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Elderly and sleep apnea

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https://www.readbyqxmd.com/read/28044184/-outcome-predictors-for-copd-patients-hospitalized-for-acute-exacerbation
#1
M Spielmanns, F Axer, C Nell, A R Koczulla, T Boeselt, F Magnet, J H Storre, W Windisch
BACKGROUND: Prognostic factors for clinical failure of acute exacerbation in patients with COPD (AECOPD) are of special importance in order to choose an adequate therapy and resources during inpatient treatment. Our database was analyzed to identify predictors for a negative outcome. MATERIALS AND METHODS: In a retrospective analysis medical records of 616 patients (299 women; 317 men) hospitalized for AECOPD between January 2011 and January 2016 were analyzed in order to evaluate demographic and clinical parameters leading to adverse events...
January 2, 2017: Medizinische Klinik, Intensivmedizin und Notfallmedizin
https://www.readbyqxmd.com/read/28039650/is-bariatric-surgery-safe-in-the-elderly-population
#2
Federico Perez Quirante, Lisandro Montorfano, Rajmohan Rammohan, Nisha Dhanabalsamy, Aaron Lee, Samuel Szomstein, Emanuele Lo Menzo, Raul J Rosenthal
BACKGROUND: Bariatric surgery has proven to be the most effective treatment for morbid obesity in all age groups and is considered superior to medical treatment. The aim of our study was to report the outcomes of bariatric surgery in patients over 65 years of age at our institution. METHODS: A retrospective review of a prospectively collected database was conducted of all patients > 65 years who underwent a bariatric procedure between 2005 and 2015 at our institution...
December 30, 2016: Surgical Endoscopy
https://www.readbyqxmd.com/read/27976622/exploration-of-sleep-disorders-in-the-elderly-which-particularities
#3
Vi-Huong Nguyen-Michel, Marie-Françoise Vecchierini
There are many reasons to take into consideration the sleep disorders in the elderly. The sleep quality degrades with age and is strongly affected by medical conditions, intrinsic sleep disorders, or by a combination of these factors. Other age-related conditions such as severe dementia, dependence or living in institution worsen sleep disturbances in older people. When living alone elderly people, being cognitively impaired and medically disabled, may not be able to complain about sleep problems. Sleep disorders are thus underdiagnosed, unmarked, and insufficiently investigated in the elderly...
December 1, 2016: Gériatrie et Psychologie Neuropsychiatrie du Vieillissement
https://www.readbyqxmd.com/read/27972297/economic-benefits-of-cpap-treatment-for-obstructive-sleep-apnea-in-the-elderly
#4
S S Park, J Menzin
No abstract text is available yet for this article.
November 2016: Value in Health: the Journal of the International Society for Pharmacoeconomics and Outcomes Research
https://www.readbyqxmd.com/read/27970449/excess-costs-associated-with-obstructive-sleep-apnea-in-the-elderly
#5
J Menzin, S S Park
No abstract text is available yet for this article.
November 2016: Value in Health: the Journal of the International Society for Pharmacoeconomics and Outcomes Research
https://www.readbyqxmd.com/read/27938920/impact-of-different-hypopnea-definitions-on-obstructive-sleep-apnea-severity-and-cardiovascular-mortality-risk-in-women-and-elderly-individuals
#6
Francisco Campos-Rodriguez, Miguel A Martínez-García, Nuria Reyes-Nuñez, Maria J Selma-Ferrer, Naresh M Punjabi, Ramon Farre
OBJECTIVE: To assess the impact of three hypopnea definitions on the severity classification of obstructive sleep apnea (OSA) and its association with cardiovascular mortality risk in women and elderly individuals. METHODS: We analyzed two Spanish clinical cohorts (1116 women and 939 elderly individuals) who were studied for suspicion of OSA between 1998 and 2007. A calibration model was used to apply different definitions of hypopnea to our two cohorts. Hypopnea was defined as a 30-90% reduction in oronasal flow for ≥10 s followed by (1) ≥4% fall in oxyhemoglobin saturation-AHI4%; (2) ≥3% fall in oxyhemoglobin saturation-AHI3%; or (3) ≥3% fall in oxyhemoglobin saturation or an event-related arousal-AHI3%a...
