Use the keywords feature with a free QxMD account.
Use Read by QxMD to access full text via your institution or open access sources.
Read also provides personalized recommendations to keep you up to date in your field.
Existing User
Sign InNew to Read
Sign Up#21
JOURNAL ARTICLE
Sara Jambarsang, Moslem Taheri Soodejani, Robert Tate, Reyhane Sefidkar
BACKGROUND AND AIMS: Hypertension is the leading preventable risk factor for cardiovascular disease, chronic kidney disease and cognitive impairment, and mortality and disability worldwide. Since prevention, early detection, and treatment of blood pressure improve public health, the aim of present study was to determine the best obesity indices and estimate the optimal cut-off point for each one to predict the risk of elevated/stage 1 and undiagnosed hypertension in the population of center of Iran based on American ACC/AHA 2020 guidelines...
February 2024: Health Science Reports
#22
JOURNAL ARTICLE
Claudio A Dávila-Cervantes, Marcela Agudelo-Botero
OBJECTIVE: To report the burden of young-onset chronic kidney disease (CKD) in Mexico from 1990 to 2019, and to assess the association between young-onset CKD burden with the Socio-Demographic Index (SDI), and the Healthcare Access and Quality Index (HAQ). METHODS: Secondary analysis of data using the Global Burden of Disease, Injuries, and Risk Factors Study (GBD) by sex, age groups, states, and subcauses. Mortality, years of life lost (YLL), years lived with disability (YLD), and disability-adjusted life years (DALY), were obtained...
February 20, 2024: Preventive Medicine
#23
REVIEW
K Ramya, D Jagadeswaran
Chronic kidney disease is a universal topic gravitating towards various aspects of widespread illness, impacting the overall well-being of human beings. Patients with longstanding renal complaints under dialysis encounter challenges correlated with physical, intuitive, and socio-economic conditions to a greater extent in their daily existence. These portions may include changes in the appearance of a person, restricted physique movements, curbed diet, duration of surgical protocols, travelling time during the period of prevention, financial load, role reversal in the family followed by ruining their livelihood, deprived social rank, difficulty in relational, cordial relationships, and so on...
February 2024: Curēus
#24
JOURNAL ARTICLE
Jacek A Kopec, Farshad Pourmalek, Daniel A Adeyinka, Amin Adibi, Gina Agarwal, Samiah Alam, Zulfiqar A Bhutta, Zahid A Butt, Vijay K Chattu, Oghenowede Eyawo, Ghazal Fazli, Seyed-Mohammad Fereshtehnejad, Jeffrey J Hebert, Md Belal Hossain, Marcus M Ilesanmi, Ademola J Itiola, Haitham Jahrami, Niranjan Kissoon, Barthelemy K Defo, Om P Kurmi, Ali H Mokdad, Christopher J L Murray, Andrew T Olagunju, Seithikurippu R Pandi-Perumal, Scott B Patten, Ata Rafiee, Drona Prakash Rasali, Yaeesh Sardiwalla, Thirunavukkarasu Sathish, Marco Solmi, Ranjani Somayaji, Saverio Stranges, Marcello Tonelli, Ziyue Wang, Sanni Yaya, Frank J Elgar
OBJECTIVE: Monitoring trends in key population health indicators is important for informing health policies. The aim of this study was to examine population health trends in Canada over the past 30 years in relation to other countries. METHODS: We used data on disability-adjusted life years (DALYs), years of life lost (YLL), years lived with disability, life expectancy (LE), and child mortality for Canada and other countries between 1990 and 2019 provided by the Global Burden of Disease Study...
February 15, 2024: Canadian Journal of Public Health. Revue Canadienne de Santé Publique
#25
Charisse Madlock-Brown, Austen Lee, Jaime Seltzer, Anthony Solomonides, Nisha Mathews, Jimmy Phuong, Nicole Weiskopf, William G Adams, Harold Lehmann, Juan Espinoza
Background: This research delves into the confluence of racial disparities and health inequities among individuals with disabilities, with a focus on those contending with both diabetes and visual impairment. Methods: Utilizing data from the TriNetX Research Network, which includes electronic medical records of roughly 115 million patients from 83 anonymous healthcare organizations, this study employs a directed acyclic graph (DAG) to pinpoint confounders and augment interpretation. We identified patients with visual impairments using ICD-10 codes, deliberately excluding diabetes-related ophthalmology complications...
