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https://www.readbyqxmd.com/read/29346651/bipartite-network-analysis-of-gene-sharings-in-the-microbial-world
#1
Eduardo Corel, Raphaël Méheust, Andrew K Watson, James O McInerney, Philippe Lopez, Eric Bapteste
Extensive microbial gene flows affect how we understand virology, microbiology, medical sciences, genetic modification and evolutionary biology. Phylogenies only provide a narrow view of these gene flows: plasmids and viruses, lacking core genes, cannot be attached to cellular life on phylogenetic trees. Yet viruses and plasmids have a major impact on cellular evolution, affecting both the gene content and the dynamics of microbial communities. Using bipartite graphs that connect up to 149,000 clusters of homologous genes with 8217 related and unrelated genomes, we can in particular show patterns of gene sharing that do not map neatly with the organismal phylogeny...
January 15, 2018: Molecular Biology and Evolution
https://www.readbyqxmd.com/read/29346480/changing-collective-social-norms-in-favour-of-reduced-harmful-use-of-alcohol-a-review-of-reviews
#2
Peter Anderson, Eva Jané-Llopis, Omer Syed Muhammad Hasan, Jürgen Rehm
Background: Public sector bodies have called for policies and programmes to shift collective social norms in disfavour of the harmful use of alcohol. This article aims to identify and summarize the evidence and propose how policies and programmes to shift social norms could be implemented and evaluated. Design: Review of reviews for all years to July 2017. Data sources: Searches on OVID Medline, Healthstar, Embase, PsycINFO, AMED, Social Work Abstracts, CAB Abstracts, Mental Measurements Yearbook, Joanna Briggs Institute EBP, Health and Psychosocial Instruments, International Pharmaceutical Abstracts, International Political Science Abstracts, NASW Clinical Register and Epub Ahead of Print databases...
January 16, 2018: Alcohol and Alcoholism: International Journal of the Medical Council on Alcoholism
https://www.readbyqxmd.com/read/29346376/evaluating-the-sustainability-scalability-and-replicability-of-an-sth-transmission-interruption-intervention-the-deworm3-implementation-science-protocol
#3
Arianna Rubin Means, Sitara S R Ajjampur, Robin Bailey, Katya Galactionova, Marie-Claire Gwayi-Chore, Katherine Halliday, Moudachirou Ibikounle, Sanjay Juvekar, Khumbo Kalua, Gagandeep Kang, Pallavi Lele, Adrian J F Luty, Rachel Pullan, Rajiv Sarkar, Fabian Schär, Fabrizio Tediosi, Bryan J Weiner, Elodie Yard, Judd Walson
Hybrid trials that include both clinical and implementation science outcomes are increasingly relevant for public health researchers that aim to rapidly translate study findings into evidence-based practice. The DeWorm3 Project is a series of hybrid trials testing the feasibility of interrupting the transmission of soil transmitted helminths (STH), while conducting implementation science research that contextualizes clinical research findings and provides guidance on opportunities to optimize delivery of STH interventions...
January 2018: PLoS Neglected Tropical Diseases
https://www.readbyqxmd.com/read/29346099/cell-membrane-tracking-in-living-brain-tissue-using-differential-interference-contrast-microscopy
#4
John Lee, Ilya Kolb, Craig R Forest, Christopher J Rozell
Differential interference contrast (DIC) microscopy is widely used for observing unstained biological samples that are otherwise optically transparent. Combining this optical technique with machine vision could enable the automation of many life science experiments; however, identifying relevant features under DIC is challenging. In particular, precise tracking of cell boundaries in a thick ( ) slice of tissue has not previously been accomplished. We present a novel deconvolution algorithm that achieves the state-of-the-art performance at identifying and tracking these membrane locations...
