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https://www.readbyqxmd.com/read/28332160/robust-motion-tracking-in-liver-from-2d-ultrasound-images-using-supporters
#1
Ece Ozkan, Christine Tanner, Matej Kastelic, Oliver Mattausch, Maxim Makhinya, Orcun Goksel
PURPOSE: Effectiveness of image-guided radiation therapy with precise dose delivery depends highly on accurate target localization, which may involve motion during treatment due to, e.g., breathing and drift. Therefore, it is important to track the motion and adjust the radiation delivery accordingly. Tracking generally requires reliable target appearance and image features, whereas in ultrasound imaging acoustic shadowing and other artifacts may degrade the visibility of a target, leading to substantial tracking errors...
March 22, 2017: International Journal of Computer Assisted Radiology and Surgery
https://www.readbyqxmd.com/read/28332099/integrated-multisystem-analysis-in-a-mental-health-and-criminal-justice-ecosystem
#2
Erin Falconer, Tal El-Hay, Dimitris Alevras, John P Docherty, Chen Yanover, Alan Kalton, Yaara Goldschmidt, Michal Rosen-Zvi
BACKGROUND: Patients with a serious mental illness often receive care that is fragmented due to reduced availability of or access to resources, and inadequate, discontinuous, and uncoordinated care across health, social services, and criminal justice organizations. This article describes the creation of a multisystem analysis that derives insights from an integrated dataset including patient access to case management services, medical services, and interactions with the criminal justice system...
December 2017: Health & Justice
https://www.readbyqxmd.com/read/28331891/differentiation-of-arterioles-from-venules-in-mouse-histology-images-using-machine-learning
#3
J Sachi Elkerton, Yiwen Xu, J Geoffrey Pickering, Aaron D Ward
Analysis and morphological comparison of the arteriolar and venular components of a microvascular network are essential to our understanding of multiple diseases affecting every organ system. We have developed and evaluated the first fully automatic software system for differentiation of arterioles from venules on high-resolution digital histology images of the mouse hind limb immunostained with smooth muscle [Formula: see text]-actin. Classifiers trained on statistical and morphological features by supervised machine learning provided useful classification accuracy for differentiation of arterioles from venules, achieving an area under the receiver operating characteristic curve of 0...
April 2017: Journal of Medical Imaging
https://www.readbyqxmd.com/read/28331859/a-copmarative-review-of-electronic-prescription-systems-lessons-learned-from-developed-countries
#4
REVIEW
Mahnaz Samadbeik, Maryam Ahmadi, Farahnaz Sadoughi, Ali Garavand
This review study aimed to compare the electronic prescription systems in five selected countries (Denmark, Finland, Sweden, England, and the United States). Compared developed countries were selected by the identified selection process from the countries that have electronic prescription systems. Required data were collected by searching the valid databases, most widely used search engines, and visiting websites related to the national electronic prescription system of each country and also sending E-mails to the related organizations using specifically designed data collection forms...
January 2017: Journal of Research in Pharmacy Practice
https://www.readbyqxmd.com/read/28331007/advantages-of-comparative-studies-in-songbirds-to-understand-the-neural-basis-of-sensorimotor-integration
#5
Karagh Murphy, Logan S James, Jon T Sakata, Jonathan F Prather
Sensorimotor integration is the process through which the nervous system creates a link between motor commands and associated sensory feedback. This process allows for the acquisition and refinement of many behaviors, including learned communication behaviors like speech and birdsong. Consequently, it is important to understand fundamental mechanisms of sensorimotor integration, and comparative analyses of this process can provide vital insight. Songbirds offer a powerful comparative model system to study how the nervous system links motor and sensory information for learning and control...
