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Vestibular System

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https://www.readbyqxmd.com/read/29778132/cervical-vestibular-evoked-myogenic-potentials-cvemps-evoked-by-air-conducted-stimuli-in-patients-with-functional-neck-dissection
#1
Hasan Demirhan, Bahtiyar Hamit, Özgür Yiğit
OBJECTIVE: Cervical vestibular-evoked myogenic potentials (cVEMPs) are short-latency vestibulocollic reflexes. The damage on any point of the vestibulocollic reflex pathway could affect the cVEMPs. Whether neck dissection has an effect on the sacculocollic pathway, and consequently on cVEMPs, remains unexplored. The aim of this study was to evaluate the cVEMP findings in patients with functional neck dissection without vestibular symptoms. PATIENTS AND METHODS: This cross-sectional study design, 20 patients who had undergone unilateral neck dissection with sparing of the accessory nerve, SCM and internal jugular vein, were included...
June 2018: Journal of the National Medical Association
https://www.readbyqxmd.com/read/29775147/intraoperative-cochlear-nerve-mapping-with-the-mobile-cochlear-nerve-compound-action-potential-tracer-in-vestibular-schwannoma-surgery
#2
Nobuyuki Watanabe, Takuya Ishii, Kazuhiko Fujitsu, Shogo Kaku, Teruo Ichikawa, Kosuke Miyahara, Tomu Okada, Shin Tanino, Yasuhiro Uriu, Yuichi Murayama
OBJECTIVE The authors describe the usefulness and limitations of the cochlear nerve compound action potential (CNAP) mobile tracer (MCT) that they developed to aid in cochlear nerve mapping during vestibular schwannoma surgery (VSS) for hearing preservation. METHODS This MCT device requires no more than 2 seconds for stable placement on the nerve to obtain the CNAP and thus is able to trace the cochlear nerve instantaneously. Simultaneous bipolar and monopolar recording is possible. The authors present the outcomes of 18 consecutive patients who underwent preoperative useful hearing (defined as class I or II of the Gardner-Robertson classification system) and underwent hearing-preservation VSS with the use of the MCT...
May 18, 2018: Journal of Neurosurgery
https://www.readbyqxmd.com/read/29768682/vestibulo-cortical-hemispheric-dominance-the-link-between-anxiety-and-the-vestibular-system
#3
Nadja F Bednarczuk, Marta Casanovas Ortega, Anne-Sophie Fluri, Qadeer Arshad
Vestibular processing and anxiety networks are functionally intertwined, as demonstrated by reports of reciprocal influences upon each other. Yet whether there is an underlying link between these two systems remains unknown Previous findings have highlighted the involvement of hemispheric lateralisation in processing of both anxiety and vestibular signals. Accordingly, we explored the interaction between vestibular cortical processing and anxiety by assessing the relationship between anxiety levels and the degree of hemispheric lateralisation of vestibulo-cortical processing in 64 right-handed, healthy individuals...
May 16, 2018: European Journal of Neuroscience
https://www.readbyqxmd.com/read/29764780/what-is-the-required-frequency-of-mri-scanning-in-the-wait-and-scan-management
#4
Thomas Somers, Romain Kania, Jerome Waterval, Tony Van Havenbergh
The wait and scan policy is being increasingly used as the first measure after the diagnosis of a vestibular schwannoma (VS) using magnetic resonance imaging (MRI). As part of the European Academy of Otology and Neuro-Otology (EAONO) position statement on VS, the frequency of imaging has been studied in the literature. Among 163 studies, 29 fulfilled the inclusion criteria and were scored using the Grading of Recommendations, Assessment, Development, and Evaluation system. Because tumor growth rate during the first 5 years of follow-up is predictive of further growth during the upcoming years, a protocol for wait and scan is useful for centers dealing with this condition...
April 2018: Journal of International Advanced Otology
https://www.readbyqxmd.com/read/29764619/effects-of-unexpected-visual-motion-on-postural-sway-and-motion-sickness
#5
Mark Dennison, Michael D'Zmura
Motion sickness is thought to occur when the brain's assumptions about incoming sensory information do not match the actual signals received. These signals must involve the vestibular system for motion sickness to occur. In this paper, we describe an experiment in which subjects experienced unexpected visual motions, or perturbations, as they navigated a virtual environment (VE) while standing and wearing a head mounted display (HMD) or while viewing a monitor. We found that postural instability, as measured by a balance board, increased with time only when perturbations were present...
