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Spine tumor

Kunal Ajay Shah, Ajay Chimanlal Shah
Spinal Schwannomas are benign nerve sheath tumors and the most common intradural extramedullary tumors of the spine, mainly occurring in the cervical and lumbar region. The location distinct from the spinal canal is very rare. We report a rare case of a 45year old male with Schwannoma in the dorsal paraspinal musculature. Complete surgical excision of the lesion was performed with clear margins and neuropathological analysis revealed a Schwannoma. There has been no recurrence after 6 months.
June 2018: Journal of Clinical Orthopaedics and Trauma
De-Jian Chen, Qi Lai, Jianghao Zhu, Zongmiao Wan, Hucheng Liu, Min Dai, Runsheng Guo, Bin Zhang
RATIONALE: Osteosarcoma is a rare neoplasm in the lumbar spine. Although osteosarcoma can arise in any portion of the skeleton, it very rarely arises in the spinal canal, which accounts for <0.1% of all cases of adult sarcomas. Here, we describe a case of osteosarcoma arising in the L4-5 spinal canal. PATIENT CONCERNS: The present report describes the case of a 55-year-old female patient with osteosarcoma of the L4-5 spinal canal. DIAGNOSES: The patient was initially diagnosed with lumbar spinal stenosis and underwent lumbar fusion at a local hospital...
June 2018: Medicine (Baltimore)
Yibiao Zhou, Bolin Hu, Zhiwei Wu, Hanxiong Cheng, Min Dai, Bin Zhang
RATIONALE: Chordomas are malignant neoplasms derived from incomplete regression of notochordal tissue along the craniococcygeal axis.It is rare for Chordoma arising from the lumbar spine and the traditional long-term prognosis is typically poor. PATIENT CONCERNS: The persistent pain in the left side of the waist about 2 years. DIAGNOSES: Chordoma. INTERVENTIONS: The patient was treated with surgical resection of the total tumor, followed by the spinal internal fixation of L1 to L2 with pedicle screws...
June 2018: Medicine (Baltimore)
Apiruk Sangsin, Hideki Murakami, Takaki Shimizu, Satoshi Kato, Hiroyuki Tsuchiya
Acinic cell carcinoma metastasizing to the spine is extremely rare. The authors present a case of acinic cell carcinoma of the parotid gland with subsequent lung and spinal metastases, treated with en bloc spondylectomy. A 41-year-old man presented with a left parotid mass. After being diagnosed with acinic cell carcinoma, he underwent a total parotidectomy. Imaging studies revealed a metastatic osteoblastic lesion in the T4 vertebral body and multiple lung metastases. Total en bloc spondylectomy and reconstruction with a frozen tumor-bearing bone graft were performed to treat the T4 metastasis...
June 18, 2018: Orthopedics
Bin Liu, Zhenchao Yuan, Chang Yuan Wei
Objective: The incidence rate of thoracic metastasis from breast cancer is increasing. Microwave ablation is one type of clinical therapy used to treat metastatic spine disease, although it can cause protein denaturation and immediate cell death, and coagulative necrosis can occur. Minimally invasive open decompression is associated with lower rates of surgical complications in comparison to traditional open surgery. Therefore, it is an alternative therapeutic option for spinal metastases...
2018: Cancer Management and Research
Kei Ito, Keiji Nihei, Takuya Shimizuguchi, Hiroaki Ogawa, Tomohisa Furuya, Shurei Sugita, Takahiro Hozumi, Keisuke Sasai, Katsuyuki Karasawa
OBJECTIVE This study aimed to clarify the outcomes of postoperative re-irradiation using stereotactic body radiotherapy (SBRT) for metastatic epidural spinal cord compression (MESCC) in the authors' institution and to identify factors correlated with local control. METHODS Cases in which patients with previously irradiated MESCC underwent decompression surgery followed by spine SBRT as re-irradiation between April 2013 and May 2017 were retrospectively reviewed. The surgical procedures were mainly performed by the posterior approach and included decompression and fixation...
June 15, 2018: Journal of Neurosurgery. Spine
Nicolas W Villelli, David M Lewis, Thomas J Leipzig, Andrew J DeNardo, Troy D Payner, Charles G Kulwin
OBJECTIVE Intraoperative angiography can be a valuable tool in the surgical management of vascular disorders in the CNS. This is typically accomplished via femoral artery puncture; however, this can be technically difficult in patients in the prone position. The authors describe the feasibility of intraoperative angiography via the popliteal artery in the prone patient. METHODS Three patients underwent intraoperative spinal angiography in the prone position via vascular access through the popliteal artery. Standard angiography techniques were used, along with ultrasound and a micropuncture needle for initial vascular access...