March 22, 2017: Journal of Neurophysiology
https://www.readbyqxmd.com/read/28330785/the-interplay-between-angiotensin-ii-tlr4-and-hypertension
#6
REVIEW
Vinicia Campana Biancardi, Gisele Facholi Bomfim, Wagner Luis Reis, Sarah Al-Gassimi, Kenia Pedrosa Nunes
Hypertension is a multifactorial disease. Although a number of different underlying mechanisms have been learned from the various experimental models of the disease, hypertension still poses challenges for treatment. Angiotensin II plays an unquestionable role in blood pressure regulation acting through central and peripheral mechanisms. During hypertension, dysregulation of the Renin-Angiotensin System is associated with increased expression of pro-inflammatory cytokines and reactive oxygen species causing kidney damage, endothelial dysfunction, and increase in sympathetic activity, among other damages, eventually leading to decline in organ function...
March 19, 2017: Pharmacological Research: the Official Journal of the Italian Pharmacological Society
https://www.readbyqxmd.com/read/28330348/learning-molecular-energies-using-localized-graph-kernels
#7
Grégoire Ferré, Terry Haut, Kipton Barros
Recent machine learning methods make it possible to model potential energy of atomic configurations with chemical-level accuracy (as calculated from ab initio calculations) and at speeds suitable for molecular dynamics simulation. Best performance is achieved when the known physical constraints are encoded in the machine learning models. For example, the atomic energy is invariant under global translations and rotations; it is also invariant to permutations of same-species atoms. Although simple to state, these symmetries are complicated to encode into machine learning algorithms...
March 21, 2017: Journal of Chemical Physics
https://www.readbyqxmd.com/read/28329840/a-multi-faceted-approach-to-promote-comprehension-of-online-health-information-among-older-adults
#8
Jessie Chin, Darcie D Moeller, Jessica Johnson, Elise A G Duwe, James F Graumlich, Michael D Murray, Daniel G Morrow
Purpose of the Study: Older adults' self-care often depends on understanding and utilizing health information. Inadequate health literacy among older adults poses a barrier to self-care because it hampers comprehension of this information, particularly when the information is not well-designed. Our goal was to improve comprehension of online health information among older adults with hypertension who varied in health literacy abilities. Design and Methods: We identified passages about hypertension self-care from credible websites (typical passages)...
March 10, 2017: Gerontologist
https://www.readbyqxmd.com/read/28328673/remote-damage-control-during-the-attacks-on-paris-lessons-learned-by-the-paris-fire-brigade-and-evolutions-in-the-rescue-system
#9
Xavier Lesaffre, Jean-Pierre Tourtier, Yann Violin, Benoit Frattini, Catherine Rivet, Olivier Stibbe, Florian Faure, Anne Godefroy, Jean-Claude Gallet, Sylvain Ausset
On November 13, 2015, in 40 minutes, Paris suffered 4 suicide bombers attacks, shootings at 3 different restaurant terraces and an attack on the Bataclan concert hall resulting in 130 dead and 495 wounded. How did the Parisian rescue system respond and how did it evolve since?We proved we could deploy quickly wide prehospital and hospital resources and teams' equipment and preparedness is being further developed. In order to secure a swifter initial response we need a better integration of the operators of the rescue chain with a simpler and more robust organization as well as improved communications channels...
March 20, 2017: Journal of Trauma and Acute Care Surgery
https://www.readbyqxmd.com/read/28328509/multitask-protein-function-prediction-through-task-dissimilarity
#10
Marco Frasca, Nicolo Cesa-Bianchi
Automated protein function prediction is a challenging problem with distinctive features, such as the hierarchical organization of protein functions and the scarcity of annotated proteins for most biological functions. We propose a multitask learning algorithm addressing both issues. Unlike standard multitask algorithms, which use task (protein functions) similarity information as a bias to speed up learning, we show that dissimilarity information enforces separation of rare class labels from frequent class labels, and for this reason is better suited for solving unbalanced protein function prediction problems...