September 2018: Applied Ergonomics
https://www.readbyqxmd.com/read/29761349/intracochlear-administration-of-steroids-with-a-catheter-during-human-cochlear-implantation-a-safety-and-feasibility-study
#6
Nils K Prenzler, Rolf Salcher, Max Timm, Lutz Gaertner, Thomas Lenarz, Athanasia Warnecke
Suppression of foreign body reaction, improvement of electrode-nerve interaction, and preservation of residual hearing are essential research topics in cochlear implantation. Intracochlear pharmaco- or cell-based therapies can open new horizons in this field. Local drug delivery strategies are desirable as higher local concentrations of agents can be realized and side effects can be minimized compared to systemic administrations. When administered locally at accessible, basal parts of the cochlea, drugs reach apical regions later and in much lower concentrations due to poor diffusion patterns in cochlear fluids...
May 14, 2018: Drug Delivery and Translational Research
https://www.readbyqxmd.com/read/29758728/amphibian-sacculus-and-the-forced-kuramoto-model-with-intrinsic-noise-and-frequency-dispersion
#7
Seung Ji, Dolores Bozovic, Robijn Bruinsma
The amphibian sacculus (AS) is an end organ that specializes in the detection of low-frequency auditory and vestibular signals. In this paper, we propose a model for the AS in the form of an array of phase oscillators with long-range coupling, subject to a steady load that suppresses spontaneous oscillations. The array is exposed to significant levels of frequency dispersion and intrinsic noise. We show that such an array can be a sensitive and robust subthreshold detector of low-frequency stimuli, though without significant frequency selectivity...
April 2018: Physical Review. E
https://www.readbyqxmd.com/read/29757553/-the-manifestation-of-videonystamography-in-the-patients-with-posterior-circulation-ischemia-vertigo
#8
Hao Wei Wang, Ying Guo, Jing Zhou, Hui Fang Zhou
Objective: To investigate the changes of vedionystamography(VNG)in patients with posterior circulation ischemia vertigo(PCIV). Method: Fifty patients who complained of vertigo and imbalance with PCI were selected as experimental group for testing of visual nystamography(VNG).Thirty normal subjects were chosen as control group.The result was analyzed. Result: The results of VNG in PCIV group and the control group were compared.The abnormal ratio were as follows:(4%,0; P >0.05)for Spontaneous nystagmus,(68%,10%; P <0...
January 20, 2018: Journal of Clinical Otorhinolaryngology, Head, and Neck Surgery
https://www.readbyqxmd.com/read/29757361/effects-of-rhinoplasty-on-labyrinthine-function
#9
Ahmet Mahmut Tekin, Erkan Soylu, Handan Turan Dizdar, Fahrettin Yilmaz, Yildirim Ahmet Bayazit
Background: Rhinoplasty is a common surgical procedure that is requested and accepted by patients for cosmetic and functional reasons. Osteotomies are performed on nasal bone, maxillary crest, or vomer to fix the deviations of the nasal dorsum or septum. During the percussion of the osteotomes with the surgical mallet, the vibration energy diffuses to the cranium. Auditory and vestibular systems may be affected by these vibrations. Objectives: To assess the effects of rhinoplasty, in which osteotomies were performed using a hammer, on the audiovestibular system...
May 11, 2018: Aesthetic Surgery Journal
https://www.readbyqxmd.com/read/29755404/cognitive-rehabilitation-in-bilateral-vestibular-patients-a-computational-perspective
#10
Andrew W Ellis, Corina G Schöne, Dominique Vibert, Marco D Caversaccio, Fred W Mast
There is evidence that vestibular sensory processing affects, and is affected by, higher cognitive processes. This is highly relevant from a clinical perspective, where there is evidence for cognitive impairments in patients with peripheral vestibular deficits. The vestibular system performs complex probabilistic computations, and we claim that understanding these is important for investigating interactions between vestibular processing and cognition. Furthermore, this will aid our understanding of patients' self-motion perception and will provide useful information for clinical interventions...
