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https://www.readbyqxmd.com/read/29236070/lc-ms-ms-tandem-mass-spectrometry-for-analysis-of-phenolic-compounds-and-pentacyclic-triterpenes-in-antifungal-extracts-of-terminalia-brownii-fresen
#1
Enass Y A Salih, Pia Fyhrquist, Ashraf M A Abdalla, Abdelazim Y Abdelgadir, Markku Kanninen, Marketta Sipi, Olavi Luukkanen, Mustafa K M Fahmi, Mai H Elamin, Hiba A Ali
Decoctions and macerations of the stem bark and wood of Terminalia brownii Fresen. are used in traditional medicine for fungal infections and as fungicides on field crops and in traditional granaries in Sudan. In addition, T. brownii water extracts are commonly used as sprays for protecting wooden houses and furniture. Therefore, using agar disc diffusion and macrodilution methods, eight extracts of various polarities from the stem wood and bark were screened for their growth-inhibitory effects against filamentous fungi commonly causing fruit, vegetable, grain and wood decay, as well as infections in the immunocompromised host...
December 13, 2017: Antibiotics
https://www.readbyqxmd.com/read/29235047/anthelmintic-effects-of-indigenous-multipurpose-fodder-tree-extracts-against-haemonchus-contortus
#2
Ashenafi Assefa, Yisehak Kechero, Taye Tolemariam, Assefa Kebede, Eshetu Shumi
Condensed tannins (CT) extracted from Balanites aegyptiaca, Tamarindus indica, and Celtis toka browses were used to evaluate their anthelmintic effect on different developmental stages of Haemonchus contortus. To achieve this objective, various serial concentrations of each CT extract of the foliages were used to test adult motility, inhibition of egg hatchability, and larval development. The fodders were selected based on their multipurpose advantage and accessibility to use as fodder for livestock in the low lands of the Gambella region...
December 12, 2017: Tropical Animal Health and Production
https://www.readbyqxmd.com/read/29234699/dataset-on-analysis-of-dyeing-property-of-natural-dye-from-thespesia-populnea-bark-on-different-fabrics
#3
Kuchekar Mohini, Landge Tejashree, Navghare Vijay
The natural dyes separated from plants are of gaining interest as substitutes for synthetic dyes in food and cosmetics. Thespesia populnea (T. populnea) is widely grown plant and used in the treatment of various diseases. This study was aimed to separate natural dye from T. populnea bark and analysis of its dyeing property on different fabrics. In this investigation pharmacognostic study was carried out. The pharmacognostic study includes morphological study, microscopical examination, proximate analysis along with the phytochemical study...
February 2018: Data in Brief
https://www.readbyqxmd.com/read/29234697/valorization-of-a-plant-%C3%AE-amylase-immobilization-and-dataset-on-the-kinetic-process
#4
Imen Lahmar, Greta Radeva, Dessislava Marinkova, Maya Velitchkova, Hafedh Belghith, Ferjani Ben Abdallah, Lyubov Yotova, Karima Belghith
The data presented in this article are related to the research article titled "Immobilization nd topochemical mechanism of a new β-amylase extracted from Pergularia tomentosa" (Lahmar et al., 2017) [1]. This article documented information on the determination of the molecular weight of the β-amylase, the method of its immobilization and a comparison of the kinetic mechanism between the free and the immobilized forms by a mathematical method. Fresh Pergularia tomentosa was collected from Tunisia and a special method for β-amylase extraction was followed (Yotova et al...
February 2018: Data in Brief
https://www.readbyqxmd.com/read/29234683/antioxidant-potential-of-selected-korean-edible-plant-extracts
#5
Yaejin Woo, Hyeji Lee, Yong-Seob Jeong, Ga Young Shin, Ja Gyeong Oh, Jong-Sang Kim, Jisun Oh
This study aimed to evaluate the antioxidant activity of various plant extracts. A total of 94 kinds of edible plant extracts obtained from the Korea Plant Extract Bank were screened for cytotoxicity, following which the total phenolic content of 24 shortlisted extracts was determined. Of these, extracts from three plants, namely, Castanea crenata (CC) leaf, Camellia japonica (CJ) fruit, and Viburnum dilatatum (VD) leaf, were examined for antioxidant capabilities by measuring radical scavenging activity, ferric reducing/antioxidant power, and lipid peroxidation inhibitory activity...
