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https://www.readbyqxmd.com/read/29052751/-prevention-of-infections-due-to-musculoskeletal-allografts
#1
REVIEW
A Pruß
Transplantation of musculoskeletal tissues is widely used in the treatment of extensive defects of the musculoskeletal system, especially in orthopedics for exchange of prostheses, surgical interventions on the spine and in traumatology for reconstruction after extensive tumor resections. A danger after transplantation is the potential transmission of clinically relevant pathogens. Tissue banks have therefore established a safety level approach for musculoskeletal tissue transplants, which includes donor selection, laboratory testing, tissue procurement, tissue processing, tissue storage and quality assurance...
October 20, 2017: Der Unfallchirurg
https://www.readbyqxmd.com/read/29048517/vertebral-compression-fracture-after-spine-stereotactic-body-radiation-therapy-a-review-of-the-pathophysiology-and-risk-factors
#2
Salman Faruqi, Chia-Lin Tseng, Cari Whyne, Majed Alghamdi, Jefferson Wilson, Sten Myrehaug, Hany Soliman, Young Lee, Pejman Maralani, Victor Yang, Charles Fisher, Arjun Sahgal
BACKGROUND: Vertebral compression fracture (VCF) is a challenging and not infrequent complication observed following spine stereotactic body radiation therapy (SBRT). OBJECTIVE: To summarize the data from the multiple studies that have been published, addressing the risk and predictive factors for VCF post-SBRT. METHODS: A systematic literature review was conducted. Studies were selected if they specifically addressed risk factors for post-SBRT VCF in their analyses...
October 18, 2017: Neurosurgery
https://www.readbyqxmd.com/read/29044582/provider-views-on-the-management-of-ewing-sarcoma-of-the-spine-and-pelvis
#3
Chong Zhu, Kristofor A Olson, Michael Roth, David S Geller, Richard G Gorlick, Jonathan Gill, Nadia N Laack, R L Randall
BACKGROUND: Curative therapy for ES requires both chemotherapy and local control of primary tumor. There is no universally accepted standard approach to local control modalities. This survey was conducted to determine practice patterns and factors influencing the choice to offer various local control modalities to patients with ES of the spine and pelvis. METHODS: The survey consisted of four scenarios involving a 15-year-old girl who presented with Ewing sarcoma of thoracic vertebra, sacrum, iliac wing, and acetabulum with or without neurologic compromise...
October 16, 2017: Journal of Surgical Oncology
https://www.readbyqxmd.com/read/29038025/assessment-of-the-cervical-spine-denticulate-ligament-using-mri-volumetric-sequence-comparison-between-1-5-tesla-and-3-0-tesla
#4
Rafael Seragioli, Marcelo Novelino Simao, Gustavo Novelino Simao, Carlos Fernando P S Herrero, Marcello H Nogueira-Barbosa
BACKGROUND: Denticulate ligaments (DLs) are pial extensions on each side of the spinal cord, comprising about 20 to 21 pairs of fibrous structures connecting the dura mater to the spinal cord. These ligaments are significant anatomical landmarks in the surgical approach to intradural structures. To our knowledge, there is no previous study on the detection of DLs using MRI. METHODS: After IRB approval, we retrospectively evaluated 116 consecutive MRI scans of the cervical spine, using the volumetric sequence 3D COSMIC, 65 and 51 studies with 1...
October 13, 2017: Journal of Neuroradiology. Journal de Neuroradiologie
https://www.readbyqxmd.com/read/29033574/surgical-site-infections-following-instrumented-stabilization-of-the-spine
#5
Ulrike Dapunt, Caroline Bürkle, Frank Günther, Wojciech Pepke, Stefan Hemmer, Michael Akbar
BACKGROUND: Implant-associated infections are still a feared complication in the field of orthopedics. Bacteria attach to the implant surface and form so-called biofilm colonies that are often difficult to diagnose and treat. Since the majority of studies focus on prosthetic joint infections (PJIs) of the hip and knee, current treatment options (eg, antibiotic prophylaxis) of implant-associated infections have mostly been adapted according to these results. OBJECTIVE: The aim of this study was to evaluate patients with surgical site infections following instrumented stabilization of the spine with regard to detected bacteria species and the course of the disease...
