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https://www.readbyqxmd.com/read/29457442/-development-and-application-of-artificial-vertebral-body
#1
REVIEW
Jian-Tao Liu, Feng Zhang, Zheng-Chao Gao, Bin-Bin Niu, Yu-Huan Li, Xi-Jing He
Artificial vertebral body has achieved good results in treating spinal tumors, tuberculosis, fracture and other diseases. Currently, artificial vertebral body with variety of kinds and pros and cons, is generally divided into two types: fusion type and movable type. The former according to whether the height could be adjusted and strength of self-stability is divided into three types: support-fixed type, adjust-fixed type and self-fixed type. Whether the height of self-fixed type could be adjusted is dependent on structure of collar thread rotation...
December 25, 2017: Zhongguo Gu Shang, China Journal of Orthopaedics and Traumatology
https://www.readbyqxmd.com/read/29456358/surgically-treated-primary-spinal-cord-neoplasms-in-southeastern-nigeria
#2
Mark Chukwunweike Chikani, Okwuoma Okwunodulu, Mathew Mesi, Wilfred C Mezue, Samuel C Ohaegbulam, Chika C Ndubuisi
Background: Primary spinal cord tumors are not as frequently encountered as their cranial counterparts. They could present in such an indolent manner that requires a reasonable index of suspicion for their diagnosis to be considered. Objective: The objective of this study is to analyze the incidence and pattern of primary spinal cord and appendage neoplasms in patients surgically treated in our institution over a decade of practice. Materials and Methods: A retrospective review of clinical, radiological, and histopathology profiles of patients surgically treated for primary spinal cord tumor from 2006 to 2016 was carried out...
January 2018: Journal of Neurosciences in Rural Practice
https://www.readbyqxmd.com/read/29456155/rheumatic-syndromes-and-occult-tumor-10-year-experience-in-a-teaching-hospital
#3
David Castro Corredor, Marco Aurelio Ramírez Huaranga, Ana Isabel Rebollo Giménez, Rocío Arenal López, José Luis Cuadra Díaz
OBJECTIVE: To describe the different clinical characteristics of patients admitted to the Rheumatology Department due to rheumatic manifestations as the first expression of an unknown malignant process. PATIENTS AND METHODS: Retrospective and descriptive observational study involving the review of the medical records of those admitted to rheumatology in the University Hospital of Ciudad Real between January 2007 and August 2017 for initial rheumatic manifestations with a suspicion at discharge of an unknown tumor...
February 15, 2018: Reumatología Clinica
https://www.readbyqxmd.com/read/29455398/mr-imaging-of-neoplastic-and-non-neoplastic-lesions-of-the-brain-and-spine-in-neurofibromatosis-type-i
#4
Ahmed Abdel Khalek Abdel Razek
The aim of this work is to review the MR imaging of neoplastic and non-neoplastic lesions of the brain and spine in neurofibromatosis type I. Neoplastic lesions are optic pathway gliomas, brain stem gliomas, other gliomas of the brain, and peripheral nerve sheath tumors. Structural changes in the brain include unidentified bright objects, macrocephaly, and enlarged corpus callosum. Bony dysplasia changes as sphenoid ridge dysplasia, spinal scalloping, dural ectasia, and meningoceles. Vasculopathy and cortical cerebral and cerebellar malformations of the brain have been reported...
February 17, 2018: Neurological Sciences
https://www.readbyqxmd.com/read/29449506/whole-body-magnetic-resonance-imaging-in-axial-spondyloarthritis-reduction-of-sacroiliac-spinal-and-entheseal-inflammation-in-a-placebo-controlled-trial-of-adalimumab
#5
Simon Krabbe, Mikkel Østergaard, Iris Eshed, Inge J Sørensen, Bente Jensen, Jakob M Møller, Lone Balding, Ole R Madsen, Karsten Asmussen, Grith Eng, Niklas R Jørgensen, Susanne J Pedersen
OBJECTIVE: To investigate whether adalimumab (ADA) reduces whole-body (WB-) magnetic resonance imaging (MRI) indices for inflammation in the entheses, peripheral joints, sacroiliac joints, spine, and the entire body in patients with axial spondyloarthritis (axSpA). METHODS: An investigator-initiated, randomized, placebo-controlled, double-blinded 48-week followup trial included 49 patients with axSpA, who had Bath Ankylosing Spondylitis Disease Activity Index (BASDAI) ≥ 4...
