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https://www.readbyqxmd.com/read/29682030/maximum-surgical-blood-order-schedule-for-elective-neurosurgery-in-a-university-teaching-hospital-in-northern-thailand
#1
Ananchanok Saringcarinkul, Siriwan Chuasuwan
Context: Preoperative blood bank testing should optimize the trade-off between intraoperative transfusion delay and blood wastage. Aims: This study aims to develop a maximal surgical blood order schedule (MSBOS) for elective neurosurgery. Settings and Design: Prospective data in University Teaching Hospital, Northern Thailand. Subjects and Methods: Blood transfusion data were collected on all adult patients satisfying inclusion/exclusion criteria in 2015...
April 2018: Asian Journal of Neurosurgery
https://www.readbyqxmd.com/read/29681020/risk-factors-for-metastasis-at-presentation-with-conventional-chondrosarcoma-a-population-based-study
#2
Kehan Song, Xiao Shi, Xin Liang, Hongli Wang, Fei Zou, Feizhou Lu, Xiaosheng Ma, Jianyuan Jiang
PURPOSE: The aim of the study was to investigate risk factors for metastasis at diagnosis. METHODS: We collected patients diagnosed with conventional chondrosarcoma between 1983 and 2014 from the Surveillance, Epidemiology, and End Results (SEER) database. Each patient was classified as having metastatic or localized disease. Univariate and multivariate logistic regression analyses were applied to determine which characteristics were risk factors for metastasis at diagnosis...
April 21, 2018: International Orthopaedics
https://www.readbyqxmd.com/read/29680256/dose-sculpting-intensity-modulated-radiation-therapy-for-vertebral-body-sparing-in-children-with-neuroblastoma
#3
Lydia W Ng, Kenneth K Wong, Chia-Ling Ally Wu, Richard Sposto, Arthur J Olch
PURPOSE: To assess the effect of dose sculpting intensity modulated radiation therapy on vertebral body growth in children with neuroblastoma. METHODS AND MATERIALS: From 2000 to 2011, 88 children with neuroblastoma underwent radiation at the authors' institution. Children with paravertebral tumors with at least 3 years of evaluable posttreatment imaging were included, and children who underwent spine reirradiation before follow-up were excluded. If vertebral bodies could not be spared, these "target" vertebral bodies were treated to at least 18 Gy...
February 15, 2018: International Journal of Radiation Oncology, Biology, Physics
https://www.readbyqxmd.com/read/29678526/long-term-outcomes-after-stereotactic-radiosurgery-for-spine-metastases-radiation-dose-response-for-late-toxicity
#4
Diane C Ling, John C Flickinger, Steven A Burton, Dwight E Heron, Annette E Quinn, Ghassan K Bejjani, Johnathan A Engh, Peter C Gerszten, Nduka M Amankulor, John A Vargo
PURPOSE: To document the 5- and 10-year rates of late toxicity and vertebral compression fracture (VCF) in long-term survivors after stereotactic radiosurgery for spine metastases. METHODS AND MATERIALS: A retrospective review was performed on 562 patients treated with SRS for spine metastases between April 2001 and July 2011. Selecting those with at least 5-year survival after SRS, included were 43 patients who collectively underwent 84 treatments at 54 spine sites...
March 6, 2018: International Journal of Radiation Oncology, Biology, Physics
https://www.readbyqxmd.com/read/29678187/an-unexpected-cause-of-sacroiliitis-in-a-patient-with-gout-and-chronic-psoriasis-with-inflammatory-arthritis-a-case-report
#5
Safi Alqatari, Roberta Visevic, Nina Marshall, John Ryan, Grainne Murphy
BACKGROUND: Inflammatory back pain is a condition characterized by inflammation of the sacroiliac joints and lower spine. It is frequently seen in patients with spondyloarthropathies like ankylosing spondylitis, psoriatic arthritis, enteropathic arthritis and reactive arthritis. Inflammatory back pain can be caused by many other conditions like infection and crystal deposition such as gout. In this case, it is difficult to specifically identify gout as a cause by ordinary imaging like magnetic resonance imaging (MRI) or ultrasound...
