Genetic anomoly

BACKGROUND/PURPOSE: This report describes the results of a group study of the Japanese Study Group of Anorectal Anomolies (JSGA) to determine the relative incidence of specific types of anorectal anomaly in Japan, and includes discussion of rectourethral fistula regarding the relationship between the levels of the fistula and blind end of the rectum, low type deformity, rare types, and associated anomalies. METHODS: A total of 1,992 patients (1,183 boys and 809 girls) registered from 1976 to 1995 were analyzed...

Evidence is presented that during development there is active regulation of the information content of the genome of Drosophila melanogaster. This regulation involves a large fraction of the DNA sequences active in transcription. RNA/DNA hybrids formed under the conditions described were primarily with middle repetitive DNA sequences. RNA molecules transcribed from the highly repetitive centromeric DNA sequences or from the attached less repetitive "spacer' DNA (Kram et al., 1972) are not present in larval RNA...