January 30, 2024: Research Square
#26
REVIEW
Barıs Mulla Cetin, Fatma Betul Guzel, Ilyas Ozturk, Ertugrul Erken, Ozkan Gungor, Orcun Altunoren
OBJECTIVE: Uremic pruritus is a distressing complication of chronic kidney disease (CKD), associated with mortality, and negatively impacts quality of life. The 5D-Itch Scale (5D-IS) is an easy-to-apply technique that evaluates 5 different dimensions of itching such as duration, severity, course, disability, and prevalence. We aimed to investigate the prevalence of itching in different CKD stages using the 5D-IS and to investigate the factors associated with itching in CKD patients. MATERIALS AND METHODS: 5D-IS was used to evaluate itching in chronic hemodialysis (HD) and Stage 3-5 CKD patients...
February 9, 2024: International Urology and Nephrology
#27
JOURNAL ARTICLE
Marco Egle, Wei-Chun Wang, Yang C Fann, Michelle C Johansen, Jiunn-Tay Lee, Chung-Hsin Yeh, Chih-Hao Jason Lin, Jiann-Shing Jeng, Yu Sun, Li-Ming Lien, Rebecca F Gottesman
BACKGROUND AND OBJECTIVES: Multimorbidity is common in patients who experience stroke. Less is known about the effect of specific multimorbidity patterns on long-term disability in patients with stroke. Furthermore, given the increased poststroke disability frequently seen in female vs male patients, it is unknown whether multimorbidity has a similar association with disability in both sexes. We assessed whether specific multimorbidity clusters were associated with greater long-term poststroke disability burden overall and by sex...
March 12, 2024: Neurology
#28
JOURNAL ARTICLE
Erum Shariff, Saima Nazish, Azra Zafar, Rizwana Shahid, Norah A AlKhaldi, Modhi Saad A Alkhaldi, Danah AlJaafari, Nehad M Soltan, Mohammed AlShurem, Aishah Ibrahim Albakr, Feras AlSulaiman, Majed Alabdali
Objective: Post-stroke seizures (PSS) are one of the major stroke-related complications. Early therapeutic interventions are critical therefore using electroencephalography (EEG) as a predictive tool for future recurrence may be helpful. We aimed to assess frequencies of different EEG patterns in patients with PSS and their association with seizure recurrence and functional outcomes. Methods: All patients admitted with PSS were included and underwent interictal EEG recording during their admission and monitored for seizure recurrence for 24 months...
February 6, 2024: Clinical EEG and Neuroscience: Official Journal of the EEG and Clinical Neuroscience Society (ENCS)
#29
JOURNAL ARTICLE
Fuhmei Wang, Jing-Shiang Hwang, Wen-Yen Huang, Yu-Tzu Chang, Jung-Der Wang
OBJECTIVE: Studies that examine the broad allocation of resources, regardless of who bears the costs, should ideally estimate costs from a societal perspective. We have successfully integrated survival rates, employment ratios, and earnings to address the significant challenge of evaluating societal value through productivity assessments of patients with end-stage kidney disease (ESKD) in Taiwan. METHODS: Using a theoretical framework, we interconnected two nationwide databases: the Taiwan National Health Insurance (NHI) and the Taiwan Mortality Registry from 2000 to 2017...
February 6, 2024: Health Economics Review
#30
JOURNAL ARTICLE
Antoine Lanot, Laurent Misery, Guy Rostoker, Angelo Testa, Philippe Chauveau, Maxime Touzot, Nans Florens, Pierre Bataille
Chronic kidney disease-associated pruritus (CKD-aP) is a disabling symptom which is frequent and often underestimated. Pa-MRC has a negative impact on quality of life, and is frequently accompanied by sleep disorders and depression. The approval of difelikefalin – a kappa opioid receptor agonist – in this indication requires updated recommendations. As a first step, secondary causes of pruritus without skin lesions must be ruled out, and general measures taken (emollients, psychological support, optimization of dialysis, normalization of serum calcium, phosphate and PTH in the range proposed by the KGIDO guidelines, treatment of iron deficiency)...
January 31, 2024: Néphrologie & Thérapeutique
#31
JOURNAL ARTICLE
Mohammad-Mahdi Rashidi, Sahar Saeedi Moghaddam, Sina Azadnajafabad, Esmaeil Mohammadi, Amirmohammad Khalaji, Mohammad-Reza Malekpour, Mohammad Keykhaei, Negar Rezaei, Zahra Esfahani, Nazila Rezaei, Ali H Mokdad, Christopher J L Murray, Mohsen Naghavi, Bagher Larijani, Farshad Farzadfar
BACKGROUND: The study aimed to estimate the attributable burden to kidney dysfunction as a metabolic risk factor in the North Africa and Middle East (NAME) region and its 21 countries in 1990-2019. METHODS: The data used in this study were obtained from the Global Burden of Diseases (GBD) 2019 study, which provided estimated measures of deaths, disability-adjusted life years (DALYs), and other epidemiological indicators of burden. To provide a better insight into the differences in the level of social, cultural, and economic factors, the Socio-Demographic Index (SDI) was used...
