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https://www.readbyqxmd.com/read/27893604/implementation-of-preexposure-prophylaxis-for-human-immunodeficiency-virus-prevention-among-men-who-have-sex-with-men-at-a-new-england-sexually-transmitted-diseases-clinic
#1
Philip A Chan, Tiffany R Glynn, Catherine E Oldenburg, Madeline C Montgomery, Ashley E Robinette, Alexi Almonte, Julia Raifman, Leandro Mena, Rupa Patel, Kenneth H Mayer, Laura S Beauchamps, Amy S Nunn
BACKGROUND: Preexposure prophylaxis (PrEP) is efficacious in preventing human immunodeficiency virus (HIV) among men who have sex with men (MSM). We assessed PrEP uptake among MSM presenting for services at a sexually transmitted diseases (STD) clinic. METHODS: Men who have sex with men presenting to the Rhode Island STD Clinic between October 2013 and November 2014 were educated about, and offered, PrEP. We categorized PrEP engagement using an implementation cascade to describe gaps in uptake which described MSM who: (1) were educated about PrEP, (2) indicated interest, (3) successfully received follow-up contact, (4) scheduled an appointment, (5) attended an appointment, and (6) initiated PrEP (ie, received a prescription)...
November 2016: Sexually Transmitted Diseases
https://www.readbyqxmd.com/read/27893594/sexually-transmitted-disease-program-evolution-in-response-to-changes-in-the-public-health-environment-a-massachusetts-example
#2
Marion W Carter, Katherine K Hsu, Penny S Loosier, Brandy L Peterson Maddox, Sonal R Doshi, Karen Kroeger, Kevin Cranston
BACKGROUND: In 2008, the line item supporting sexually transmitted disease (STD) services in the Massachusetts state budget was cut as a result of budget shortfalls. Shortly thereafter, direct provision of STD clinical services supported by the Massachusetts Department of Public Health (MDPH) was suspended. Massachusetts Department of Public Health requested an initial assessment of its internal response and impact in 2010. A follow-up assessment occurred in September 2013. METHODS: In 2010 and 2013, 39 and 46 staff, respectively, from MDPH and from clinical partner agencies, were interviewed about changes in the role of the MDPH, partnerships, STD services, challenges, and recommendations...
November 2016: Sexually Transmitted Diseases
https://www.readbyqxmd.com/read/27890946/prevalence-of-asymptomatic-infections-in-sexually-transmitted-diseases-attendees-diagnosed-with-bacterial-vaginosis-vaginal-candidiasis-and-trichomoniasis
#3
R Rajalakshmi, S Kalaivani
BACKGROUND: Sexually transmitted diseases (STD) are a major health problem affecting mostly young people in both developing and developed countries. STD in women causes both acute morbidity and complications such as infertility, ectopic pregnancy, low-birth weight, and prematurity. AIMS: The aim of the study is to assess the prevalence of bacterial vaginosis, vaginal candidiasis, and trichomoniasis among asymptomatic females attending STD outpatient department in a tertiary care hospital in South India...
July 2016: Indian Journal of Sexually Transmitted Diseases
https://www.readbyqxmd.com/read/27866390/school-based-hiv-std-testing-behaviors-and-motivations-among-black-and-hispanic-teen-msm-results-from-a-formative-evaluation
#4
Elana Morris, Pablo Topete, Catherine N Rasberry, Catherine A Lesesne, Elizabeth Kroupa, Lisa Carver
BACKGROUND: This evaluation explores experiences with, and motivations for, human immunodeficiency virus (HIV) and sexually transmitted disease (STD) testing among black and Hispanic school-aged young men who have sex with men (YMSM). METHODS: Participants were recruited at community-based organizations that serve YMSM in New York City, Philadelphia, and San Francisco. Eligible participants were 13- to 19-year-old black or Hispanic males who reported attraction to or sexual behavior with other males and/or identified as gay or bisexual, and attended at least 90 days of school in the previous 18 months...
December 2016: Journal of School Health
https://www.readbyqxmd.com/read/27832703/hiv-and-sti-knowledge-testing-and-risk-among-adult-crack-users-in-mexico-city-baseline-findings-from-a-feasibility-study
#5
Alice Cepeda, Jessica Frankeberger, Jennifer L Bailey, Kathryn M Nowotny, Guillermina Natera-Rey, Avelardo Valdez
Recent research has documented crack cocaine's increasing spread in Mexico, which is likely to contribute to the rapid transmission of HIV and other sexually transmitted infections (STIs). In Mexico, crack use is increasing most rapidly in vulnerable, hard-to-reach populations, where little is known about risk behaviors. This report aims to present baseline data regarding HIV and STI knowledge and testing prevalence from an innovative projection mapping HIV intervention, in which 3-D illusions, animation, and visual text graphics and sound are projected onto buildings with health messages that were designed to disrupt everyday life and connect with the target population...