2017: Therapeutics and Clinical Risk Management
https://www.readbyqxmd.com/read/29031873/does-specialty-matter-a-survey-on-176-italian-neurosurgeons-and-orthopaedic-spine-surgeons-confirms-similar-competency-for-common-spinal-conditions-and-supports-multidisciplinary-teams-in-comprehensive-and-complex-spinal-care
#6
Matteo Pejrona, Gabriele Ristori, Jorge Hugo Villafañe, Fabrizio Ernesto Pregliasco, Pedro Berjano
BACKGROUND CONTEXT: Spine surgery is a multi-faceted sub-speciality requiring a breadth of knowledge and skill from different branches of medicine for the treatment of pathologies varying from degenerative to deformity, oncological, and trauma. PURPOSE: The aim of the study was to investigate the self-perceived competency of spine surgeons in relation to different types of spinal procedures. STUDY DESIGN/SETTING: Survey study. METHODS: We conducted a survey on 176 surgeons (Orthopaedic surgeons and Neurosurgeons)...
October 11, 2017: Spine Journal: Official Journal of the North American Spine Society
https://www.readbyqxmd.com/read/29030654/predictive-and-prognostic-value-of-tumor-volume-and-its-changes-during-radical-radiotherapy-of-stage%C3%A2-iii-non-small-cell-lung-cancer-a%C3%A2-systematic-review
#7
Lukas Käsmann, Maximilian Niyazi, Oliver Blanck, Christian Baues, René Baumann, Sophie Dobiasch, Chukwuka Eze, Daniel Fleischmann, Tobias Gauer, Frank A Giordano, Yvonne Goy, Jan Hausmann, Christoph Henkenberens, David Kaul, Lisa Klook, David Krug, Matthias Mäurer, Cédric M Panje, Johannes Rosenbrock, Lisa Sautter, Daniela Schmitt, Christoph Süß, Alexander H Thieme, Maike Trommer-Nestler, Sonia Ziegler, Nadja Ebert, Daniel Medenwald, Christian Ostheimer
PURPOSE: Lung cancer remains the leading cause of cancer-related mortality worldwide. Stage III non-small cell lung cancer (NSCLC) includes heterogeneous presentation of the disease including lymph node involvement and large tumour volumes with infiltration of the mediastinum, heart or spine. In the treatment of stage III NSCLC an interdisciplinary approach including radiotherapy is considered standard of care with acceptable toxicity and improved clinical outcome concerning local control...
October 13, 2017: Strahlentherapie und Onkologie: Organ der Deutschen Röntgengesellschaft ... [et Al]
https://www.readbyqxmd.com/read/29029886/heterogeneity-in-treatment-response-of-spine-metastases-to-spine-stereotactic-radiosurgery-within-radiosensitive-subtypes
#8
Vincent Bernard, Andrew J Bishop, Pamela K Allen, Behrang Amini, Xin A Wang, Jing Li, Claudio E Tatsui, Laurence D Rhines, Paul D Brown, Amol J Ghia
PURPOSE: To characterize outcomes of metastatic colorectal and non-small cell lung cancer (NSCLC) histologies, compared with other radiosensitive histologies, treated with spine stereotactic radiosurgery with regard to local control, overall survival, and predictors of response. METHODS AND MATERIALS: A total of 127 patients with 148 spine stereotactic radiosurgery-treated metastatic lesions at our institution between 2003 and 2013 were reviewed. We assessed clinical endpoints in relation to histologic type, including local control (LC) and overall survival (OS), using univariate and multivariate analyses...
September 1, 2017: International Journal of Radiation Oncology, Biology, Physics
https://www.readbyqxmd.com/read/29028760/the-impact-of-metastatic-spinal-tumor-location-on-30-day-perioperative-mortality-and-morbidity-after-surgical-decompression
#9
Awais K Hussain, Khushdeep S Vig, Zoe B Cheung, Kevin Phan, Mauricio C Lima, Jun S Kim, Deepak A Kaji, Varun Arvind, Samuel Kang-Wook Cho
STUDY DESIGN: A retrospective cohort study from 2011 to 2014 was performed using the American College of Surgeons National Surgical Quality Improvement Program (ACS-NSQIP) database. OBJECTIVE: The purpose of this study was to assess the impact of tumor location in the cervical, thoracic, or lumbosacral spine on 30-day perioperative mortality and morbidity after surgical decompression of metastatic extradural spinal tumors. SUMMARY OF BACKGROUND DATA: Operative treatment of metastatic spinal tumors involves extensive procedures that are associated with significant complication rates and healthcare costs...
