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https://www.readbyqxmd.com/read/29677278/annals-graphic-medicine-an-apple-a-day
#1
Michael Koerner, Eliza Fredette, Trudy A Watt, Peter Lloyd Jones
No abstract text is available yet for this article.
April 17, 2018: Annals of Internal Medicine
https://www.readbyqxmd.com/read/29675998/biomaterial-granules-used-for-filling-bone-defects-constitute-3d-scaffolds-porosity-microarchitecture-and-molecular-composition-analyzed-by-microct-and-raman-microspectroscopy
#2
Baptiste Arbez, Jean-Daniel Kün-Darbois, Thierry Convert, Bernard Guillaume, Philippe Mercier, Laurent Hubert, Daniel Chappard
Biomaterials are used in the granular form to fill small bone defects. Granules can be prepared with a grinder from trabecular bone samples or provided as synthetic biomaterials by industry. Granules occupy the 3D-space and create a macroporosity allowing invasion of vascular and bone cells when the inter-granular pores are larger than 300 µm. We compared the 3D-porosity of granule stacks obtained or prepared with nine biomaterials Osteopure® , Lubboc® , Bio-Oss® , CopiOs® , TCP Dental® , TCP Dental HP® , KeraOs® , and TCH® in comparison with that of human trabecular bone...
April 19, 2018: Journal of Biomedical Materials Research. Part B, Applied Biomaterials
https://www.readbyqxmd.com/read/29675920/long-term-feasibility-and-biocompatibility-of-directly-microsurgically-implanted-intrafascicular-electrodes-in-free-roaming-rabbits
#3
Gehua Zhen, Huanwen Chen, Shin-Yi Tsai, Jian Zhang, Tongyi Chen, Xiaofeng Jia
Novel neural interfaces capable of reliably capturing electrical signals are crucial for the development of prostheses. Longitudinal intrafascicular electrodes (LIFEs) have been proposed as a promising technology, and their feasibility and biocompatibility need to be investigated for long-term implantation. In this study, custom-designed 95%Pt-5%Ir intrafascicular electrodes were implanted into the sciatic nerves of 14 rabbits using our novel direct microsurgical technique. The biocompatibility and their ability to record electrophysiological signals were serially investigated up to 9 months after implantation...
April 19, 2018: Journal of Biomedical Materials Research. Part B, Applied Biomaterials
https://www.readbyqxmd.com/read/29675868/control-efficacy-of-ca-containing-foliar-fertilizers-on-bitter-pit-in-bagged-fuji-apple-and-effects-on-the-ca-and-n-contents-of-apple-fruits-and-leaves
#4
Xian-Mei Yu, Jin-Zheng Wang, Pei-Xian Nie, Xaio-Min Xue, Gui-Ping Wang, Miao An
BACKGROUND: The preharvest application of Ca-containing foliar fertilizers can reduce bitter pit (BP) incidence in apples and improve fruit quality by increasing the Ca content and decreasing both the N content and the N/Ca ratio in fruits. In this study, we aimed to investigate the control efficacy of Ca-containing fertilizers on BP incidence and the effects on the Ca and N contents in bagged 'Fuji' apple by spraying the foliar fertilizer containing calcium chloride (CaCl2 ), calcium nitrate [Ca(NO3 )2 ] or calcium formate [Ca(HCOO)2 ] at early stage [5 days after full bloom (DAFB) + 40 DAFB] and at late stage (80 DAFB + 125 DAFB)...
April 20, 2018: Journal of the Science of Food and Agriculture
https://www.readbyqxmd.com/read/29675859/fabrication-of-superparamagnetic-nanofibrous-poly-l-lactic-acid-%C3%AE-fe-2-o-3-microspheres-for-cell-carriers
#5
Moyuan Qu, Wenqian Xiao, Jiarong Tian, Song Wang, Hong Li, Xue Liu, Xiaoling Yang, Bo Li, Xiaoling Liao
Nanofibrous poly(l-lactic acid) (PLLA) microspheres are extensively studied to be used as cell carriers in the field of tissue engineering because the unique structure can promote cell proliferation and migration. But as injectable scaffold materials, PLLA microspheres easily run off to the soft tissue space because of the lack of cohesive force. It will affect the treatment efficiency and even cause additional inflammatory response. In order to overcome this disadvantage, superparamagnetic γ-Fe2 O3 nanoparticles assisted with oxidative polymerization of dopamine were used for surface modification of PLLA microspheres in this study...
