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JOURNAL ARTICLE
Eudora L Olsen, Ayana K April-Sanders, Hector R Bird, Glorisa J Canino, Cristiane S Duarte, Shakira F Suglia
IMPORTANCE: Sleep quality is a known marker of overall health. Studies suggest that adverse childhood experiences (ACEs) are associated with sleep disturbances among children and adults. OBJECTIVE: To examine the association of retrospective and prospective ACEs with sleep quality among a cohort of Puerto Rican young adults from 2 sociocultural contexts. DESIGN, SETTING, AND PARTICIPANTS: This prospective cohort study used data from the Boricua Youth Study (BYS), a population-based study representing Puerto Rican children from the South Bronx, New York, and Puerto Rico conducted from August 2000 to August 2003...
April 1, 2024: JAMA Network Open
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JOURNAL ARTICLE
Ling-Ling Xie, Shao-Jun Wang, Bo Xiao, Zheng-Jun Wang, Zhi-Peng Guo, Xiao-Fei Guo, Shuang Luo, Rui Li, Jia-Hui Xia, Meng-Jie Lan, Sheng-Qiu Yang
Exploring the effects of ant nests on soil CH4 emissions in the secondary tropical forests is of great scientific significance to understand the contribution of soil faunal activities to greenhouse gas emissions. With static chamber-gas chromatography method, we measured the dry-wet seasonal dynamics of CH4 emissions from ant nests and control soils in the secondary forest of Syzygium oblatum communities in Xishuangbanna. We also examined the linkages of ant-mediated changes in functional microbial diversity and soil physicochemical properties with CH4 emissions...
March 18, 2024: Ying Yong Sheng Tai Xue Bao, the Journal of Applied Ecology
#3
JOURNAL ARTICLE
Grace W K Ho, Ko Ling Chan, Thanos Karatzias, Philip Hyland, Hong Wang Fung, Mark Shevlin
The present study aimed to report the prevalence of ICD-11 posttraumatic stress disorder (PTSD) and complex PTSD (CPTSD) in the general adult Hong Kong population, and examine the validity of the Chinese International Trauma Questionnaire (ITQ). This descriptive cross-sectional population-based telephone survey included a representative sample of 1070 non-institutionalized permanent Hong Kong residents ages 18-64 years. Participants provided responses to the Chinese version of the ITQ, and measures of adverse childhood experiences (ACEs), depression, anxiety, and stress...
April 10, 2024: Asian Journal of Psychiatry
#4
JOURNAL ARTICLE
Shuang Xu, Rong Zhao, Jiao Sun, Yuhuan Sun, Guangjian Xu, Fayuan Wang
Microplastics (MPs) are emerging contaminants found globally. However, their effects on soil-plant systems in salt-affected habitats remain unknown. Here, we examined the effects of polyethylene (PE) and polylactic acid (PLA) on soil properties, maize performance, and bacterial communities in soils with different salinity levels. Overall, MPs decreased soil electrical conductivity and increased NH4 + -N and NO3 - -N contents. Adding NaCl alone had promoting and inhibitive effects on plant growth in a concentration-dependent manner...
April 16, 2024: Journal of Hazardous Materials
#5
EDITORIAL
Matthieu Legrand
Many patients undergoing surgical procedures have a history of hypertension, diabetes mellitus, heart failure, or a combination. Often, these conditions involve the chronic use of a renin-angiotensin system inhibitor, including angiotensin-converting enzyme inhibitors (ACEIs) or angiotensin receptor blockers (ARBs). Observational studies have suggested that continuing ACEIs/ARBs before major noncardiac surgery can increase the risk of intraoperative hypotension, which might drive postoperative complications such as acute kidney injury, myocardial injury, or stroke...
May 2024: British Journal of Anaesthesia
#6
JOURNAL ARTICLE
Marvin A Solberg, Julie A M J Kurzer
BACKGROUND: Adverse childhood experiences (ACEs) are known determinants of negative health outcomes. Sexual and gender minority (SGM) individuals have higher ACE scores than non-SGM individuals. The SGM-ACE scale was developed to better assess this population but is not yet validated in SGM subgroups. AIMS: This study aims to validate the sexual and gender minority adverse childhood experiences (SGM-ACE) scale among sexual minority men (SMM) and sexual minority women (SMW), while testing measurement invariance across both groups...
