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https://www.readbyqxmd.com/read/28453810/ecomment-the-thoracic-aorta-as-an-antegrade-inflow-source-for-chronic-mesenteric-ischaemia
#1
Nicolas J Mouawad
No abstract text is available yet for this article.
May 1, 2017: Interactive Cardiovascular and Thoracic Surgery
https://www.readbyqxmd.com/read/28453794/blood-flow-competition-after-aortic-valve-bypass-an-evaluation-using-computational-fluid-dynamics
#2
Koji Kawahito, Naoyuki Kimura, Kenji Komiya, Masanori Nakamura, Yoshio Misawa
OBJECTIVES: Aortic valve bypass (AVB) (apico-aortic conduit) remains an effective surgical alternative for patients in whom surgical aortic valve replacement or transcatheter aortic valve implantation is not feasible. However, specific complications include thrombus formation, possibly caused by stagnation arising from flow competition between the antegrade and retrograde flow, but this has not been fully investigated. The aim of this study was to analyse flow characteristics after AVB and to elucidate mechanisms of intra-aortic thrombus using computational fluid dynamics (CFD)...
May 1, 2017: Interactive Cardiovascular and Thoracic Surgery
https://www.readbyqxmd.com/read/28453577/abdominal-aortic-aneurysm-screening-program-using-hand-held-ultrasound-in-primary-healthcare
#3
Antoni Sisó-Almirall, Belchin Kostov, Marta Navarro González, Daniel Cararach Salami, Alfonso Pérez Jiménez, Rosa Gilabert Solé, Concepció Bru Saumell, Lluís Donoso Bach, Mireia Villalta Martí, Luis González-de Paz, Rafael Ruiz Riera, Vicenç Riambau Alonso, Nihan Acar-Denizli, Marta Farré Almacellas, Manuel Ramos-Casals, Jaume Benavent Àreu
We determined the feasibility of abdominal aortic aneurysm (AAA) screening program led by family physicians in public primary healthcare setting using hand-held ultrasound device. The potential study population was 11,214 men aged ≥ 60 years attended by three urban, public primary healthcare centers. Participants were recruited by randomly-selected telephone calls. Ultrasound examinations were performed by four trained family physicians with a hand-held ultrasound device (Vscan®). AAA observed were verified by confirmatory imaging using standard ultrasound or computed tomography...
2017: PloS One
https://www.readbyqxmd.com/read/28449459/endovascular-repair-of-residual-intimal-tear-or-distal-new-entry-after-frozen-elephant-trunk-for-type-a-aortic-dissection
#4
Xu-Dong Pan, Bin Li, Wei-Guo Ma, Jun Zheng, Yong-Min Liu, Jun-Ming Zhu, Lian-Jun Huang, Li-Zhong Sun
BACKGROUND: In patients with type A dissection, residual dissection and new distal entry tears following the frozen elephant trunk (FET) procedure adversely affect long-term prognosis. Management include open and endovascular repair, while clinical experience is limited. We evaluate the efficacy of thoracic endovascular aortic repair (TEVAR) in management of residual intimal tear or distal new entry tear following FET in patients with type A aortic dissection (TAAD). METHODS: Between May 2003 and April 2013, we performed FET and total arch replacement for 1,003 patients with TAAD...
March 2017: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/28449316/does-my-high-blood-pressure-improve-your-survival-overall-and-subgroup-learning-curves-in-health
#5
Raf Van Gestel, Tobias Müller, Johan Bosmans
Learning curves in health are of interest for a wide range of medical disciplines, healthcare providers, and policy makers. In this paper, we distinguish between three types of learning when identifying overall learning curves: economies of scale, learning from cumulative experience, and human capital depreciation. In addition, we approach the question of how treating more patients with specific characteristics predicts provider performance. To soften collinearity problems, we explore the use of least absolute shrinkage and selection operator regression as a variable selection method and Theil-Goldberger mixed estimation to augment the available information...
