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https://www.readbyqxmd.com/read/29224257/models-of-care-for-non-invasive-ventilation-in-the-acute-copd-comparison-of-three-tertiary-hospitals-act3-study
#1
Kerry Parker, Vara Perikala, Ali Aminazad, Zheng Deng, Brigitte Borg, Catherine Buchan, Jo Toghill, Louis B Irving, Jeremy Goldin, David Charlesworth, Ajay Mahal, Suhith Illesinghe, Matthew T Naughton, Alan Young
BACKGROUND AND OBJECTIVE: Non-invasive ventilation (NIV) improves clinical outcomes in hypercapnic acute exacerbations of COPD (AECOPD), but the optimal model of care remains unknown. METHODS: We conducted a prospective observational non-inferiority study comparing three models of NIV care: general ward (Ward) (1:4 nurse to patient ratio, thrice weekly consultant ward round), a high dependency unit (HDU) (1:2 ratio, twice daily ward round) and an intensive care unit (ICU) (1:1 ratio, twice daily ward round) model in three similar teaching tertiary hospitals...
December 10, 2017: Respirology: Official Journal of the Asian Pacific Society of Respirology
https://www.readbyqxmd.com/read/29224226/bizarre-appearance-of-chronic-cutaneous-lupus-erythematosus-of-face-mimicking-factitial-dermatitis
#2
Ružica Jurakić Tončić, Branka Marinović, Anamaria Balić, Borna Pavičić, Suzana Ljubojević Hadžavdić, Mirna Bradamant
Old dermatological wisdom says that syphilis and lupus are great imitators. Cutaneous manifestations of lupus erythematosus (LE) are usually characteristic, however, some patients may present with a less typical clinical picture. Correct diagnosis of cutaneous lupus erythematosus (CLE) requires a high level of clinical suspicion and understanding of broad differential diagnosis. Early lesions of CLE are sometimes difficult to diagnose, both clinically and histopathologically. This article is protected by copyright...
December 10, 2017: Journal of the European Academy of Dermatology and Venereology: JEADV
https://www.readbyqxmd.com/read/29224085/aphasia-and-cognitive-impairment-decrease-the-reliability-of-rntms-language-mapping
#3
Vera Schwarzer, Ina Bährend, Tizian Rosenstock, Felix R Dreyer, Peter Vajkoczy, Thomas Picht
BACKGROUND: Navigated transcranial magnetic stimulation (nTMS) is a non-invasive mapping tool to locate functional areas of the brain. While gaining importance in the preoperative planning process in motor eloquent regions, its usefulness for reliably identifying language areas is still being discussed. The aim of this study was to identify biometric factors which might influence and therefore bias the results of repetitive nTMS (rnTMS) over cortex areas relevant for language. METHOD: We included data of 101 patients with language eloquent brain lesions who underwent preoperative rnTMS examination bihemispherically...
December 9, 2017: Acta Neurochirurgica
https://www.readbyqxmd.com/read/29224056/a-5-year-multicenter-prospective-cohort-study-on-the-long-term-visual-prognosis-and-predictive-factors-for-visual-outcome-in-japanese-patients-with-age-related-macular-degeneration-the-amd2000-study
#4
Yumiko Akagi-Kurashige, Akitaka Tsujikawa, Mitsuko Yuzawa, Tatsuro Ishibashi, Hideo Nakanishi, Eiji Nakatani, Satoshi Teramukai, Masanori Fukushima, Nagahisa Yoshimura
PURPOSE: In this study (AMD2000), we aimed to determine the visual prognosis of Japanese patients with age-related macular degeneration (AMD). METHODS: This was a multicenter prospective observational cohort study. In total, 460 patients with AMD were recruited from April 2006 to March 2009 from 18 clinical trial sites in Japan. They were followed up for 5 years, as they continued to receive medical treatment. RESULTS: Of the 409 study eyes followed up for at least 1 year, 243 eyes (59...