April 19, 2018: Journal of Biomedical Materials Research. Part B, Applied Biomaterials
https://www.readbyqxmd.com/read/29675811/systematic-analysis-and-comparison-of-the-phd-finger-gene-family-in-chinese-pear-pyrus-bretschneideri-and-its-role-in-fruit-development
#6
Yunpeng Cao, Yahui Han, Dandan Meng, Muhammad Abdullah, Dahui Li, Qing Jin, Yi Lin, Yongping Cai
PHD-finger proteins, which belongs to the type of zinc finger family, and that play an important role in the regulation of both transcription and the chromatin state in eukaryotes. Currently, PHD-finger proteins have been well studied in animals, while few studies have been carried out on their function in plants. In the present study, 129 non-redundant PHD-finger genes were identified from 5 Rosaceae species (pear, apple, strawberry, mei, and peach); among them, 31 genes were identified in pear. Subsequently, we carried out a bioinformatics analysis of the PHD-finger genes...
April 20, 2018: Functional & Integrative Genomics
https://www.readbyqxmd.com/read/29674840/strong-convergence-theorems-for-coordinatewise-negatively-associated-random-vectors-in-hilbert-space
#7
Xiang Huang, Yongfeng Wu
In this work, some strong convergence theorems are established for weighted sums of coordinatewise negatively associated random vectors in Hilbert spaces. The results obtained in this paper improve and extend the corresponding ones of Huan et al. (Acta Math. Hung. 144(1):132-149, 2014) as well as correct and improve the corresponding one of Ko (J. Inequal. Appl. 2017:290, 2017).
2018: Journal of Inequalities and Applications
https://www.readbyqxmd.com/read/29674380/odor-discrimination-learning-in-the-indian-greater-short-nosed-fruit-bat-cynopterus-sphinx-differential-expression-of-egr-1-c-fos-and-pp-1-in-the-olfactory-bulb-amygdala-and-hippocampus
#8
Murugan Mukilan, Wieslaw Bogdanowicz, Ganapathy Marimuthu, Koilmani Emmanuvel Rajan
Activity-dependent expression of immediate-early genes (IEGs) is induced by exposure to odor. The present study was designed to investigate whether there is differential expression of IEGs ( Egr-1 , C-fos ) in the brain region mediating olfactory memory in the Indian greater short-nosed fruit bat Cynopterus sphinx We assumed that differential expression of IEGs in different brain regions may orchestrate a preference odor (PO) and aversive odor (AO) memory in C. sphinx We used preferred (0.8% wt/wt of cinnamon powder) and aversive (0...
April 19, 2018: Journal of Experimental Biology
https://www.readbyqxmd.com/read/29674247/apple-peel-polyphenols-reduce-mitochondrial-dysfunction-in-mice-with-dss-induced-ulcerative-colitis
#9
Pantea Rahmani Yeganeh, Jade Leahy, Schohraya Spahis, Natalie Patey, Yves Desjardins, Denis Roy, Edgard Delvin, Carole Garofalo, Jean-Philippe Leduc-Gaudet, David St-Pierre, Jean-François Beaulieu, André Marette, Gilles Gouspillou, Emile Levy
Inflammatory bowel diseases (IBDs) are multifaceted and relapsing immune disorders, which necessitate long-term dependence on powerful drugs. As the use of natural product-based therapies has emerged as a promising intervention, the present study aimed to further characterize dried apple peel powder (DAPP) mechanisms of action and evaluate the preventive and curative effects of DAPP on mitochondrial functions in a murine model. Induction of intestinal inflammation in mice is performed by oral administration of the dextran sodium sulfate (DSS) at 2...
March 21, 2018: Journal of Nutritional Biochemistry
https://www.readbyqxmd.com/read/29673958/binary-grafted-chitosan-film-synthesis-characterization-antibacterial-activity-and-prospects-for-food-packaging
#10
Deepak Kumar, Pramendra Kumar, Jyoti Pandey
The antimicrobial binary grafted chitosan film [chit-g-Poly (An-co-Am)] was prepared by grafting of acrylonitrile and acrylamide on to chitosan via microwave initiated graft copolymerization. The grafting of acrylonitrile and acrylamide onto chitosan backbone was confirmed by FTIR, XRD, SEM and TGA/DTA/DTG analytical techniques. The binary grafted chitosan film possessed efficient antimicrobial activity against three tested strains, i.e. Escherichia coli, Staphylococcus aureus and Pseudomonas aeruginosa. The prepared binary grafted chitosan film was tested for packaging apple and guava to prevent microbial infection and extend their shelf life...
