-approaches-in-management-of-developmental-dysplasia-of-the-hip-and-flexible-flatfoot-the-road-to-clinical-consensus
#14
Ramin Haj Zargarbashi, Hirbod Nasiri Bonaki, Shayan Abdollah Zadegan, Taghi Baghdadi, Mohammad Hossein Nabian, Mehdi Ramezan Shirazi
Developmental dysplasia of the hip (DDH) and flatfoot are common pediatric orthopedic disorders, being referred to and managed by both general and pediatric orthopedic surgeons, through various modalities. Our study aimed to evaluate their consensus and perspective disagreements in terms of diagnostic and therapeutic approaches of the mentioned deformities. Forty participants in two groups of general orthopedic surgeons (GOS) (n=20) and pediatric orthopedic surgeons (POS) (n=20), were asked to answer an 8-item questionnaire on DDH and flexible flatfoot...
January 2017: Archives of Bone and Joint Surgery
https://www.readbyqxmd.com/read/28269683/classification-of-squat-quality-with-inertial-measurement-units-in-the-single-leg-squat-mobility-test
#15
Rezvan Kianifar, Alex Lee, Sachin Raina, Dana Kulic
Many assessment and diagnosis protocols in rehabilitation, orthopedic surgery and sports medicine rely on mobility tests like the Single Leg Squat (SLS). In this study, a set of three Inertial Measurement Units (IMUs) were used to estimate the joint pose during SLS and to classify the SLS as poor, moderate or good. An Extended Kalman Filter pose estimation method was used to estimate kinematic joint variables, and time domain features were generated based on these variables. The most important features were then selected and used to train Support Vector Machine (SVM), Linear Multinomial Logistic Regression, and Decision Tree classifiers...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28269319/design-and-pilot-evaluation-of-competitive-and-cooperative-exercise-games-for-arm-rehabilitation-at-home
#16
Maja Gorsic, Domen Novak
People with chronic arm impairment should exercise intensely at home after completing their clinical rehabilitation program, but frequently lack motivation. To address this issue, we present a home rehabilitation system that motivates patients by allowing them to perform arm exercises together with friends or relatives in competitive and cooperative games. Inertial sensors are used to track the patient's arm and control the game. The system was tested with seven adults with arm impairment as well as their friends or spouses...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28268705/reducing-the-effect-of-parasitic-capacitance-on-implantable-passive-resonant-sensors
#17
John F Drazan, Omar T Abdoun, Michael T Wassick, George A Marcus, Reena Dahle, Luke A Beardslee, Nathaniel C Cady, Eric H Ledet
Passive, LC resonators have the potential to serve as small, robust, low cost, implantable sensors to wirelessly monitor implants following orthopedic surgery. One significant barrier to using LC sensors is the influence on the sensor's resonance of the surrounding conductive high permittivity media in vivo. The surrounding media can detune the resonant frequency of the LC sensor resulting in a bias. To mitigate the effects of the surrounding media, we added a "capping layer" to LC sensors to isolate them from the surrounding media...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28267662/microstructure-and-property-evolutions-of-titanium-nano-hydroxyapatite-composites-in-situ-prepared-by-selective-laser-melting
#18
Changjun Han, Qian Wang, Bo Song, Wei Li, Qingsong Wei, Shifeng Wen, Jie Liu, Yusheng Shi
Titanium (Ti)-hydroxyapatite (HA) composites have the potential for orthopedic applications due to their favorable mechanical properties, excellent biocompatibility and bioactivity. In this work, the pure Ti and nano-scale HA (Ti-nHA) composites were in-situ prepared by selective laser melting (SLM) for the first time. The phase, microstructure, surface characteristic and mechanical properties of the SLM-processed Ti-nHA composites were studied by X-ray diffraction, transmission electron microscope, atomic force microscope and tensile tests, respectively...
February 20, 2017: Journal of the Mechanical Behavior of Biomedical Materials
https://www.readbyqxmd.com/read/28266885/the-design-implementation-and-evaluation-of-a-physiotherapist-led-clinic-for-orthopedic-surveillance-for-children-with-cerebral-palsy
#19
Karen Hurtubise, Robin Shanks, Laura Benard
AIM: To describe the development process and the evaluation results of a new physiotherapy-led clinic for orthopedic monitoring of secondary impairments for children with cerebral palsy (CP). METHODS: A new clinic model was developed and implemented, guided by the Framework for the Development of Advanced Practice Roles and the Model for Improvement. Patient visits and wait-time statistics were measured during the implementation phase. Once implemented, an evaluation of the clinic model objectives was conducted...
March 7, 2017: Physical & Occupational Therapy in Pediatrics
https://www.readbyqxmd.com/read/28266107/refining-patterns-of-joint-hypermobility-habitus-and-orthopedic-traits-in-joint-hypermobility-syndrome-and-ehlers-danlos-syndrome-hypermobility-type
#20
Silvia Morlino, Chiara Dordoni, Isabella Sperduti, Marina Venturini, Claudia Celletti, Filippo Camerota, Marina Colombi, Marco Castori
Joint hypermobility syndrome (JHS) and Ehlers-Danlos syndrome, hypermobility type (EDS-HT) are two overlapping heritable disorders (JHS/EDS-HT) recognized by separated sets of diagnostic criteria and still lack a confirmatory test. This descriptive research was aimed at better characterizing the clinical phenotype of JHS/EDS-HT with focus on available diagnostic criteria, and in order to propose novel features and assessment strategies. One hundred and eighty-nine (163 females, 26 males; age: 2-73 years) patients from two Italian reference centers were investigated for Beighton score, range of motion in 21 additional joints, rate and sites of dislocations and sprains, recurrent soft-tissue injuries, tendon and muscle ruptures, body mass index, arm span/height ratio, wrist and thumb signs, and 12 additional orthopedic features...
March 7, 2017: American Journal of Medical Genetics. Part A
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