November 2016: Sleep Medicine
https://www.readbyqxmd.com/read/27895576/sleep-disturbances-among-older-adults-in-the-united-states-2002-2012-nationwide-inpatient-rates-predictors-and-outcomes
#7
Alyssa A Gamaldo, May A Beydoun, Hind A Beydoun, Hailun Liang, Rachel E Salas, Alan B Zonderman, Charlene E Gamaldo, Shaker M Eid
Objective/Background: We examined the rates, predictors, and outcomes [mortality risk (MR), length of stay (LOS), and total charges (TC)] of sleep disturbances in older hospitalized patients. Patients/Methods: Using the U.S. Nationwide Inpatient Sample database (2002-2012), older patients (≥60 years) were selected and rates of insomnia, obstructive sleep apnea (OSA) and other sleep disturbances (OSD) were estimated using ICD-9CM. TC, adjusted for inflation, was of primary interest, while MR and LOS were secondary outcomes...
2016: Frontiers in Aging Neuroscience
https://www.readbyqxmd.com/read/27795883/a-comparison-of-outcomes-of-bariatric-surgery-in-patient-greater-than-70-with-18-month-of-follow-up
#8
Hinali Zaveri, Amit Surve, Daniel Cottam, Christina Summerhays, Austin Cottam, Christina Richards, LeGrand Belnap, Walter Medlin
BACKGROUND: There is a scarcity of data available to determine the safety and effectiveness of bariatric surgery in the elderly population. Additionally, there are no studies showing the effect of the single anastomosis duodenal switch (SADS) has on the elderly obese, in comparison with other more popular procedures. Here we compare laparoscopic gastric band surgery (LAGB), Laparoscopic Roux-en-Y gastric bypass surgery (LRYGB), and the SADS to analyze the weight loss, perioperative and postoperative morbidity in the patients >70 years of age at a single US center...
2016: SpringerPlus
https://www.readbyqxmd.com/read/27677047/sleep-breathing-disorders-and-cognitive-decline-in-healthy-elderly-followed-for-eight-years-the-proof-cohort
#9
Magali Saint Martin, Emilia Sforza, Emilie Crawford-Achour, Lefèvre Pascal, Georges Lienard, Roche Frédéric
OBJECTIVE: Sleep breathing disorders (SBD) are the most common sleep disorders frequently under-diagnosed in elderly populations. However, it is it well known that this disorder may contribute to the age-related cognitive decline. In a cohort of healthy elderly subjects, we performed an 8-year longitudinal study to assess whether changes in cognitive function occur in untreated SBD elderly and the nocturnal factors implicated in these changes. MATERIAL/PATIENTS AND METHODS: A total of 559 participants of the community-based PROOF study aged 67years at the study entry and free from neurological disorders were examined...
September 2016: Annals of Physical and Rehabilitation Medicine
https://www.readbyqxmd.com/read/27670855/frailty-and-sarcopenia-in-elderly
#10
John E Morley
Frailty is a pre-disability syndrome where an older person can be identified as being at risk when exposed to stressors associated with high risk for disability or needing to be hospitalized. Two major frailty definitions exist. The physical phenotype of frailty and the multiple deficit model. A simple frailty screening tool-FRAIL-has been validated. Treatment of frailty involves resistance exercise, optimization of nutrition, and treatment of fatigue (sleep apnea, depression), treatable causes of weight loss and adjustment of polypharmacy...
December 2016: Wiener Klinische Wochenschrift
https://www.readbyqxmd.com/read/27666578/risk-of-tinnitus-in-patients-with-sleep-apnea-a-nationwide-population-based-case-control-study
#11
Malcolm Koo, Juen-Haur Hwang
OBJECTIVE: To investigate the risk of tinnitus in patients with sleep disturbance or sleep apnea. STUDY DESIGN: Case control study. METHODS: We identified 21,798 middle-aged and elderly patients with otolaryngologist-diagnosed tinnitus between January 1, 2000, and December 31, 2012, from the Longitudinal Health Insurance Database 2000 of the Taiwan National Health Insurance Research Database. A total of 108,990 controls were also identified from the same database based on frequency-matching on 10-year age interval, sex, and year of index date of the cases...