2018: Frontiers in Neurology
https://www.readbyqxmd.com/read/29754531/the-role-of-subconcussive-impacts-on-sway-velocities-in-division-i-men-s-lacrosse-players
#11
Theresa L Miyashita, Eleni Diakogeorgiou, Kaitlyn Marrie
Head impacts resulting in a concussion negatively affect the vestibular system, but little is known about the effect of subconcussive impacts on this system. This study's objective was to determine if subconcussive head impacts sustained over one competitive lacrosse season, effect sway velocity. Healthy Division I male lacrosse players (n = 33; aged 19.52 ± 1.20 years) wore instrumented helmets to track head impact exposures. At the beginning and end of the season the players completed an instrumented Balance Error Scoring System assessment to assess sway velocity...
May 12, 2018: Sports Biomechanics
https://www.readbyqxmd.com/read/29754270/heterozygous-missense-variants-of-lmx1a-lead-to-nonsyndromic-hearing-impairment-and-vestibular-dysfunction
#12
Mieke Wesdorp, Pia A M de Koning Gans, Margit Schraders, Jaap Oostrik, Martijn A Huynen, Hanka Venselaar, Andy J Beynon, Judith van Gaalen, Vitória Piai, Nicol Voermans, Michelle M van Rossum, Bas P Hartel, Stefan H Lelieveld, Laurens Wiel, Berit Verbist, Liselotte J Rotteveel, Marieke F van Dooren, Peter Lichtner, Henricus P M Kunst, Ilse Feenstra, Ronald J C Admiraal, Helger G Yntema, Lies H Hoefsloot, Ronald J E Pennings, Hannie Kremer
Unraveling the causes and pathomechanisms of progressive disorders is essential for the development of therapeutic strategies. Here, we identified heterozygous pathogenic missense variants of LMX1A in two families of Dutch origin with progressive nonsyndromic hearing impairment (HI), using whole exome sequencing. One variant, c.721G > C (p.Val241Leu), occurred de novo and is predicted to affect the homeodomain of LMX1A, which is essential for DNA binding. The second variant, c.290G > C (p.Cys97Ser), predicted to affect a zinc-binding residue of the second LIM domain that is involved in protein-protein interactions...
May 12, 2018: Human Genetics
https://www.readbyqxmd.com/read/29750195/utilizing-sensory-prediction-errors-for-movement-intention-decoding-a-new-methodology
#13
Gowrishankar Ganesh, Keigo Nakamura, Supat Saetia, Alejandra Mejia Tobar, Eiichi Yoshida, Hideyuki Ando, Natsue Yoshimura, Yasuharu Koike
We propose a new methodology for decoding movement intentions of humans. This methodology is motivated by the well-documented ability of the brain to predict sensory outcomes of self-generated and imagined actions using so-called forward models. We propose to subliminally stimulate the sensory modality corresponding to a user's intended movement, and decode a user's movement intention from his electroencephalography (EEG), by decoding for prediction errors-whether the sensory prediction corresponding to a user's intended movement matches the subliminal sensory stimulation we induce...
May 2018: Science Advances
https://www.readbyqxmd.com/read/29747963/the-possible-effect-of-human-menopausal-gonadotropin-on-the-audio-vestibular-system
#14
Montaser Abdel-Salam, Osama G Abdel-Naby Awad, Mohamed El-Badry, Ahmed Ibrahim, Mahmoud Hosny Ibrahiem
OBJECTIVE: Human menopausal gonadotropin (HMG) is one of the commonest drugs used for ovarian stimulation with no reports on the audio-vestibular system. This study aims to examine HMG on the hearing profile of patients planning intracytoplasmic sperm injection (ICSI). METHODS: This prospective study was conducted from June 2016 to June 2017 in a tertiary referral hospital. The audio-vestibular system of a total of 30 patients was evaluated using pure tone audiometry, distortion product otoacoustic emissions (DPOAEs in the form of a DP-gram) and Vestibular-evoked myogenic potential (VEMP) immediately before therapy and at the day 10 after therapy...
May 7, 2018: Auris, Nasus, Larynx
https://www.readbyqxmd.com/read/29745800/interaction-between-graviception-and-carotid-baroreflex-function-in-humans-during-parabolic-flight-induced-microgravity
#15
Shigehiko Ogoh, Michaël Marais, Romain Lericollais, Pierre Denise, Peter B Raven, Hervé Normand
The aim of the present study was to assess carotid baroreflex (CBR) during acute changes in otolithic activity in humans. To address this question, we designed a set of experiments to identify the modulatory effects of microgravity on CBR function at a tilt angle of -2{degree sign}, which was identified to minimize changes in central blood volume during parabolic flight. During parabolic flight at 0g and 1g, CBR function curves were modelled from the heart rate (HR) and mean arterial pressure (MAP) responses to rapid pulse trains of neck pressure (NP) and neck suction (NS) ranging from +40 to -80 Torr; CBR control of HR (carotid-HR) and MAP (carotid-MAP) baroreflex function curves, respectively...