November 10, 2016: AIDS Care
https://www.readbyqxmd.com/read/27827386/examining-the-themes-of-std-related-internet-searches-to-increase-specificity-of-disease-forecasting-using-internet-search-terms
#6
Amy K Johnson, Tarek Mikati, Supriya D Mehta
US surveillance of sexually transmitted diseases (STDs) is often delayed and incomplete which creates missed opportunities to identify and respond to trends in disease. Internet search engine data has the potential to be an efficient, economical and representative enhancement to the established surveillance system. Google Trends allows the download of de-identified search engine data, which has been used to demonstrate the positive and statistically significant association between STD-related search terms and STD rates...
November 9, 2016: Scientific Reports
https://www.readbyqxmd.com/read/27812208/viability-pcr-shows-that-naat-detects-a-high-proportion-of-dna-from-non-viable-chlamydia-trachomatis
#7
Kevin J H Janssen, Christian J P A Hoebe, Nicole H T M Dukers-Muijrers, Lisanne Eppings, Mayk Lucchesi, Petra F G Wolffs
OBJECTIVES: According to the current guidelines for laboratory diagnosis of sexually transmitted infections (STIs), nucleic acid amplification tests (NAATs) are the preferred diagnostic method for Chlamydia trachomatis (CT) infections. However, NAATs amplify the available target DNA without discriminating between DNA originating from viable or non-viable CT. Assessing CT viability will provide more insights in the clinical and public health relevance of a CT positive test result. The aim of this study was to technically validate and implement viability-PCR (V-PCR) to asses CT viability...
2016: PloS One
https://www.readbyqxmd.com/read/27797219/clinical-factors-associated-with-specimen-adequacy-for-conventional-cervical-cytology-in-thammasat-university-hospital-thailand
#8
Akegapot Anantaworapot, Sakol Manusook, Chamnan Tanprasertkul, Supapen Lertvutivivat, Athita Chanthasenanont, Kornkarn Bhamarapravatana, Komsun Suwannarurk
PURPOSE: To study clinical factors related to adequacy of transformation zone (TZ) components in cervical smears. MATERIALS AND METHODS: Medical and Papanicolaou (Pap) smear reports from Thammasat University Hospital, Thailand during January to December 2015 were collected. Demographic data was reviewed by attending physicians and impact of clinical factors onTZ adequacy was primary outcome. A total of 3,251 smears were reviewed. Finally, 2,098 smears met The inclusion criteria and enrolled into this study...
2016: Asian Pacific Journal of Cancer Prevention: APJCP
https://www.readbyqxmd.com/read/27792685/changes-in-condomless-sex-and-serosorting-among-men-who-have-sex-with-men-after-hiv-diagnosis
#9
Christine M Khosropour, Julia C Dombrowski, Roxanne P Kerani, David A Katz, Lindley A Barbee, Matthew R Golden
BACKGROUND: Among men who have sex with men (MSM) diagnosed with HIV, high-risk sexual behaviors may decline in the year after diagnosis. The sustainability of these changes is unknown. METHODS: We created a retrospective cohort (Seroconversion Cohort) of MSM attending an STD clinic in Seattle, Washington who tested HIV positive between 2001 and 2013 and had a negative HIV test <2 years before diagnosis. We randomly selected 1000 HIV-negative controls (men who always tested HIV negative) who were frequency-matched to the Seroconversion Cohort based on HIV diagnosis year...
December 1, 2016: Journal of Acquired Immune Deficiency Syndromes: JAIDS
https://www.readbyqxmd.com/read/27787348/budgetary-impact-of-compliance-with-sti-screening-guidelines-in-persons-living-with-hiv
#10
Ellen F Eaton, Kathryn Hudak, Christina A Muzny
INTRODUCTION: The 2015 Centers for Disease Control (CDC) Sexually Transmitted Diseases (STD) Treatment Guidelines recommend annual screening of all persons living with HIV (PLWH) for N. gonorrhoeae, C. trachomatis, and syphilis; annual T. vaginalis screening is recommended for HIV-infected women. The study objective is to evaluate the budgetary impact of sexually transmitted infection (STI) screening. We hypothesized that recommended STI screening is costly and would not be covered in full by insurers...