April 20, 2018: BMC Musculoskeletal Disorders
https://www.readbyqxmd.com/read/29676368/clear-cell-sarcoma-arising-from-paraspinal-ligament-of-thoracic-spine-report-of-an-unusual-case
#6
Ranjan Agrawal, Prabal Deb, Jagdamba Sharan, Parbodh Kumar
Clear cell sarcoma (CCS) is an unusual but aggressive soft-tissue tumor with an incidence of <1% of all soft-tissue sarcomas. It was previously termed "malignant melanoma of soft parts" due to its resemblance clinically and morphologically. Normally CCS is seen in patients aged 20-40 years. A rare case of CCS of paraspinal ligament in a 5-year-old boy is being reported. Histopathology and immunohistochemistry markers confirmed the diagnosis. The present case is unique since the entity itself is rare and also due to its occurrence in a child...
April 2018: Indian Journal of Pathology & Microbiology
https://www.readbyqxmd.com/read/29670012/percutaneous-imaging-guided-biopsy-of-bone-metastases
#7
REVIEW
Dimitrios Filippiadis, Argyro Mazioti, Alexios Kelekis
Approximately 70% of cancer patients will eventually develop bone metastases. Spine, due to the abundance of red marrow in the vertebral bodies and the communication of deep thoracic-pelvic veins with valve-less vertebral venous plexuses, is the most common site of osseous metastatic disease. Open biopsies run the risk of destabilizing an already diseased spinal or peripheral skeleton segment. Percutaneous biopsies obviate such issues and provide immediate confirmation of correct needle location in the area of interest...
April 18, 2018: Diagnostics
https://www.readbyqxmd.com/read/29668630/thoracolumbar-spinal-neurenteric-cyst-with-tethered-cord-syndrome-and-extreme-cervical-lordosis-in-a-child-a-case-report-and-literature-review
#8
Zhi Gang Lan, Seidu A Richard, Chuanfen Lei, Siqing Huang
RATIONALE: Neurenteric cysts, are rare benign tumors of the central nervous system that are mostly located in the spinal cord and predominantly seen in male children although adult form of the disorder also occurs. The etiology and treatment of this disorder is still a matter of debate. Our case further throws more light on the pathogenesis and treatment of this disorder. PATIENT CONCERNS: A 4-year-old boy presented with 5-month history of cervical lordosis and bilateral lower extremity pain that progressed to his abdomen and upper body...
April 2018: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29666038/correlation-of-serum-ccl3-mip-1%C3%AE-levels-with-disease-severity-in-postmenopausal-osteoporotic-females
#9
Hui Wan, Tie-Yong Qian, Xiao-Jing Hu, Ci-You Huang, Wei-Feng Yao
BACKGROUND: The pro-inflammatory protein chemokine cytokine ligand 3 is well-established as a vital regulator of bone resorption and osteoclasts stimulation. AIMS: We sought to investigate if serum chemokine cytokine ligand 3 levels correlated with disease severity in postmenopausal osteoporosis females. STUDY DESIGN: Cross-sectional Study. METHODS: 82 postmenopausal osteoporotic females, 76 postmenopausal non-osteoporotic women and 80 healthy female at childbearing age were recruited...
April 15, 2018: Balkan Medical Journal
https://www.readbyqxmd.com/read/29664878/c2-translaminar-screw-fixation-in-children
#10
Brian W Yang, Michael P Glotzbecker, Michael Troy, Mark R Proctor, Michael T Hresko, Daniel J Hedequist
BACKGROUND: Axis (C2) screw fixation has been shown to be effective in treating disorders that necessitate cervical stabilization. Although translaminar C2 screws have demonstrated clinical efficacy in adults, this technique has not yet been thoroughly investigated in children. This study describes the indications, technique, and results of translaminar C2 screw fixation in a case series of pediatric cervical spine disorders. METHODS: We searched the orthopaedic database at our institution for patients who had undergone a cervical spinal fusion that encompassed C2 between 2007 and 2017...