2017: BioMed Research International
https://www.readbyqxmd.com/read/29234604/longitudinal-survey-of-lead-cadmium-and-copper-in-seagrass-syringodium-filiforme-from-a-former-bombing-range-vieques-puerto-rico
#6
Elba Díaz, Dustin Pérez, Johanna Delgado Acevedo, Arturo Massol-Deyá
Trace element composition in plant biomass could be used as an indicator of environmental stress, management practices and restoration success. A longitudinal study was conducted to compare Pb, Cd, and Cu content in seagrass Syringodium filiforme collected at a former bombing range in Puerto Rico with those of a Biosphere Reserve under similar geoclimatic conditions. Trace elements were measured by atomic absorption after dry-ashing of samples and extraction with acid. In general, levels of Pb, Cd, and Cu varied during 2001, 2003, 2005-2006, and 2013-2016...
2018: Toxicology Reports
https://www.readbyqxmd.com/read/29234602/neutralization-of-naja-naja-venom-induced-lethality-edema-and-myonecrosis-by-ethanolic-root-extract-of-coix-lacryma-jobi
#7
K S Rajesh, B R Bharath, C V Rao, K I Bhat, K S Chandrashekhar Bhat, Pritesh Bhat
Coix lacryma-jobi, commonly known as job's tear, is a tall grain-bearing tropical plant of the family Poaceae. The ethanolic root extract (ERE) of the plant was investigated for the first time for anti-venom activity against Indian cobra Naja naja venom. In-vitro studies were conducted to determine neutralization of phospholipase A2 (PLA2) activity of the Naja naja venom by the ERE. ERE showed significant inhibition of PLA2 activity, which was further confirmed from effective neutralization of human red blood cells (HRBC) lysis induced by the venom...
2017: Toxicology Reports
https://www.readbyqxmd.com/read/29234421/comparative-phytochemical-profiling-and-in-vitro-antioxidant-activity-of-extracts-from-raw-materials-tissue-cultured-plants-and-callus-of-oroxylum-indicum-l-vent
#8
Piyanuch Rojsanga, Somnuk Bunsupa, Adelheid H Brantner, Pongtip Sithisarn
Extracts from raw materials from different plant parts, tissue-cultured plants, and callus cultures of Oroxylum indicum were analyzed for in vitro antioxidant activities determined by DPPH radical scavenging assay and evaluated for phytochemical profiles by TLC and LC-MS methods. The results were analyzed by principal component analysis (PCA) to evaluate the similarity. Stalk, pedicel, flower, seed, and whole fruit and callus extracts promoted strong antioxidant activity with high total phenolic and total flavonoid contents...
2017: Evidence-based Complementary and Alternative Medicine: ECAM
https://www.readbyqxmd.com/read/29234387/antioxidant-activity-of-a-geopropolis-from-northeast-brazil-chemical-characterization-and-likely-botanical-origin
#9
Joselena M Ferreira, Caroline C Fernandes-Silva, Antonio Salatino, Dejair Message, Giuseppina Negri
Geopropolis is a product containing wax, plant resin, and soil particles. It is elaborated by stingless bees of tribe Meliponini. Methanol extracts of sample of geopropolis produced by Scaptotrigona postica ("mandaguari") in the state of Rio Grande do Norte (RN, northeast Brazil) were analyzed for the determination of standard parameters (total phenols, total flavonoids, and radical scavenging activity) and chemical characterization by HPLC-DAD-MS/MS analysis. The sample analyzed has high contents of total phenols and flavonoids, as well as high antioxidant activity...
2017: Evidence-based Complementary and Alternative Medicine: ECAM
https://www.readbyqxmd.com/read/29234282/effect-of-methanolic-extract-of-dandelion-roots-on-cancer-cell-lines-and-amp-activated-protein-kinase-pathway
#10
Gauhar Rehman, Muhammad Hamayun, Amjad Iqbal, Sumera Afzal Khan, Hamayoon Khan, Adeeb Shehzad, Abdul Latif Khan, Anwar Hussain, Ho-Youn Kim, Jamshaid Ahmad, Ayaz Ahmad, Abid Ali, In-Jung Lee
Ethnomedicinal knowledge of plant-derived bioactives could help us in discovering new therapeutic compounds of great potential. Certainly, dandelion has been used in traditional ethno-medicinal systems (i.e., Chinese, Arabian, Indian, and Native American) to treat different types of cancer. Though, dandelion is highly vigorous, but the potential mode of action is still unclear. In the current study, the antiproliferative activity of methanolic extracts of dandelion root (MEDr) on cell viability of HepG2, MCF7, HCT116, and normal Hs27 was investigated...
