keyword
https://read.qxmd.com/read/38442908/cxcr4-whim-syndrome-is-a-cancer-predisposition-condition-for-virus-induced-malignancies
#21
JOURNAL ARTICLE
Clémentine Moulin, Blandine Beaupain, Felipe Suarez, Yves Bertrand, Sarah Cohen Beaussant, Alain Fischer, Julie Durin, Dana Ranta, Marion Espéli, Françoise Bachelerie, Christine Bellanné-Chantelot, Thierry Molina, Jean François Emile, Karl Balabanian, Claire Deback, Jean Donadieu
Warts, hypogammaglobulinaemia, infections and myelokathexis syndrome (WHIMS) is a rare combined primary immunodeficiency caused by the gain of function of the CXCR4 chemokine receptor. We present the prevalence of cancer in WHIMS patients based on data from the French Severe Chronic Neutropenia Registry and an exhaustive literature review. The median follow-up of the 14 WHIMS 'patients was 28.5 years. A central review and viral evaluation of pathological samples were organized, and we conducted a thorough literature review to identify all reports of WHIMS cases...
March 5, 2024: British Journal of Haematology
https://read.qxmd.com/read/38429823/prevalence-and-genotype-distribution-of-hpv-infections-among-women-in-chengdu-china
#22
JOURNAL ARTICLE
Junying Zhang, Tianzhi Zha, Xuemei Wang, Weijun He
BACKGROUND: Human papilloma virus (HPV) infection among female is the cause of cervical cancer and genital warts. In China, the HPV vaccination rate and the target population screening rate among females are low, and the aims of this study on the genotype distribution and prevalence of HPV infection were to provide more targeted strategies for the prevention and treatment of cervical cancer and HPV-related diseases. METHODS: Polymerase chain reaction-reverse dot blot (PCR-RDB) was adopted for HPV genotyping test, the prevalence and 23 genotypes distribution of HPV infections among 181,705 women in Chengdu from 2013 to 2020 were analysed...
March 1, 2024: Virology Journal
https://read.qxmd.com/read/38429784/prevalence-of-high-risk-human-papillomavirus-infection-and-cervical-lesions-among-female-migrant-head-porters-kayayei-in-accra-ghana-a-pilot-cross-sectional-study
#23
JOURNAL ARTICLE
Ethel Tekpor, Kofi Effah, Jerry Sifa, Joseph Emmanuel Amuah, Nana Owusu Mensah Essel, Seyram Kemawor, Comfort Mawusi Wormenor, Edna Sesenu, Stephen Danyo, Patrick Kafui Akakpo
BACKGROUND: Little attention has been given to the risk of high-risk human papillomavirus (hr-HPV) infection and cervical precancerous lesions among female migrant head porters (kayayei) in Ghana, as a vulnerable group, and to promote cervical screening in these women. This pilot study aimed to determine the prevalence of hr-HPV infection and cervical lesions among kayayei in Accra, the capital of the Greater Accra Region of Ghana and to describe our approach to triaging and treating these women...
March 1, 2024: BMC Public Health
https://read.qxmd.com/read/38417025/cost-effectiveness-of-nonavalent-hpv-vaccination-in-the-netherlands
#24
JOURNAL ARTICLE
Cody Palmer, Christiaan Dolk, Ugne Sabale, Wei Wang, Kunal Saxena
BACKGROUND: A bivalent human papillomavirus vaccine (2vHPV) is currently used in the Netherlands; a nonavalent vaccine (9vHPV) is also licensed. RESEARCH DESIGN AND METHODS: We compared the public health and economic benefits of 2vHPV- and 9vHPV-based vaccination strategies in the Netherlands over 100 years using a validated deterministic dynamic transmission metapopulation model. RESULTS: Compared to 2vHPV, the 9vHPV strategy averted an additional 3,245 cases of and 825 deaths from 9vHPV-strain-attributable cancers, 4,247 cases of and 190 deaths from recurrent respiratory papillomatosis (RRP), and 1,009,637 cases of anogenital warts (AGWs), with an incremental cost-effectiveness ratio (ICER) of €4,975 per quality-adjusted life year (QALY) gained...
February 28, 2024: Expert Review of Vaccines
https://read.qxmd.com/read/38390613/males-access-to-human-papillomavirus-vaccination-in-resource-limited-settings
#25
JOURNAL ARTICLE
Wubishet Gezimu, Firomsa Bekele, Teshome Bekana, Ababo Demeke
The human papillomavirus is known to cause cervical and anogenital cancer and benign anogenital and cutaneous warts. Both males and females can contract the virus during sexual intercourse and skin-to-skin contact. Communities in low- and middle-income countries, including Africa, are particularly suffering from human papillomavirus-related diseases, mainly cervical cancer. Vaccination is the most economical and efficient prevention strategy to control human papillomavirus-related diseases. Undoubtedly, to control all types of human papillomavirus-related morbidity and mortality, the entire at-risk, sexually active population needs to be vaccinated regardless of their sex...