December 9, 2017: Japanese Journal of Ophthalmology
https://www.readbyqxmd.com/read/29223946/-quality-of-the-exo-endocervical-sampling-in-the-prevention-of-uterine-cervix-cancer
#5
Anabela A Angeleri, Lili B Díaz, Gisela Coliva, Fernando Guerra, Luis A Palaoro, Adriana E Rocher
Cervical and vaginal cytology, Papanicolaou test (PAP), is the most effective test for screening of preneoplastic lesions, and cervical cancer prevention. Its sensitivity goes from 50 to 98%, according to different statistics, and this variation is related to the sampling procedure. A satisfactory smear should be taken from the transformation zone, the junction between endocervix and exocervix. According to Bethesda, metaplastic and/or endocervical cells should be observed under the microscope. The traditional PAP smear includes an exo-endocervical sampling using the Ayre spatula; however, only near 50% of the smears are representative of the transformation zone...
2017: Medicina
https://www.readbyqxmd.com/read/29223945/-heart-transplantation-in-an-hiv-infected-patient
#6
Pablo Mouras, Laura Barcán, César Belziti, Rodolfo Pizarro, Noelia Mañez, Ricardo Marenchino
Because of its own unfavourable evolution, HIV infection was until recently considered a contraindication for organ transplantation. The introduction of highly active antiretroviral therapy prolonged the life expectancy of these patients and allowed the manifestation of disorders directly or indirectly related to HIV infection, mainly liver, kidney and cardiovascular diseases. We present a case of cardiac transplantation due to dilated cardiomyopathy that was performed in a patient with a recently detected HIV infection...
2017: Medicina
https://www.readbyqxmd.com/read/29223932/pregnancy-related-knowledge-of-women-with-epilepsy-an-internet-based-survey-in-german-speaking-countries
#7
Carolin Dierking, Thomas Porschen, Uwe Walter, Johannes Rösche
There are several issues, which have to be acknowledged, when treating women with epilepsy (WWE). The need for counseling WWE in Germany with epilepsy on pregnancy-related matters was stressed in several papers and medical guidelines. Physicians treating WWE in Germany therefore should be aware of the information needs of their patients. We aimed to determine the level of pregnancy-related knowledge of WWE and their informational needs concerning pregnancy and childbirth issues in German-speaking countries by an internet-based survey...
December 7, 2017: Epilepsy & Behavior: E&B
https://www.readbyqxmd.com/read/29223883/analysis-of-mainland-japanese-and-okinawan-japanese-populations-using-the-precision-id-ancestry-panel
#8
Hiroaki Nakanishi, Vania Pereira, Claus Børsting, Toshimichi Yamamoto, Torben Tvedebrink, Masaaki Hara, Aya Takada, Kazuyuki Saito, Niels Morling
We typed 165 AIMs in 49 mainland Japanese and 47 Okinawa Japanese using the Precision ID Ancestry Panel (Thermo Fisher Scientific). None of the 165 SNPs showed significant deviation from Hardy-Weinberg equilibrium in the mainland Japanese. One SNP (rs3943253) showed significant deviation from Hardy-Weinberg equilibrium in Okinawa Japanese. Fisher's exact tests showed that the genotype frequencies of 14 loci were significantly different (p<0.05) between the two populations before correction for multiple testing...
December 6, 2017: Forensic Science International. Genetics
https://www.readbyqxmd.com/read/29223794/a-new-t2-lesion-in-a-patient-with-the-clinically-isolated-syndrome-does-not-necessarily-imply-a-conversion-to-multiple-sclerosis
#9
Fioravante Capone, Marco Puthenparampil, Carlo Augusto Mallio, Alessandra Ida Celia, Lucia Florio, Paolo Gallo, Vincenzo Di Lazzaro
In the follow-up of patients with the clinically isolated syndrome, both clinical and MRI findings should be carefully evaluated by clinicians to avoid misinterpretation and inappropriate diagnosis of multiple sclerosis. We describe a case of a patient with a previous diagnosis of clinically isolated syndrome who developed a new asymptomatic brain lesion at the MRI follow-up. The careful evaluation of clinical history and radiological findings allowed the correct diagnosis of cocaine-associated ischemic stroke...
December 7, 2017: Clinical Neurology and Neurosurgery
https://www.readbyqxmd.com/read/29223792/prediction-of-persistent-hemodynamic-depression-after-carotid-angioplasty-and-stenting-using-artificial-neural-network-model
#10
Jin Pyeong Jeon, Chulho Kim, Byoung-Doo Oh, Sun Jeong Kim, Yu-Seop Kim
OBJECTIVES: To assess and compare predictive factors for persistent hemodynamic depression (PHD) after carotid artery angioplasty and stenting (CAS) using artificial neural network (ANN) and multiple logistic regression (MLR) or support vector machines (SVM) models. PATIENTS AND METHODS: A retrospective data set of patients (n=76) who underwent CAS from 2007 to 2014 was used as input (training cohort) to a back-propagation ANN using TensorFlow platform. PHD was defined when systolic blood pressure was less than 90mmHg or heart rate was less 50 beats/min that lasted for more than one hour...
