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Venous leg ulcers

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https://www.readbyqxmd.com/read/28640730/treating-patients-with-venous-leg-ulcers-in-the-acute-setting-part-1
#1
Irene Anderson
Leg ulcers present with a variety of aetiologies, sometimes in combination. The most common aetiology is venous, with treament involving compression, elevation and exercise; the most common treatment setting is the community. However, people with leg ulcers do sometimes require admission to hospital for conditions and situations which may, or may not, be ulcer-related. There is a lack of contemporary evidence on the experience of inpatients and insufficient analysis of the impact on healing and complications to the lower limb when patients with leg ulcers and compression therapy are admitted to hospital...
June 22, 2017: British Journal of Nursing: BJN
https://www.readbyqxmd.com/read/28638953/-chronic-leg-ulcers
#2
REVIEW
J Dissemond
Chronic wounds often manifest as ulcers on the lower legs. The main causes of chronic leg ulcers are chronic venous insufficiency and/or peripheral arterial occlusive disease in approximately 80% of all patients. However, there are also numerous other potentially relevant factors which can cause or almost impede the healing of chronic leg ulcers. Therefore, disease such as vasculitis, livedo vasculopathy, pyoderma gangrenosum, necrobiosis lipoidica, Martorell hypertensive leg ulcer, calciphylaxis, infectious diseases, neoplasms, drugs, cutaneous artefacts and genetic defects are exemplarily presented...
June 21, 2017: Der Hautarzt; Zeitschrift Für Dermatologie, Venerologie, und Verwandte Gebiete
https://www.readbyqxmd.com/read/28623990/incidence-of-venous-leg-ulcer-healing-and-recurrence-after-treatment-with-endovenous-laser-ablation
#3
William A Marston, Jason Crowner, Ana Kouri, Corey A Kalbaugh
BACKGROUND: The Effect of Surgery and Compression on Healing and Recurrence (ESCHAR) trial previously reported that patients with venous leg ulcers treated with saphenous stripping experienced a significantly reduced incidence of ulcer recurrence compared with patients treated with compression therapy. Most patients with leg ulcers and saphenous insufficiency are currently treated with endovenous thermal ablation (EVTA), but little information is available on the long-term results after EVTA in Clinical, Etiology, Anatomy, and Pathophysiology (CEAP) clinical class 5 (C5) and class 6 (C6) patients...
July 2017: Journal of Vascular Surgery. Venous and Lymphatic Disorders
https://www.readbyqxmd.com/read/28619238/mesenchymal-stem-cell-in-venous-leg-ulcer-an-intoxicating-therapy
#4
REVIEW
Anjali Athanerey, Pradeep Kumar Patra, Awanish Kumar
Venous leg ulcers (VLU) are a prevalent and reoccurring type of complicated wound, turning as a considerable public healthcare issue, with critical social and economic concern. There are both medical and surgical therapies to treat venous leg ulcers; however, a cure does not yet exist. Mesenchymal stem cells (MSC) are capable and proved of accelerating wound healing in vivo and their study with human chronic wounds is currently awaited. MSCs are a promising source of adult progenitor cells for cellular therapy and have been demonstrated to differentiate into various mesenchymal cell lineages...
June 7, 2017: Journal of Tissue Viability
https://www.readbyqxmd.com/read/28602045/compression-therapy-for-venous-leg-ulcers-risk-factors-for-adverse-events-and-complications-contraindications-a-review-of-present-guidelines
#5
A Andriessen, J Apelqvist, G Mosti, H Partsch, C Gonska, M Abel
INTRODUCTION: The adequate use of compression in venous leg ulcer treatment is equally important to patients as well as clinicians. Currently there is a lack of clarity on contra-indications, risk factors, adverse events and complications, when applying compression therapy for venous leg ulcer patients. METHODS: The project aimed to optimize prevention, treatment and maintenance approaches by recognizing contra-indications, risk factors, adverse events and complications, when applying compression therapy for venous leg ulcer patients...
