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https://www.readbyqxmd.com/read/28945061/a-comparative-study-of-cfd-of-canine-model-of-common-carotid-fusiform-aneurysm-and-vertebrobasilar-fusiform-aneurysm-in-human-patients
#1
Shewei Guo, Peng Jiang, Jian Liu, Xinjian Yang, Chuhan Jiang, Youxiang Li, Zhongxue Wu
BACKGROUND: Intracranial fusiform aneurysm (IFA) is a relatively uncommon subgroup of aneurysms. There are few reports that focus on the hemodynamics of IFA. In this study, we compared the hemodynamics of the canine model of common carotid fusiform aneurysm and vertebrobasilar fusiform aneurysms in human patients. METHODS: Five male mongrel dogs were randomly chosen, and there unilateral common carotid artery (CCA) and external jugular vein were surgically exposed individually...
September 22, 2017: International Angiology: a Journal of the International Union of Angiology
https://www.readbyqxmd.com/read/28944812/spin-state-correlated-optical-properties-of-copper-ii-nitroxide-based-molecular-magnets
#2
Irina Yu Barskaya, Sergey L Veber, Elizaveta A Suturina, Peter S Sherin, Kseniya Yu Maryunina, Natalia A Artiukhova, Evgeny V Tretyakov, Renad Z Sagdeev, Victor I Ovcharenko, Nina P Gritsan, Matvey V Fedin
Molecular magnets based on copper(ii) ions and stable nitroxide radicals exhibit promising switchable behavior triggered by a number of external stimuli; however, their spin-state-correlated optical properties vital for photoinduced switching have not been profoundly investigated to date. Herein, the electronic absorption spectra of single crystals of three representatives of this unique family are studied experimentally and theoretically in the visible and near-IR regions. We established that the color of the complexes is mainly determined by optical properties of the nitroxide radicals, whereas the Cu(hfac)2 fragment contributes to the near-IR range with the intensity smaller by an order of magnitude...
September 25, 2017: Dalton Transactions: An International Journal of Inorganic Chemistry
https://www.readbyqxmd.com/read/28944731/the-fda-unapproved-drugs-initiative-an-observational-study-of-the-consequences-for-drug-prices-and-shortages-in-the-united-states
#3
Ravi Gupta, Sanket S Dhruva, Erin R Fox, Joseph S Ross
BACKGROUND: Hundreds of drug products are currently marketed in the United States without approval from the FDA. The 2006 Unapproved Drugs Initiative (UDI) requires manufacturers to remove these drug products from the market or obtain FDA approval by demonstrating evidence of safety and efficacy. Once the FDA acts against an unapproved drug, fewer manufacturers remain in the market, potentially enabling drug price increases and greater susceptibility to drug shortages. There is a need for systematic study of the UDI's effect on prices and shortages of all targeted drugs...
October 2017: Journal of Managed Care & Specialty Pharmacy
https://www.readbyqxmd.com/read/28944715/balance-training-enhances-motor-coordination-during-a-perturbed-side-step-cutting-task
#4
Anderson Souza Oliveira, Priscila de Brito Silva, Morten Enemark Lund, Dario Farina, Uwe Gustav Kersting
Study Design Controlled laboratory study. Background Balance training (BTR) may improve motor coordination, however little is known about the changes in motor coordination during unexpected perturbations to postural control following BTR. Objectives To study the effects of BTR on motor coordination and knee mechanics during perturbed side-step cutting maneuvers in healthy adults. Methods Twenty-six healthy men were randomly assigned to a training group (TG) or control (CG). Before BTR, subjects performed unperturbed, 90° side-step cutting maneuvers and one unexpected perturbed cut (10-cm translation of a moveable platform)...
September 23, 2017: Journal of Orthopaedic and Sports Physical Therapy
https://www.readbyqxmd.com/read/28944693/implementation-of-automatic-external-defibrillator-using-real-time-ventricular-fibrillation-detecting-algorithm-based-on-time-domain-analysis
#5
Ki Woong Seong, Sung Dae Na, Young Sik Park, Hee-Joon Park, Myoung Nam Kim, Jin-Ho Cho, Jyung Hyun Lee
The increase in mortality associated with arrhythmia is an inevitable problem of modern society such as westernized eating habits and an increase in stress due to industrialization, and the related social costs are increasing. In this regard, the supply of automatic external defibrillator (AED) used outside hospitals is increasing mainly in public institutions, and AED is a medical practice performed by non-medical personnel. Therefore, studies on arrhythmia detection algorithm to make accurate clinical judgment for proper use are increasing...