October 19, 2016: Journal of Acquired Immune Deficiency Syndromes: JAIDS
https://www.readbyqxmd.com/read/27784254/challenges-and-persistent-questions-in-treatment-of-trichomoniasis
#11
Patrícia de Brum Vieira, Tiana Tasca, W Evan Secor
Trichomoniasis is a sexually transmitted disease (STD) caused by infection with the protozoan parasite Trichomonas vaginalis. It is considered the most prevalent non-viral sexually transmitted disease worldwide. Recently, the infection has been associated with adverse outcomes of pregnancy and increased risks of HIV acquisition and transmission, besides the association with cervical and prostate cancers. The consequences of trichomoniasis are likely much greater than previously recognized, both at the individual and the community level...
October 25, 2016: Current Topics in Medicinal Chemistry
https://www.readbyqxmd.com/read/27775395/modeling-the-role-of-healthcare-access-inequalities-in-epidemic-outcomes
#12
Oscar Patterson-Lomba, Muntaser Safan, Sherry Towers, Jay Taylor
Urban areas, with large and dense populations, offer conditions that favor the emergence and spread of certain infectious diseases. One common feature of urban populations is the existence of large socioeconomic inequalities which are often mirrored by disparities in access to healthcare. Recent empirical evidence suggests that higher levels of socioeconomic inequalities are associated with worsened public health outcomes, including higher rates of sexually transmitted diseases (STD's) and lower life expectancy...
October 1, 2016: Mathematical Biosciences and Engineering: MBE
https://www.readbyqxmd.com/read/27765021/hiv-epidemiology-and-responses-among-men-who-have-sex-with-men-and-transgender-individuals-in-china-a-scoping-review
#13
Songyuan Tang, Weiming Tang, Kathrine Meyers, Polin Chan, Zhongdan Chen, Joseph D Tucker
BACKGROUND: Despite global efforts to control HIV among key populations, new infections among men who have sex with men (MSM) and transgender (TG) individuals are still increasing. The increasing HIV epidemic among MSM/TG in China indicates that more effective services are urgently needed. However, policymakers and program managers must have a clear understanding of MSM/TG sexual health in China to improve service delivery. To meet this need, we undertook a scoping review to summarize HIV epidemiology and responses among MSM and TG individuals in China...
October 20, 2016: BMC Infectious Diseases
https://www.readbyqxmd.com/read/27738123/the-effect-of-four-different-feeding-regimens-from-rearing-period-to-sexual-maturity-on-breast-muscle-protein-turnover-in-broiler-breeder-parent-stock
#14
Karen Vignale, Justina V Caldas, Judy A England, Nirun Boonsinchai, Phiphob Sodsee, Monticha Putsakum, Erik D Pollock, Sami Dridi, Craig N Coon
A study was conducted to evaluate the effect of four different feeding regimens on breast muscle protein turnover in broiler breeder Cobb-500 parent stock (PS) pullets and breeder hens. The four feeding regimens based on BW curves utilized for the study were as follows: Everyday feeding (STD-ED) (Cobb Standard BW curve), skip-a-day feeding (STD-SKIP) (Cobb Standard BW curve), lighter BW (LBW-SKIP) (BW curve 20% under), and heavier BW (HBW-SKIP) (BW curve 20% over). Each feeding regimen was provided to pullets from 4 wk to 21 wk of age...
October 12, 2016: Poultry Science
https://www.readbyqxmd.com/read/27719662/the-importance-of-military-conscripts-for-surveillance-of-human-immunodeficiency-virus-infection-and-risk-behavior-in-thailand
#15
Aladdin Shadyab, Kenrad E Nelson, Ram Rangsin
The human immunodeficiency virus (HIV) epidemic in Thailand was first recognized in 1988 among injection drug users (IDUs) in Bangkok. Soon thereafter, HIV infections were reported among female sex workers (FSWs) and men attending sexually transmitted disease (STD) clinics. Routine serological surveillance for HIV began in 1991 among young men who were conscripted annually into the Royal Thai Army (RTA). The data from these populations provided a national population-based sample to determine sexual behaviors and HIV prevalence among sexually active young men...