December 5, 2017: Clinical Neurology and Neurosurgery
https://www.readbyqxmd.com/read/29223789/medical-and-developmental-outcomes-of-bevacizumab-versus-laser-for-retinopathy-of-prematurity
#11
Kathleen A Kennedy, Helen A Mintz-Hittner
BACKGROUND: Infants with stage 3+ retinopathy of prematurity (ROP) in zone I or zone II posterior were randomized to initial treatment with bevacizumab or laser in a multicenter trial (BEAT-ROP). The purpose of this study was to assess the effects of bevacizumab on nonophthalmologic outcomes. METHODS: At one study site, inborn infants of <27 weeks' gestational age underwent medical and standardized neurologic and developmental assessments at 18-22 months' corrected age (age after expected date of full-term delivery)...
December 6, 2017: Journal of AAPOS: the Official Publication of the American Association for Pediatric Ophthalmology and Strabismus
https://www.readbyqxmd.com/read/29223725/transfusion-associated-circulatory-overload-a-survey-among-dutch-intensive-care-fellows
#12
R B Klanderman, I Attaye, J J Bosboom, D P Veelo, B F Geerts, A P J Vlaar
OBJECTIVES: Transfusion-associated circulatory overload (TACO) is a severe pulmonary transfusion reaction and leading cause of transfusion-related morbidity and mortality in Europe. TACO is of particular importance in critically ill patients, since they often receive blood transfusions and have multiple risk factors for TACO. This study investigates transfusion practices in patients at risk of developing TACO, and furthermore knowledge concerning risk factors, diagnoses and treatment strategies among Dutch intensive care unit (ICU) fellows...
December 6, 2017: Transfusion Clinique et Biologique: Journal de la Société Française de Transfusion Sanguine
https://www.readbyqxmd.com/read/29223707/reliability-of-two-techniques-and-training-level-of-the-observer-in-measuring-the-correction-angle-when-planning-a-high-tibial-osteotomy
#13
Julia Blackburn, Aneel Ansari, Andrew Porteous, James Murray
BACKGROUND: In high tibial osteotomy, planning is critical for achieving successful realignment. Any method selected needs to be reliable, with inter-observer and intra-observer correlation. A literature review demonstrated two distinct methods of planning for high tibial osteotomy. HYPOTHESIS: Both methods are precise and show excellent inter and intra-observer correlation. METHOD: Fifty consecutive weight-bearing long leg alignment antero-posterior (AP) radiographs were identified and planning undertaken on suitable radiographs using the methods of Puddu (method 1) and Miniaci (method 2)...
December 6, 2017: Knee
https://www.readbyqxmd.com/read/29223651/effects-of-the-rigid-gas-permeable-contact-lense-use-on-tear-and-ocular-surface-among-keratoconus-patients
#14
Cansu Yuksel Elgin, Guzin Iskeleli, Ovgu Aydin
PURPOSE: To investigate changes in tear and ocular surface of patients with keratoconus using rigid gas permeable contact lenses (RGPCL) and compare them against keratoconus patients who were not using lenses as well as a control group of healthy subjects. METHODS: 24 keratoconus patients using RGPCL (Group 1) 22 patients who were not using lenses (Group 3) and 21 healthy subjects (Group 3) were included in the study. Subjective complaints about the subjects' eyes have been investigated using the ocular-surface disease index (OSDI)...
December 6, 2017: Contact Lens & Anterior Eye: the Journal of the British Contact Lens Association
https://www.readbyqxmd.com/read/29223629/a-new-clinical-sign-of-lumbrical-plus%C3%A2-finger
#15
Frédéric A Schuind, Fabian Moungondo, Pierre Van Wetter
Paradoxical finger extension is the classical clinical presentation of the lumbrical plus syndrome. We report a new additional sign, increased metacarpophalangeal flexion of the involved finger when the patient tries to make a fist. Three cases of lumbrical tightness are discussed, illustrating this new sign in 3 different clinical settings. The new sign was present in all 3 cases. Lumbrical tenotomy corrected the paradoxical interphalangeal extension and partly the increased metacarpophalangeal flexion. The lumbrical tendon has a relatively high moment arm relative to the metacarpophalangeal joint, which could explain the basis of this clinical sign...