September 25, 2017: Computer Assisted Surgery (Abingdon, England)
https://www.readbyqxmd.com/read/28944620/intracoronary-snaring-of-the-retrograde-guidewire-how-to-overcome-extreme-takeoff-angles-in-chronic-total-occlusion-percutaneous-coronary-intervention
#6
Lorenzo Azzalini, Luciano Candilio, Mauro Carlino, Antonio Colombo
Extreme angulation of coronary artery takeoff represents a challenge for wiring and device advancement in percutaneous coronary intervention (PCI). This anatomic feature is particularly adverse in cases of chronic total occlusion (CTO) of the ostial-proximal segment of the target vessel. In this setting, the retrograde approach can help getting access to the occlusion. However, difficulties might arise at the critical step of wire externalization, due to the need to overcome the extreme ostial angle. Here, we describe a case of successful CTO PCI of the proximal circumflex artery, which presented an extreme angle at its takeoff...
September 25, 2017: Catheterization and Cardiovascular Interventions
https://www.readbyqxmd.com/read/28944559/harnessing-photochemical-shrinkage-in-direct-laser-writing-for-shape-morphing-of-polymer-sheets
#7
Anton A Bauhofer, Sebastian Krödel, Jan Rys, Osama R Bilal, Andrei Constantinescu, Chiara Daraio
Structures that change their shape in response to external stimuli unfold possibilities for more efficient and versatile production of 3D objects. Direct laser writing (DLW) is a technique based on two-photon polymerization that allows the fabrication of microstructures with complex 3D geometries. Here, it is shown that polymerization shrinkage in DLW can be utilized to create structures with locally controllable residual stresses that enable programmable, self-bending behavior. To demonstrate this concept, planar and 3D-structured sheets are preprogrammed to evolve into bio-inspired shapes (lotus flowers and shark skins)...
September 25, 2017: Advanced Materials
https://www.readbyqxmd.com/read/28944396/light-induced-piston-nanoengines-ultrafast-shuttling-of-a-styryl-dye-inside-cucurbit-7-uril
#8
Ekaterina Y Chernikova, Daria V Berdnikova, Yuri V Fedorov, Olga A Fedorova, François Maurel, Gediminas Jonusauskas
The combination of photoactive styryl(pyridinium) dyes and cucurbit[7]uril (CB[7]) in an integrated supramolecular system allowed us to design a novel high speed molecular machine based on the fully reversible shuttling motion of the dye inside the CB[7] host cavity. The driving force of this movement is the electrostatic potential change after the occurrence of intramolecular charge transfer in the excited state of the dye molecule that can be externally controlled by light. Steady-state and time-resolved optical spectroscopy as well as DFT calculations provided an unambiguous evidence for the ultrafast piston-like movement of the system between two states...
September 25, 2017: Physical Chemistry Chemical Physics: PCCP
https://www.readbyqxmd.com/read/28944386/nonexponential-kinetics-of-ion-pair-dissociation-in-electrofreezing-water
#9
Mohammad Alaghemandi, Volkmar Koller, Jason R Green
Temporally- or spatially-heterogeneous environments can participate in many kinetic processes, from chemical reactions and self-assembly to the forced dissociation of biomolecules. Here, we simulate the molecular dynamics of a model ion pair forced to dissociate in an explicit, aqueous solution. Triggering dissociation with an external electric field causes the surrounding water to electrofreeze and the ion pair population to decay nonexponentially. To further probe the role of the aqueous environment in the kinetics, we also simulate dissociation events under a purely mechanical force on the ion pair...
September 25, 2017: Physical Chemistry Chemical Physics: PCCP
https://www.readbyqxmd.com/read/28944328/contribution-of-intraoperative-neuromonitoring-to-the-identification-of-the-external-branch-of-superior-laryngeal-nerve
#10
Nurcihan Aygün, Mehmet Uludağ, Adnan İşgör
OBJECTIVE: We evaluated the contribution of intraoperative neuromonitoring to the visual and functional identification of the external branch of the superior laryngeal nerve. MATERIAL AND METHODS: The prospectively collected data of patients who underwent thyroid surgery with intraoperative neuromonitoring for external branch of the superior laryngeal nerve exploration were assessed retrospectively. The surface endotracheal tube-based Medtronic NIM3 intraoperative neuromonitoring device was used...