April 16, 2018: International Journal of Biological Macromolecules
https://www.readbyqxmd.com/read/29671087/severe-adverse-reactions-following-ketoconazole-fluconazole-and-environmental-exposures-a-case-report
#11
Allan Lieberman, Luke Curtis
In this case report, we describe a 66-year-old man who developed multiple adverse reactions beginning at age 56 after exposure to several azole antifungal drugs including ketoconazole and fluconazole. He also had a history of more than 40 years exposure to chemicals including pesticides, wood preservatives, fertilizers, and welding chemicals. His reactions involved dehydration (requiring several liters of intravenous fluids in less than an hour to alleviate this condition), angioedema, nausea, tinnitus, hypotension, and difficulty breathing...
April 18, 2018: Drug Safety—Case Reports
https://www.readbyqxmd.com/read/29669534/long-term-effects-of-comprehensive-school-health-on-health-related-knowledge-attitudes-self-efficacy-health-behaviours-and-weight-status-of-adolescents
#12
Nicole Naadu Ofosu, John Paul Ekwaru, Kerry Ann Bastian, Sarah A Loehr, Kate Storey, John C Spence, Paul J Veugelers
BACKGROUND: APPLE Schools is a Comprehensive School Health (CSH) project, started in schools in socioeconomically disadvantaged areas where dietary habits are poor, physical activity (PA) levels are low, and obesity rates are high. Earlier research showed program effects whereby energy intake, PA and weight status of students in APPLE Schools had reached similar levels as that of students in other schools. However, it is unknown whether the effects of CSH are sustained when children grow into adolescents...
April 18, 2018: BMC Public Health
https://www.readbyqxmd.com/read/29668962/mass-trapping-codling-moth-cydia-pomonella-lepidopteran-torticidae-using-a-kairomone-lure-reduces-fruit-damage-in-commercial-apple-orchards
#13
Benjamin D Jaffe, Christelle Guédot, Peter J Landolt
Codling moth Cydia pomonella L. (Lepidoptera: Tortricidae) is a major pest of pome fruits worldwide. Fruit is damaged by larval feeding, and numbers of larvae are directly related to the numbers of females in the preceding generation. In Pacific Northwest, apple orchards, C. pomonella are generally managed with insecticides and mating disruption. However, additional control methods are needed when these treatments fail or are undesirable. Using a three-component kairomone lure that attracts both sexes, we mass-trapped C...
April 16, 2018: Journal of Economic Entomology
https://www.readbyqxmd.com/read/29668869/multistate-comparison-of-attractants-and-the-impact-of-fruit-development-stage-on-trapping-drosophila-suzukii-diptera-drosophilidae-in-raspberry-and-blueberry
#14
Benjamin D Jaffe, Alina Avanesyan, Harit K Bal, Yan Feng, Joshua Grant, Matthew J Grieshop, Jana C Lee, Oscar E Liburd, Elena Rhodes, Cesar Rodriguez-Saona, Ashfaq A Sial, Aijun Zhang, Christelle Guédot
Spotted-wing drosophila, Drosophila suzukii Matsumura (Diptera: Drosophilidae), is an invasive pest of soft-skinned fruits across the globe. Effective monitoring is necessary to manage this pest, but suitable attractants are still being identified. In this study, we combined lures with fermenting liquid baits to improve D. suzukii trapping specificity and attractiveness. We also measured the efficiency and specificity of baits/lures during different times of the season; the reproductive status of females among baits/lures; and the effects of locations and crop type on these response variables...
April 14, 2018: Environmental Entomology
https://www.readbyqxmd.com/read/29667261/apple-s-rnase-interacts-with-an-actin-binding-protein-mdmvg-to-reduce-pollen-tube-growth-by-inhibiting-its-actin-severing-activity-at-the-early-stage-of-self-pollination-induction
#15
Qing Yang, Dong Meng, Zhaoyu Gu, Wei Li, Qiuju Chen, Yang Li, Hui Yuan, Jie Yu, Chunsheng Liu, Tianzhong Li
In S-RNase-mediated self-incompatibility (SI), S-RNase secreted from the style destroys the actin cytoskeleton of the self-pollen tubes, eventually halting its growth, but the mechanism remains unclear. In vitro biochemical assays revealed that S-RNase does not bind or sever filamentous actin (F-actin). In apple (Malus×domestica), we identified an actin-binding protein containing myosin, villin and GRAM, MdMVG, that physically interacts with S-RNase and directly binds and severs F-actin. Immunofluorescence assays and total internal reflection fluorescence microscopy (TIRFM) indicated that S-RNase inhibits the F-actin-severing activity of MdMVG in vitro...