2024: ImmunoTargets and Therapy
https://read.qxmd.com/read/38373470/successful-treatment-of-refractory-oral-condyloma-acuminatum-through-laser-photodynamic-therapy-combination
#26
Yimin He, Wending Gao, Feng Cai, Yingying Zhu, Rongjie Zuo, Huan Liu, Ying Gao
Condyloma acuminatum (CA) is a sexually transmitted disease primarily caused by human papilloma virus (HPV) infection, predominantly affecting the genital and anal regions. However, the occurrence of oral condyloma acuminatum (OCA) is relatively infrequent, although its incidence has been gradually rising in recent years. OCA presents unique challenges in terms of treatment efficacy and recurrence prevention due to its concealed location and distinctive anatomical characteristics. In this manuscript, we present a case study involving the use of laser combined with photodynamic therapy (PDT) for managing hard palate OCA...
February 17, 2024: Photodiagnosis and Photodynamic Therapy
https://read.qxmd.com/read/38369391/the-intentions-of-french-health-university-students-to-recommend-and-to-receive-the-hpv-vaccine-are-mainly-influenced-by-vaccine-knowledge-confidence-in-vaccines-and-personal-hpv-vaccination
#27
JOURNAL ARTICLE
Sébastien Bruel, Zohasina Rakotomampionona, Maxime Gignon, Nelly Agrinier, Ndeye Coumba Ndiaye, Christine Lasset, Bruno Giraudeau, Morgane Michel, Judith E Mueller, Aurélie Gauchet, Anne-Sophie Banaszuk, Nathalie Thilly, Amandine Gagneux-Brunon
INTRODUCTION: Despite documented effectiveness in preventing several cancers, genital warts and safety of Human Papillomavirus (HPV) vaccine, immunization coverage among French adolescents remains far from the 80 % target. University health students (HS) in France may promote HPV vaccine through a national service (Service Sanitaire des Etudiants en Santé). We aimed to evaluate intentions to recommend the HPV vaccine to friends and relatives, to receive HPV vaccine, and to identify factors associated with these attitudes...
February 17, 2024: Vaccine
https://read.qxmd.com/read/38358336/human-papillomavirus-vaccination-coverage-in-children-ages-9-17-years-united-states-2022
#28
JOURNAL ARTICLE
Maria A Villarroel, Adena M Galinsky, Peng-Jun Lu, Cassandra Pingali
Human papillomavirus (HPV) is the most common sexually transmitted infection in men and women in the United States (1). Vaccination prevents and controls HPV infection and associated outcomes, including genital warts, precancerous lesions, and certain cancers, such as cervical, vaginal, vulvar, anal, penile, and oropharyngeal (2,3). HPV vaccination in the United States has been recommended for girls since 2006 and for boys since 2011 and requires multiple doses (2,3). This vaccine, targeted for children ages 11-12 years, may be started at age 9...
February 2024: NCHS Data Brief
https://read.qxmd.com/read/38353174/knowledge-and-beliefs-of-greek-parents-towards-hpv-infection-and-vaccination%C3%A2-are-they-willing-to-vaccinate-their-sons
#29
JOURNAL ARTICLE
Aikaterini Toska, Dimitra Latsou, Chrysoula Paraskeuopoulou, Evangelos Fradelos, Eleni Albani, Charalambos Millionis, Mary Geitona, Dimitrios Papagiannis, Maria Saridi
OBJECTIVES: Human papillomavirus (HPV) stands as one of the prevalent sexually transmitted infections (STIs) and serves as the primary factor behind nearly all instances of cervical cancer, along with various other non-cancerous conditions like genital warts. Our objective was to explore the knowledge and beliefs of Greek parents regarding HPV infection and the vaccination of boys against HPV. METHODS: A cross-sectional study took place at a university hospital located in the Peloponnese region of Greece, from January to June 2021...
February 2, 2024: International Journal of Adolescent Medicine and Health
https://read.qxmd.com/read/38347247/comparison-of-nylon-flocked-swabs-and-cotton-swabs-in-the-detection-of-human-papillomavirus-infection-in-men
#30
JOURNAL ARTICLE
Mehmet Sarier, Esin Kasap, Mestan Emek, Elcin Konuk, Zerrin Barut, Kamil Dogru, Nevgun Sepin, Meltem Demir
BACKGROUND: Human papillomavirus (HPV) is an oncogenic virus and the commonest sexually transmitted pathogen worldwide. Appropriate sampling is an important factor in infection management. This study aimed to compare the efficacy of cotton swabs (CS) and nylon-flocked swabs (NFS) in sampling for HPV-DNA PCR testing in male patients with genital warts. METHODS: The study included men with genital warts who presented to the urology outpatient clinic of Antalya Medical Park Hospital...
