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https://www.readbyqxmd.com/read/28930974/procedure-and-key-optimization-strategies-for-an-automated-capillary-electrophoretic-based-immunoassay-method
#1
Gail M Nelson, Jenna M Guynn, Brian N Chorley
New technologies that utilize capillary-based immunoassays promise faster and more quantitative protein assessment compared to traditional immunoassays. However, similar to other antibody-based protein assays, optimization of capillary-based immunoassay parameters, such as protein concentration, antibody dilution, and exposure time is an important prerequisite to the generation of meaningful and reliable data. Measurements must fall within the linear range of the assay where changes in signal are directly proportional to changes in lysate concentration...
September 10, 2017: Journal of Visualized Experiments: JoVE
https://www.readbyqxmd.com/read/28930799/characterizing-the-interrelationships-of-prescription-opioid-and-benzodiazepine-drugs-with-worker-health-and-workplace-hazards
#2
Michele Kowalski-McGraw, Judith Green-McKenzie, Sudha P Pandalai, Paul A Schulte
OBJECTIVE: Prescription opioid and benzodiazepine drug use, which has risen significantly, can affect worker health. Exploration of the scientific literature assessed (1) interrelationships of such drug use, occupational risk factors, and illness and injury, and (2) occupational and personal risk factor combinations that can affect their use. METHODS: The scientific literature from 2000 to 2015 was searched to determine any interrelationships. RESULTS: Evidence for eight conceptual models emerged based on the search yield of 133 articles...
September 19, 2017: Journal of Occupational and Environmental Medicine
https://www.readbyqxmd.com/read/28929576/systolic-orthostatic-hypotension-is-related-to-lowered-cognitive-function-findings-from-the-maine-syracuse-longitudinal-study
#3
Rachael V Torres, Merrill F Elias, Georgina E Crichton, Gregory A Dore, Adam Davey
The aim of the present study was to examine the relationship between orthostatic changes in blood pressure (BP) and cognition, with consideration given to cardiovascular risk factors and lifestyle variables. The cross-sectional analysis included 961 community-dwelling participants of the Maine-Syracuse Longitudinal Study, for whom BP clinic measures (five sitting, five recumbent, and five standing) were obtained. Eighteen percent of participants had orthostatic hypotension (fall in systolic BP ≥20 mm Hg or diastolic BP ≥10 mm Hg upon standing) and 6% had orthostatic hypertension (rise in systolic BP ≥20 mm Hg)...
September 19, 2017: Journal of Clinical Hypertension
https://www.readbyqxmd.com/read/28929352/the-relative-sensitivity-of-freshwater-species-to-antimony-iii-implications-for-water-quality-guidelines-and-ecological-risk-assessments
#4
Maximilian Obinna Obiakor, Matthew Tighe, Zhen Wang, Chigozie Damian Ezeonyejiaku, Lily Pereg, Susan C Wilson
Antimony (Sb) is a pollutant in many jurisdictions, yet its threat to aquatic biota is unclear. Water quality guidelines (WQGs) for Sb are not well established and large uncertainty factors are commonly applied in derivation. We constructed freshwater species sensitivity distributions (SSDs) for Sb(III) using available acute toxicity data sourced from temperate and tropical regional studies. A tiered ecological risk assessment (ERA) approach using risk quotients (RQs) was applied for characterisation of risks presented by Sb(III) concentrations measured in the freshwater environment...
September 19, 2017: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/28929161/synthesis-and-photophysical-properties-of-a-bichromophoric-system-hosting-a-disaccharide-spacer
#5
T Papalia, A Barattucci, S Campagna, F Puntoriero, T Salerno, P Bonaccorsi
The synthesis of an efficient energy donor-acceptor system is reported, together with its photophysical properties. The bichromophoric species has been conceived to show potentialities for biological applications since a biocompatible disaccharide spacer, constituted of d-galactose and d-glucose derivatives, was used in compound 12 to connect two BODIPY units with different absorption/emission properties. The luminescence spectrum in acetonitrile of 12 shows an intense fluorescence band with a maximum at about 770 nm that is almost identical to that of the lowest-energy BODIPY, regardless of the excitation wavelength used...
