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https://www.readbyqxmd.com/read/28722605/characterizing-reactivity-to-onchocerca-volvulus-antigens-in-multiplex-bead-assays
#1
Karla R Feeser, Vitaliano Cama, Jeffrey W Priest, Elizabeth A Thiele, Ryan E Wiegand, Thomson Lakwo, Sendeaw M Feleke, Paul T Cantey
Multiplex bead assays (MBAs) may provide a powerful integrated tool for monitoring, evaluation, and post-elimination surveillance of onchocerciasis and co-endemic diseases; however, the specificity and sensitivity of Onchocerca volvulus antigens have not been characterized within this context. An MBA was developed to evaluate three antigens (OV-16, OV-17, and OV-33) for onchocerciasis. Receiver operating characteristics (ROC) analyses were used to characterize antigen performance using a panel of 610 specimens: 109 O...
July 3, 2017: American Journal of Tropical Medicine and Hygiene
https://www.readbyqxmd.com/read/28717914/association-of-elevated-pre-operative-hemoglobin-a1c-and-post-operative-complications-in-non-diabetic-patients-a-systematic-review
#2
REVIEW
Negar Karimian, Petru Niculiseanu, Alexandre Amar-Zifkin, Francesco Carli, Liane S Feldman
IMPORTANCE: Pre-operative hyperglycemia is associated with post-operative adverse outcomes in diabetic and non-diabetic patients. Current pre-operative screening includes random plasma glucose, yet plasma glycated hemoglobin (HbA1c) is a better measure of long-term glycemic control. It is not clear whether pre-operative HbA1c can identify non-diabetic patients at risk of post-operative complications. OBJECTIVE: The systematic review summarizes the evidence pertaining to the association of suboptimal pre-operative HbA1c on post-operative outcomes in adult surgical patients with no history of diabetes mellitus...
July 17, 2017: World Journal of Surgery
https://www.readbyqxmd.com/read/28717869/transoral-endoscopic-thyroidectomy-vestibular-approach-toetva-indications-techniques-and-results
#3
Angkoon Anuwong, Thanyawat Sasanakietkul, Pornpeera Jitpratoom, Khwannara Ketwong, Hoon Yub Kim, Gianlorenzo Dionigi, Jeremy D Richmon
INTRODUCTION: The Transoral Neck Surgery (TONS) Study Group was established at the 1st International Thyroid NOTES Conference in February 2016 with the intention of standardizing and refining thyroid NOTES techniques, including both transoral endoscopic and robotic thyroidectomy approaches. Herein, the authors report the modification of indications, preparation, and step-by-step explanations for operative techniques, as well as results and postoperative care for transoral endoscopic thyroidectomy vestibular approach (TOETVA)...
July 17, 2017: Surgical Endoscopy
https://www.readbyqxmd.com/read/28717291/risk-factors-for-post-operative-infection-following-single-piece-osteotomy
#4
P U Abdul Wahab, P Senthil Nathan, M Madhulaxmi, M R Muthusekhar, Soh Chen Loong, Rajendra Prabhu Abhinav
OBJECTIVE: The aim of this retrospective study was to identify the significant risk factors that contribute towards postoperative infection in patients recovering from orthognathic surgery. METHODS: Retrospective records of 522 patients who underwent orthognathic surgery over 9 year period were evaluated for postoperative infection within 3 months of surgery and after 3 months of surgery. The variables of interest included age, gender, habits like smoking and alcohol consumption and incidence of postoperative infection...
September 2017: Journal of Maxillofacial and Oral Surgery
https://www.readbyqxmd.com/read/28714488/nasal-carriage-rate-of-methicillin-resistant-staphylococcus-aureus-among-health-care-workers-at-a-tertiary-care-hospital-in-kathmandu-nepal
#5
S Khatri, N D Pant, R Bhandari, K L Shrestha, C D Shrestha, N Adhikari, A Poudel
BACKGROUND: Methicillin-resistant Staphylococcus aureus is one of the most common causes of nosocomial infections. Due to its multidrug resistant nature; infections due to Methicillin-resistant Staphylococcus aureus are often very difficult to treat. Colonized health care workers are the important sources of Methicillin-resistant Staphylococcus aureus. The objectives of this study were to determine the nasal carriage rate of Methicillin-resistant Staphylococcus aureus among health care workers at Kathmandu Medical College and Teaching Hospital, Nepal and to assess their antimicrobial susceptibility patterns...