June 11, 2017: Journal of the European Academy of Dermatology and Venereology: JEADV
https://www.readbyqxmd.com/read/28598763/chronic-venous-disease-and-wound-infection-approaches-prevention-and-outcome-measures-from-ewma
#6
Camila Fronzo
In May, BSN medical hosted two clinical symposia at the 2017 EWMA conference. These described the challenges in reducing the costs of treatment for patients with chronic venous disease (CVD), the importance of compression therapy and physical activity in the management and prevention of leg ulcers, and the obstacles in treating wound infection, among other topics. Camila Fronzo, JWC chief sub editor, was there to summarise the main points of each session.
June 2, 2017: Journal of Wound Care
https://www.readbyqxmd.com/read/28598757/exudates-absorption-and-proteases-trapping-in-venous-leg-ulcers
#7
P Humbert, C Courderot-Masuyer, S Robin, D Oster, R Pegahi
OBJECTIVE: In venous leg ulcer (VLU), the impaired healing has been shown to be associated with excessive levels of protease activities such as matrix metalloproteinases (MMPs) and elastases found in exudates. The present study focused on exudates absorption and proteases trapping capacity of a new generation of polyacrylate superabsorbent, Tegaderm superabsorber (TS), compared with a traditional dressing such as Zetuvit. METHOD: We studied the proteases implicated in VLU (MMP-1, MMP-2, MMP-9 and PMN elastase)...
June 2, 2017: Journal of Wound Care
https://www.readbyqxmd.com/read/28577056/-specific-indications-for-foam-sclerotherapy
#8
REVIEW
B Kahle
BACKGROUND: Foam sclerotherapy is well established in the treatment of varicose veins of different sizes. METHODS: A literature review was performed to determine which specific indications for foam sclerotherapy exist. RESULTS: Treatment of venous leg ulcers, varices that might rupture, varicose veins in geriatric patients, pudendal veins and seroma could be determined as specific indications for foam sclerotherapy. CONCLUSION: In some indications, foam sclerotherapy is the treatment option of first choice...
June 2, 2017: Der Hautarzt; Zeitschrift Für Dermatologie, Venerologie, und Verwandte Gebiete
https://www.readbyqxmd.com/read/28570251/comparative-clinical-study-of-the-wound-healing-effects-of-a-novel-micropore-particle-technology-effects-on-wounds-venous-leg-ulcers-and-diabetic-foot-ulcers
#9
Olga O Bilyayeva, Viacheslav V Neshta, Alexander A Golub, Frank Sams-Dood
OBJECTIVE: The purpose of this study was to determine the wound healing effects of Acapsil, a white, odorless powder based on micropore particle technology (MPPT) (Willingsford Ltd, Southampton, UK) by comparing it to Gentaxane (Gentaksan, Borshchagovsky CCP, Kyiv, Ukraine) (polydimethylsiloxane powder with gentamicin antibiotic) and Ioddicerin (Farmak, Kyiv, Ukraine) (iodine with dimethyl sulfoxide [DMSO]). MATERIALS AND METHODS: The study included 266 patients with primarily trophic ulcers caused by pancreatic diabetes and venous insufficiency of the lower extremities, carbuncles, phlegmons, infected third- or fourth-degree heat burns, and infiltrations of postoperative wounds...
May 25, 2017: Wounds: a Compendium of Clinical Research and Practice
https://www.readbyqxmd.com/read/28570131/simplifying-the-management-of-venous-leg-ulcers-choosing-appropriate-and-acceptable-compression-therapy
#10
Linda Nazarko
No abstract text is available yet for this article.