April 27, 2017: Health Economics
https://www.readbyqxmd.com/read/28449058/corrigendum-to-diagnosis-and-management-of-acute-deep-vein-thrombosis-a-joint-consensus-document-from-the-european-society-of-cardiology-working-groups-of-aorta-and-peripheral-circulation-and-pulmonary-circulation-and-right-ventricular-function-eur-heart-j
#6
https://www.readbyqxmd.com/read/28448973/downregulations-of-cd36-and-calpain-1-inflammation-and-atherosclerosis-by-simvastatin-in-apolipoprotein-e-knockout-mice
#7
Meihui Yin, Qianqian Liu, Lan Yu, Yueyan Yang, Meili Lu, Hongxin Wang, Duosheng Luo, Xianglu Rong, Futian Tang, Jiao Guo
BACKGROUND: In the previous in vitro study, we found that simvastatin decreased the protein expression of CD36, the scavenger receptor, and calpain-1, the Ca2+-sensitive cysteine protease, in oxidized low-density lipoprotein (oxLDL)-treated macrophages. In this in vivo study, we investigated whether simvastatin downregulates the expression of CD36 and calpain-1 and inhibits the inflammation and atherosclerosis in apolipoprotein E knockout (ApoE KO) mice. METHODS: Twenty male 6-week-old ApoE KO mice were divided into 2 groups: the ApoE KO group and the ApoE KO + simvastatin (ApoE KO + Sim) group...
April 28, 2017: Journal of Vascular Research
https://www.readbyqxmd.com/read/28448522/nestin-expression-is-upregulated-in-the-fibrotic-rat-heart-and-is-localized-in-collagen-expressing-mesenchymal-cells-and-interstitial-cd31-cells
#8
Vanessa Hertig, Kim Tardif, Marc Andre Meus, Natacha Duquette, Louis Villeneuve, Fanny Toussaint, Jonathan Ledoux, Angelino Calderone
Renal and lung fibrosis was characterized by the accumulation of collagen-immunoreactive mesenchymal cells expressing the intermediate filament protein nestin. The present study tested the hypothesis that nestin expression was increased in the hypertrophied/fibrotic left ventricle of suprarenal abdominal aorta constricted adult male Sprague-Dawley rats and induced in ventricular fibroblasts by pro-fibrotic peptide growth factors. Nestin protein levels were upregulated in the pressure-overloaded left ventricle and expression positively correlated with the rise of mean arterial pressure...
2017: PloS One
https://www.readbyqxmd.com/read/28448412/optimizing-contrast-media-injection-protocols-in-computed-tomography-angiography-at-different-tube-voltages-evaluation-in-a-circulation-phantom
#9
Damiano Caruso, Marwen Eid, U Joseph Schoepf, Domenico De Santis, Akos Varga-Szemes, Stefanie Mangold, Christian Canstein, Virginia W Lesslie, Stephen R Fuller, B Devon Ball, Andrea Laghi, Carlo N De Cecco
OBJECTIVES: The aim of this study was to investigate the minimum iodine delivery rate (IDR) and contrast media (CM) volume required for diagnostic contrast enhancement of 350 HU (Hounsfield units) in the ascending aorta at different kV settings. METHODS: Dynamic computed tomography acquisitions from 70 to 150 kV were performed in a circulation phantom. First, injections with IDR ranging from 0.1 to 2.0 g I/s were tested for each kV. In the second part, the IDR was held constant, whereas the CM volume was reduced from 50 to 10 mL...
April 26, 2017: Journal of Computer Assisted Tomography
https://www.readbyqxmd.com/read/28448402/left-atrium-measurements-via-computed-tomography-pulmonary-angiogram-as-a-predictor-of-diastolic-dysfunction
#10
Adam N Lick, Raman Danrad, David L Smith, Matthew R Lammi
PURPOSE: Left atrium (LA) enlargement on echocardiography may be an indicator of diastolic dysfunction (DD). It is not well known if computed tomography pulmonary angiography (CTPA) can detect DD. METHODS: A total of 127 patients who underwent both CTPA and echo within 48 hours were analyzed retrospectively. Left atrium diameters from CTPA were correlated with echo and evaluated against degrees of DD. Computed tomography pulmonary angiography pulmonary artery (PA)/aorta ratio was analyzed as a tool to detect pulmonary hypertension...
April 26, 2017: Journal of Computer Assisted Tomography
https://www.readbyqxmd.com/read/28448321/chest-pain-during-cesarean-delivery-in-relation-to-anomalous-right-coronary-artery-a-case-report
#11
Blanca Tapia Salinas, Andrea Kollmann Camaiora, Estibaliz Alsina Marcos, Fernando Gilsanz
Chest pain during labor can have many etiologies, one of which is myocardial ischemia. We report a 38-year-old woman with American Society of Anesthesiology physical status I scheduled for elective cesarean delivery who experienced chest pain and electrocardiographic signs of myocardial ischemia immediately after carbetocin administration. Subsequent investigations revealed an aberrant right coronary artery originating from the left coronary sinus coursing between the aorta and the pulmonary artery. This was considered the likely cause of the patient's chest pain...