January 2017: Journal of Nepal Health Research Council
https://www.readbyqxmd.com/read/28712889/the-adjustable-transobturator-male-system-in-stress-urinary-incontinence-after-transurethral-resection-of-the-prostate
#6
Alexander Friedl, Jenifer Schneeweiss, Kathrin Stangl, Sandra Mühlstädt, Roman Zachoval, Stephan Hruby, Therese Gründler, Danijel Kivaranovic, Paolo Fornara, Lukas Lusuardi, Clemens Brössner
Objective To investigate the efficacy and safety of the adjustable transobturator male system (ATOMS) in males with stress urinary incontinence (SUI) after transurethral resection of the prostate (TURP). Materials and methods From a large international prospectively administrated ATOMS-register we identified 49 patients with an ATOMS device due to persistent SUI after TURP. For evaluation males were divided into standard TURP (sTURP) and palliative/post radiation TURP (pTURP). Baseline and follow-up measurements included continence parameters, urodynamics, quality of life surveys (PGI-I, ICIQ-SF) and pain ratings...
July 13, 2017: Urology
https://www.readbyqxmd.com/read/28712540/aqueous-humor-tyrosinase-activity-is-indicative-of-iris-melanocyte-toxicity
#7
Sarmistha Mahanty, Ankush A Kawali, Shruthi Shirur Dakappa, Padmamalini Mahendradas, Mathew Kurian, Varun Kharbanda, Rohit Shetty, Subba Rao Gangi Setty
Antibiotics such as fluoroquinolones (FQLs) are commonly used to treat ocular infections but are also known to cause dermal melanocyte toxicity. The release of dispersed pigments from the iris into the aqueous humor has been considered a possible ocular side effect of the systemic administration of FQLs such as Moxifloxacin, and this condition is known as bilateral acute iris transillumination (BAIT). Bilateral acute depigmentation of iris (BADI) is a similar condition, with iris pigment released into the aqueous, but it has not been reported as a side effect of FQL...
July 13, 2017: Experimental Eye Research
https://www.readbyqxmd.com/read/28711221/the-evolution-of-lung-transplantation-for-cystic-fibrosis-a-2017-update
#8
REVIEW
Gregory Snell, Anna Reed, Marc Stern, Denis Hadjiliadis
Lung transplantation (LTx) is an established therapy for patients with end-stage cystic fibrosis (CF). Indeed, CF is the commonest indication for those aged<50years of age needing LTx. CF LTx is associated with a 45% 10year survival - according to the world's largest registry. It is important all otherwise suitable CF patients with severe lung disease have a timely referral for discussion and consideration of the possibility of LTx. LTx discussions must carefully consider colonisation or infection with Burkholderia cenocepacia, Mycobacterium abscessus and Scediosporium - as good LTx outcomes cannot be guaranteed...
July 12, 2017: Journal of Cystic Fibrosis: Official Journal of the European Cystic Fibrosis Society
https://www.readbyqxmd.com/read/28710739/prevention-and-management-of-post-operative-complications-following-acl-reconstruction
#9
REVIEW
Brian J Eckenrode, James L Carey, Brian J Sennett, Miltiadis H Zgonis
PURPOSE OF REVIEW: The goal of this paper is to review the current management and prevention of post-operative complications after anterior cruciate ligament (ACL) reconstruction. Trends in rehabilitation techniques will be presented, in addition to suggestions for interventions and expected milestones in ACL reconstruction recovery. RECENT FINDINGS: ACL reconstruction protocols have evolved to more of a criterion-based progression rather than a tissue-healing time frame...
July 14, 2017: Current Reviews in Musculoskeletal Medicine
https://www.readbyqxmd.com/read/28709485/biofilm-colonization-of-mycobacterium-abscessus-new-threat-in-hospital-acquired-surgical-site-infection
#10
Roumi Ghosh, Soumen Das, Harish Kela, Asmita De, Jayeeta Haldar, Prasanta Kumar Maiti
INTRODUCTION: Rapidly growing non-tuberculous mycobacteria (NTM) are hazardous cause of post-operative soft tissue infection leading to nosocomial outbreaks following various surgical procedures, especially laparoscopic surgeries using heat sensitive, non-autoclavable surgical instruments. METHODOLOGY: Surgery department of our hospital noticed increase in rate of post-laparoscopic abdominal port site infection (PSI) and informed the Microbiology Department. A prospective investigational study of defined cases with the aim of source tracing and formulation of infection control measures was initiated...