September 26, 2016: Laryngoscope
https://www.readbyqxmd.com/read/27579333/the-association-between-obstructive-sleep-apnea-and-depression-in-older-adults
#12
Mohammad Farajzadeh, Meimanat Hosseini, Jamileh Mohtashami, Samira Chaibakhsh, Mansoureh Zagheri Tafreshi, Reza Ghanei Gheshlagh
BACKGROUND: Depression is the most frequent psychiatric disorder among the elderly. Obstructive sleep apnea (OSA) is a chronic and prevalent disease that has an ambiguous role in triggering depression. Several researches with contradictory findings have been performed about the association between OSA and depression. OBJECTIVES: This study aimed to investigate the association between OSA and depression among elderly. PATIENTS AND METHODS: A total of 350 home residing elderly took part in this case-control study...
June 2016: Nursing and Midwifery Studies
https://www.readbyqxmd.com/read/27568340/prevalence-of-obstructive-sleep-apnea-in-the-general-population-a-systematic-review
#13
REVIEW
Chamara V Senaratna, Jennifer L Perret, Caroline J Lodge, Adrian J Lowe, Brittany E Campbell, Melanie C Matheson, Garun S Hamilton, Shyamali C Dharmage
With this systematic review we aimed to determine the prevalence of obstructive sleep apnea (OSA) in adults in the general population and how it varied between population sub-groups. Twenty-four studies out of 3807 found by systematically searching PubMed and Embase databases were included in this review. Substantial methodological heterogeneity in population prevalence studies has caused a wide variation in the reported prevalence, which, in general, is high. At ≥5 events/h apnea-hypopnea index (AHI), the overall population prevalence ranged from 9% to 38% and was higher in men...
July 18, 2016: Sleep Medicine Reviews
https://www.readbyqxmd.com/read/27544832/risk-factors-of-osteoporosis-in-healthy-elderly-with-unrecognized-obstructive-sleep-apnea-role-of-physical-activity
#14
Emilia Sforza, Magali Saint Martin, Thierry Thomas, Philippe Collet, Martin Garet, Jean Claude Barthélémy, Frédéric Roche
OBJECTIVE: Several studies suggest a relationship between bone mineral density (BMD) anthropometric and metabolic variables, and obstructive sleep apnea (OSA); all of these factors have an effect on osteoporosis (OS) risk. This cross-sectional study explores these associations in a large sample of older subjects with and without OSA. METHODS: Volunteers were recruited from the PROgnostic indicator OF cardiovascular and cerebrovascular events survey. A total of 461 subjects, aged 68...
June 2016: Sleep Medicine
https://www.readbyqxmd.com/read/27509339/-sleep-disturbances-in-the-elderly
#15
Richard Mahlberg
Sleep disturbances are common in the elderly. Endogen regulation mechanisms are often unstable. Light treatment and melatonin are proved chronobiological interventions. Cataract surgery is effective to enhance the sleep-wake-rhythm.Mandibular advancement devices are a reliable alternative to continuous positive air pressure (CPAP) in obstructive sleep apnea syndrome (OSAS).
August 2016: Deutsche Medizinische Wochenschrift
https://www.readbyqxmd.com/read/27373038/-prevalence-of-obstructive-sleep-apnea-hypopnea-syndrome-in-adults-aged-over-60-yeaes-in-dongying-city
#16
Yi Su, Weiwei Xu, Xiangyun Wang, Zhili Zhang, Yingchun Cao, Qiuhong Yu, Jiandong Li
OBJECTIVE: To survey the prevalence of obstructive sleep apnea-hypopnea syndrome(OSAHS) in adults aged over 60 years in Dongying city,and analyze the risk factors and the extent of damage to the quality of life for the elderly to provide the basis for prevention and treatment of OSAHS people. METHOD: One thousand subjects were derived from a random cluster sampling in seven districts of Dongying city:they were asked to answer the questions from questionnaires. According to the questionnaire scoring, 100 subjects in high-risk group were selected randomly to make polysomnography monitoring for a whole night,so that the prevalence of the disease was calculated and the related risk factors were analyzed; elderly patients diagnosed with OSAHS were asked to assess the quality of life assessment questionnaire by face to face to understand the quality of life dimensions injury...