March 17, 2017: IEEE/ACM Transactions on Computational Biology and Bioinformatics
https://www.readbyqxmd.com/read/28328209/multidk-a-multiple-descriptor-multiple-kernel-approach-for-molecular-discovery-and-its-application-to-the-discovery-of-organic-flow-battery-electrolytes
#11
Sung-Jin Kim, Adrián Jinich, Alán Aspuru-Guzik
We propose a multiple descriptor multiple kernel (MultiDK) method for efficient molecular discovery using machine learning. We show that the MultiDK method improves both the speed and accuracy of molecular property prediction. We apply the method to the discovery of electrolyte molecules for aqueous redox flow batteries. Using \emph{multiple-type - as opposed to single-type - descriptors}, we obtain more relevant features for machine learning. Following the principle of 'wisdom of the crowds', the combination of multiple-type descriptors significantly boosts prediction performance...
March 22, 2017: Journal of Chemical Information and Modeling
https://www.readbyqxmd.com/read/28328009/microenvironmental-factors-that-regulate-mesenchymal-stem-cells-lessons-learned-from-the-study-of-heterotopic-ossification
#12
REVIEW
Chen Kan, Lijun Chen, Yangyang Hu, Haimei Lu, Yuyun Li, John A Kessler, Lixin Kan
Bone marrow contains a non-hematopoietic, clonogenic, multipotent population of stromal cells that are later called mesenchymal stem cells (MSC). Similar cells that share many common features with MSC are also found in other organs, which are thought to contribute both to normal tissue regeneration and to pathological processes such as heterotopic ossification (HO), the formation of ectopic bone in soft tissue. Understanding the microenvironmental factors that regulate MSC in vivo is essential both for understanding the biology of the stem cells and for effective translational applications of MSC...
March 22, 2017: Histology and Histopathology
https://www.readbyqxmd.com/read/28327198/improving-the-adaptability-of-who-evidence-informed-guidelines-for-nutrition-actions-results-of-a-mixed-methods-evaluation
#13
Maria Cecilia Dedios, Alexo Esperato, Luz Maria De-Regil, Juan Pablo Peña-Rosas, Susan L Norris
BACKGROUND: Over the past decade, the World Health Organization (WHO) has implemented a standardized, evidence-informed guideline development process to assure technically sound and policy-relevant guidelines. This study is an independent evaluation of the adaptability of the guidelines produced by the Evidence and Programme Guidance unit, at the Department of Nutrition for Health and Development (NHD). The study systematizes the lessons learned by the NHD group at WHO. METHODS: We used a mixed methods approach to determine the adaptability of the nutrition guidelines...
March 21, 2017: Implementation Science: IS
https://www.readbyqxmd.com/read/28325448/diagnosis-of-autism-through-eeg-processed-by-advanced-computational-algorithms-a-pilot-study
#14
Enzo Grossi, Chiara Olivieri, Massimo Buscema
BACKGROUND: Multi-Scale Ranked Organizing Map coupled with Implicit Function as Squashing Time algorithm(MS-ROM/I-FAST) is a new, complex system based on Artificial Neural networks (ANNs) able to extract features of interest in computerized EEG through the analysis of few minutes of their EEG without any preliminary pre-processing. A proof of concept study previously published showed accuracy values ranging from 94%-98% in discerning subjects with Mild Cognitive Impairment and/or Alzheimer's Disease from healthy elderly people...
April 2017: Computer Methods and Programs in Biomedicine
https://www.readbyqxmd.com/read/28325203/developing-and-evaluating-an-automated-all-cause-harm-trigger-system
#15
Christine Sammer, Susanne Miller, Cason Jones, Antoinette Nelson, Paul Garrett, David Classen, David Stockwell
BACKGROUND: From 2009 through 2012, the Adventist Health System Patient Safety Organization (AHS PSO) used the Global Trigger Tool method for harm identification and demonstrated harm reduction. Although the awareness of harm demonstrated opportunities for improvement across the system, leaders determined that the human and fiscal resources required to continue with a retrospective manual harm identification process were unsustainable. In addition, there was growing concern that the identification of harm after the patient's discharge did not allow for intervention during the hospital stay...