December 6, 2017: Journal of Hand Surgery
https://www.readbyqxmd.com/read/29223558/consumer-acceptance-of-minced-meat-patties-from-boars-in-four-european-countries
#16
M Aluwé, M Aaslyng, G Backus, M Bonneau, P Chevillon, J-E Haugen, L Meier-Dinkel, D Mörlein, M A Oliver, H M Snoek, F A M Tuyttens, M Font-I-Furnols
A consumer study was performed in four EU countries to further clarify the acceptability of meat with boar taint. In Denmark, France, Italy and Poland, a total of 476 female consumers evaluated 8 meat patties from boars with varying levels of skatole (0.10-0.40μg/g fat tissue) and androstenone (0.47-2.00 μg/g fat tissue), in a pair-wise comparison with patties from castrates. Boar meat patties were always less preferred than the castrate meat patties, regardless of the level of androstenone and skatole. Acceptability of the boar meat patties decreased with increasing skatole level...
November 28, 2017: Meat Science
https://www.readbyqxmd.com/read/29223522/custom-made-titanium-3d-printed-interbody-cages-for-treatment-of-osteoporotic-fracture-related-spinal-deformity
#17
Timothy Siu, Jeffrey M Rogers, Kainu Lin, Robert Thompson, Mark Owbridge
BACKGROUND: Advances in minimally invasive interbody fusion have greatly enhanced surgeons' capability to correct adult spinal deformity with reduced morbidity. However, the feasibility of such approaches is limited in patients with previous osteoporotic fractures as the resultant vertebral deformity renders the endplate geometry incongruous with conventional interbody implants. Current 3D printing technology offers a novel solution by fabricating custom-made implants tailored to individual anatomy...
December 6, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/29223238/pupillary-block-glaucoma-secondary-to%C3%A2-central-port-occlusion-following-insertion-of-a-phakic-implantable-copolymer-lens
#18
Felix Gonzalez-Lopez, Rafael Bilbao-Calabuig, Ricardo Alen, Blas Mompean
A 28-year-old woman had uneventful implantation of a phakic intraocular lens (pIOL) in her left eye (Visian ICL, EVO+ model, 13.2, -7.50 diopters) to correct myopia. Six days after the procedure, she presented with herniation of the iris. Surgical reduction was carried out successfully through the previous peripheral corneal paracentesis. On the following day, the patient reported ocular pain and blurry vision. Examination showed a shallow anterior chamber, moderate diffuse corneal edema, and ocular hypertension...
November 2017: Journal of Cataract and Refractive Surgery
https://www.readbyqxmd.com/read/29223235/determining-total-corneal-power-after-small-incision-lenticule-extraction-in-myopic-eyes
#19
Pinghui Wei, Yan Wang, Tommy C Y Chan, Alex L K Ng, George P M Cheng, Vishal Jhanji
PURPOSE: To evaluate the methods to correct corneal power after myopic small-incision lenticule extraction (SMILE) and to estimate the preoperative corneal power based on postoperative values. SETTING: Tianjin Eye Hospital, Tianjin, China. DESIGN: Retrospective case series. METHODS: Equivalent keratometry (K) and mean K readings were obtained with the Pentacam HR. The clinical history method was used to calculate the theoretical postoperative K, which was then compared with equivalent K readings...
November 2017: Journal of Cataract and Refractive Surgery
https://www.readbyqxmd.com/read/29223233/outcomes-of-retreatment-after-hyperopic-laser-in%C3%A2-situ-keratomileusis
#20
Andreas Frings, Elisa Intert, Johannes Steinberg, Vasyl Druchkiv, Stephan J Linke, Toam Katz
PURPOSE: To evaluate the efficacy, predictability, and safety of laser in situ keratomileusis (LASIK) retreatment in eyes with hyperopia. SETTING: Multicenter refractive surgery centers and University Hospital, Germany. DESIGN: Retrospective case series. METHODS: This multicenter study included hyperopic patients with a preoperative difference between cycloplegic and manifest refraction of 1.00 diopter (D) or less who had LASIK retreatment based on manifest refraction...
November 2017: Journal of Cataract and Refractive Surgery
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