April 20, 2024: Journal of the American Psychiatric Nurses Association
#7
JOURNAL ARTICLE
Nishad Sultana, S N Nagesha, C N Lakshminarayana Reddy, B N Ramesh, S Shyamalamma, K S Shashidhara, K M Satish, C Pradeep, G D Vidyadhar
The novel coronavirus SARS-CoV-2 resulted in a significant worldwide health emergency known as the COVID-19 pandemic. This crisis has been marked by the widespread of various variants, with certain ones causing notable apprehension. In this study, we harnessed computational techniques to scrutinize these Variants of Concern (VOCs), including various Omicron subvariants. Our approach involved the use of protein structure prediction algorithms and molecular docking techniques, we have investigated the effects of mutations within the Receptor Binding Domain (RBD) of SARS-CoV-2 and how these mutations influence its interactions with the human angiotensin-converting enzyme 2 (hACE-2) receptor...
April 19, 2024: Virology Journal
#8
JOURNAL ARTICLE
Matthew S Davids, Jeff P Sharman, Paolo Ghia, Jennifer A Woyach, Toby A Eyre, Wojciech Jurczak, Tanya Siddiqi, Paulo A Palhares de Miranda, Mina Shahkarami, Anna Maria Butturini, Ugochinyere Emeribe, John C Byrd
Before targeted therapies, patients with higher-risk chronic lymphocytic leukemia (CLL) defined as del(17p) and/or TP53 mutation (TP53m), unmutated immunoglobulin heavy chain variable region genes (uIGHV), or complex karyotype (CK) had poorer prognosis with chemoimmunotherapy. Bruton tyrosine kinase inhibitors (BTKis) have demonstrated benefit in higher-risk patient populations with CLL in individual trials. To better understand the impact of the second-generation BTKi acalabrutinib, we pooled data from 5 prospective clinical studies of acalabrutinib as monotherapy or in combination with obinutuzumab (ACE-CL-001, ACE-CL-003, ELEVATE-TN, ELEVATE-RR, and ASCEND) in patients with higher-risk CLL in treatment-naive (TN) or relapsed/refractory (R/R) cohorts...
April 19, 2024: Blood Advances
#9
JOURNAL ARTICLE
Jiayi Chen, Hongwu Ji, Jing Luo, Di Zhang, Shucheng Liu
In the study, papain was used to hydrolyze tilapia (Oreochromis mossambicus) skin to obtain a tilapia skin hydrolysate (TSH) with dual angiotensin-converting enzyme (ACE) and dipeptidyl peptidase IV (DPP-IV) inhibitory activities. The resulting TSH was sequentially fractionated by ultrafiltration, size exclusion separation chromatography, and reverse-phase high-performance liquid chromatography. Its inhibitory effects on ACE and DPP-IV were determined by commercial reagent kits. Two peptides purified from TSH were identified as Gly-Pro-Leu-Gly-Ala-Leu (GPLGAL) and Lys-Pro-Ala-Gly-Asn (KPAGN) by the ultra-performance liquid chromatography-tandem mass spectrometry (UPLC-MS/MS)...
April 18, 2024: Journal of Food Science
#10
JOURNAL ARTICLE
Daniel E Leisman, Damian R Handisides, Laurence W Busse, Mark C Chappell, Lakhmir S Chawla, Michael R Filbin, Marcia B Goldberg, Kealy R Ham, Ashish K Khanna, Marlies Ostermann, Michael T McCurdy, Christopher D Adams, Tony N Hodges, Rinaldo Bellomo
BACKGROUND: Angiotensin-converting enzyme inhibitor (ACEi) and angiotensin receptor blockers (ARB) medications are widely prescribed. We sought to assess how pre-admission use of these medications might impact the response to angiotensin-II treatment during vasodilatory shock. METHODS: In a post-hoc subgroup analysis of the randomized, placebo-controlled, Angiotensin Therapy for High Output Shock (ATHOS-3) trial, we compared patients with chronic angiotensin-converting enzyme inhibitor (ACEi) use, and patients with angiotensin receptor blocker (ARB) use, to patients without exposure to either ACEi or ARB...