June 2, 2017: British Journal of Community Nursing
https://www.readbyqxmd.com/read/28567507/-a%C3%A2-standard-data-set-for-the-evaluation-of-venous-leg-ulcers-in-selective-contracts-national-consensus
#11
K Heyer, S Milde, J Schmitt, M May, J Helfrich, M Augustin
BACKGROUND: Selective agreements are becoming increasingly important in health care management. To date, no standard recommendations for the evaluation of selective contracts are available. OBJECTIVES: Against this background, a recommendation on the evaluation of selective contracts in patients with leg ulcers (LU) was developed and approved by the nationwide consensus conference. MATERIALS AND METHODS: Based on a systematic literature review and followed by a manual search through other possible evaluation indicators in the care of patients with LU, a Delphi-based consensus process was performed by various scientific societies, professional associations, insurances and supply networks...
May 31, 2017: Der Hautarzt; Zeitschrift Für Dermatologie, Venerologie, und Verwandte Gebiete
https://www.readbyqxmd.com/read/28549402/indications-for-medical-compression-stockings-in-venous-and-lymphatic-disorders-an-evidence-based-consensus-statement
#12
Eberhard Rabe, Hugo Partsch, Juerg Hafner, Christopher Lattimer, Giovanni Mosti, Martino Neumann, Tomasz Urbanek, Monika Huebner, Sylvain Gaillard, Patrick Carpentier
Objective Medical compression stockings are a standard, non-invasive treatment option for all venous and lymphatic diseases. The aim of this consensus document is to provide up-to-date recommendations and evidence grading on the indications for treatment, based on evidence accumulated during the past decade, under the auspices of the International Compression Club. Methods A systematic literature review was conducted and, using PRISMA guidelines, 51 relevant publications were selected for an evidence-based analysis of an initial 2407 unrefined results...
January 1, 2017: Phlebology
https://www.readbyqxmd.com/read/28529414/comparison-of-efficacy-of-autologous-platelet-rich-fibrin-versus-saline-dressing-in-chronic-venous-leg-ulcers-a-randomised-controlled-trial
#13
Anirudh Somani, Reena Rai
BACKGROUND: Venous leg ulcer is a chronic condition, and various treatment modalities are available. Platelet-rich fibrin (PRF) is one of the newer modalities and it contains fibroblast growth factor (GF), vascular endothelial GF, angiopoitin and platelet-derived GF which enhances the wound healing. Hence, we conducted a randomised controlled trial to compare the efficacy of PRF versus saline dressing in chronic venous leg ulcers. AIM: This study aims to compare the efficacy of autologous PRF with saline dressing in patients with chronic venous leg ulcer and to compare the mean reduction in ulcer area at the end of 4 weeks...
January 2017: Journal of Cutaneous and Aesthetic Surgery
https://www.readbyqxmd.com/read/28507589/successful-treatment-of-a-20-year-nonhealing-venous-leg-ulcer-in-a-patient-with-systemic-lupus-erythematosus
#14
Cenk Eray Yildiz, Cenk Conkbayir, Halil Erkam Tolgay, Kadir Ceviker, Mustafa Canikoglu, Omer Ali Sayin, Murat Ugurlucan
No abstract text is available yet for this article.
April 1, 2017: Archives of Medical Science: AMS
https://www.readbyqxmd.com/read/28504325/therapeutic-ultrasound-for-venous-leg-ulcers
#15
REVIEW
Nicky Cullum, Zhenmi Liu
BACKGROUND: Venous leg ulcers are a type of chronic, recurring, complex wound that is more common in people aged over 65 years. Venous ulcers pose a significant burden to patients and healthcare systems. While compression therapy (such as bandages or stockings) is an effective first-line treatment, ultrasound may have a role to play in healing venous ulcers. OBJECTIVES: To determine whether venous leg ulcers treated with ultrasound heal more quickly than those not treated with ultrasound...
May 15, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/28503700/venous-ultrasonography-findings-and-clinical-correlations-in-104-thai-patients-with-chronic-venous-insufficiency-of-the-legs
#16
Burapa Kanchanabat, Waigoon Stapanavatr
INTRODUCTION: The pattern of venous reflux in Thai patients with chronic venous insufficiency (CVI) was studied in correlation with clinical manifestations. METHODS: Ultrasonography findings and clinical data were prospectively collected and retrospectively reviewed. RESULTS: CVI was found in 104 legs of 79 patients (mean age 59.8 ± 12.5 years; C4: 24.1%, C5: 8.9%; C6: 67.1%). Among 104 legs, 6.7% had history of deep vein thrombosis (DVT)...