January 2024: Clinical Kidney Journal
#32
REVIEW
Dina Greenberg, Norman D Rosenblum, Marcello Tonelli
Hearing loss affects nearly 1.6 billion people and is the third-leading cause of disability worldwide. Chronic kidney disease (CKD) is also a common condition that is associated with adverse clinical outcomes and high health-care costs. From a developmental perspective, the structures responsible for hearing have a common morphogenetic origin with the kidney, and genetic abnormalities that cause familial forms of hearing loss can also lead to kidney disease. On a cellular level, normal kidney and cochlea function both depend on cilial activities at the apical surface, and kidney tubular cells and sensory epithelial cells of the inner ear use similar transport mechanisms to modify luminal fluid...
January 29, 2024: Nature Reviews. Nephrology
#33
JOURNAL ARTICLE
Isobel L Ward, Chris Robertson, Utkarsh Agrawal, Lynsey Patterson, Declan T Bradley, Ting Shi, Simon de Lusignan, F D Richard Hobbs, Aziz Sheikh, Vahé Nafilyan
The emergence of the COVID-19 vaccination has been critical in changing the course of the COVID-19 pandemic. To ensure protection remains high in vulnerable groups booster vaccinations in the UK have been targeted based on age and clinical vulnerabilities. We undertook a national retrospective cohort study using data from the 2021 Census linked to electronic health records. We fitted cause-specific Cox models to examine the association between health conditions and the risk of COVID-19 death and all-other-cause death for adults aged 50-100-years in England vaccinated with a booster in autumn 2022...
January 16, 2024: Nature Communications
#34
JOURNAL ARTICLE
Hui Huang, Zhengqiu Zhu, Han Wang, Xuehui Ma, Wenjun Liu, Yiyun Wu, Chong Zou, Yinping Wang, Bixiao Shen, Weiming Ge, Hui Gao, Yun Luan, Xuezhong Jiang
BACKGROUND: The mortality and disability of chronic kidney disease (CKD) are highly linked to the incidence of atherosclerotic cardiovascular events. Numerous clinical biochemical indicators of renal function often only increase in advanced stages of CKD, driving an urgent need for reliable indicators of atherosclerosis in early CKD. Ultrafast pulse wave velocity (ufPWV) can evaluate the stiffness of the straight carotid in vivo and quantitatively reflect the degree of early atherosclerosis...
January 3, 2024: Quantitative Imaging in Medicine and Surgery
#35
JOURNAL ARTICLE
Tetsuya Takahashi, Kentaro Iwata, Tomoyuki Morisawa, Michitaka Kato, Yuji Kono, Masanobu Taya, Yuki Iida, Yoshinari Funami, Kentaro Kamiya, Koji Sakurada, Masakazu Saitoh
BACKGROUND: This study determined the incidence of hospitalization-associated disability (HAD) and its characteristics in older patients with heart failure in Japan.Methods and Results: Ninety-six institutions participated in this nationwide multicenter registry study (J-Proof HF). From December 2020 to March 2022, consecutive heart failure patients aged ≥65 years who were prescribed physical rehabilitation during hospitalization were enrolled. Of the 9,403 patients enrolled (median age 83...
January 13, 2024: Circulation Journal: Official Journal of the Japanese Circulation Society
#36
REVIEW
Ifeoma I Ulasi, Emmanuel A Burdmann, Chinwuba K Ijoma, Li-Fang Chou, Chih-Wei Yang
Individuals, societies, and the environment are affected by neglected and emerging diseases. These diseases result in a variety of severe outcomes, including permanent disabilities, chronic diseases such as chronic kidney disease, and even mortality. Consequences include high health care expenditures, loss of means of support, social stigma, and social exclusion. The burden of these diseases is exacerbated in low- and middle-income countries owing to poverty, inadequate fundamental infrastructure, and the absence of health and social protection systems...
January 11, 2024: Seminars in Nephrology
#37
REVIEW
Jared M Gollie, Alice S Ryan, Sabyasachi Sen, Samir S Patel, Peter F Kokkinos, Michael O Harris-Love, Joel D Scholten, Marc R Blackman
Chronic kidney disease (CKD) is among the leading causes of death and disability in the United States, affecting an estimated 800 million adults globally. The underlying pathophysiology of CKD is complex creating challenges to its management. Primary risk factors for the development and progression of CKD include diabetes mellitus, hypertension, age, obesity, diet, inflammation, and physical inactivity. The high prevalence of diabetes and hypertension in patients with CKD increases the risk for secondary consequences such as cardiovascular disease and peripheral neuropathy...