April 16, 2018: Journal of Pediatric Orthopedics
https://www.readbyqxmd.com/read/29663145/successful-treatment-of-a-diffuse-type-tenosynovial-giant-cell-tumor-in-the-thoracic-spine-mimicking-spinal-metastasis-by-frozen-recapping-laminoplasty-in-a-patient-with-thyroid-cancer
#11
REVIEW
Noritaka Yonezawa, Hideki Murakami, Satoshi Kato, Hiroyuki Hayashi, Hiroyuki Tsuchiya
PURPOSE: Tenosynovial giant cell tumor of the diffuse type (TGCT-D) involving the spine is rare. Its differential diagnosis includes metastatic disease; however, there have been few reports of spinal TGCT-D mimicking spinal metastasis in patients with a history of malignancy. METHODS: We report on a 35-year-old woman with a history of papillary thyroid cancer who was diagnosed with TGCT-D of the thoracic spine mimicking spinal metastasis. Preoperative computed tomography (CT) revealed a 1...
April 16, 2018: European Spine Journal
https://www.readbyqxmd.com/read/29661205/comparison-between-minimally-invasive-spine-stabilization-with-and-without-posterior-decompression-for-the-management-of-spinal-metastases-a-retrospective-cohort-study
#12
Hiroshi Uei, Yasuaki Tokuhashi, Masafumi Maseda, Masahiro Nakahashi, Hirokatsu Sawada, Enshi Nakayama, Hirotoki Soma
BACKGROUND: Posterior decompression and stabilization plays significant roles in palliative surgery for metastatic spinal tumor. However, the indication for addition of posterior decompression have not been examined. The purpose of this study was to investigate a retrospective cohort of outcomes of metastatic spinal tumor treated with minimally invasive spine stabilization (MISt) with or without posterior decompression. METHODS: The subjects were 40 patients who underwent MISt using percutaneous pedicle screws for metastatic spinal tumor, including 20 patients treated with stabilization alone (group A) and 20 patients with added posterior decompression (group B)...
April 16, 2018: Journal of Orthopaedic Surgery and Research
https://www.readbyqxmd.com/read/29657891/stereotactic-radiosurgery-for-primary-tumors-of-the-spine-and-spinal-cord-%C3%A2
#13
Erinma Elibe, David Boyce-Fappiano, Samuel Ryu, M Salim Siddiqui, Ian Lee, Jack Rock, Farzan Siddiqui
Purpose: The purpose of this study was to evaluate the role of stereotactic radiosurgery in the treatment of primary tumors of the spine and spinal cord. Methods: An Institutional Review Board approved retrospective analysis of 30 patients with primary spine tumors treated at a single institution was performed. Post-treatment pain, neurological, and radiographic responses were the endpoints. Results: Nine patients were treated for benign tumors, and 21 patients were treated for malignant tumors...
2018: Journal of Radiosurgery and SBRT
https://www.readbyqxmd.com/read/29657890/pain-flare-after-stereotactic-radiosurgery-for-spine-metastases
#14
Ehsan H Balagamwala, Mihir Naik, Chandana A Reddy, Lilyana Angelov, John H Suh, Toufik Djemil, Anthony Magnelli, Samuel T Chao
Purpose: Understanding of pain flare (PF) following spine stereotactic radiosurgery (sSRS) is lacking. This study sought to determine the incidence and risk factors associated with PF following single fraction sSRS. Materials/methods: An IRB-approved database was compiled to include patients who underwent sSRS. Patient and disease characteristics as well as treatment and dosimetric details were collected retrospectively. Pain relief post-sSRS was prospectively collected using the Brief Pain Inventory (BPI)...
2018: Journal of Radiosurgery and SBRT
https://www.readbyqxmd.com/read/29656619/impact-of-resident-involvement-in-neurosurgery-an-american-college-of-surgeons-national-surgical-quality-improvement-program-database-analysis-of-33-977-patients
#15
Andreea Seicean, Prateek Kumar, Sinziana Seicean, Duncan Neuhauser, Warren R Selman, Nicholas C Bambakidis
OBJECTIVE: There is conflicting and limited literature on the effect of intraoperative resident involvement on surgical outcomes. Our study assessed effects of resident involvement on outcomes in patients undergoing neurosurgery. METHODS: We identified 33,977 adult neurosurgical cases from 374 hospitals in the 2006-2012 National Surgical Quality Improvement Program, a prospectively collected national database with established reproducibility and validity. Outcomes were compared according to resident involvement before and after 1:1 matching on procedure and perioperative risk factors...