April 26, 2017: A & A Case Reports
https://www.readbyqxmd.com/read/28448310/comparison-of-power-versus-manual-injection-in-bolus-shape-and-image-quality-on-contrast-enhanced-magnetic-resonance-angiography-an-experimental-study-in-a-swine-model
#12
Takahiro Tsuboyama, Gregor Jost, Hubertus Pietsch, Noriyuki Tomiyama
OBJECTIVE: The aim of this study was to compare power versus manual injection in bolus shape and image quality on contrast-enhanced magnetic resonance angiography (CE-MRA). MATERIALS AND METHODS: Three types of CE-MRA (head-neck 3-dimensional [3D] MRA with a test-bolus technique, thoracic-abdominal 3D MRA with a bolus-tracking technique, and thoracic-abdominal time-resolved 4-dimensional [4D] MRA) were performed after power and manual injection of gadobutrol (0...
April 26, 2017: Investigative Radiology
https://www.readbyqxmd.com/read/28448188/effects-of-indomethacin-on-prostanoid-synthesis-and-vasomotor-responsiveness-in-endothelium-denuded-abdominal-and-thoracic-aortas-of-wistar-rats
#13
Ruth M López, Janette E López, Jorge S López, María C Castillo, Gustavo Guevara, José A Morales, Oscar A López, Jair Lozano, Enrique F Castillo
In endothelium-denuded abdominal (but not thoracic) aortas of rats, the nonselective cyclooxygenase (COX) inhibitor, indomethacin, suppressed contractions evoked by α-adrenergic agonists hypothetically mediated by prostanoids. We aimed to identify these non-endothelial-derived contractile prostanoids released by α-adrenergic receptors activation. Endothelium-denuded abdominal and thoracic aortas of Wistar rats were used for biochemical and functional analyses. Western blot analysis showed that COX-1 and COX-2 protein levels were respectively equivalent in endothelium-denuded abdominal and thoracic aortas...
2017: Clinical and Experimental Hypertension: CHE
https://www.readbyqxmd.com/read/28447981/isolation-characterization-and-purification-of-macrophages-from-tissues-affected-by-obesity-related-inflammation
#14
Joselyn N Allen, Adwitia Dey, Ruth Nissly, James Fraser, Shan Yu, Gayathri Balandaram, Jeffrey M Peters, Pamela A Hankey-Giblin
Obesity promotes a chronic inflammatory state that is largely mediated by tissue-resident macrophages as well as monocyte-derived macrophages. Diet-induced obesity (DIO) is a valuable model in studying the role of macrophage heterogeneity; however, adequate macrophage isolations are difficult to acquire from inflamed tissues. In this protocol, we outline the isolation steps and necessary troubleshooting guidelines derived from our studies for obtaining a suitable population of tissue-resident macrophages from mice following 18 weeks of high-fat (HFD) or high-fat/high-cholesterol (HFHCD) diet intervention...
April 3, 2017: Journal of Visualized Experiments: JoVE
https://www.readbyqxmd.com/read/28447918/no-relation-between-biomarkers-at-age-47-49-and-aortic-diameter-after-14-19-years-of-follow-up-a-population-based-study
#15
Soumia Taimour, Moncef Zarrouk, Jan Holst, Olle Melander, Gunar Engström, J Gustav Smith, Anders Gottsäter
BACKGROUND: Biomarkers reflecting diverse pathophysiological pathways may play an important role in the pathogenesis of abdominal aortic aneurysm (aortic diameter ≥30 mm, AAA), levels of many biomarkers are elevated and correlated to aortic diameter among 65-year-old men undergoing ultrasound (US) screening for AAA. PROBANDS AND METHODS: To evaluate potential relationships between biomarkers and aortic dilatation after long-term follow-up, levels of C-reactive protein (CRP), proneurotensin (PNT), copeptin (CPT), lipoprotein-associated phospholipase 2 (Lp-PLA2), cystatin C (Cyst C), midregional proatrial natriuretic peptide (MR-proANP), and midregional proadrenomedullin (MR-proADM) were measured in 117 subjects (114 [97 %] men) aged 47-49 in a prospective population-based cohort study, and related to aortic diameter at US examination of the aorta after 14-19 years of follow-up...