January 11, 2024: American Journal of Physiology. Renal Physiology
#38
REVIEW
Giuseppina Biondi, Nicola Marrano, Anna Borrelli, Martina Rella, Rossella D'Oria, Valentina Annamaria Genchi, Cristina Caccioppoli, Angelo Cignarelli, Sebastio Perrini, Luigi Laviola, Francesco Giorgino, Annalisa Natalicchio
Diabetes mellitus is a chronic metabolic disease, the prevalence of which is constantly increasing worldwide. It is often burdened by disabling comorbidities that reduce the quality and expectancy of life of the affected individuals. The traditional complications of diabetes are generally described as macrovascular complications (e.g., coronary heart disease, peripheral arterial disease, and stroke), and microvascular complications (e.g., diabetic kidney disease, retinopathy, and neuropathy). Recently, due to advances in diabetes management and the increased life expectancy of diabetic patients, a strong correlation between diabetes and other pathological conditions (such as liver diseases, cancer, neurodegenerative diseases, cognitive impairments, and sleep disorders) has emerged...
December 20, 2023: International Journal of Molecular Sciences
#39
JOURNAL ARTICLE
Xiaomin Zhong, Diane Ashiru-Oredope, Alexander Pate, Glen P Martin, Anita Sharma, Paul Dark, Tim Felton, Claire Lake, Brian MacKenna, Amir Mehrkar, Sebastian C J Bacon, Jon Massey, Peter Inglesby, Ben Goldacre, Kieran Hand, Sian Bladon, Neil Cunningham, Ellie Gilham, Colin S Brown, Mariyam Mirfenderesky, Victoria Palin, Tjeerd Pieter van Staa
BACKGROUND: Sepsis, characterised by significant morbidity and mortality, is intricately linked to socioeconomic disparities and pre-admission clinical histories. This study aspires to elucidate the association between non-COVID-19 related sepsis and health inequality risk factors amidst the pandemic in England, with a secondary focus on their association with 30-day sepsis mortality. METHODS: With the approval of NHS England, we harnessed the OpenSAFELY platform to execute a cohort study and a 1:6 matched case-control study...
December 2023: EClinicalMedicine
#40
JOURNAL ARTICLE
Odessica Hughes, Amy R Bentley, Charles E Breeze, Francois Aguet, Xiaoguang Xu, Girish Nadkarni, Quan Sun, Bridget M Lin, Thomas Gilliland, Mariah C Meyer, Jiawen Du, Laura M Raffield, Holly Kramer, Robert W Morton, Mateus H Gouveia, Elizabeth G Atkinson, Adan Valladares-Salgado, Niels Wacher-Rodarte, Nicole D Dueker, Xiuqing Guo, Yang Hai, Adebowale Adeyemo, Lyle G Best, Jianwen Cai, Guanjie Chen, Michael Chong, Ayo Doumatey, James Eales, Mark O Goodarzi, Eli Ipp, Marguerite Ryan Irvin, Minzhi Jiang, Alana C Jones, Charles Kooperberg, Jose E Krieger, Ethan M Lange, Matthew B Lanktree, James P Lash, Paulo A Lotufo, Ruth J F Loos, Vy Thi Ha My, Jesús Peralta-Romero, Lihong Qi, Leslie J Raffel, Stephen S Rich, Erik J Rodriquez, Eduardo Tarazona-Santos, Kent D Taylor, Jason G Umans, Jia Wen, Bessie A Young, Zhi Yu, Ying Zhang, Yii-Der Ida Chen, Tanja Rundek, Jerome I Rotter, Miguel Cruz, Myriam Fornage, Maria Fernanda Lima-Costa, Alexandre C Pereira, Guillaume Paré, Pradeep Natarajan, Shelley A Cole, April P Carson, Leslie A Lange, Yun Li, Eliseo J Perez-Stable, Ron Do, Fadi J Charchar, Maciej Tomaszewski, Josyf C Mychaleckyj, Charles Rotimi, Andrew P Morris, Nora Franceschini
Chronic kidney disease is a leading cause of death and disability globally and impacts individuals of African ancestry (AFR) or with ancestry in the Americas (AMS) who are under-represented in genome-wide association studies (GWASs) of kidney function. To address this bias, we conducted a large meta-analysis of GWASs of estimated glomerular filtration rate (eGFR) in 145,732 AFR and AMS individuals. We identified 41 loci at genome-wide significance (p < 5 × 10-8 ), of which two have not been previously reported in any ancestry group...
December 20, 2023: Cell Genom
Make the most of Read.
Download the mobile app.
Download the mobile app.
Fetching more papers... 
