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Chronic kidney fatigue

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https://www.readbyqxmd.com/read/28621633/fatigue-after-liver-transplant-and-combined-liver-and-kidney-transplant
#1
Christian Benzing, Felix Krenzien, Nicco Krezdorn, Georg Wiltberger, Andreas Hinz, Julia Förster, Georgi Atanasov, Moritz Schmelzle, Heide Glaesmer, Hans Michael Hau, Michael Bartels
OBJECTIVES: To date, fatigue is still poorly understood in recipients of orthotopic liver transplant and simultaneous/sequential liver and kidney transplant procedures. The present study examined the appearance of fatigue in patients who received orthotopic liver and sequential liver and kidney transplant procedures compared with the general population and the influence of various clinical and socioeconomic factors on fatigue levels. MATERIALS AND METHODS: The Multidimensional Fatigue Inventory survey was sent to all patients with a history of orthotopic liver and simultaneous/sequential liver and kidney transplant...
June 16, 2017: Experimental and Clinical Transplantation
https://www.readbyqxmd.com/read/28612998/symptom-experience-in-non-dialysis-dependent-chronic-kidney-disease-a-qualitative-descriptive-study
#2
Karen Pugh-Clarke, Sue Cheryl Read, Julius Sim
BACKGROUND: Studies indicate that symptoms attributable to impaired kidney function are important determinants of quality of life and functional status in patients with chronic kidney disease (CKD). Accordingly, symptom assessment and subsequent control are prerequisites of high-quality care in this patient population. Whilst symptom burden in patients with advanced CKD managed without dialysis has been likened to that of palliative care cancer populations, there is little information about the nature and range of symptoms in earlier stages of the CKD trajectory...
June 14, 2017: Journal of Renal Care
https://www.readbyqxmd.com/read/28573387/the-impact-of-change-of-renal-replacement-therapy-modality-on-sleep-quality-in-patients-with-end-stage-renal-disease-a-systematic-review-and-meta-analysis
#3
REVIEW
C Kennedy, S A Ryan, T Kane, R W Costello, P J Conlon
BACKGROUND: Sleep disorders are common and multi-factorial in patients with advanced chronic kidney disease and end-stage renal disease (ESRD). Sleep disorders and disturbance have a negative impact on wellbeing and quality of life. OBJECTIVE: To assess the impact of a change in renal replacement therapy (RRT) modality on sleep quality and sleep disturbance in patients with ESRD. DATA SOURCES: Multiple electronic databases were searched without publication type/period restrictions...
June 1, 2017: Journal of Nephrology
https://www.readbyqxmd.com/read/28554920/physical-activity-immune-function-and-inflammation-in-kidney-patients-the-pink-study-a-feasibility-trial-protocol
#4
Patrick James Highton, Jill Neale, Thomas J Wilkinson, Nicolette C Bishop, Alice C Smith
INTRODUCTION: Patients with chronic kidney disease (CKD) display increased infection-related mortality and elevated cardiovascular risk only partly attributed to traditional risk factors. Patients with CKD also exhibit a pro-inflammatory environment and impaired immune function. Aerobic exercise has the potential to positively impact these detriments, but is under-researched in this patient population. This feasibility study will investigate the effects of acute aerobic exercise on inflammation and immune function in patients with CKD to inform the design of larger studies intended to ultimately influence current exercise recommendations...
May 29, 2017: BMJ Open
https://www.readbyqxmd.com/read/28412933/beyond-quality-of-life-a-cross-sectional-study-on-the-mental-health-of-patients-with-chronic-kidney-disease-undergoing-dialysis-and-their-caregivers
#5
Beatriz Dos Santos Pereira, Neimar da Silva Fernandes, Nayara Pires de Melo, Renata Abrita, Fabiane Rossi Dos Santos Grincenkov, Natália Maria da Silva Fernandes
BACKGROUND: Patients with terminal chronic kidney disease (CKDT) requiring renal replacement therapies (RRT) undergo important changes in living habits and frequently need caregiving. These patients and their caregivers are risk groups for the development of physical and psychological symptoms. This study aimed to evaluate the prevalence of anxiety, depression, stress, fatigue, social support, and quality of life in patients with CKD and their caregivers. METHOD: This cross sectional study was conducted with 21 patients and their caregivers, from January to September 2015...