February 15, 2018: Journal of Rheumatology
https://www.readbyqxmd.com/read/29446979/synovial-sarcoma-mimicking-a-thoracic-dumbell-schwannoma-a-case-report
#6
Susanth Subramanian, Gandham Edmond Jonathan, Bimal Patel, Krishna Prabhu
INTRODUCTION: Synovial sarcoma is a rare mesenchymal malignant neoplasm that accounts for less than 10% of soft tissue sarcomas. About 95% of the sarcomas occur in the extremities. Primary synovial sarcomas of the spine are a rare tumor arising from the paravertebral regions, paraspinal muscles or epidural spaces. PURPOSE: To report an atypical radiological presentation of synovial sarcoma of the thoracic spine mimicking a nerve sheath tumor in an elderly adult and describe the management with review of the literature...
February 15, 2018: British Journal of Neurosurgery
https://www.readbyqxmd.com/read/29434866/logistic-regression-analysis-of-risk-factors-for-postoperative-recurrence-of-spinal-tumors-and-analysis-of-prognostic-factors
#7
Shanyong Zhang, Lili Yang, Chuangang Peng, Minfei Wu
The aim of the present study was to investigate the risk factors for postoperative recurrence of spinal tumors by logistic regression analysis and analysis of prognostic factors. In total, 77 male and 48 female patients with spinal tumor were selected in our hospital from January, 2010 to December, 2015 and divided into the benign (n=76) and malignant groups (n=49). All the patients underwent microsurgical resection of spinal tumors and were reviewed regularly 3 months after operation. The McCormick grading system was used to evaluate the postoperative spinal cord function...
February 2018: Oncology Letters
https://www.readbyqxmd.com/read/29433181/craniovertebral-junction-transoral-approach-predictive-factors-of-complications
#8
Aymeric Amelot, Louis-Marie Terrier, Guillaume Lot
BACKGROUND: The transoral approach provides the most direct exposure to extradural lesions of the ventral craniovertebral junction. The morbidity and mortality from this approach greatly limits its use because they are still feared and debated. Using univariable and multivariable logistic regression analyses, this study aims to identify the factors associated with short-term complications in patients undergoing the transoral approach. METHODS: A consecutive cohort analysis of prospectively collected data in several neurosurgery spine departments evaluated 143 consecutive patients who had undergone craniovertebral junction transoral approach surgery...
February 2018: World Neurosurgery
https://www.readbyqxmd.com/read/29429794/treatment-plan-quality-and-delivery-accuracy-assessments-on-3-imrt-delivery-methods-of-stereotactic-body-radiotherapy-for-spine-tumors
#9
Long Huang, Toufik Djemil, Tingliang Zhuang, Martin Andrews, Samuel T Chao, John H Suh, Ping Xia
Stereotactic body radiotherapy (SBRT) for spine tumors has demonstrated clinical effectiveness. The treatment planning and delivery techniques have evolved from dynamic conformal arc therapy, to fixed gantry angle intensity modulated radiotherapy (IMRT), and most recently to volumetric modulated arc therapy (VMAT). A hybrid-arc (HARC) planning and delivery method combining dynamic conformal arc therapy delivery with a number of equally spaced IMRT beams is proposed. In this study we investigated plan quality, delivery accuracy, and efficiency of 3 delivery techniques: IMRT, HARC, and VMAT...
February 8, 2018: Medical Dosimetry: Official Journal of the American Association of Medical Dosimetrists
https://www.readbyqxmd.com/read/29427010/feasibility-of-anterior-screw-fixation-in-children-a-tomographic-study
#10
Lívia Gaspar Fernandes, Alexandre Fogaça Cristante, Raphael Martus Marcon, Tarcísio Eloy Pessoa de Barros Filho, Olavo Biraghi Letaif
PURPOSE: Morphology measures of the odontoid process in children under 12 years old were carried out to demonstrate the viability of anterior internal fixation in this population once their active profile may not be compatible with successful conservative treatment. METHODS: During a 6-month period, 36 tomographic examinations of the cervical spine region that provided visualization of the odontoid process were selected. Group 1 included children between 6 and 9 years of age, and group 2 contained children from 9 to 12 years of age...