May 10, 2018: Journal of Applied Physiology
https://www.readbyqxmd.com/read/29745627/neurophysiological-and-clinical-effects-of-blinfolded-balance-training-bbt-in-parkinson-s-disease-patients-a-preliminary-study
#16
Sonia Bonnì, Viviana Ponzo, Marco Tramontano, Alex Martino Cinnera, Carlo Caltagirone, Giacomo Koch, Antonella Peppe
BACKGROUND: Recent evidence support the hypothesis that rehabilitative strategies based on sensorimotor stimulation in the neurorehabilitation of Parkinson's Disease (PD) may be useful to improve gait in PD patients. AIM: We supposed that sensorimotor stimulation produce modulation of Anticipatory Postural Adjustments (APAs) arising from the supplementary motor area (SMA). We aimed to investigate the clinical and neurophysiological effects of a blindfolded balance training (BBT)...
May 9, 2018: European Journal of Physical and Rehabilitation Medicine
https://www.readbyqxmd.com/read/29741128/vestibulotoxicity-strategies-for-clinical-diagnosis-and-rehabilitation
#17
Jaynee A Handelsman
OBJECTIVE: The purpose of this article is to discuss the most commonly prescribed vestibulotoxic medications and their impact on the vestibular system, to describe the clinical features of vestibular ototoxicity including symptoms reported by patients, and to describe assessment tools that may be used in a monitoring programme, including the functional impact of vestibular loss. Recently published data from a cohort of patients exposed to systemic aminoglycosides (AGS) are summarised, which highlight the importance of monitoring...
May 9, 2018: International Journal of Audiology
https://www.readbyqxmd.com/read/29736101/comparative-study-of-two-systems-for-the-assessment-of-static-balance-in-veterans-with-mild-traumatic-brain-injury
#18
Azadeh Leland, Kamran Tavakol, Joel Scholten, Simin Bakhshi, Kaveh Kelarestaghi
Background: Traditionally, the diagnosis of postural instability relies on the clinical examination of static balance. In recent years, computerized technologies have provided a new approach for the accurate detection of positional changes during functional balance. Aim: The aim of this study was to investigate the similarities and differences between two electronic systems, NeuroCom and BioSensics , and their application in the clinical assessment of impaired balance in American veterans...
April 2018: Medical Archives
https://www.readbyqxmd.com/read/29734006/disentangling-the-visual-motor-and-representational-effects-of-vestibular-input
#19
Naotoshi Abekawa, Elisa R Ferrè, Maria Gallagher, Hiroaki Gomi, Patrick Haggard
The body midline provides a basic reference for egocentric representation of external space. Clinical observations have suggested that vestibular information underpins egocentric representations. Here we aimed to clarify whether and how vestibular inputs contribute to egocentric representation in healthy volunteers. In a psychophysical task, participants were asked to judge whether visual stimuli were located to the left or to the right of their body midline. Artificial vestibular stimulation was applied to stimulate the vestibular organs...
April 12, 2018: Cortex; a Journal Devoted to the Study of the Nervous System and Behavior
https://www.readbyqxmd.com/read/29728166/long-term-evaluation-of-the-effect-of-middle-ear-effusion-on-the-vestibular-system-in-children
#20
Katarzyna Pazdro-Zastawny, Lucyna Pośpiech, Tomasz Zatoński
BACKGROUND: Otitis media with effusion (OME) is one of the most common clinical conditions in childhood. Fluid accumulation in the middle ear may impact inner ear. OBJECTIVES: The purpose of this random sample cohort study was to investigate whether the past history of middle ear effusion has a long-term negative impact on the vestibular system in children. MATERIAL AND METHODS: The study was carried out on 22 children aged 7-15 years who had undergone drainage of the middle ear 5 years before evaluation...
June 2018: International Journal of Pediatric Otorhinolaryngology
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