March 2018: Neurospine
https://www.readbyqxmd.com/read/29656173/factors-associated-with-extension-of-the-scheduled-time-for-spine-surgery
#16
Kazuyoshi Kobayashi, Kei Ando, Kenyu Ito, Mikito Tsushima, Masayoshi Morozumi, Satoshi Tanaka, Masaaki Machino, Kyotaro Ota, Naoki Ishiguro, Shiro Imagama
OBJECTIVES: Adherence to scheduled times in surgery is important in hospital management. However, sudden surgical changes or unexpected intraoperative problems may lead to prolongation of operative times. The purpose of this study was to investigate operative times in spinal surgery and to identify causes of delays during surgery. PATIENTS AND METHODS: A retrospective review of 488 cases of spinal surgery was performed to investigate operations prolonged for >2 h and to identify factors associated with prolongation...
April 3, 2018: Clinical Neurology and Neurosurgery
https://www.readbyqxmd.com/read/29652780/implication-of-biomarker-mutations-for-predicting-survival-in-patients-with-metastatic-lung-cancer-to-the-spine
#17
Bryan D Choi, Ganesh M Shankar, Ahilan Sivaganesan, Laura A Van Beaver, Kevin Oh, John H Shin
STUDY DESIGN: A retrospective cohort study. OBJECTIVE: We performed a retrospective study of patients treated at our institution over the last 7 years to ascertain whether gene expression signatures in patients with advanced metastatic disease are associated with survival, when the disease has progressed to the spine. SUMMARY OF BACKGROUND DATA: Spinal metastases are a major cause of morbidity in patients with cancer. Molecular profiling strategies to characterize lung cancer have identified several genetic biomarkers that may lead to more effective prognostication...
April 12, 2018: Spine
https://www.readbyqxmd.com/read/29650783/percutaneous-ct-guided-biopsies-of-the-cervical-spine-technique-histopathologic-and-microbiologic-yield-and-safety-at-a-single-academic-institution
#18
E L Wiesner, T J Hillen, J Long, J W Jennings
BACKGROUND AND PURPOSE: Cervical spine biopsies can be challenging due to the anatomy and the adjacent critical structures. Percutaneous image-guided biopsies can obviate the need for an open biopsy, however there have been few studies looking at the approaches, safety, and efficacy of percutaneous cervical spine biopsies. This retrospective study evaluated technical considerations, histopathologic and microbiologic yield, and safety in CT-guided cervical bone biopsies. MATERIALS AND METHODS: A retrospective review of cervical bone and/or bone/disc biopsies performed from January 2010 to January 2017 was included in this study...
April 12, 2018: AJNR. American Journal of Neuroradiology
https://www.readbyqxmd.com/read/29649676/intradural-spinal-tumors-10-years-surgical-experience-in-a-single-institution
#19
Pablo David Guerrero-Suarez, Ernesto Magdaleno-Estrella, Paola Guerrero-López, Arturo Isaac Vargas-Figueroa, Jaime Jesús Martínez-Anda
OBJECTIVES: The aim of the study is to present the therapeutic results of intradural tumor management over a 10 years period in a single institution. PATIENTS AND METHODS: The study consists in a prospective case series of patients treated at the neurosurgery service of the Social Security Institute of Mexico State and Provinces (ISSSEMYM), between January 2006 and December 2016. All patients were provided with information about the procedure and signed informed consent and institutional board approved files review for this study...
March 10, 2018: Clinical Neurology and Neurosurgery
https://www.readbyqxmd.com/read/29649092/ascorbic-acid-attenuates-multifidus-muscles-injury-and-atrophy-after-posterior-lumbar-spine-surgery-by-suppressing-inflammation-and-oxidative-stress-in-a-rat-model
#20
Pan Tang, Yu Gu, Jia-Ming Gu, Zi-Ang Xie, Jia-Qi Xu, Xiang-De Zhao, Kang-Mao Huang, Ji-Ying Wang, Xue-Sheng Jiang, Shun-Wu Fan, Zhi-Jun Hu
STUDY DESIGN: A rat model of multifidus muscles injury and atrophy after posterior lumbar spine surgery. OBJECTIVE: We determined the effect of ascorbic acid (AA) on the postoperative multifidus muscles in rat model. SUMMARY OF BACKGROUND DATA: Previous studies show oxidative stress and inflammation are two main molecular mechanisms in multifidus muscle injury and atrophy after posterior lumbar surgery. AA may have a protective effect in postoperative multifidus muscles...
April 11, 2018: Spine
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