September 20, 2017: Organic & Biomolecular Chemistry
https://www.readbyqxmd.com/read/28929061/drug-induced-sleep-endoscopy-as-a-selection-tool-for-surgical-management-of-obstructive-sleep-apnoea-syndrome-our-personal-experience
#6
M B Bharathi, J Rajendra Prasad, K Satish
The role of Drug-induced sleep endoscopy as a selection tool for surgical management of obstructive sleep apnoea syndrome. SOURCE OF DATA: Polysomnography proved OSA patients, who are planned for surgery in dept. of ENT AND HEAD& NECK, JSS Hospital, Mysore. STUDY DESIGN: A prospective clinical study. METHOD: 30 Polysomnography proved OSA patients, age between 20 and 60 years have been selected for Drug Induced Sleep Endoscopy (DISE) after taking informed consent for proposed surgery...
September 2017: Indian Journal of Otolaryngology and Head and Neck Surgery
https://www.readbyqxmd.com/read/28928958/exploring-vietnamese-co-authorship-patterns-in-social-sciences-with-basic-network-measures-of-2008-2017-scopus-data
#7
Tung Manh Ho, Ha Viet Nguyen, Thu-Trang Vuong, Quang-Minh Dam, Hiep-Hung Pham, Quan-Hoang Vuong
Background: Collaboration is a common occurrence among Vietnamese scientists; however, insights into Vietnamese scientific collaborations have been scarce. On the other hand, the application of social network analysis in studying science collaboration has gained much attention all over the world. The technique could be employed to explore Vietnam's scientific community. Methods: This paper employs network theory to explore characteristics of a network of 412 Vietnamese social scientists whose papers can be found indexed in the Scopus database...
2017: F1000Research
https://www.readbyqxmd.com/read/28928653/age-related-decline-in-anticipatory-motor-planning-and-its-relation-to-cognitive-and-motor-skill-proficiency
#8
Tino Stöckel, Kathrin Wunsch, Charmayne M L Hughes
Anticipatory motor planning abilities mature as children grow older, develop throughout childhood and are likely to be stable till the late sixties. In the seventh decade of life, motor planning performance dramatically declines, with anticipatory motor planning abilities falling to levels of those exhibited by children. At present, the processes enabling successful anticipatory motor planning in general, as do the cognitive processes mediating these age-related changes, remain elusive. Thus, the aim of the present study was (a) to identify cognitive and motor functions that are most affected by normal aging and (b) to elucidate key (cognitive and motor) factors that are critical for successful motor planning performance in young (n = 40, mean age = 23...
2017: Frontiers in Aging Neuroscience
https://www.readbyqxmd.com/read/28928606/quantification-of-ventricular-unloading-by-3d-echocardiography-in-single-ventricle-of-left-ventricular-morphology-following-superior-cavo-pulmonary-anastomosis-and-fontan-completion-a-feasibility-study
#9
Deepa Sasikumar, Bijulal Sasidharan, Baiju S Dharan, Arun Gopalakrishnan, Kavasseri M Krishnamoorthy, Sivasubramanian Sivasankaran
BACKGROUND: Three-dimensional echocardiography. (3DE) is comparable to cardiac magnetic resonance imaging for estimating ventricular volume in congenital heart diseases. However, there are limited data on estimation of ventricular volumes by 3DE in univentricular heart and change in ventricular volumes after surgical creation of cavopulmonary connection. We sought to quantify the unloading of the single ventricle of left ventricular. (LV) morphology by 3DE after superior cavopulmonary anastomosis...
September 2017: Annals of Pediatric Cardiology
https://www.readbyqxmd.com/read/28928031/effect-of-curriculum-changes-on-student-performance-during-general-surgical-clerkship
#10
Elizabeth A Hagan, Bernard M Jaffe
INTRODUCTION: Good clinical knowledge of anatomy, taught in medical school, is necessary for practicing physicians. It is a key feature of performance on the United States Medical Licensing Examination Step 1 score. Student performance on anatomy is also an early indicator of overall medical student performance. Unfortunately, curricular time provided for the teaching of anatomy has declined significantly over the last 30 years, leading to growing concerns that the anatomical knowledge of new medical graduates may not be adequate...