April 18, 2024: Critical Care: the Official Journal of the Critical Care Forum
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MULTICENTER STUDY
Michael D Keller, Patrick J Hanley, Yueh-Yun Chi, Paibel Aguayo-Hiraldo, Christopher C Dvorak, Michael R Verneris, Donald B Kohn, Sung-Yun Pai, Blachy J Dávila Saldaña, Benjamin Hanisch, Troy C Quigg, Roberta H Adams, Ann Dahlberg, Shanmuganathan Chandrakasan, Hasibul Hasan, Jemily Malvar, Mariah A Jensen-Wachspress, Christopher A Lazarski, Gelina Sani, John M Idso, Haili Lang, Pamela Chansky, Chase D McCann, Jay Tanna, Allistair A Abraham, Jennifer L Webb, Abeer Shibli, Amy K Keating, Prakash Satwani, Pawel Muranski, Erin Hall, Michael J Eckrich, Evan Shereck, Holly Miller, Ewelina Mamcarz, Rajni Agarwal, Satiro N De Oliveira, Mark T Vander Lugt, Christen L Ebens, Victor M Aquino, Jeffrey J Bednarski, Julia Chu, Suhag Parikh, Jennifer Whangbo, Michail Lionakis, Elias T Zambidis, Elizabeth Gourdine, Catherine M Bollard, Michael A Pulsipher
Viral infections remain a major risk in immunocompromised pediatric patients, and virus-specific T cell (VST) therapy has been successful for treatment of refractory viral infections in prior studies. We performed a phase II multicenter study (NCT03475212) for the treatment of pediatric patients with inborn errors of immunity and/or post allogeneic hematopoietic stem cell transplant with refractory viral infections using partially-HLA matched VSTs targeting cytomegalovirus, Epstein-Barr virus, or adenovirus...
April 18, 2024: Nature Communications
#12
REVIEW
Norbert Karl Mülleneisen, Jens Callegari, Friederike Sophie Magnet
No abstract text is available yet for this article.
April 2024: MMW Fortschritte der Medizin
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JOURNAL ARTICLE
Jiaxin Zhang, S Ghazaleh Dashti, John B Carlin, Katherine J Lee, Margarita Moreno-Betancur
In the context of missing data, the identifiability or "recoverability" of the average causal effect (ACE) depends not only on the usual causal assumptions but also on missingness assumptions that can be depicted by adding variable-specific missingness indicators to causal diagrams, creating missingness directed acyclic graphs (m-DAGs). Previous research described canonical m-DAGs, representing typical multivariable missingness mechanisms in epidemiological studies, and examined mathematically the recoverability of the ACE in each case...
April 2024: Biometrical Journal. Biometrische Zeitschrift
#14
Vasudevan Ramachandran, Nur Afiqah Mohamad, Mohd Nazil Salleh, Wan Aliaa Wan Sulaiman, Liyana Najwa Inche Mat, Mohd Hazmi Mohamed, Ching Siew Mooi, Abdul Hanif Khan Yusof Khan, Hamidon Basri, Pannerselvam Periasamy, Vajiravelu Suganthi, Narenkumar Jayaraman
INTRODUCTION: Vascular dementia (VaD), a neurocognitive impairment directly related to vascular injury, is the second most common cause of age-related dementia. Although numerous studies have investigated candidate genetic polymorphisms associated with VaD in Asia, the genetics of VaD remains unclear. METHODS: This review provides an updated meta-analysis of genetic polymorphisms associated with VaD in Asians, using the PRISMA guidelines. Published literature up to May 2021 was extracted from the PubMed, Scopus, Ovid, and EBSCO host databases...