2017: Frontiers in Pharmacology
https://www.readbyqxmd.com/read/29234273/indirubin-derivative-7-bromoindirubin-3-oxime-7bio-attenuates-a%C3%AE-oligomer-induced-cognitive-impairments-in-mice
#11
Liping Chen, Chunhui Huang, Jieyi Shentu, Minjun Wang, Sicheng Yan, Fei Zhou, Zaijun Zhang, Chuang Wang, Yifan Han, Qinwen Wang, Wei Cui
Indirubins are natural occurring alkaloids extracted from indigo dye-containing plants. Indirubins could inhibit various kinases, and might be used to treat chronic myelocytic leukemia, cancer and neurodegenerative disorders. 7-bromoindirubin-3-oxime (7Bio), an indirubin derivative derived from indirubin-3-oxime, possesses inhibitory effects against cyclin-dependent kinase-5 (CDK5) and glycogen synthase kinase-3β (GSK3β), two pharmacological targets of Alzheimer's disease (AD). In this study, we have discovered that 2...
2017: Frontiers in Molecular Neuroscience
https://www.readbyqxmd.com/read/29232753/solvent-extraction-and-gc-ms-analysis-of-sesame-seeds-for-determination-of-bioactive-antioxidant-fatty-acid-fatty-oil-components
#12
Abdul Qadir, Athar Ali, Muhammad Arif, Abdulmohsen H Al-Rohaimi, Satya Prakash Singh, Usama Ahmad, Mohd Khalid, Arun Kumar
The seed kernels of Sesamum indicum L. (family: Pedaliaceae) were extracted with ethanol and yield of components determined by Gas Chromatography/Mass Spectrometry (GC/MS). The free radical scavenging activities of ethanolic extract against1, 1-Diphenyl-2-picrylhydrazyl (DPPH) were determined by UV spectrophotometer at 517 nm. Phytochemical screening revealed the presence of numerous bioactive compounds including steroids, phenolic, terpenoids, fatty acids and different types of ester compounds. The ethanolic extract was purified and analyzed by GC MS...
December 12, 2017: Drug Research
https://www.readbyqxmd.com/read/29232626/targeted-isolation-and-identification-of-bioactive-compounds-lowering-cholesterol-in-the-crude-extracts-of-crabapples-using-uplc-dad-ms-spe-nmr-based-on-pharmacology-guided-pls-da
#13
Chao Wen, Dongshan Wang, Xing Li, Tao Huang, Cheng Huang, Kaifeng Hu
The anti-hyperlipidemic effects of crude crabapple extracts derived from Malus 'Red jade', Malus hupehensis (Pamp.) Rehd. and Malus prunifolia (Willd.) Borkh. were evaluated on high-fat diet induced obese (HF DIO) mice. The results revealed that some of these extracts could lower serum cholesterol levels in HF DIO mice. The same extracts were also parallelly analyzed by LC-MS in both positive and negative ionization modes. Based on the pharmacological results, 22 LC-MS variables were identified to be correlated with the anti-hyperlipidemic effects using partial least square discriminant analysis (PLS-DA) and independent samples t-test...
December 2, 2017: Journal of Pharmaceutical and Biomedical Analysis
https://www.readbyqxmd.com/read/29232614/evaluation-of-carbon-nanotube-based-copper-nanoparticle-composite-for-the-efficient-detection-of-agroviruses
#14
Muhammad Ali Tahir, Sadia Z Bajwa, Shahid Mansoor, Rob W Briddon, Waheed S Khan, Brian E Scheffler, Imran Amin
We report a biosensor that combines the construction of a three-dimensional nanocomposite with electrochemical methods for the detection of viruses in plants. This is the first report, where carbon nanotubes are used as a conductive frame to anchor highly electrolytic agglomerates of copper nanoparticles to detect agroviruses. Morphological analysis of nanocomposite revealed the presence of carbon nanotubes having a diameter of 50-100nm with copper nanoparticles of 20-100nm, attached in the form of bunches...
December 5, 2017: Journal of Hazardous Materials
https://www.readbyqxmd.com/read/29232612/aliphatic-hydrocarbons-recovered-in-vegetables-from-soils-based-on-their-in-situ-distribution-in-various-soil-humus-fractions-using-a-successive-extraction-method
#15
Juan Zhang, Shu-Kai Fan, Ming-Hua Zhang, Michael L Grieneisen, Jian-Feng Zhang
Aliphatic hydrocarbons (AHs) are major petroleum contaminants in the environment. In this study, the AHs bound to various soil endogenetic humus fractions were separated through successive extraction. Most of the AHs (46.1%) in soils were adsorbed onto/into humic acids (HA) and a small quantity of AHs (9.6%) were organic solvent extractable. AHs in B. chinensis were also analyzed since their potential risks to the residents through ingestion. AHs from C21 to C34, so called high molecular weight AHs (HMWAHs), were dominant AHs in B...