July 2017: Indian Journal of Tuberculosis
https://www.readbyqxmd.com/read/28708777/intraoperative-topical-antibiotics-for-infection-prophylaxis-in-pelvic-and-acetabular-surgery
#11
Matthew T Owen, Emily M Keener, Zane B Hyde, Reaves M Crabtree, Parke W Hudson, Russell L Griffin, Jason A Lowe
OBJECTIVES: Determine if topical vancomycin and tobramycin powder reduces the incidence of surgical site infection (SSI) following pelvic ring and acetabulum fracture surgery. DESIGN: Retrospective cohort study SETTING:: University of Alabama at Birmingham, Academic Level I Trauma Center PATIENTS/PARTICIPANTS:: 219 patients (140 meeting inclusion criteria) with pelvic and acetabular fractures who underwent open reduction and internal fixation (ORIF) from March 2012 to November 2013...
June 26, 2017: Journal of Orthopaedic Trauma
https://www.readbyqxmd.com/read/28708024/quality-improvement-initiative-preventative-surgical-site-infection-protocol-in-vascular-surgery
#12
David Parizh, Enrico Ascher, Syed Ali Raza Rizvi, Anil Hingorani, Michael Amaturo, Eric Johnson
Objective A quality improvement initiative was employed to decrease single institution surgical site infection rate in open lower extremity revascularization procedures. SUMMARY BACKGROUND DATA: In an attempt to lower patient morbidity, we developed and implemented the Preventative Surgical Site Infection Protocol in Vascular Surgery. Surgical site infections lead to prolonged hospital stays, adjunctive procedure, and additive costs. We employed targeted interventions to address the common risk factors that predispose patients to post-operative complications...
January 1, 2017: Vascular
https://www.readbyqxmd.com/read/28707270/profiling-of-cellular-microrna-responses-during-the-early-stages-of-kshv-infection
#13
Hosni A M Hussein, Shaw M Akula
Kaposi's sarcoma-associated herpesvirus (KSHV) causes a variety of cancers, including Kaposi's sarcoma (KS), primary effusion lymphoma (PEL), and multicentric Castleman disease (MCD). Host cellular microRNAs (miRNAs) play important post-transcriptional regulatory roles in gene expression and can greatly influence virus-host cell interactions. This study investigated cellular miRNA expression profiles operating in response to early stages of KSHV infection of human Burkitt lymphoma B cells (BJAB). We employed deep sequencing to analyze miRNA expression in KSHV-infected BJAB cells 15 min post infection (PI) and compared this to uninfected BJAB cells...
July 13, 2017: Archives of Virology
https://www.readbyqxmd.com/read/28706766/a-case-based-review-of-the-management-of-penetrating-brain-trauma
#14
Jason Milton, Alex Rugino, Kailash Narayan, Chris Karas, Victor Awuor
Principles of penetrating head trauma management were established by Harvey Cushing in relation to the management of penetrating brain injuries of World War One. Cushing radically debrided the scalp and skull and aggressively irrigated wound tracks to remove foreign bodies. He would then obtain water-tight closure. Cushing significantly decreased infection rates which reportedly limited the major cause of mortality due to penetrating head injuries. Many advances have been made by contributions from World War Two, Korean War, Vietnam War, and Iran/Iraq conflicts...
June 12, 2017: Curēus
https://www.readbyqxmd.com/read/28704331/mis-single-position-lateral-and-oblique-lateral-lumbar-interbody-fusion-and-bilateral-pedicle-screw-fixation-feasibility-and-perioperative-results
#15
Daniel J Blizzard, J Alex Thomas
STUDY DESIGN: Retrospective review of prospectively collected data of the first 72 consecutive patients treated with single-position one- or two-level lateral (LLIF) or oblique lateral interbody fusion (OLLIF) with bilateral percutaneous pedicle screw and rod fixation by a single spine surgeon. OBJECTIVE: To evaluate the clinical feasibility, accuracy, and efficiency of a single-position technique for LLIF and OLLIF with bilateral pedicle screw and rod fixation...