April 17, 2017: Health and Quality of Life Outcomes
https://www.readbyqxmd.com/read/28329420/towards-a-symptom-cluster-model-in-chronic-kidney-disease-a-structural-equation-approach
#6
Hayfa Almutary, Clint Douglas, Ann Bonner
AIMS: To test a symptom cluster model in chronic kidney disease patients based on the Theory of Unpleasant Symptoms, accounting for the relationships between influencing factors, symptom experience and consequences for quality of life. BACKGROUND: The evaluation of symptom clusters is a new field of scientific inquiry directed toward more focused symptom management. Yet, little is known about relationships between symptom clusters, predictors and the synergistic effect of multiple symptoms on outcomes...
March 22, 2017: Journal of Advanced Nursing
https://www.readbyqxmd.com/read/28321327/physical-activity-in-patients-treated-with-peritoneal-dialysis-a-protocol-for-a-systematic-review
#7
Tharshika Thangarasa, Rameez Imtiaz, Swapnil Hiremath, Deborah Zimmerman
BACKGROUND: Patients with chronic diseases are known to benefit from exercise. Despite a lack of compelling evidence, patients with end-stage kidney disease treated with peritoneal dialysis are often discouraged from participating in exercise programs that include resistance training due to concerns about the development of hernias and leaks. The actual effects of physical activity with or without structured exercise programs for these patients remain unclear. The purpose of this study is to more completely define the risks and benefits of physical activity in the end-stage kidney disease population treated with peritoneal dialysis...
2017: Canadian Journal of Kidney Health and Disease
https://www.readbyqxmd.com/read/28281085/efficacy-and-safety-of-sofosbuvir-based-regimens-in-chronic-hepatitis-c-patients-on-dialysis
#8
Narendra S Choudhary, Amit Kumar, Vijay Bodh, Shyam Bihari Bansal, Reetesh Sharma, Manish Jain, Sanjiv Saigal, Neeraj Saraf
INTRODUCTION: Patients with end-stage renal disease (ESRD) have poor treatment tolerance and outcome to interferon-based regimens. Sofosbuvir-based regimens have improved treatment success in chronic hepatitis C. There is limited data in ESRD patients as sofosbuvir is excreted by the kidney. Several small studies have shown good results. METHODS: Sixteen consecutive patients of ESRD (on dialysis) and chronic hepatitis C were treated with sofosbuvir-based regimens as they were prospective kidney transplantation recipients, at a tertiary care center in north India...
March 2017: Indian Journal of Gastroenterology: Official Journal of the Indian Society of Gastroenterology
https://www.readbyqxmd.com/read/28144977/changing-landscape-for-peritoneal-dialysis-optimizing-utilization
#9
Martin J Schreiber
The future growth of peritoneal dialysis (PD) will be directly linked to the shift in US healthcare to a value-based payment model due to PD's lower yearly cost, early survival advantage over in-center hemodialysis, and improved quality of life for patients treating their kidney disease in the home. Under this model, nephrology practices will need an increased focus on managing the transition from chronic kidney disease to end-stage renal disease (ESRD), providing patient education with the aim of accomplishing modality selection and access placement ahead of dialysis initiation...
March 2017: Seminars in Dialysis
https://www.readbyqxmd.com/read/28123560/adefovir-dipivoxil-induced-fanconi-syndrome-and-its-predictive-factors-a-study-of-28-cases
#10
Yong Lin, Fan Pan, Yingchao Wang, Ziqian Chen, Chun Lin, Lvfeng Yao, Xin Zhang, Rui Zhou, Chen Pan
The aim of the present study was to identify monitoring and prevention measures as well as predictive factors for early detection of renal toxicity associated with long-term administration of adefovir dipivoxil in order to avoid progression to Fanconi syndrome. Clinical data of 28 patients with Fanconi syndrome caused by long-term administration of adefovir dipivoxil for the treatment of chronic hepatitis B virus (HBV) infection were collected pre-and post-administration for analysis. Patients presented with fatigue, progressive systemic pain in multiple bones and joints, as well as difficulty in walking and pathological fractures in a number of severe cases...