December 6, 2017: Journal of Hazardous Materials
https://www.readbyqxmd.com/read/29232609/influence-of-direct-and-sequential-extraction-methodology-on-metabolic-profiling
#16
K M Maria John, James Harnly, Devanand Luthria
A systematic comparison was made of the detected metabolite profiles for two plant materials (black beans and soybeans) and a dietary supplement (black cohosh) extracted using sequential (hexane, ethyl acetate, and 50% aqueous methanol) and direct extraction with three solvent systems (80% aqueous methanol, methanol/chloroform/water (2.5:1:1, v/v/v) and water). Extracts were analyzed by LC-MS (without derivatization) and GC-FID (with BSTFA/TMCS derivatizations). For sequential extraction, HPLC-UV and BSTFA/TMCS-derivatized GC-FID detection were more responsive to the polar molecules with a rough distribution of 10%, 10%, and 80% of the total signals in hexane, ethyl acetate, and 50% aqueous methanol, respectively...
December 5, 2017: Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences
https://www.readbyqxmd.com/read/29232572/facile-biological-synthetic-strategy-to-morphologically-aligned-ceo2-zro2-core-nanoparticles-using-justicia-adhatoda-extract-and-ionic-liquid-enhancement-of-its-bio-medical-properties
#17
Nithya Pandiyan, Balaji Murugesan, Jegatheeswaran Sonamuthu, Selvam Samayanan, Sundrarajan Mahalingam
In this study, a typical green synthesis route has approached for CeO2/ZrO2 core metal oxide nanoparticles using ionic liquid mediated Justicia adhatoda extract. This synthesis method is carried out at simple room temperature condition to obtain the core metal oxide nanoparticles. XRD, SEM and TEM studies employed to study the crystalline and surface morphological properties under nucleation, growth, and aggregation processes. CeO2/ZrO2 core metal oxides display agglomerated nano stick-like structure with 20-45nm size...
November 28, 2017: Journal of Photochemistry and Photobiology. B, Biology
https://www.readbyqxmd.com/read/29231755/pharmaceutical-aspects-of-silver-nanoparticles
#18
Prateek Mathur, Swati Jha, Suman Ramteke, N K Jain
Silver nanoparticles are particles in the size ranging between 1 and 100 nm. The two major methods used for synthesis of silver nanoparticle are the physical and chemical methods with the disadvantage that they are expensive and can also have toxicity. Biological method is being used as an expedient alternative, as this approach is environment-friendly and less toxic and it includes plant extracts, microorganism, fungi, etc. The major applications of silver nanoparticles in the medical field include diagnostic applications and therapeutic applications, apart from its antimicrobial activity...
December 12, 2017: Artificial Cells, Nanomedicine, and Biotechnology
https://www.readbyqxmd.com/read/29230814/nigella-sativa-l-as-an-alternative-antibiotic-feed-supplement-and-effect-on-growth-performance-in-weanling-pigs
#19
Branko T Petrujkić, Ross C Beier, Haiqi He, Kenneth J Genovese, Christina L Swaggerty, Michael E Hume, Tawni L Crippen, Roger B Harvey, Robin C Anderson, David J Nisbet
BACKGROUND: Nigella sativa L. (NS) is a plant containing bioactive constituents like thymoquinone. Extracts of NS improve performance and reduce enteropathogen colonization in poultry and small ruminants but studies with swine are lacking. In two different studies oral administration of NS extracts at doses equivalent to 0, 1.5 and 4.5 g extract kg-1 diet was assessed on piglet performance and intestinal carriage of wildtype Escherichia coli and Campylobacter, and Salmonella Typhimurium...
December 11, 2017: Journal of the Science of Food and Agriculture
https://www.readbyqxmd.com/read/29230630/phytochemical-study-and-evaluation-of-cytotoxicity-mutagenicity-cell-cycle-kinetics-and-gene-expression-of-bauhinia-holophylla-bong-steud-in-hepg2-cells-in-vitro
#20
Diego Luis Ribeiro, Heloísa Lizotti Cilião, Ana Flávia Leal Specian, Juliana Mara Serpeloni, Marcelo Tempesta De Oliveira, Eliana Aparecida Varanda, Wagner Vilegas, Luiz Leonardo Saldanha, Wilner Martínez-López, Anne Lígia Dokkedal, Ilce Mara Syllos Cólus
Bauhinia holophylla (Bong.) Steud. (Fabaceae) is a plant used in Brazilian folk medicine to treat diabetes and inflammation. This study evaluated the phytochemical properties, cytotoxic, apoptotic, mutagenic/antimutagenic effects and alterations in gene expression (RNAm) in HepG2 cells treated with the B. holophylla extract. The phytochemical profile highlight the presence of flavonoids isorhamentin and quercetin derivates. The MTT assay was used to evaluate the cytotoxicity of different concentrations for different treatment times...
December 11, 2017: Cytotechnology
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