2017: Turk J Surg
https://www.readbyqxmd.com/read/28944308/titanium-dioxide-nanoparticle-ingestion-alters-nutrient-absorption-in-an-in-vitro-model-of-the-small-intestine
#11
Zhongyuan Guo, Nicole J Martucci, Fabiola Moreno-Olivas, Elad Tako, Gretchen J Mahler
Ingestion of titanium dioxide (TiO2) nanoparticles from products such as agricultural chemicals, processed food, and nutritional supplements is nearly unavoidable. The gastrointestinal tract serves as a critical interface between the body and the external environment, and is the site of essential nutrient absorption. The goal of this study was to examine the effects of ingesting the 30 nm TiO2 nanoparticles with an in vitro cell culture model of the small intestinal epithelium, and to determine how acute or chronic exposure to nano-TiO2 influences intestinal barrier function, reactive oxygen species generation, proinflammatory signaling, nutrient absorption (iron, zinc, fatty acids), and brush border membrane enzyme function (intestinal alkaline phosphatase)...
January 2017: NanoImpact
https://www.readbyqxmd.com/read/28944130/brain-computed-tomography-angiography-as-an-ancillary-test-in-the-confirmation-of-brain-death
#12
Homa Sadeghian, Mohammad Ali Raeisi, Parviz Dolati, Rouzbeh Motiei-Langroudi
Introduction Brain death (BD) is the irreversible termination of the functioning of the brain. The diagnosis should be first made by clinical criteria and confirmed by using paraclinical confirmatory techniques (ancillary tests). While conventional brain angiography remains the standard method of choice, computed tomography angiography (CTA) has emerged as an alternative method. In this study, we tried to evaluate the accuracy of CTA for the diagnosis of BD. Methods In this study, we included nine patients with a clinical diagnosis of BD, confirmed by electroencephalography (EEG)...
July 19, 2017: Curēus
https://www.readbyqxmd.com/read/28944055/understanding-the-links-between-resilience-and-type-2-diabetes-self-management-a-qualitative-study-in-south-australia
#13
A L Wilson, D McNaughton, S B Meyer, P R Ward
BACKGROUND: Research conducted by Ward, Muller, Tsourtos, et al. (Soc Sci Med 72(7):1140-1148, 2011) has led to the development of the psycho-social interactive model of resilience, which reveals the interaction between individual resilience factors (i.e. coping, confidence and self esteem) and external resilience environments (i.e. employment, supportive family environments and health promoting policies) in facilitating the development of resilience. This present study explored the utility of this model of resilience for understanding how people self-manage type-2 diabetes...
2017: Archives of Public Health, Archives Belges de Santé Publique
https://www.readbyqxmd.com/read/28943976/is-empiricism-empirically-false-lessons-from-early-nervous-systems
#14
Marcin Miłkowski
Recent work on skin-brain thesis (de Wiljes et al. 2015; Keijzer 2015; Keijzer et al. 2013) suggests the possibility of empirical evidence that empiricism is false. It implies that early animals need no traditional sensory receptors to be engaged in cognitive activity. The neural structure required to coordinate extensive sheets of contractile tissue for motility provides the starting point for a new multicellular organized form of sensing. Moving a body by muscle contraction provides the basis for a multicellular organization that is sensitive to external surface structure at the scale of the animal body...
2017: Biosemiotics
https://www.readbyqxmd.com/read/28943874/a-genome-wide-prediction-and-identification-of-intergenic-small-rnas-by-comparative-analysis-in-mesorhizobium-huakuii-7653r
#15
Xie Fuli, Zhao Wenlong, Wang Xiao, Zhang Jing, Hao Baohai, Zou Zhengzheng, Ma Bin-Guang, Li Youguo
In bacteria, small non-coding RNAs (sRNAs) are critical regulators of cellular adaptation to changes in metabolism, physiology, or the external environment. In the last decade, more than 2000 of sRNA families have been reported in the Rfam database and have been shown to exert various regulatory functions in bacterial transcription and translation. However, little is known about sRNAs and their functions in Mesorhizobium. Here, we predicted putative sRNAs in the intergenic regions (IGRs) of M. huakuii 7653R by genome-wide comparisons with four related Mesorhizobial strains...