April 2017: Joint Commission Journal on Quality and Patient Safety
https://www.readbyqxmd.com/read/28325084/application-of-a-contextual-instructional-framework-in-a-continuing-professional-development-training-program-for-physiotherapists-in-rwanda
#16
Kim Dunleavy, Julia Chevan, Antoinette P Sander, Jean Damascene Gasherebuka, Monika Mann
BACKGROUND: Continuing professional development is an important component of capacity building in low resource countries. The purpose of this case study is to describe the use of a contextual instructional framework to guide the processes and instructional design choices for a series of continuing professional development courses for physiotherapists in Rwanda. METHODS: Four phases of the project are described: (1) program proposal, needs assessment and planning, (2) organization of the program and instructional design, (3) instructional delivery and (4) evaluation...
March 22, 2017: Disability and Rehabilitation
https://www.readbyqxmd.com/read/28324169/roles-of-centromedian-parafascicular-nuclei-of-thalamus-and-cholinergic-interneurons-in-the-dorsal-striatum-in-associative-learning-of-environmental-events
#17
REVIEW
Ko Yamanaka, Yukiko Hori, Takafumi Minamimoto, Hiroshi Yamada, Naoyuki Matsumoto, Kazuki Enomoto, Toshihiko Aosaki, Ann M Graybiel, Minoru Kimura
The thalamus provides a massive input to the striatum, but despite accumulating evidence, the functions of this system remain unclear. It is known, however, that the centromedian (CM) and parafascicular (Pf) nuclei of the thalamus can strongly influence particular striatal neuron subtypes, notably including the cholinergic interneurons of the striatum (CINs), key regulators of striatal function. Here, we highlight the thalamostriatal system through the CM-Pf to striatal CINs. We consider how, by virtue of the direct synaptic connections of the CM and PF, their neural activity contributes to the activity of CINs and striatal projection neurons (SPNs)...
March 21, 2017: Journal of Neural Transmission
https://www.readbyqxmd.com/read/28321906/development-and-feasibility-of-a-community-partnered-nutrition-intervention-targeting-rural-migrant-communities-in-the-dominican-republic
#18
Genevieve Maliszewski, Maithe Enriquez, An-Lin Cheng, Pamela Logan, Jennifer Watts
OBJECTIVE: Research on health initiatives for rural batey communities in the Dominican Republic is needed. DESIGN AND SAMPLE: This study utilized a pretest-posttest design to examine the feasibility and acceptability of a nutritional intervention targeting rural migrant sugarcane families. Participants (N = 310) were primarily female (61%) and ranged in age from 13 to 64 years (M = 25.9; SD = 10.4). A convenience sample was recruited from six rural bateyes in the southern region of the Dominican Republic...
March 21, 2017: Public Health Nursing
https://www.readbyqxmd.com/read/28321459/-the-microbiome-and-autoimmunity
#19
T Schröder, S Ibrahim
An abundant and diverse set of commensal microbial communities covers the body's surfaces, collectively so-called microbiome. It has a functional impact on various immune processes and modulates many health-related processes, including autoimmunity. An active site of microorganism-host interplay is the intestinal mucosa. Growing evidence has helped us to learn how a specific microbiota composition and its functionality determine the intestinal barrier function and, furthermore, modulate pro-inflammatory and anti-inflammatory immune mechanisms in remote organs...
March 20, 2017: Der Internist
https://www.readbyqxmd.com/read/28321393/an-integrated-approach-to-falls-prevention-a-model-for-linking-clinical-and-community-interventions-through-the-massachusetts-prevention-and-wellness-trust-fund
#20
Laura J Coe, Julie Ann St John, Santhi Hariprasad, Kalpana N Shankar, Patricia A MacCulloch, Amy L Bettano, Jean Zotter
Older adult falls continue to be a public health priority across the United States-Massachusetts (MA) being no exception. The MA Prevention and Wellness Trust Fund (PWTF) program within the MA Department of Public Health aims to reduce the physical and economic burdens of chronic health conditions by linking evidence-based clinical care with community intervention programs. The PWTF partnerships that focused on older adult falls prevention integrated the Centers for Disease Control and Prevention's Stopping Elderly Accidents, Death and Injuries toolkit into clinical settings...
2017: Frontiers in Public Health
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