April 18, 2018: Plant Journal: for Cell and Molecular Biology
https://www.readbyqxmd.com/read/29667033/tri11-tri3-and-tri4-genes-are-required-for-trichodermin-biosynthesis-of-trichoderma-brevicompactum
#16
Xuping Shentu, Jiayi Yao, Xiaofeng Yuan, Linmao He, Fan Sun, Kozo Ochi, Xiaoping Yu
Trichoderma brevicompactum and T. arundinaceum both can synthesize trichodermin with strong antifungal activity and high biotechnological value. The two Trichoderma species have a tri cluster, which includes seven genes (tri14, tri12, tri11, tri10, tri3, tri4, and tri6) that encode transport and regulatory enzymes required for the biosynthesis of trichodermin. Here, we isolated T. brevicompactum 0248 transformants with disrupted tri11, tri4, or tri3 gene. We also described the effect of tri11, tri3, or tri4 deletion on the expression of other genes in the tri cluster...
April 17, 2018: AMB Express
https://www.readbyqxmd.com/read/29667016/inflammation-and-the-risk-of-atrial-high-rate-episodes-ahres-in-patients-with-cardiac-implantable-electronic-devices
#17
Daniele Pastori, Kazuo Miyazawa, Yanguang Li, Farhan Shahid, Hussein Hado, Gregory Y H Lip
INTRODUCTION: Atrial high-rate episodes (AHREs) are associated with an increased risk of developing atrial fibrillation and thromboembolism. The characteristics of 'real world' patients developing AHREs are poorly known. METHODS: We included 496 consecutive patients with cardiac implantable electronic devices (CIEDs). Primary endpoint was occurrence of AHREs, defined as > 175 bpm and lasting > 5 min, in a median follow-up of 16.5 (IQR 3.9-38.6) months (1082...
April 17, 2018: Clinical Research in Cardiology: Official Journal of the German Cardiac Society
https://www.readbyqxmd.com/read/29666835/aptamers-and-apple-pies-a-mini-review-of-psma-aptamers-and-lessons-from-donald-s-coffey
#18
REVIEW
Shawn E Lupold
This mini-review article is part of a special issue dedicated to Donald S. Coffey, a pioneer translational research scientist, exemplary mentor, and leader in urologic and urologic oncology research. This article first briefly reflects on life and scientific lessons from Don Coffey. It then reviews the development of two prostate cancer targeting RNA aptamers, xPSM-A9 and xPSM-A10, through in vitro selection for aptamers that bind to the extracellular domain of the Prostate Specific Membrane Antigen (PSMA)...
2018: American Journal of Clinical and Experimental Urology
https://www.readbyqxmd.com/read/29666529/natural-preservatives-for-superficial-scald-reduction-and-enhancement-of-protective-phenolic-linked-antioxidant-responses-in-apple-during-post-harvest-storage
#19
Dipayan Sarkar, Chandrakant Ankolekar, Duane Greene, Kalidas Shetty
Superficial scald during post-harvest storage is a serious problem for long-term preservation and shelf-life of some apple and pear cultivars. Development of superficial scald and related physiological disorders such as enzymatic and non-enzymatic browning are associated in part with oxidative breakdown and redox imbalance. Therefore, targeting natural antioxidants from food-grade sources as post-harvest treatment to reduce superficial scald has merit. Such natural antioxidants can potentially counter oxidation-linked damages associated with superficial scald through stimulation of antioxidant enzyme responses and biosynthesis of less-oxidized phenolics involving protective redox-linked pathway such as proline-associated pentose phosphate pathway...
May 2018: Journal of Food Science and Technology
https://www.readbyqxmd.com/read/29666515/effect-of-fiber-sources-on-fatty-acids-profile-glycemic-index-and-phenolic-compound-content-of-in-vitro-digested-fortified-wheat-bread
#20
Marcin Andrzej Kurek, Jarosław Wyrwisz, Sabina Karp, Agnieszka Wierzbicka
In this study, some dietary fiber (DF) sources were investigated as fortifiers of wheat bread: oat (OB), flax (FB), and apple (AB). Adding oat and flax fibers to bread significantly changed the fatty acid profiles. OB was highest in oleic acid (33.83% of lipids) and linoleic acid (24.31% of lipids). Only in FB, γ-linolenic fatty acid was present in a significant amount-18.32%. The bioaccessibility trails revealed that the DF slow down the intake of saturated fatty acids. PUFA were least bioaccessible from all fatty acids groups in the range of (72% in OB to 87% in FB)...
May 2018: Journal of Food Science and Technology
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