April 18, 2024: Dementia and Geriatric Cognitive Disorders
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JOURNAL ARTICLE
Roland von Känel, Mary Princip, Sarah A Holzgang, Andreas A Giannopoulos, Philipp A Kaufmann, Ronny R Buechel, Claudia Zuccarella-Hackl, Aju P Pazhenkottil
OBJECTIVE: Physicians face documented challenges to their mental and physical well-being, particularly in the forms of occupational burnout and cardiovascular disease. This study examined the previously under-researched intersection of early life stressors, prolonged occupational stress, and cardiovascular health in physicians. METHODS: Participants were 60 practicing male physicians, 30 with clinical burnout, defined by the Maslach Burnout Inventory, and 30 non-burnout controls...
April 15, 2024: Journal of Psychosomatic Research
#16
JOURNAL ARTICLE
Grant Benham, Ruby Charak, Ines Cano-Gonzalez, Joceline Mena Teran, Jordan Kenemore
Insomnia is common in college students and linked to poorer mental and physical health. There is growing evidence that adverse childhood experiences (ACEs) may contribute to insomnia in adulthood. However, beyond the need for additional replication of these findings, there is a need to identify underlying mechanisms that plausibly connect the two experiences. Based on a serial mediation model, the current study examined the role of two theoretically informed mediators: recent stressful life events and perceived stress...
April 18, 2024: Behavioral Medicine
#17
JOURNAL ARTICLE
Berhe W Sahle, Nicola J Reavley, Amy J Morgan, Marie Bee Hui Yap, Andrea Reupert, Anthony F Jorm
This study aims to: (i) examine the association between adverse childhood experiences (ACEs) and elevated anxiety and depressive symptoms in adolescents; and (ii) estimate the burden of anxiety and depressive symptoms attributable to ACEs.Data were analyzed from 3089 children followed between Waves 1 (age 4-5 years) and 7 (16-17 years) of the Longitudinal Study of Australian Children. Logistic regression was used to estimate the associations between ACEs and child-reported elevated anxiety and depressive symptoms at age 16-17...
April 17, 2024: BMC Psychiatry
#18
JOURNAL ARTICLE
Fengwei Hao, Pengda Li, Zhide Liang, Jiaxian Geng
Many studies have explored the association between adverse childhood experiences (ACEs) and Internet addiction (IA), yet the research findings on the association between them are inconclusive. We conducted a systematic search on 7 databases to identify the relevant studies published until January 2023, and analyzed the findings from 37 studies across 12 countries involving 45,364 participants aged 8 to 67 years (51 % women). Results indicated a positive correlation (r = 0.21) was found between ACE and IA around the world, which differed among continents...
April 16, 2024: Acta Psychologica
#19
JOURNAL ARTICLE
Elizabeth A Stinson, Ryan M Sullivan, Gabriella Y Navarro, Alexander L Wallace, Christine L Larson, Krista M Lisdahl
Adolescence is characterized by dynamic neurodevelopment, which poses opportunities for risk and resilience. Adverse childhood experiences (ACEs) confer additional risk to the developing brain, where ACEs have been associated with alterations in functional magnetic resonance imaging (fMRI) BOLD signaling in brain regions underlying inhibitory control. Socioenvironmental factors like the family environment may amplify or buffer against the neurodevelopmental risks associated with ACEs. Using baseline to Year 2 follow-up data from the Adolescent Brain Cognitive Development (ABCD) Study, the current study examined how ACEs relate to fMRI BOLD signaling during successful inhibition on the Stop Signal Task in regions associated with inhibitory control and examined whether family conflict levels moderated that relationship...
April 9, 2024: Developmental Cognitive Neuroscience
#20
JOURNAL ARTICLE
Wenyu Cui, Fuchun Chen, Zhaoyue Sun, Caifang Cui, Ben Xu, Weijun Shen, Fachun Wan, Anwei Cheng
BACKGROUND: Grape peels, the main by-products of wine processing, are rich in bioactive ingredients of phenolics, including proanthocyanidins, flavonoids and anthocyanins. Phenolics have the function of regulating intestinal microbiota and promoting intestinal health. From the perspective of the dietary nutrition of grape peel phenolics (GPP), this study was to investigate the influence of GPP on the composition and metabolism of human gut microbiota during in vitro fermentation. RESULTS: The results indicated that GPP could decrease pH and promote the production of short-chain fatty acids (SCFAs)...
April 16, 2024: Journal of the Science of Food and Agriculture
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