May 15, 2017: Singapore Medical Journal
https://www.readbyqxmd.com/read/28501660/alcohol-consumption-high-density-lipoprotein-cholesterol-antithrombin-iii-and-body-mass-index-are-associated-with-great-saphenous-vein-reflux-in-the-thigh
#17
Hyeonseung Kim, Hyangkyoung Kim, Je Hoon Park, Yong Han Kim, Sung Jin Oh, Byoung Jo Suh, Jong Kwon Park
BACKGROUND: Venous valvular reflux is the main cause of chronic venous dysfunction. However, the etiology of valvular reflux is not completely understood. We conducted this study to investigate new risk factors for venous reflux of the great saphenous vein (GSV) in the thigh. METHODS: We studied 139 consecutive patients (278 legs) who underwent Doppler ultrasonography at our hospital between March 2015 and February 2016 for leg discomfort with visible varicosities, edema, skin changes, or venous ulcer in the legs...
May 10, 2017: Annals of Vascular Surgery
https://www.readbyqxmd.com/read/28485879/evidence-for-silver-in-wound-care-meta-analysis-of-clinical-studies-from-2000-2015
#18
Joachim Dissemond, Johannes Georg Böttrich, Horst Braunwarth, Jörg Hilt, Patricia Wilken, Karl-Christian Münter
BACKGROUND: Given that the scientific evidence for silver in wound care is generally considered insufficient, there is uncertainty among users regarding its clinical use. MATERIAL AND METHODS: A group of experts evaluated the clinical studies on silver in wound management published from 2000-2015. RESULTS: Overall, 851 articles were identified, 173 of which were included and categorized. There were 31 randomized controlled trials (RCTs) and eight cohort studies...
May 2017: Journal der Deutschen Dermatologischen Gesellschaft, Journal of the German Society of Dermatology: JDDG
https://www.readbyqxmd.com/read/28485865/chronic-venous-insufficiency-a-review-of-pathophysiology-diagnosis-and-treatment
#19
Bettina Santler, Tobias Goerge
Chronic venous disease is a common disorder associated with a variety of symptoms in later disease stages but also with complications such as venous leg ulcer. This, in turn, has substantial socioeconomic effects and significantly impacts patients' quality of life. While there are a number of diagnostic procedures available, color-flow duplex ultrasound has become the gold standard. As regards therapeutic options, major advances have been made in recent decades. Today, there are alternatives to saphenofemoral ligation and stripping of the great saphenous vein, including endovenous thermal ablation techniques...
May 2017: Journal der Deutschen Dermatologischen Gesellschaft, Journal of the German Society of Dermatology: JDDG
https://www.readbyqxmd.com/read/28475441/clinical-outcomes-and-cost-effectiveness-of-three-different-compression-systems-in-newly-diagnosed-venous-leg-ulcers-in-the-uk
#20
J F Guest, G W Fuller, P Vowden
OBJECTIVE: To assess clinical outcomes and cost-effectiveness of using a two-layer cohesive compression bandage (TLCCB; Coban 2) compared with a two-layer compression system (TLCS; KTwo) and a four-layer compression system (FLCS; Profore) in treating newly-diagnosed venous leg ulcers (VLUs) in clinical practice in the UK, from the perspective of the NHS. METHOD: This was a retrospective cohort analysis of the case records of patients with newly-diagnosed VLUs randomly extracted from The Health Improvement Network (THIN) database (a nationally representative database of clinical practice among patients registered with general practitioners in the UK) who were treated with either TLCCB (n=200), TLCS (n=200) or FLCS (n=200)...
May 2, 2017: Journal of Wound Care
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