April 27, 2017: VASA. Zeitschrift Für Gefässkrankheiten
https://www.readbyqxmd.com/read/28447279/multi-modality-molecular-imaging-of-aortic-aneurysms
#16
Brian J Malm, Mehran M Sadeghi
Aneurysms of the thoracic and abdominal aorta are common and can be associated with significant morbidity and mortality when complications, including dissection, rupture, or thrombosis, occur. Current approaches to diagnosis and risk stratification rely on measurements of aneurysm size and rate of growth, often using various imaging modalities, which may be suboptimal in identifying patients at the highest and lowest risk of complications. Targeting the biological processes underlying aneurysm formation and expansion with molecular imaging offers an exciting opportunity to characterize aortic aneurysms beyond size and address current gaps in our approach to diagnosis and treatment...
April 26, 2017: Journal of Nuclear Cardiology: Official Publication of the American Society of Nuclear Cardiology
https://www.readbyqxmd.com/read/28447108/split-bolus-intravenous-contrast-material-injection-vs-single-bolus-injection-in-patients-following-endovascular-abdominal-aortic-repair-evar
#17
Johannes Boos, Vassilios Raptopoulos, Alexander Brook, Olga R Brook
PURPOSE: To investigate the feasibility and accuracy of a split-bolus contrast injection CTA (SB-CTA) compared to a single-bolus injection CTA (SI-CTA) protocol of post-EVAR patients. MATERIALS AND METHODS: In this IRB-approved study, patients who underwent SB-CTA and SI-CTA after EVAR were evaluated. Attenuation and contrast-to-noise ratio (CNR) of vessels and parenchymal organs were assessed. Subjective enhancement of vessels, quality of 3D reconstructions, and enhancement phase of parenchymal organs were assessed by two independent readers...
April 26, 2017: Abdominal Radiology
https://www.readbyqxmd.com/read/28446857/hemolytic-anemia-caused-by-kinking-of-dacron-grafts-implanted-in-repair-of-after-aortic-dissection
#18
Feridoun Sabzi, Fahimeh Ghasemi, Atefeh Asadmobini
BACKGROUND: Hemolytic anemia caused by a kinked Dacron graft is a rare complication after repair of acute aortic dissection. We present a case of hemolytic anemia due to kinking of previously implanted Dacron graft for ascending aorta dissection treated by surgery and replaced with new Dacron. CASE DETAILS: We report a case of postoperative hemolytic anemia with kinking of the graft at the outer graft layer and intra luminal bulging of the inner graft. Postoperative computed tomography showed Dacron graft kinking at the mid part of the graft...
September 2016: Ethiopian Journal of Health Sciences
https://www.readbyqxmd.com/read/28446225/the-crosstalk-between-vascular-mscs-and-inflammatory-mediators-determines-the-pro-calcific-remodelling-of-human-atherosclerotic-aneurysm
#19
Carmen Ciavarella, Enrico Gallitto, Francesca Ricci, Marina Buzzi, Andrea Stella, Gianandrea Pasquinelli
BACKGROUND: Human mesenchymal stem cells (MSCs) possess well-known reparative abilities, but any defect of the immunomodulatory activity and/or the differentiation process may determine the development of human diseases, including those affecting the vascular wall. MSCs residing within the human aortic wall represent a potential cell mediator of atherosclerotic aneurysm development. METHODS: MSCs isolated from healthy and aneurysm aortas were characterized by flow cytometer and tested for differentiation properties...
April 26, 2017: Stem Cell Research & Therapy
https://www.readbyqxmd.com/read/28446074/open-repair-of-hepatic-artery-and-celiac-artery-aneurysms-in-a-patient-with-prior-aortic-dissection-with-an-iliac-to-hepatic-artery-bypass
#20
Seema Joshi, Moshe Halak, Arie Ariche, Daniel Silverberg
A 67-year-old male with a history of an aortic dissection was found to have a large hepatic and celiac artery aneurysm. Due to the extent of the dissection within the aorta, a bypass was performed from his iliac artery to the hepatic bifurcation, followed by exclusion and ligation of the aneurysms.
January 1, 2017: Vascular and Endovascular Surgery
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