September 15, 2017: Journal of Surgical Education
https://www.readbyqxmd.com/read/28927881/four-year-outcomes-of-midcarpal-hemiarthroplasty-for-wrist-arthritis
#11
Marie Anneberg, Greg Packer, Joseph J Crisco, Scott Wolfe
PURPOSE: The purpose of this study was to review the average 4-year outcomes of a cohort of patients with wrist arthritis, treated by a single surgeon with a novel prosthetic hemiarthroplasty of the midcarpal joint. We hypothesized that midcarpal hemiarthroplasty would improve range of motion and grip strength of patients with wrist arthritis, with a complication profile comparable with that of alternative solutions for wrist arthritis. METHODS: We reviewed a series of 20 patients treated with a midcarpal hemiarthroplasty at an average of 4 years following surgery...
September 16, 2017: Journal of Hand Surgery
https://www.readbyqxmd.com/read/28927514/prevalence-of-depression-and-associated-factors-in-non-institutionalized-older-adults-with-a-previous-history-of-falling
#12
Begoña Pellicer-García, Isabel Antón-Solanas, Sergio Moreno-González, Enrique Castro-Sánchez, Raúl Juárez-Vela
The purpose of this paper was to estimate the prevalence of depression and associated factors in people aged 65 or older with a history of falling in the last 12months. A cross-sectional descriptive study was performed involving a random sample of 213 participants from two social centers for older adults in the city of Zaragoza (Spain). The mean age of the participants was 77.3years (SD±7.0). Our findings reveal a prevalence of depression of 28.2% in the study sample, with older adults who were at a high risk of falling being more susceptible to developing depression...
October 2017: Archives of Psychiatric Nursing
https://www.readbyqxmd.com/read/28927422/proximity-to-vector-breeding-site-and-risk-of-plasmodium-vivax-infection-a-prospective-cohort-study-in-rural-ethiopia
#13
Alexander Nissen, Jackie Cook, Eskindir Loha, Bernt Lindtjørn
BACKGROUND: Despite falling incidence and mortality since the turn of the century, malaria remains an important global health challenge. In the future fight against malaria, greater emphasis will have to be placed on understanding and addressing malaria caused by the Plasmodium vivax parasite. Unfortunately, due to years of neglect and underfunding, there are currently many gaps in knowledge of P. vivax malaria. The aims of the present study were to explore the association between distance to vector breeding site and P...
September 19, 2017: Malaria Journal
https://www.readbyqxmd.com/read/28927372/potentially-inappropriate-medication-use-in-nursing-homes-an-observational-study-using-the-norgep-nh-criteria
#14
Gunhild Nyborg, Mette Brekke, Jørund Straand, Svein Gjelstad, Maria Romøren
BACKGROUND: Frail residents in the nursing home sector call for extra care in prescribing. The Norwegian General Practice Nursing Home (NORGEP-NH) list of 34 explicit criteria for potentially inappropriate medication use in nursing homes was developed explicitly for this population. The aim of this study was to employ the NORGEP-NH Criteria to study the extent of potentially inappropriate medication use among nursing home residents and explore possible associated factors. METHODS: Cross-sectional observational pharmacoepidemiological study from residents in nursing homes in the county of Vestfold, Norway...
September 19, 2017: BMC Geriatrics
https://www.readbyqxmd.com/read/28927304/initial-outcomes-of-a-participatory-based-competency-building-approach-to-increasing-physical-education-teachers-physical-activity-promotion-and-students-physical-activity-a-pilot-study
#15
R Glenn Weaver, Collin A Webster, Michael W Beets, Keith Brazendale, Jessica Chandler, Lauren Schisler, Mazen Aziz
This study examined the initial effects of a participatory-based, competency-/skill-building professional development workshop for physical education (PE) teachers on the use of physical activity (PA) promotion practices (e.g., eliminating lines, small-sided games) and students' moderate-to-vigorous physical activity (MVPA). A total of 823 students (52.8% boys) wore accelerometers at baseline (fall 2015) and outcome (spring 2016) on PE and non-PE days. The System for Observing Fitness Instruction Time+ measured changes in PA promotion practices...