October 6, 2016: Current HIV Research
https://www.readbyqxmd.com/read/27710087/projectheartforgirls-com-development-of-a-web-based-hiv-std-prevention-program-for-adolescent-girls-emphasizing-sexual-communication-skills
#16
Laura Widman, Carol E Golin, Seth M Noar, Joy Massey, Mitchell J Prinstein
This article describes the development of ProjectHeartforGirls.com , an interactive web-based program designed to improve sexual communication skills and reduce the risk of HIV/STDs among adolescent girls, a population at heightened risk for negative sexual health outcomes (Centers for Disease Control and Prevention, 2013). Although sexual communication is a critical predictor of safer sex among teens, there are few online interventions that target these skills as a central program component. We developed ProjectHeartforGirls...
October 2016: AIDS Education and Prevention: Official Publication of the International Society for AIDS Education
https://www.readbyqxmd.com/read/27697044/challenges-and-persistent-questions-in-treatment-of-trichomoniasis
#17
Patrícia de Brum Vieira, Tiana Tasca, W Evan Secor
Trichomoniasis is a sexually transmitted disease (STD) caused by infection with the protozoan parasite Trichomonas vaginalis. It is considered the most prevalent non-viral sexually transmitted disease worldwide. Recently, the infection has been associated with adverse outcomes of pregnancy and increased risks of HIV acquisition and transmission, besides the association with cervical and prostate cancers. The consequences of trichomoniasis are likely much greater than previously recognized, both at the individual and the community level...
September 30, 2016: Current Topics in Medicinal Chemistry
https://www.readbyqxmd.com/read/27685158/anticipated-notification-of-sexual-partners-following-std-diagnosis-among-men-who-have-sex-with-men-and-transgender-women-in-lima-peru-a-mixed-methods-analysis
#18
Jesse L Clark, Amaya G Perez-Brumer, Eddy R Segura, Hector J Salvatierra, Jorge Sanchez, Javier R Lama
BACKGROUND: New strategies to support partner notification (PN) are critical for STD control and require detailed understanding of how specific individual and partnership characteristics guide notification decisions. METHODS: From 2011 to 2012, 397 MSM and TW recently diagnosed with HIV, syphilis, or another STD completed a survey on anticipated notification of recent sexual partners and associated factors. Qualitative interviews were conducted with a subset of participants to provide further depth to quantitative findings...
2016: PloS One
https://www.readbyqxmd.com/read/27671357/measuring-adolescent-human-papillomavirus-vaccine-coverage-a-match-of-sexually-transmitted-disease-clinic-and-immunization-registry-data
#19
Preeti Pathela, Kelly Jamison, Vikki Papadouka, Rezaul Kabir, Lauri E Markowitz, Eileen F Dunne, Julia A Schillinger
PURPOSE: Human papillomavirus (HPV) vaccine is recommended for adolescents. By the end of 2013, 64% of female and 40% of male New York City residents aged 13-18 years had received ≥1 HPV vaccine dose. Adolescents attending sexually transmitted disease (STD) clinics are at high risk for HPV exposure and could benefit from vaccination. Our objective was to estimate HPV vaccination coverage for this population. METHODS: We matched records of New York City's STD clinic patients aged 13-18 years during 2010-2013 with the Citywide Immunization Registry...
September 23, 2016: Journal of Adolescent Health: Official Publication of the Society for Adolescent Medicine
https://www.readbyqxmd.com/read/27643640/2-methyl-4-5-nitroimidazole-derivatives-potentiated-against-sexually-transmitted-trichomonas-design-synthesis-biology-and-3d-qsar-study
#20
Dhanaraju Mandalapu, Bhavana Kushwaha, Sonal Gupta, Nidhi Singh, Mahendra Shukla, Jitendra Kumar, Dilip K Tanpula, Satya N Sankhwar, Jagdamba P Maikhuri, Mohammad I Siddiqi, Jawahar Lal, Gopal Gupta, Vishnu L Sharma
Trichomoniasis is the most prevalent, non-viral sexually transmitted diseases (STD) caused by amitochondriate protozoan Trichomonas vaginalis. Increased resistance of T. vaginalis to the marketed drug Metronidazole necessitates the development of newer chemical entities. A library of sixty 2-methyl-4/5-nitroimidazole derivatives was synthesized via nucleophilic ring opening reaction of epoxide and the efficacies against drug-susceptible and -resistant Trichomonas vaginalis were evaluated. All the molecules except two were found to be active against both susceptible and resistant strains with MICs ranging 8...
September 4, 2016: European Journal of Medicinal Chemistry
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