April 2018: IEEE Transactions on Image Processing: a Publication of the IEEE Signal Processing Society
https://www.readbyqxmd.com/read/29345487/on-the-general-acceptance-of-confessions-research-opinions-of-the-scientific-community
#5
Saul M Kassin, Allison D Redlich, Fabiana Alceste, Timothy J Luke
Eighty-seven experts on the psychology of confessions-many of whom were highly published, many with courtroom experience-were surveyed online about their opinions on 30 propositions of relevance to deception detection, police interrogations, confessions, and relevant general principles of psychology. As indicated by an agreement rate of at least 80%, there was a strong consensus that several findings are sufficiently reliable to present in court. This list includes but is not limited to the proposition that the risk of false confessions is increased not only by explicit threats and promises but by 2 common interrogation tactics-namely, the false evidence ploy and minimization tactics that imply leniency by offering sympathy and moral justification...
January 2018: American Psychologist
https://www.readbyqxmd.com/read/29339936/satellite-stories-capturing-professional-experiences-of-academic-health-sciences-librarians-working-in-delocalized-health-sciences-programs
#6
Jackie Phinney, Amanda Rose Horsman
Objective: Health sciences training programs have progressively expanded onto satellite campuses, allowing students the opportunity to learn in communities away from an academic institution's main campus. This expansion has encouraged a new role for librarians to assume, in that a subset of health sciences librarians identify as "satellite librarians" who are permanently located at a distance from the main campus. Due to the unique nature of this role and lack of existing data on the topic, the authors investigated the experiences and perceptions of this unique group of information professionals...
January 2018: Journal of the Medical Library Association: JMLA
https://www.readbyqxmd.com/read/29330864/allergy-committed-to-progress-in-allergy-and-immunology
#7
Hans-Uwe Simon, Thomas Bieber
After more than 8 years, our terms as Co-Editors-in-Chief have now reached an end. We are thankful for having had the privilege to serve the community in this position. We think that we have reached our original goal of increasing the overall quality of the journal (1). The science which is reported every month in Allergy is of high quality and wide interest, largely contributing to the development of the fields of Allergy and Immunology. The impact of the journal is high, as reflected by its present impact factor of 7...
January 13, 2018: Allergy
https://www.readbyqxmd.com/read/29330132/an-overview-of-the-safety-pharmacology-society-strategic-plan
#8
M K Pugsley, S Authier, J E Koerner, W S Redfern, C G Markgraf, T Brabham, K Correll, M V Soloviev, A Botchway, M Engwall, M Traebert, J-P Valentin, T J Mow, A Greiter-Wilke, D J Leishman, H M Vargas
Safety Pharmacology studies are conducted to characterize the confidence by which biologically active new chemical entities (NCE) may be anticipated as safe. Non-clinical safety pharmacology studies aim to detect and characterize potentially undesirable pharmacodynamic activities using an array of in silico, in vitro and in vivo animal models. While a broad spectrum of methodological innovation and advancement of the science occurs within the Safety Pharmacology Society, the society also focuses on partnerships with health authorities and technology providers and facilitates interaction with organizations of common interest such as pharmacology, physiology, neuroscience, cardiology and toxicology...
January 9, 2018: Journal of Pharmacological and Toxicological Methods
https://www.readbyqxmd.com/read/29329784/regulatory-science-an-underappreciated-component-of-translational-research
#9
Rodney Rouse, Issam Zineh, David G Strauss
Translational science refers to translating basic scientific findings to practical application (i.e., 'bench-to-bedside'). An underappreciated aspect of translational science is regulatory science. Herein, we focus on the importance of regulatory science to facilitate development of innovative new drugs and optimize use of approved drugs, with a call for community participation.
January 9, 2018: Trends in Pharmacological Sciences
https://www.readbyqxmd.com/read/29329715/ten-questions-you-should-consider-before-submitting-an-article-to-a-scientific-journal
#10
A Falcó-Pegueroles, D Rodríguez-Martín
Investigating involves not only knowing the research methods and designs; it involves knowing the strategies for disseminating and publishing the results in scientific journals. An investigation is considered complete when it is published and is disclosed to the scientific community. The publication of a manuscript is not simple, since it involves examination by a rigorous editorial process evaluator to ensure the scientific quality of the proposal. The objective of this article is to communicate to potential authors the main errors or deficiencies that typically and routinely explain the decision by the referees of scientific journals not to accept a scientific article...