January 2017: Oncology Letters
https://www.readbyqxmd.com/read/28111055/oral-anticoagulant-use-in-octogenarian-european-patients-with-atrial-fibrillation-a-subanalysis-of-prefer-in-af
#11
Olivier Hanon, Jean-Sébastien Vidal, Jean-Yves Le Heuzey, Paulus Kirchhof, Raffaele De Caterina, Josef Schmitt, Petra Laeis, Pier Mannuccio Mannucci, Maura Marcucci
BACKGROUND: Few studies describe oral anticoagulant (OAC) prescription practices in very elderly patients with atrial fibrillation (AF). METHODS: In this sub-analysis of the PREFER in AF study, performed in 2012, patients were stratified according to age (<80 [n=5565] and ≥80years [n=1660]) and OAC treatment. Factors associated with OAC prescription were analyzed in a multivariate logistic regression model with backward elimination of variables least associated with OAC use...
April 1, 2017: International Journal of Cardiology
https://www.readbyqxmd.com/read/28024112/left-sided-living-kidney-donation-leads-to-transiently-reduced-adrenocortical-responsiveness
#12
F Burn, C Schirpenbach, M Bidlingmaier, M Reincke, D Vetter, D Weishaupt, J G Brockmann, M K Müller, M Weber, F Dahm, A Nocito
Living kidney donation is safe and established, but can lead to long-term complications such as chronic fatigue. Since the adrenal vein is usually transected during left-sided donor nephrectomy-which is not necessary on the right-we hypothesized that venous congestion might lead to an impairment of adrenal function, offering a possible explanation. In this prospective open label, monocentric cohort study, adrenal function was compared in left- and right-sided living kidney donors. The primary endpoint was plasma cortisol response to low-dose adrenocorticotropic hormone (ACTH) stimulation...
December 26, 2016: American Journal of Transplantation
https://www.readbyqxmd.com/read/28006774/the-prevalence-of-fabry-disease-in-patients-with-chronic-kidney-disease-in-turkey-the-turkfab-study
#13
Kultigin Turkmen, Aydın Guclu, Garip Sahin, Ismail Kocyigit, Levent Demirtas, Fatih Mehmet Erdur, Erkan Sengül, Oktay Ozkan, Habib Emre, Faruk Turgut, Hilmi Unal, Murat Karaman, Cengiz Acıkel, Hasan Esen, Ebru Balli, Gulfidan Bıtırgen, Halil Zeki Tonbul, Mahmut Ilker Yılmaz, Alberto Ortiz
BACKGROUND/AIMS: Fabry disease is a treatable cause of chronic kidney disease (CKD) characterized by a genetic deficiency of α-galactosidase A. European Renal Best Practice (ERBP) recommends screening for Fabry disease in CKD patients. However, this is based on expert opinion and there are no reports of the prevalence of Fabry disease in stage 1-5 CKD. Hence, we investigated the prevalence of Fabry disease in CKD patients not receiving renal replacement therapy. METHODS: This prospective study assessed α-galactosidase activity in dried blood spots in 313 stage 1-5 CKD patients, 167 males, between ages of 18-70 years whose etiology of CKD was unknown and were not receiving renal replacement therapy...
2016: Kidney & Blood Pressure Research
https://www.readbyqxmd.com/read/28001183/quality-of-life-in-hemodialysis-patients-and-the-relationship-with-mortality-hospitalizations-and-poor-treatment-adherence
#14
Araiê Prado Berger Oliveira, Debora Berger Schmidt, Thaís Malucelli Amatneeks, Jéssica Caroline Dos Santos, Luiza Helena Raittz Cavallet, Renate Brigitte Michel
INTRODUCTION: Chronic kidney disease (CKD) causes sudden changes in the daily lives of patients, creates limitations to perform activities of daily life and creates a great impact on emotions and quality of life (QOL) of patients. OBJECTIVE: To understand the relationship between QOL of patients on dialysis and mortality rates, hospitalization and absences. METHODS: A prospective descriptive study with 286 patients on hemodialysis, by applying demographic questionnaire, KDQOL SF-36 and electronic medical record analysis Dialsist...
December 2016: Jornal Brasileiro de Nefrologia: ʹorgão Oficial de Sociedades Brasileira e Latino-Americana de Nefrologia
https://www.readbyqxmd.com/read/27990732/symptoms-among-patients-receiving-in-center-hemodialysis-a-qualitative-study
#15
Kim J Cox, Mark B Parshall, Stephen H A Hernandez, Sanah Z Parvez, Mark L Unruh
Introduction Assessment of dialysis-related symptoms is not currently a requirement for hemodialysis (HD) providers in the United States. The purpose of this study was to describe patients' perspectives on symptoms associated with end-stage chronic kidney disease treated with thrice-weekly, in-center HD. Methods We performed a qualitative study using interpretive description. Interview questions were based on a KDIGO (Kidney Disease Improving Global Outcomes) controversies conference and a literature review...