July 12, 2017: Spine
https://www.readbyqxmd.com/read/28702383/a-retrospective-study-of-titanium-elastic-stable-intramedullary-nailing-in-displaced-mid-shaft-clavicle-fractures
#16
Rajesh Govindasamy, Saravanan Kasirajan, Jimmy Joseph Meleppuram, Fawas Thonikadavath
OBJECTIVE: The aim of this study is to analyze the functional outcome following titanium elastic stable intra-medullary nailing (ESIN) for displaced mid-shaft clavicular fractures (DMCF). METHODS: A retrospective study of 60 patients between March 2009 and March 2015 was conducted. Patients were selected based on the inclusion criteria. Six patients were lost during follow up. Out of the remaining 54 patients, there were 39 males and 15 females. The mean age was 30...
May 2017: Revista Brasileira de Ortopedia
https://www.readbyqxmd.com/read/28699088/sepsis-prediction-in-critically-ill-patients-by-platelet-activation-markers-on-icu-admission-a-prospective-pilot-study
#17
Nathalie Layios, Céline Delierneux, Alexandre Hego, Justine Huart, Christian Gosset, Christelle Lecut, Nathalie Maes, Pierre Geurts, Arnaud Joly, Patrizio Lancellotti, Adelin Albert, Pierre Damas, André Gothot, Cécile Oury
BACKGROUND: Platelets have been involved in both immune surveillance and host defense against severe infection. To date, whether platelet phenotype or other hemostasis components could be associated with predisposition to sepsis in critical illness remains unknown. The aim of this work was to identify platelet markers that could predict sepsis occurrence in critically ill injured patients. METHODS: This single-center, prospective, observational, 7-month study was based on a cohort of 99 non-infected adult patients admitted to ICUs for elective cardiac surgery, trauma, acute brain injury, and post-operative prolonged ventilation and followed up during ICU stay...
December 2017: Intensive Care Medicine Experimental
https://www.readbyqxmd.com/read/28698419/-aortoesophageal-fistula-due-to-aortic-aneurysm-report-of-a-case
#18
Satoshi Yuhara, Takuya Kimura, Hideyuki Okawa, Hiroki Hasegawa, Jun Yokote, Yukifusa Yokoyama, Syuji Tamaki
A 77-year-old woman presented with general fatigue, was found to have anemia, and was referred to our hospital. Upper gastrointestinal endoscopy revealed a submucosal elevated lesion with a bleeding site and debris at the middle thoracic esophagus. Enhanced computed tomography demonstrated a thoracic aortic aneurysm compressing the esophagus. She was diagnosed with an aorto-esophageal fistula due to the thoracic aortic aneurysm. Graft replacement was performed under partial extracorporeal circulation. Because the perforation of the esophagus was small, omental flap transposition was performed without esophagectomy...
July 2017: Kyobu Geka. the Japanese Journal of Thoracic Surgery
https://www.readbyqxmd.com/read/28695707/comparison-of-long-term-clinical-outcomes-among-different-vascularized-lymph-node-transfers-6-year-experience-of-a-single-center-s-approach-to-the-treatment-of-lymphedema
#19
Pedro Ciudad, Mouchammed Agko, John Jaime Perez Coca, Oscar J Manrique, Wei-Ling Chang, Fabio Nicoli, Shih-Heng Chen, Hung-Chi Chen
BACKGROUND: This study evaluated the long-term clinical outcomes among different vascularized lymph node transfers (VLNT) used at our institution. METHODS: Between July 2010 and July 2016, all patients with International Society of Lymphology (ISL) stages II-III who underwent VLNT were evaluated. Demographic and clinical data (limb circumference, infectious episodes, lymphoscintigraphic studies) were recorded pre-operatively. Clinical outcomes, complications, and additional excisional procedures were analyzed post-operatively...
July 10, 2017: Journal of Surgical Oncology
https://www.readbyqxmd.com/read/28694086/an-outbreak-of-post-craniotomy-propionibacterium-acnes-infections-at-a-tertiary-hospital-england-2011-a-case-control-study-identifies-dural-implants-as-a-risk-factor-for-infection
#20
Caoimhe McKerr, Nic Coetzee, Obaghe Edeghere, Shakeel Suleman, Neville Q Verlander, Krishna Banavathi
BACKGROUND: In 2011, 15 deep-seated Propionibacterium acnes infections were identified in patients following craniotomies in a hospital in the UK. AIM: To describe the outbreak and report findings from the investigation undertaken in order to identify the source & risk factors and inform control measures. METHODS: Data were obtained from hospital clinical records and included patient and surgical variables. Cases were defined as patients with microbiologically confirmed deep or organ space surgical site infection (SSI) caused by P...
July 7, 2017: Journal of Hospital Infection
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