October 12, 2017: Spine
https://www.readbyqxmd.com/read/29027893/hospital-acquired-conditions-predictors-and-implications-for-outcomes-following-spine-tumor-resection
#10
Nikita Lakomkin, Constantinos G Hadjipanayis
OBJECTIVE Hospital-acquired conditions (HACs) significantly compromise patient safety, and have been identified by the Centers for Medicare and Medicaid Services as events that will be associated with penalties for surgeons. The mitigation of HACs must be an important consideration during the postoperative management of patients undergoing spine tumor resection. The purpose of this study was to identify the risk factors for HACs and to characterize the relationship between HACs and other postoperative adverse events following spine tumor resection...
October 13, 2017: Journal of Neurosurgery. Spine
https://www.readbyqxmd.com/read/29021669/is-there-a-correlation-between-the-spinal-instability-neoplastic-score-and-mechanical-pain-in-patients-with-metastatic-spinal-cord-compression-a-prospective-cohort-study
#11
Rodrigo Ac Cavalcante, Yvens B Fernandes, Romulo Al Marques, Vinícius G Santos, Edésio Martins, Vladimir A Zaccariotti, João B Arruda, Claúdio E Tatsui, Andrei F Joaquim
INTRODUCTION: The decision for selecting patients for surgical treatment of metastatic spinal cord compression (MSCC) is challenging even for experienced surgeons. Recently, the spinal instability neoplastic score (SINS) has been proposed to help surgeons in the evaluation of spinal stability in the setting of spinal metastases. This study aimed to evaluate the correlation between SINS and preoperative visual analog scale (VAS), as well as the pre- and post-operative association of the VAS and neurological function...
July 2017: Journal of Craniovertebral Junction and Spine
https://www.readbyqxmd.com/read/29018653/chiari-type-1-malformation-induced-intracranial-hypertension-with-diffuse-brain-edema-treated-with-foramen-magnum-decompression-a-case-report
#12
Toshiki Fukuoka, Yusuke Nishimura, Masahito Hara, Shoichi Haimoto, Kaoru Eguchi, Satoshi Yoshikawa, Toshihiko Wakabayashi, Howard J Ginsberg
Chiari type 1 malformation (CM1) rarely causes papilloedema, which is indicative of high intracranial pressure with or without ventricular dilatation. Furthermore, concomitant brain parenchymal abnormalities have not been reported to date. In this paper, the authors report on a young woman of CM1-induced intracranial hypertension (ICH) with diffuse brain edema with a focus on venous sinus assessment, and discuss the surgical strategy. A 24-year-old woman presented to Nagoya University Hospital complaining of 4-year history of severe occipital headache and blurry vision with slowly progressive worsening...
October 2017: NMC Case Rep J
https://www.readbyqxmd.com/read/29017310/angiolipoma-on-the-lumbar-spine
#13
Hee Il Kang, Tae Wan Kim, Eun Ju Kim, Kwan Ho Park
Angiolipomas are composed of mature adipose tissue and blood vessels. Spinal angiolipomas are rare benign tumors with a good prognosis, and most symptoms are due to progressive compression of the spinal cord and root. The treatment of choice is total resection without any additional therapy. We report a case of an epidural angiolipoma on the lumbar spine in a 69-year-old man with weakness of the lower extremities. Lumbar magnetic resonance images revealed a well-enhanced epidural mass. He underwent laminectomy, and the tumor was completely removed...
September 2017: Korean Journal of Spine
https://www.readbyqxmd.com/read/29017309/langerhans-cell-histiocytosis-of-the-thoracic-spine-in-an-adult
#14
Myeong Cheol Kim, Sun Hee Sung, Yongjae Cho
We report a case of a 45-year-old man with a complaint of both leg weakness and hypoesthesia. Radiological evaluation revealed an osteolytic lesion of the ninth thoracic vertebra. The patient underwent posterior corpectomy with total excision of the tumor, mesh cage insertion with posterior screw fixation and subsequent radiotherapy. Histology confirmed the diagnosis of Langerhans cell histiocytosis (LCH). This case report presents the diagnostic work-up, histopathological evaluation, and the treatment procedures of rare LCH in the thoracic spine...