January 9, 2018: Enfermería Intensiva
https://www.readbyqxmd.com/read/29327992/digitalhub-a-repository-focused-on-the-future
#11
Violeta Ilik, Piotr Hebal, Anton Olson, Susan Wishnetsky, Joelen Pastva, Ramune Kubilius, Jonathan Shank, Karen Gutzman, Margarita Chung, Kristi Holmes
The DigitalHub scholarly repository was developed and launched at the Galter Health Sciences Library for the Feinberg School of Medicine and the greater Northwestern Medicine community. The repository was designed to allow scholars the ability to create, share, and preserve a range of citable digital outputs. This article traces the evolution of DigitalHub's development and engagement activities, highlighting project challenges, innovations, success stories, and the team-based approach that was employed to successfully achieve project goals...
January 2018: Medical Reference Services Quarterly
https://www.readbyqxmd.com/read/29327981/hiv-aids-outreach-curriculum-development-and-skills-training-to-health-and-information-professionals
#12
Gretchen M Kuntz, Nancy Schaefer, Hannah F Norton, Michele R Tennant
With funding from the National Library of Medicine HIV/AIDS Community Information Outreach Program (ACIOP), librarians at the University of Florida Health Sciences Libraries partnered with university and community groups to facilitate collaboration, develop new information resources, develop information-seeking skills, and raise general awareness surrounding HIV/AIDS risks, prevention, and treatment. This article describes the skills development elements of the project, including development and implementation of an HIV/AIDS information resource curriculum for health care providers, social services professionals, and public librarians within the project's partner organizations...
January 2018: Medical Reference Services Quarterly
https://www.readbyqxmd.com/read/29323832/influences-of-a-church-based-intervention-on-falls-risk-among-seniors
#13
Morgan Briggs, Jeffrey A Morzinski, Julie Ellis
BACKGROUND AND OBJECTIVES: Prior studies illustrate that community-based programs effectively decrease falls risk in older adults and that faith-based programs improve health behaviors. The literature is unclear whether faith-based initiatives reduce seniors' fall risks. To tackle this gap, a long-term partnership led by 10 urban churches, a nearby nursing school, and a medical school developed a study with 3 objectives: determine baseline health concerns associated with falls (eg, depression, polypharmacy), implement a nurse-led, faith-based health education initiative for community-dwelling African American seniors at-risk of hospitalization, and assess pre- to post -program fall frequency...
August 2017: WMJ: Official Publication of the State Medical Society of Wisconsin
https://www.readbyqxmd.com/read/29323122/effect-of-rhythmic-auditory-cueing-on-parkinsonian-gait-a-systematic-review-and-meta-analysis
#14
Shashank Ghai, Ishan Ghai, Gerd Schmitz, Alfred O Effenberg
The use of rhythmic auditory cueing to enhance gait performance in parkinsonian patients' is an emerging area of interest. Different theories and underlying neurophysiological mechanisms have been suggested for ascertaining the enhancement in motor performance. However, a consensus as to its effects based on characteristics of effective stimuli, and training dosage is still not reached. A systematic review and meta-analysis was carried out to analyze the effects of different auditory feedbacks on gait and postural performance in patients affected by Parkinson's disease...
January 11, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29322939/public-health-psychopharmacology-a-new-research-discipline-comes-of-age
#15
C Barbui, G Ostuzzi, B Godman
Research evidence guiding the identification of pragmatic and effective actions aimed at improving the selection, availability, affordability and rational prescribing of medicines for mental disorders is sparse and inconsistent. In order to boost the development of new research, in this commentary we suggest to organise and classify all the activities in this area under a common theoretical framework and nomenclature, adopting the term 'public health psychopharmacology'. Public health psychopharmacology is proposed as a research discipline, based on contributions from the fields of regulatory science, health services research and implementation science...