February 9, 2018: European Spine Journal
https://www.readbyqxmd.com/read/29423888/posterolateral-cervical-transpedicular-corpectomy-for-the-surgical-management-of-metastatic-tumor
#11
Martin H Pham, Joshua Bakhsheshian
Management of metastatic spinal disease in the upper cervical spine can be particularly challenging. Depending on the level of the lesion and the patient's anatomy, multiple anterior approaches have been described for resection of the cancer, followed by posterior fixation and instrumentation. Although a single-stage posterolateral approach is now well established for thoracic pathology, less is known about the applicability of these principles when applied as an approach to the cervical spine. The authors present here a case using a posterolateral transpedicular approach for corpectomy and graft placement for circumferential reconstruction as a treatment of metastatic disease in the cervical spine to illustrate the feasibility of this technique, especially in the setting where the patient's anatomy or pathology may impede an anterior or combined circumferential approach...
February 9, 2018: European Spine Journal
https://www.readbyqxmd.com/read/29422366/ossified-extradural-en-plaque-meningioma-of-the-cervical-spine
#12
Koichiro Sakamoto, Satoshi Tsutsumi, Senshu Nonaka, Takamoto Suzuki, Hisato Ishii, Masanori Ito, Yukimasa Yasumoto
A 57-year-old woman sustained gradually progressive sensorimotor disturbance in the left upper extremity for one year. Neurological examination found a diminished sensation below the left C7 dermatome and reduced strength in the left interosseous muscles. Computed tomography of the cervical spine revealed a high density mass at C7, in the left dorsal part of the spinal canal. Magnetic resonance imaging found an enhancing, en-plaque tumor at C6-T1, involving a non-enhancing part, and considerable compression of the spinal cord...
February 5, 2018: Journal of Clinical Neuroscience: Official Journal of the Neurosurgical Society of Australasia
https://www.readbyqxmd.com/read/29421450/a-case-of-spinal-osteoblastoma-in-the-elderly-is-it-really-a-young-patient-s-disease
#13
Pasquale Anania, Pietro Fiaschi, Paolo Merciadri, Nataniele Piol, Jean Louis Ravetti, Gianluigi Zona, Pier Filippo Sbaffi
BACKGROUND: Osteoblastoma is a benign bone forming tumor, sometimes locally invasive, that may involve any bone. The highest incidence is between 20 and 30 years of age and there are no cases described in the elderly. METHODS: We report a case of an elderly patient with a lesion in the lumbar spine in which osteoblastoma diagnosis was made. CONCLUSIONS: Osteoblastoma is a rare tumor over 50 years of age but it should be considered in the differential diagnosis of bone lesions of the spine in adulthood and in the elderly, to avoid a delay in the treatment...
February 5, 2018: World Neurosurgery
https://www.readbyqxmd.com/read/29409108/psychometric-evaluation-and-adaptation-of-the-spine-oncology-study-group-outcomes-questionnaire-to-evaluate-health-related-quality-of-life-in-patients-with-spinal-metastases
#14
Anne L Versteeg, Arjun Sahgal, Laurence D Rhines, Daniel M Sciubba, James M Schuster, Michael H Weber, Peter Pal Varga, Stefano Boriani, Chetan Bettegowda, Michael G Fehlings, Michelle J Clarke, Paul M Arnold, Ziya L Gokaslan, Charles G Fisher
BACKGROUND: The Spine Oncology Study Group Outcomes Questionnaire (SOSGOQ) was developed as the first spine oncology-specific health-related quality of life (HRQOL) measure. This study evaluated the psychometric properties and clinical validity of the SOSGOQ in a diverse cohort of patients with spinal metastases. METHODS: An international, multicenter, prospective observational cohort study including patients with spinal metastases who underwent surgery and/or radiotherapy was conducted by the AOSpine Knowledge Forum Tumor...
February 6, 2018: Cancer
https://www.readbyqxmd.com/read/29408781/extradural-petromastoid-calcifying-pseudoneoplasm-of-the-neuraxis-capnon-case-report-and-literature-review
#15
Eric S Nussbaum, Chris Hilton, Archie Defillo, William McDonald, Theodore Passe, Kevin M Kallmes, Leslie A Nussbaum
BACKGROUND: Calcifying pseudoneoplasm of the neuraxis (CAPNON) is a very rare tumor with fewer than 70 cases reported in the literature. In general, this tumor occurs intracranially either within the brain parenchyma or in an extra-axial location, but it has also been described within the spine as an extra-axial lesion. CASE DESCRIPTION: We describe an unusual case of intracranial-extradural CAPNON involving the mastoid region. This may be only the second such case reported in the literature, as one patient with CAPNON has been reported involving the sinonasal region...