February 12, 2024: International Urology and Nephrology
https://read.qxmd.com/read/38340885/effect-of-topical-5-aminolevulinic-acid-mediated-photodynamic-therapy-combined-with-co-2-laser-pretreatment-for-vaginal-condyloma-acuminate
#31
JOURNAL ARTICLE
Shan Jiang, Xia Hu, Xiaoyan Peng, Tiechi Lei
BACKGROUND: Condyloma acuminatum (CA) of the vagina is a sexually transmitted disease due to infection by human papilloma virus (HPV). The treatment efficacy of the conventional methods for vaginal CA is often unsatisfactory with a high recurrence rate. Topical 5-aminolevulinic acid-mediated photodynamic therapy (ALA-PDT) combined with CO2 laser pretreatment is a feasible approach for vaginal CA, but the effectiveness and safety need further evaluation. METHODS: This study enrolled 15 patients with vaginal CA...
February 8, 2024: Photodiagnosis and Photodynamic Therapy
https://read.qxmd.com/read/38333448/first-trimester-pregnancy-loss-due-to-condyloma-acuminata-a-twisted-tale-of-gravidity
#32
Saloni, Jyotsna Potdar, Apoorva Dave, Swati M Dahiphale
The human papillomavirus can induce condyloma acuminata, a benign papillomatous squamous growth with a fibrovascular core that arises in the vaginal canal. These illnesses typically afflict women who are fertile and are frequently encountered during pregnancy, manifesting with a variety of symptoms. The influences of hormones and vaginal secretions cause the lesion to expand quickly during pregnancy. Viral infections are known to be one risk factor for threatening abortions. Infection with human papillomavirus (HPV) during pregnancy has been associated with a risk for spontaneous abortion, preterm delivery, and abnormalities in the placenta...
January 2024: Curēus
https://read.qxmd.com/read/38318858/detection-and-genotyping-of-high-risk-human-papillomavirus-among-male-patients-during-2015-2023-in-beijing-china
#33
JOURNAL ARTICLE
Shuai Wang, Qin-Yi Ma, Juan Du, Ting-Ting Wei, Wan-Xue Zhang, Peng Wang, Yiguo Zhou, Ming Wei, Li Gu, Fuqiang Cui, Qing-Bin Lu
Few researches focused on human papillomavirus (HPV) in male patients. This study aimed to explore the detection rate and genotyping of HPV among male patients in Beijing to provide a reference for formulating prevention strategies for HPV infection. The cross-sectional study was conducted in Beijing Chaoyang Hospital from November 2015 to March 2023. It covered male patients from urology and dermatology departments. Fifteen high-risk HPV genotypes were detected by the multiplex real-time polymerase chain reaction method...
February 6, 2024: Emerging Microbes & Infections
https://read.qxmd.com/read/38315747/impact-of-different-cofactors-on-naturally-acquired-human-papillomavirus-antibody-levels-among-unvaccinated-pregnant-women
#34
JOURNAL ARTICLE
Laura Kirjavainen, Helmi Suominen, Kari Syrjänen, Tim Waterboer, Seija Grenman, Stina Syrjänen, Karolina Louvanto
Human papillomavirus (HPV) infections are common, transmitted by sexual and nonsexual routes. The present case-control setting was designed to examine potential cofactors associated with either persistently low or high HPV-antibody levels. The study subjects were from the Finnish HPV Family cohort of 329 baseline pregnant, non-HPV-vaccinated women, who were sampled for genital and oral HPV-DNA and HPV serology at baseline, and at 12, 24, and 36 months. Antibodies to the L1 major capsid protein of HPV 6, 11, 16, 18, and 45 were analyzed by multiplex HPV serology and HPV genotyping was performed...
February 5, 2024: Viral Immunology
https://read.qxmd.com/read/38297406/international-anal-neoplasia-society-s-consensus-guidelines-for-anal-cancer-screening
#35
JOURNAL ARTICLE
Elizabeth A Stier, Megan A Clarke, Ashish A Deshmukh, Nicolas Wentzensen, Yuxin Liu, I Mary Poynten, Eugenio Nelson Cavallari, Valeria Fink, Luis F Barroso, Gary M Clifford, Tamzin Cuming, Stephen E Goldstone, Richard J Hillman, Isabela Rosa-Cunha, Luciana La Rosa, Joel M Palefsky, Rosalyn Plotzker, Jennifer M Roberts, Naomi Jay
The International Anal Neoplasia Society (IANS) developed consensus guidelines to inform anal cancer screening use among various high-risk groups. Anal cancer incidence estimates by age among risk groups provided the basis to identify risk thresholds to recommend screening. Guided by risk thresholds, screening initiation at age 35 years was recommended for men who have sex with men (MSM) and transgender women (TW) with HIV. For other people with HIV and MSM and TW not with HIV, screening initiation at age 45 years was recommended...