September 1, 2017: Health Education & Behavior: the Official Publication of the Society for Public Health Education
https://www.readbyqxmd.com/read/28927235/the-effect-of-complex-interventions-on-supporting-self-care-among-community-dwelling-older-adults-a-systematic-review-and-meta-analysis
#16
Kwan Ching Wong, Frances Kam Yuet Wong, W F Yeung, Katherine Chang
Background: self-care is critical to enable community-dwelling older adults to live independently. Complex interventions have emerged as a strategy to support self-care, but their effectiveness is unknown. Our objective was to review systematically their effectiveness on both positive (increased scores in self-rated health, Activities of Daily Living, Instrumental Activities of Daily Living, quality of life) and negative aspects (increased incidence of falls, fear of falling, hospital and nursing home admission, increased depression score), and to determine which intervention components explain the observed effects...
September 13, 2017: Age and Ageing
https://www.readbyqxmd.com/read/28927207/surgical-approaches-to-the-temporal-horn-an-anatomic-analysis-of-white-matter-tract-interruption
#17
Paulo A S Kadri, Jean G de Oliveira, Niklaus Krayenbühl, Ugur Türe, Evandro P L de Oliveira, Ossama Al-Mefty, Guilherme C Ribas
BACKGROUND: Surgical access to the temporal horn is necessary to treat tumors and vascular lesions, but is used mainly in patients with mediobasal temporal epilepsy. The surgical approaches to this cavity fall into 3 primary categories: lateral, inferior, and transsylvian. The current neurosurgical literature has underestimated the interruption of involved fiber bundles and the correlated clinical manifestations. OBJECTIVE: To delineate the interruption of fiber bundles during the different approaches to the temporal horn...
April 1, 2017: Operative Neurosurgery (Hagerstown, Md.)
https://www.readbyqxmd.com/read/28926594/history-of-nonnative-monk-parakeets-in-mexico
#18
Elizabeth A Hobson, Grace Smith-Vidaurre, Alejandro Salinas-Melgoza
Nonnative Monk Parakeets have been reported in increasing numbers across many cities in Mexico, and were formally classified as an invasive species in Mexico in late 2016. However, there has not been a large-scale attempt to determine how international pet trade and national and international governmental regulations have played a part in colonization, and when the species appeared in different areas. We describe the changes in regulations that led the international pet trade market to shift to Mexico, then used international trade data to determine how many parakeets were commercially imported each year and where those individuals originated...
2017: PloS One
https://www.readbyqxmd.com/read/28926476/the-effects-of-brief-swaying-on-postural-control
#19
Sara Pagé, Maxime Maheu, Simon P Landry, François Champoux
Postural control can be improved with balance training. However, the nature and duration of the training required to enhance posture remains unclear. We studied the effects of 5 min of a self-initiated balance exercise along a single axis on postural control in healthy individuals. Postural control was measured before and after a 5-min period where members of the experimental group were asked to lean their entire body forward and backward and members of the control group were asked to remain seated. A significant improvement for sway velocity, a postural control variable significantly associated with an increased risk of falls, was found in the experimental group following the body sway exercise...
September 18, 2017: Neuroreport
https://www.readbyqxmd.com/read/28926347/laryngohyoid-fractures-in-fatal-nonhomicidal-falls-from-a-height
#20
Hüseyin Eş, Muhammed Feyzi Şahin, Erdinç Özdemir
In cases of fall from a height, the presence of laryngohyoid fracture or bleeding at autopsy constitutes a suspicion of strangulation before trauma in these types of cases. This study has aimed to investigate the incidence of laryngohyoid fractures in nonhomicidal fall from height cases, and their relationship with age, sex, height of fall, body mass index, and other injuries.A total of 170 cases proven to be nonhomicidal falls from height with certain witnesses and evidences in 4683 autopsy cases in 2013 were included in this study...
September 16, 2017: American Journal of Forensic Medicine and Pathology
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