June 15, 2018: Journal of Neurosurgery. Spine
Gregoire Chick, Jan Victor, Thibault Poujade, Nadine Hollevoet
AIMS:  To identify the frequency of reports of sporadic schwannomatosis, the types of patients affected, and the nerves affected. PATIENTS AND METHODS:  We identified all case reports and case series that reported on patients with sporadic schwannomatosis according to established criteria. RESULTS:  The initial search yielded 1,597 studies, of which 15 were included. A total of 38 of 55 individuals met the inclusion criteria. The mean age of the patients was 48 years; 41% were male...
June 14, 2018: Journal of Neurological Surgery. Part A, Central European Neurosurgery
Julia R Schneider, Kevin Kwan, Kay O Kulason, Lukas J Faltings, Stephanie Colantonio, Scott Safir, Tina Loven, Jian Yi Li, Karen S Black, B Todd Schaeffer, Mark B Eisenberg
Background: Amyloidosis encompasses a group of disorders sharing the common feature of intercellular deposition of amyloid protein by several different pathogenetic mechanisms. Primary solitary amyloidosis, or amyloidoma, is a rare subset of amyloidosis in which amyloid deposition is focal and not secondary to a systemic process or plasma cell dyscrasia. Case Description: This 84-year-old female presented with history of multiple syncopal episodes, dysphagia, and ataxia...
2018: Surgical Neurology International
Meaghan A O'Reilly, Tricia Chinnery, My-Linh Yee, Sheng-Kai Wu, Kullervo Hynynen, Robert S Kerbel, Gregory J Czarnota, Kathleen I Pritchard, Arjun Sahgal
Leptomeningeal metastases (LM) are a serious complication of cancer in the central nervous system (CNS) and are diagnosed in approximately 5% of patients with solid tumors. Effective treatment using systemically administered therapeutics is hindered by the barriers of the CNS. Ultrasound can mediate delivery of drugs through these barriers. The goal of this study was to test the feasibility of using ultrasound-mediated drug delivery to improve the treatment of LM. LM was induced in the spinal cord of athymic rats by injecting HER2-expressing breast cancer cells into the subarachnoid space of the thoracic spine...
June 13, 2018: Scientific Reports
Chih-Chuan Hsieh, Chiao-Zhu Li, Meng-Chi Lin, Yun-Ju Yang, Kun-Ting Hong, Yi-Hsun Chen, Zih-Hsian Syu, Da-Tong Ju
This study aims to compare the effect of Philips' Brilliance 64-slice and 256-slice (multislice) computed tomography on effective doses when changing the operating parameters for simulated examinations of patients' spine tumors, including changes in pitch, tube voltage (kV), and effective tube current-time product (mA s). This study considers the possibility of using other probable operating conditions to reduce patients' effective doses. The absorbed doses to organs and skin are measured by taking data from thermoluminescent dosimeters (GR-200 and GR-200F) in relevant positions on the anthropomorphic Rando phantom...
June 11, 2018: Health Physics
Naohisa Miyakoshi, Daisuke Kudo, Michio Hongo, Yuji Kasukawa, Yoshinori Ishikawa, Yoichi Shimada
BACKGROUND: Safe excision of spinal cord tumors depends on sufficient visualization of the tumor and surrounding structures. In patients with spinal cord tumor adjacent to a stenotic spinal canal, extensive bony decompression proximal and distal to the tumor should be considered for safer excision of the tumor. Extensive wide laminectomy is one choice for such cases, but postoperative problems such as kyphotic deformity remain a concern. CASE PRESENTATION: A 76-year-old man and a 60-year-old woman presented with symptomatic intradural extramedullary spinal cord tumors in the cervical spine...
June 11, 2018: BMC Surgery
Philipp Franck, Jaime L Bernstein, Leslie E Cohen, Roger Härtl, Ali A Baaj, Jason A Spector
OBJECTIVES: Patients with neoplastic disease involving the spine either from primary or metastatic disease present a unique challenge given these patients' frequent poor nutritional status at the time of surgery, the delivery of early post-operative chemotherapy or radiation, and placement of large amounts of hardware and avascular bone graft into a wound bed that is atrophic, previously operated or irradiated. As a result, wound morbidity has traditionally been high in this cohort of patients...