January 31, 2024: International Journal of Cancer. Journal International du Cancer
https://read.qxmd.com/read/38293752/strengthening-the-relationship-between-intractable-plantar-keratosis-and-human-papillomavirus
#36
JOURNAL ARTICLE
Luis Alou, Ricardo Becerro-de-Bengoa-Vallejo, Marta E Losa-Iglesias, Juan Moreno, Rubén Sánchez-Gómez, Natalia González, David Sevillano
The aim of the study was to determine the presence of human papillomavirus (HPV) in patients with intractable plantar keratosis (IPK) by comparing the histopathological findings of biopsies. A prospective, observational, and concordance study was carried out. Three different specimens were taken from each IPK. A first punch was sent for histopathological examination, and a second punch and a superficial skin scraping were both sent for HPV  polymerase chain reaction (PCR) and type determination...
February 2024: Journal of Medical Virology
https://read.qxmd.com/read/38283478/acceptance-knowledge-and-attitude-of-parents-toward-the-human-papillomavirus-vaccine-in-the-eastern-region-of-saudi-arabia-a-cross-sectional-study
#37
JOURNAL ARTICLE
Latteefah Alnaeem, Shatha Alanizi, Ghaida AlQarni, Jana Alwadani, Fatimah Bomouzah, Zainab Ali
Background Human papillomavirus (HPV) is a common sexually transmitted virus associated with conditions such as skin warts and cervical cancer. Although many individuals clear the infection, some face persistent risks. Cervical cancer, which is linked to certain types of HPV, is a major health concern both globally and in Saudi Arabia, with preventive measures including HPV vaccination. However, parental knowledge and attitudes toward vaccinating their children vary. Therefore, this research aims to assess parental acceptance and understanding of the HPV vaccine in the Eastern Region of Saudi Arabia...
December 2023: Curēus
https://read.qxmd.com/read/38279540/application-of-cantharidin-retinoic-acid-cream-and-salicylic-acidy-in-multiple-palmoplantar-warts
#38
JOURNAL ARTICLE
Liyin Zhang, Shasha Cheng, Cheng Chen, Ling Fang, Chengjun Cui
OBJECTIVE: Multiple palmoplantar warts, caused by human papillomavirus (HPV) infection, were investigated for clinical efficacy using cantharidin, retinoic acid cream, and salicylic acid cream. METHODS: A total of 110 patients with multiple palmoplantar warts were enrolled. The experimental group (54 cases) received a 1:1:1 combination (CRS) of 0.25% cantharidin, 0.1% retinoic acid cream, and 5% salicylic acid, applied with pressurized encapsulation for 8 h every night, three times per week...
February 2024: Skin Research and Technology
https://read.qxmd.com/read/38267946/building-gender-specific-sexually-transmitted-infection-risk-prediction-models-using-catboost-algorithm-and-nhanes-data
#39
JOURNAL ARTICLE
Mengjie Hu, Han Peng, Xuan Zhang, Lefeng Wang, Jingjing Ren
BACKGROUND AND AIMS: Sexually transmitted infections (STIs) are a significant global public health challenge due to their high incidence rate and potential for severe consequences when early intervention is neglected. Research shows an upward trend in absolute cases and DALY numbers of STIs, with syphilis, chlamydia, trichomoniasis, and genital herpes exhibiting an increasing trend in age-standardized rate (ASR) from 2010 to 2019. Machine learning (ML) presents significant advantages in disease prediction, with several studies exploring its potential for STI prediction...
January 24, 2024: BMC Medical Informatics and Decision Making
https://read.qxmd.com/read/38250829/acceptance-of-the-human-papillomavirus-vaccine-among-general-men-and-men-with-a-same-sex-orientation-and-its-influencing-factors-a-systematic-review-and-meta-analysis
#40
REVIEW
Fang Shen, Yuxia Du, Kexin Cao, Can Chen, Mengya Yang, Rui Yan, Shigui Yang
The human papillomavirus (HPV) vaccine reduces the prevalence of genital warts and the cancers they are associated with in males. However, the vaccination of males has always been neglected. Here, we performed a meta-analysis to comprehend the acceptability of the HPV vaccine in men and the factors impacting vaccination intentions. We searched PubMed, Web of Science, Embase, Ovid, CNKI, and Wan Fang up to 5 July 2023 for studies that reported HPV vaccine acceptance among men. A random effects model was used to obtain the pooled acceptance rate, and subgroup analysis was performed...
December 22, 2023: Vaccines
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