February 2016: Journal of Clinical Otorhinolaryngology, Head, and Neck Surgery
https://www.readbyqxmd.com/read/27350397/cerebral-hypoperfusion-and-glucose-hypometabolism-key-pathophysiological-modulators-promote-neurodegeneration-cognitive-impairment-and-alzheimer-s-disease
#17
Mak Adam Daulatzai
Aging, hypertension, diabetes, hypoxia/obstructive sleep apnea (OSA), obesity, vitamin B12/folate deficiency, depression, and traumatic brain injury synergistically promote diverse pathological mechanisms including cerebral hypoperfusion and glucose hypometabolism. These risk factors trigger neuroinflammation and oxidative-nitrosative stress that in turn decrease nitric oxide and enhance endothelin, Amyloid-β deposition, cerebral amyloid angiopathy, and blood-brain barrier disruption. Proinflammatory cytokines, endothelin-1, and oxidative-nitrosative stress trigger several pathological feedforward and feedback loops...
June 27, 2016: Journal of Neuroscience Research
https://www.readbyqxmd.com/read/27349525/nocturia-other-lower-urinary-tract-symptoms-and-sleep-dysfunction-in-a-community-dwelling-cohort-of-men
#18
Sean A Martin, Sarah L Appleton, Robert J Adams, Anne W Taylor, Peter G Catcheside, Andrew Vakulin, R Douglas McEvoy, Nick A Antic, Gary A Wittert
OBJECTIVES: To examine the influence of obstructive sleep apnea (OSA) on nocturia, controlling for their shared co-morbidities, in a population of community-based middle aged to elderly men. METHODS: Participants were drawn from a randomly selected, community-dwelling cohort of men in Adelaide, Australia. Seven hundred and eight men (mean: 60.7 [41.6-88.2] years) who had polysomnography recordings, complete lower urinary tract symptoms (LUTS) measures (International Prostate Symptom Score), without prostate or bladder cancer and/or surgery, and no prior OSA diagnosis were selected...
November 2016: Urology
https://www.readbyqxmd.com/read/27339162/dysfunctional-sensory-modalities-locus-coeruleus-and-basal-forebrain-early-determinants-that-promote-neuropathogenesis-of-cognitive-and-memory-decline-and-alzheimer-s-disease
#19
REVIEW
Mak Adam Daulatzai
Sporadic Alzheimer's disease (AD) is a devastating neurodegenerative disorder. It is essential to unravel its etiology and pathogenesis. This should enable us to study the presymptomatic stages of the disease and to analyze and reverse the antemortem behavioral, memory, and cognitive dysfunction. Prima facie, an ongoing chronic vulnerability involving neural insult may lead normal elderly to mild cognitive impairment (MCI) and then to AD. Development of effective preventive and therapeutic strategies to thwart the disease pathology obviously requires a thorough delineation of underlying disruptive neuropathological processes...
October 2016: Neurotoxicity Research
https://www.readbyqxmd.com/read/27336305/supra-epiglottic-upper-airway-volume-in-elderly-patients-with-obstructive-sleep-apnea-hypopnea-syndrome
#20
Claire Boutet, Syad Abdirahman Mohamed Moussa, Sébastien Celle, Bernard Laurent, Jean-Claude Barthélémy, Fabrice-Guy Barral, Frédéric Roche
OBJECTIVE: Small upper airway measurements areas and high body mass index are recognized risk factors for obstructive sleep apnea syndrome (OSAS) in non-elderly populations; however, there is limited information regarding elderly patients. We evaluated whether upper airway volume is associated with OSAS and OSAS treated with continuous positive airway pressure (CPAP) treatment and whether BMI is correlated with upper airway volume and measurements in elderly subjects. METHODS: In 60 volunteers aged 75...
2016: PloS One
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