December 19, 2016: Hemodialysis International
https://www.readbyqxmd.com/read/27863777/concentration-of-serum-calcium-is-not-correlated-with-symptoms-or-severity-of-primary-hyperparathyroidism-an-examination-of-20-081-consecutive-adults
#16
Deva Boone, Douglas Politz, Jose Lopez, Jamie Mitchell, Kevin Parrack, James Norman
BACKGROUND: Guidelines for operative treatment of primary hyperparathyroidism include calcium levels >1 mg/dL above normal. We sought to determine whether greater calcium concentrations were associated with increased symptoms or disease severity. METHODS: A retrospective review of a prospectively maintained database of adults undergoing parathyroidectomy for primary hyperparathyroidism, grouped according to greatest preoperative calcium level: those patients with calcium concentrations between 10...
January 2017: Surgery
https://www.readbyqxmd.com/read/27819409/interventions-for-chronic-kidney-disease-associated-restless-legs-syndrome
#17
REVIEW
Seerapani Gopaluni, Mohamed Sherif, Naim A Ahmadouk
BACKGROUND: Restless legs syndrome (RLS) is defined as the spontaneous movement of the limbs (mainly legs) associated with unpleasant, sometimes painful sensation which is relieved by moving the affected limb. Prevalence of RLS among people on dialysis has been estimated between 6.6% and 80%. RLS symptoms contribute to impaired quality of life and people with RLS are shown to have increased cardiovascular morbidity and mortality.Various pharmacological and non-pharmacological interventions have been used to treat primary RLS...
November 7, 2016: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/27760547/secondary-bladder-amyloidosis-with-familial-mediterranean-fever-in-a-living-donor-kidney-transplant-recipient-a-case-report
#18
Sentaro Imamura, Shintaro Narita, Ryuta Nishikomori, Hiroshi Tsuruta, Kazuyuki Numakura, Atsushi Maeno, Mitsuru Saito, Takamitsu Inoue, Norihiko Tsuchiya, Hiroshi Nanjo, Toshio Heike, Shigeru Satoh, Tomonori Habuchi
BACKGROUND: Secondary bladder amyloidosis is an extremely rare disease, resulting from a chronic systematic inflammatory disorder associated with amyloid deposits. Although uncommon in Japan, familial Mediterranean fever (FMF) is a hereditary autoinflammatory disease characterized by recurrent episodes of fever of short duration and serositis and is frequently associated with systemic amyloidosis. Here, we present a case of a Japanese patient complaining of fever and macroscopic hematuria after a living donor renal transplantation...
October 19, 2016: BMC Research Notes
https://www.readbyqxmd.com/read/27747026/emerging-co-morbidities-of-obstructive-sleep-apnea-cognition-kidney-disease-and-cancer
#19
REVIEW
Nadia Gildeh, Panagis Drakatos, Sean Higgins, Ivana Rosenzweig, Brian D Kent
Obstructive sleep apnea (OSA) causes daytime fatigue and sleepiness, and has an established relationship with cardiovascular and metabolic disease. Recent years have seen the emergence of an evidence base linking OSA with an increased risk of degenerative neurological disease and associated cognitive impairment, an accelerated rate of decline in kidney function with an increased risk of clinically significant chronic kidney disease (CKD), and with a significantly higher rate of cancer incidence and death. This review evaluates the evidence base linking OSA with these seemingly unrelated co-morbidities, and explores potential mechanistic links underpinning their development in patients with OSA, including intermittent hypoxia (IH), sleep fragmentation, sympathetic excitation, and immune dysregulation...
September 2016: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/27586847/gonadal-dysfunction-in-chronic-kidney-disease
#20
REVIEW
Biff F Palmer, Deborah J Clegg
Sexual dysfunction is a common finding in both men and women with chronic kidney failure. Common disturbances include erectile dysfunction in men, menstrual abnormalities in women, and decreased libido and fertility in both sexes. These abnormalities are primarily organic in nature and are related to uremia as well as the other comorbid conditions that frequently occur in the chronic kidney failure patient. Fatigue and psycho social factors related to the presence of a chronic disease are also contributory factors...
March 2017: Reviews in Endocrine & Metabolic Disorders
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