2017: Frontiers in Microbiology
https://www.readbyqxmd.com/read/28943851/in-silico-analysis-of-small-rnas-suggest-roles-for-novel-and-conserved-mirnas-in-the-formation-of-epigenetic-memory-in-somatic-embryos-of-norway-spruce
#16
Igor A Yakovlev, Carl G Fossdal
Epigenetic memory in Norway spruce affects the timing of bud burst and bud set, vitally important adaptive traits for this long-lived forest species. Epigenetic memory is established in response to the temperature conditions during embryogenesis. Somatic embryogenesis at different epitype inducing (EpI) temperatures closely mimics the natural processes of epigenetic memory formation in seeds, giving rise to epigenetically different clonal plants in a reproducible and predictable manner, with respect to altered bud phenology...
2017: Frontiers in Physiology
https://www.readbyqxmd.com/read/28943809/an-audio-jack-based-electrochemical-impedance-spectroscopy-sensor-for-point-of-care-diagnostics
#17
Haowei Jiang, Alex Sun, A G Venkatesh, Drew A Hall
Portable and easy-to-use point-of-care (POC) diagnostic devices hold high promise for dramatically improving public health and wellness. In this paper, we present a mobile health (mHealth) immunoassay platform based on audio jack embedded devices, such as smartphones and laptops, that uses electrochemical impedance spectroscopy (EIS) to detect binding of target biomolecules. Compared to other biomolecular detection tools, this platform is intended to be used as a plug-and-play peripheral that reuses existing hardware in the mobile device and does not require an external battery, thereby improving upon its convenience and portability...
February 1, 2017: IEEE Sensors Journal
https://www.readbyqxmd.com/read/28943799/an-analytic-analysis-of-the-pion-decay-constant-in-three-flavoured-chiral-perturbation-theory
#18
B Ananthanarayan, Johan Bijnens, Shayan Ghosh
A representation of the two-loop contribution to the pion decay constant in SU(3) chiral perturbation theory is presented. The result is analytic up to the contribution of the three (different) mass sunset integrals, for which an expansion in their external momentum has been taken. We also give an analytic expression for the two-loop contribution to the pion mass based on a renormalized representation and in terms of the physical eta mass. We find an expansion of [Formula: see text] and [Formula: see text] in the strange-quark mass in the isospin limit, and we perform the matching of the chiral SU(2) and SU(3) low-energy constants...
2017: European Physical Journal. C, Particles and Fields
https://www.readbyqxmd.com/read/28943772/meat-tenderness-characteristics-of-ten-major-muscles-from-hanwoo-steers-according-to-quality-grades-of-carcasses
#19
Kyu-Won Lee, Young-Hwa Hwang, Seon-Tea Joo
The objective of this study was to determine the influence of quality grade (QG) on meat tenderness characteristics of ten major muscles from Hanwoo steers. A total of 25 Hanwoo carcasses (5 carcasses × 5 QGs) were selected. Intramuscular fat content, collagen content, sarcomere length, and Warner-Bratzler shear force (WBSF) of Longissimus thoracis (LT), Longissimus lumborum (LL), Psoas major (PM), Semisponals (SS), Triceps brachii (TB), Semimembranosus (SM), Gluteus medius (GM), Rectus Abdominis (RA), Superficialis flexor (SF), and Internal and external intercostal (IC) were determined...
2017: Korean Journal for Food Science of Animal Resources
https://www.readbyqxmd.com/read/28943706/theoretical-predictions-for-spatially-focused-heating-of-magnetic-nanoparticles-guided-by-magnetic-particle-imaging-field-gradients
#20
Rohan Dhavalikar, Carlos Rinaldi
Magnetic nanoparticles in alternating magnetic fields (AMFs) transfer some of the field's energy to their surroundings in the form of heat, a property that has attracted significant attention for use in cancer treatment through hyperthermia and in developing magnetic drug carriers that can be actuated to release their cargo externally using magnetic fields. To date, most work in this field has focused on the use of AMFs that actuate heat release by nanoparticles over large regions, without the ability to select specific nanoparticle-loaded regions for heating while leaving other nanoparticle-loaded regions unaffected...
December 1, 2016: Journal of Magnetism and Magnetic Materials
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