January 12, 2018: Clinical Neurology and Neurosurgery
https://www.readbyqxmd.com/read/29405914/wilms-tumor-1b-defines-a-wound-specific-sheath-cell-subpopulation-associated-with-notochord-repair
#16
Juan Carlos Lopez-Baez, Daniel J Simpson, Laura LLeras Forero, Zhiqiang Zeng, Hannah Brunsdon, Angela Salzano, Alessandro Brombin, Cameron Wyatt, Witold Rybski, Leonie F A Huitema, Rodney M Dale, Koichi Kawakami, Christoph Englert, Tamir Chandra, Stefan Schulte-Merker, Nicholas D Hastie, E Elizabeth Patton
Regenerative therapy for degenerative spine disorders requires the identification of cells that can slow down and possibly reverse degenerative processes. Here, we identify an unanticipated wound-specific notochord sheath cell subpopulation that expresses Wilms Tumor (WT) 1b following injury in zebrafish. We show that localized damage leads to Wt1b expression in sheath cells, and that wt1b+ cells migrate into the wound to form a stopper-like structure, likely to maintain structural integrity. Wt1b+ sheath cells are distinct in expressing cartilage and vacuolar genes, and in repressing a Wt1b-p53 transcriptional programme...
February 6, 2018: ELife
https://www.readbyqxmd.com/read/29403254/primary-dorsal-spine-primitive-neuroectodermal-tumor-in-an-adult-patient-case-report-and-literature-review
#17
Satyashiva Munjal, Amit Srivastava, Shivya Tucker, Neha Bakshi, Sunita Bhalla, V S Mehta
Primary spinal primitive neuroectodermal tumor (psPNET) is a rare entity with few cases reported in literature. We report a case of a 50-year-old female who presented to us with paraplegia and was diagnosed with extradural dorsal spine psPNET. The diagnosis was not suspected at presentation or on radiology but was established on histopathological examination. It is important to distinguish it from central nervous system primitive neuroectodermal tumors and from other spinal tumors since it follows a different clinical course and therapeutic outcome...
October 2017: Journal of Craniovertebral Junction and Spine
https://www.readbyqxmd.com/read/29402333/clinical-results-of-multidisciplinary-therapy-including-palliative-posterior-spinal-stabilization-surgery-and-postoperative-adjuvant-therapy-for-metastatic-spinal-tumor
#18
Hiroshi Uei, Yasuaki Tokuhashi, Masafumi Maseda, Masahiro Nakahashi, Hirokatsu Sawada, Enshi Nakayama, Hirotoki Soma
BACKGROUND: Surgeries performed for metastatic spinal tumor are mostly palliative and are controversial for patients with short life expectancy. We investigated whether palliative posterior spinal stabilization surgery with postoperative multidisciplinary therapy results in improvement of life prognosis and activities of daily living (ADL) in patients with metastatic spinal tumor. METHODS: The subjects were 55 patients who underwent palliative posterior-only instrumentation surgery for metastatic spinal tumor at our hospital between 2012 and 2015...
February 5, 2018: Journal of Orthopaedic Surgery and Research
https://www.readbyqxmd.com/read/29399178/g-csf-producing-oral-carcinoma-with-diffuse-uptake-of-fdg-in-the-bone-marrow-a-case-report
#19
Takeshi Kuroshima, Mayumi Wada, Takehiko Sato, Masashi Takano, Shujiroh Makino
A 78-year-old male patient was referred to the Department of Oral Surgery, Hokuto Hospital (Obihiro, Japan) for painless swelling on the left neck and tongue. Histopathological examination of a biopsy specimen resulted in a diagnosis of squamous cell carcinoma of the tongue. Imaging examinations revealed cervical lymph node metastases on both sides, along with diffuse uptake of 18F-fluorodeoxyglucose (FDG) in the bone marrow of the spine and pelvis. Hematologic tests revealed an increased white blood cell (WBC) count and serum concentrations of granulocyte colony stimulating factor (G-CSF)...
January 2018: Oncology Letters
https://www.readbyqxmd.com/read/29393831/a-historical-recount-of-chordoma
#20
Ronald Sahyouni, Khodayar Goshtasbi, Amin Mahmoodi, Jefferson W Chen
Chordoma, a rare bone tumor that occurs along the spine, has led scientists on a fascinating journey of discoveries. In this historical vignette, the authors track these discoveries in diagnosis and treatment, noting events and clinicians that played pivotal roles in our current understanding of chordoma. The study of chordoma begins in 1846 when Rudolf Virchow first observed its occurrence on a dorsum sellae; he coined the term "chordomata" 11 years later. The chordoma's origin was greatly disputed by members of the scientific community...
February 2, 2018: Journal of Neurosurgery. Spine
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