May 29, 2018: Clinical Neurology and Neurosurgery
Ori Barzilai, Ilya Laufer, Adam Robin, Ran Xu, Yoshiya Yamada, Mark H Bilsky
BACKGROUND: Despite major advances in radiation and systemic treatments, surgery remains a critical step in the multidisciplinary treatment of metastatic spinal cord tumors. OBJECTIVE: To describe the indications, rationale, and technique of "hybrid therapy" (separation surgery and concomitant spine stereotactic radiosurgery [SRS]) along with practical nuances. METHODS: Separation surgery describes a posterolateral approach for circumferential epidural decompression and stabilization...
June 8, 2018: Operative Neurosurgery (Hagerstown, Md.)
Marcus Stephens, Arunprasad Gunasekaran, Clay Elswick, Jonathan A Laryea, Thomas Glenn Pait, Noojan Kazemi
Sacral tumors continue to present a significant challenge to the spine surgeon. As new techniques have evolved in recent years, these lesions have become more amenable to aggressive surgical treatment. Although sacral tumors make up only a small minority of spinal tumors, the surgical management is well deserving of special consideration. To ensure a successful outcome - a goal-directed, methodical approach is required. Based on our experience, we highlight three important surgical nuances specifically for the treatment of sacral tumors including preservation and maximization of neurologic function, protection of ventral abdominal and pelvic structures, and lumbo-pelvic fixation...
June 5, 2018: World Neurosurgery
Peng Lin, Nong Lin, Wangsiyuan Teng, Sheng-Dong Wang, Wei-Bo Pan, Xin Huang, Xiao-Bo Yan, Meng Liu, Heng-Yuan Li, Bing-Hao Li, Ling-Ling Sun, Zhan Wang, Xing-Zhi Zhou, Zhao-Ming Ye
OBJECTIVE: To review the clinical details and further treatments for recurrent spinal giant cell tumors (SGCT), and to analyze the risk factors of recurrence and shed new light on the treatment options and prognosis of recurrent SGCT. METHODS: A retrospective analysis of recurrent SGCT between April 2003 and January 2014 was performed. A total of 10 patients comprising 3 men and 7 women with a mean age of 28.9 years (range, 21-40 years) were included in the study...
May 2018: Orthopaedic Surgery
Tero Irmola, Minna K Laitinen, Jyrki Parkkinen, Jacob Engellau, Marko H Neva
PURPOSE: We present a case report that describes neoadjuvant denosumab therapy initiated in a child with a solitary giant cell-rich juvenile xanthogranuloma tumor involving the spine, and review the current literature. METHODS: A giant cell-rich histiocytic lesion involving the 11th thoracic vertebral body was identified in a healthy 5-year-old girl with persistent back and pelvic pain for several months. Imaging examinations and an open biopsy were performed to obtain a definite pathologic diagnosis...
June 6, 2018: European Spine Journal
Sonia Bianchini, Andrea Esposito, Nicola Principi, Susanna Esposito
Background: Spondylodiscitis (SD), the concurrent infection of a vertebral disc and the adjacent vertebral bodies, is a very severe disease that can lead to death or cause spinal deformities, segmental instabilities, and chronic pain, which significantly reduces the quality of life for affected patients. Early diagnosis and treatment are essential in order to reduce the risk of negative outcomes. The two cases of SD that are described in this paper might be useful for informing paediatric approaches to children with SD...
June 7, 2018: International Journal of Environmental Research and Public Health
Simone E Dekker, Chad A Glenn, Thomas A Ostergard, Osmond C Wu, Fernando Alonso, Jonathan A Pace, Brian D Rothstein, Abhishek Ray, Nicholas C Bambakidis
This 3-dimensional operative video illustrates resection of 2 cervical spine schwannomas in a 19-yr-old female with neurofibromatosis type 2. The patient presented with lower extremity hyperreflexity and hypertonicity. Magnetic resonance imaging (MRI) demonstrated 2 contrast-enhancing intradural extramedullary cervical spine lesions causing spinal cord compression at C4 and C5. The patient underwent a posterior cervical laminoplasty with a midline dural opening for tumor resection. Curvilinear spine cord compression is demonstrated in the operative video...
June 5, 2018: Operative Neurosurgery (Hagerstown, Md.)
W Z Pawlak, L Svensson, P F Jensen
Background Symptoms from disseminated cancer can develop very slowly. This could be very difficult to distinguish those symptoms from chronic disabilities and nuisances in patients with chronic non-malignant pain. Objective In this report, the case of a woman with both nonmalignant pain and cancer is presented. Case report A 54 years old woman was referred by a general practitioner to Multidisciplinary Pain Center. The diagnosis was chronic non-malignant neck pain on the basis of degenerative columnar disease...
December 29, 2017: Scandinavian Journal of Pain
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