September 2017: Korean Journal of Spine
https://www.readbyqxmd.com/read/29017306/solitary-osteochondroma-presenting-as-a-dumbbell-tumor-compressing-the-cervical-spinal-cord
#15
Ju Hyung Lee, Sung Han Oh, Pyung Goo Cho, Eun Mi Han, Je Beom Hong
We report a case of a solitary osteochondroma as a dumbbell tumor compressing the spinal cord and its surgical strategy. The patient is a 16-year-old female with longstanding posterior neck pain and left arm abduction weakness. She was examined by plain X-ray, three-dimensional-computed tomography, magnetic resonance imaging, and vertebral angiography. The analyses indicated a calcified extradural mass compressing the cord in the C3-4 portion extending into the neural and vertebral foramen with eroded vertebral body...
September 2017: Korean Journal of Spine
https://www.readbyqxmd.com/read/29016429/is-routine-spine-mri-necessary-in-skeletally-immature-patients-with-mhe-identifying-patients-at-risk-for-spinal-osteochondromas
#16
Taylor J Jackson, Apurva S Shah, Alexandre Arkader
BACKGROUND: Multiple hereditary exostoses (MHE) is an autosomal dominant condition leading to development of osteochondromas throughout the body. Although long bones are most often affected, spine involvement may occur and usually requires advanced imaging for diagnosis. However, the high cost of detection, infrequent occurrence, and very low likelihood of spinal cord compression and neurological injury, create a management conundrum. The purpose of our investigation is to identify patients at greatest risk for spinal lesions and refine indications for advanced imaging...
October 9, 2017: Journal of Pediatric Orthopedics
https://www.readbyqxmd.com/read/28993889/recurrent-primary-osseous-hemangiopericytoma-in-the-thoracic-spine-a-case-report-and-literature-review
#17
Takahiro Onoki, Haruo Kanno, Toshimi Aizawa, Ko Hashimoto, Eiji Itoi, Hiroshi Ozawa
PURPOSE: Primary osseous hemangiopericytoma (HPC) of the spine is exceedingly rare. HPC has malignant potential and has the capacity for metastasis and local recurrence. We herein present the first case of recurrent primary osseous HPC in the thoracic spine that was successfully treated by total spondylectomy at three vertebral levels and spinal reconstruction. METHODS: We performed a two-stage operation for recurrent HPC using anterior and posterior approaches at the T5-T7 vertebrae...
October 9, 2017: European Spine Journal
https://www.readbyqxmd.com/read/28992848/the-first-report-of-human-primary-thoracic-spine-mast-cell-sarcoma-a-case-report
#18
Ali C Ravanpay, Jonathan R Fromm, Kerstin L Edlefsen, Paul Martin, Randal Chesnut
In this report, we present a 53-year-old woman with primary mast cell sarcoma of the thoracic spine vertebrae. Mast cell sarcoma is an aggressive and rare cancer. To date, no cases of primary mast cell sarcoma have been reported in the spinal vertebrae. The patient initially presented with a 1-month history of pelvic and abdominal pain. Inconclusive gynecological evaluation resulted in a CT of the abdomen and pelvis, demonstrating a destructive lesion centered at the 11th thoracic vertebral body. The patient underwent a two-stage spine operation for T11 corpectomy and T7-L3 posterior spinal fusion...
October 10, 2017: Clinical Neuropathology
https://www.readbyqxmd.com/read/28990647/-medullar-thoracic-compression-by-tophaceous-gout-presentation-of-a-case-and-review-of-the-literature
#19
(no author information available yet)
INTRODUCTION: Spine involvement in gout is an extremely uncommon complication. Dorsalgia and quadriplegia are some manifestations that may occur, although these symptoms are seen more frequently in other more prevalent pathologies, such as spinal tumors. CASE REPORT: We present an unusual case of thoracic spinal cord compression at T10-T11 level caused by the extradural deposit of tophaceous material in a 52-year-old woman with uncontrolled chronic tophaceous gout...
October 16, 2017: Revista de Neurologia
https://www.readbyqxmd.com/read/28987196/overview-of-neuroradiology
#20
Elna-Marie Larsson, Johan Wikström
Neuroradiology with computed tomography (CT) and magnetic resonance imaging (MRI) is essential for the initial evaluation of patients with a clinical suspicion of brain and spine disorders. Morphologic imaging is required to obtain a probable diagnosis to support the treatment decisions in pre- and perinatal disorders, vascular diseases, traumatic injuries, metabolic disorders, epilepsy, infection/inflammation, neurodegenerative disorders, degenerative spinal disease, and tumors of the central nervous system...
2017: Handbook of Clinical Neurology
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