February 2018: Epidemiology and Psychiatric Sciences
https://www.readbyqxmd.com/read/29320494/sexually-transmitted-infections-in-the-era-of-antiretroviral-based-hiv-prevention-priorities-for-discovery-research-implementation-science-and-community-involvement
#16
Jeanne M Marrazzo, Julia C Dombrowski, Kenneth H Mayer
Jeanne M. Marrazzo and colleagues join PLOS Medicine's Collection on the prevention, diagnosis, and treatment of STIs with a Perspective on HIV research imperatives in our time of effective viral suppression and pre-exposure prophylaxis.
January 2018: PLoS Medicine
https://www.readbyqxmd.com/read/29318939/the-m%C3%A3-thode-de-nomenclature-chimique-1787-a-document-of-transition
#17
Wolfgang Lefèvre
The Méthode de nomenclature chimique, published by the Académie Royale des Sciences in 1787, is rightly praised as a landmark in the history of early modern chemistry. It is also - though less rightly - considered to be a fruit of Lavoisier's Chemical Revolution. In fact, main features of the Méthode's nomenclatural and classificatory proposal rest on fundamental chemical conceptions that were shared by adherents of the phlogistic chemical system as well. After a short presentation of the Méthode's four authors (Berthollet, Fourcroy, Guyton de Morveau, and Lavoisier) and the circumstances of their collaboration, my paper will focus on those features of the Méthode that illuminate decisive achievements of the entire community of eighteenth-century chemists, as well as those features that reveal an unsettled state of many of its convictions...
January 10, 2018: Ambix
https://www.readbyqxmd.com/read/29318437/replication-of-a-controlled-community-prevention-trial-results-from-a-local-implementation-of-science-based-intervention-to-reduce-impaired-driving
#18
Michael D George, Harold D Holder, Paul N McKenzie, Heather R Mueller, Donna C Herchek, Barry S Faile
We tested the generalizability of a science-based community prevention design to reduce DUI crashes. Previous researcher-led studies have confirmed the effects of an intervention design of visible enforcement coupled with heightened public awareness of enforcement to increase driver perception of likely detection for drinking and driving. A community coalition based the project on a prevention intervention model that included two key intermediate variables: levels of visible enforcement and of public awareness of enforcement...
January 9, 2018: Journal of Primary Prevention
https://www.readbyqxmd.com/read/29316201/women-s-situation-specific-strategies-in-managing-participation-restrictions-due-to-early-rheumatoid-arthritis-a-gender-comparison
#19
Gunnel Östlund, Mathilda Björk, Ingrid Thyberg, Eva Valtersson, Annette Sverker
INTRODUCTION: The present study explored how women describe their use of situation-specific strategies when managing rheumatoid arthritis (RA). The aim was also to compare women's strategies with those of men, and see the extent to which they used the same strategies. METHODS: The data were collected using semi-structured interviews based on the critical incident technique. The sample consisted of women with early rheumatic arthritis (n = 34), and the results were compared with data reported in a previous study on men (n = 25) from the same cohort...
January 9, 2018: Musculoskeletal Care
https://www.readbyqxmd.com/read/29314746/integrative-review-of-the-intersection-of-green-space-and-neighborhood-violence
#20
Gibran C Mancus, Jacquelyn Campbell
PURPOSE: To systematically analyze evidence about the impact of green space on the perception and actual safety of residents of urban neighborhoods. DESIGN AND ORGANIZING CONSTRUCT: Systematic review of green space and violence based on Broome review criteria. METHODS: One landmark study prompted the initial hand search and identification of search terms. Twenty-three quantitative, five qualitative, and two mixed-methods studies were found in the urban planning, public health, medical, and psychological literature that met the following criteria: analyzed green space and violence as factors in the perception of safety as an outcome measure, including action taken by being outside for recreation, exercise, or self-report in the survey...
January 4, 2018: Journal of Nursing Scholarship
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