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Post operative infection

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https://www.readbyqxmd.com/read/28540784/safety-and-efficacy-of-radiofrequency-assisted-alpps-ralpps-in-patients-with-cirrhosis-related-hepatocellular-carcinoma
#1
Qiang Wang, Jun Yan, Xiaobin Feng, Geng Chen, Feng Xia, Xiaowu Li, Kuansheng Ma, Ping Bie
BACKGROUND AND AIMS: Associating liver partition and portal vein ligation for staged hepatectomy (ALPPS) has high morbidity and mortality. In this study, the safety and efficacy of a modification of ALPPS (radiofrequency-assisted ALPPS, RALPPS) were assessed in patients with hepatocellular carcinoma (HCC). MATERIALS AND METHODS: Patients who were diagnosed with HCC and were considered to have an insufficient future liver remnant (FLR) were enrolled. In stage I, a radiofrequency ablation (RFA) device was used to cauterise along the planned transection plane to form a coagulum avascular area...
March 23, 2017: International Journal of Hyperthermia
https://www.readbyqxmd.com/read/28540146/-combined-diagnostic-tool-application-to-a-retrospective-series-of-patients-undergoing-total-joint-revision-surgery
#2
Enrico Gallazzi, Lorenzo Drago, Andrea Baldini, Ian Stockley, David A George, Sara Scarponi, Carlo L Romanò
Background: Differentiating between septic and aseptic joint prosthesis may be challenging, since no single test is able to confirm or rule out infection. The choice and interpretation of the panel of tests performed in any case often relies on empirical evaluation and poorly validated scores. The "Combined Diagnostic Tool (CDT)" App, a smartphone application for iOS, was developed to allow to automatically calculate the probability of having a of periprosthetic joint infection, on the basis of the relative sensitivity and specificity of the positive and negative diagnostic tests performed in any given patient...
2017: J Bone Jt Infect
https://www.readbyqxmd.com/read/28537041/the-effect-of-antibiotic-prophylaxis-on-post-operative-infection-in-patients-undergone-flexible-cystos-copy
#3
Miguel Angel Arrabal-Polo, María Del Carmen Cano-García, Miguel Arrabal-Martín, Sergio Merino-Salas
PURPOSE: The aim of this study is to determine whether antibiotic prophylaxis is required in this outpatient procedure. MATERIALS AND METHODS: A non-randomised, prospective observational study that included 184 patients subjected to flexible cystoscopy divided into three groups: - Group 1:60 patients with prophylaxis of 500 mg of ciprofloxacin;- Group 2:62 patients with prophylaxis of 3 g of phosphomycin; and Group 3:62 without antibiotic prophylaxis. Prior to inclusion in the study, absence of infection was checked by means of a urine culture obtained 7 days before the procedure...
May 23, 2017: Urology Journal
https://www.readbyqxmd.com/read/28536044/free-tissue-transfer-for-necrotizing-fasciitis-reconstruction-a-case-series
#4
Justin Peter Gawaziuk, Tianyi Liu, Leif Sigurdson, Edward Buchel, Thomas Edward Jo Hayakawa, Sarah Shiga, Sarvesh Logsetty
BACKGROUND: Necrotizing fasciitis (NF) is a life-threatening infection requiring extensive debridement that may necessitate amputation. Free tissue transfer (FTT) is an option for reconstruction in difficult cases. Currently, only case reports have described FTT in the setting of NF, and comprehensive evidence on flap outcomes is lacking. The present study characterizes outcomes in patients with FTT following NF. METHODS: All patients admitted with NF between January 1, 2005 and December 31, 2011 to our level 1 burns/trauma referral center were retrospectively reviewed...
May 20, 2017: Burns: Journal of the International Society for Burn Injuries
https://www.readbyqxmd.com/read/28532856/implementation-of-a-referral-to-discharge-glycemic-control-initiative-for-reduction-of-surgical-site-infections-in-gynecologic-oncology-patients
#5
Laura Hopkins, Jennifer Brown-Broderick, James Hearn, Janine Malcolm, James Chan, Wendy Hicks-Boucher, Filomena De Sousa, Mark C Walker, Sylvain Gagné
OBJECTIVE(S): To evaluate the frequency of surgical site infections before and after implementation of a comprehensive, multidisciplinary perioperative glycemic control initiative. STUDY METHODS: As part of a CUSP (Comprehensive Unit-based Safety Program) initiative, between January 5 and December 18, 2015, we implemented comprehensive, multidisciplinary glycemic control initiative to reduce SSI rates in patients undergoing major pelvic surgery for a gynecologic malignancy ('Group II')...
May 20, 2017: Gynecologic Oncology
https://www.readbyqxmd.com/read/28532076/sustained-drug-release-from-surface-modified-uhmwpe-for-acetabular-cup-lining-in-total-hip-implant
#6
R Manoj Kumar, Pallavi Gupta, Sandan Kumar Sharma, Akshat Mittal, Manish Shekhar, Vijayesh Kumar, B V Manoj Kumar, Partha Roy, Debrupa Lahiri
Despite sterilization and aseptic procedure, bacterial infection remains a key challenge in total hip arthroplasties. This fact emphasizes the urgent need for development of new implant systems, which should releases the drug in a controlled manner without sparing its mechanical and tribological properties. In this study, the lining material of the acetabular cup, in total hip implant, has been modified for sustained release of drugs, which should be available throughout the site of implantation to fight the post-operation bacterial infection...
August 1, 2017: Materials Science & Engineering. C, Materials for Biological Applications
https://www.readbyqxmd.com/read/28526242/factors-predicting-complications-after-sacral-neuromodulation-in-children
#7
Molly E Fuchs, Peter L Lu, Stephanie J Vyrostek, Steven Teich, Seth A Alpert
OBJECTIVES: To identify if any pre-operative variable are associated with post-operative complications after pediatric sacral neuromodulation (SNM). METHODS: A review of all patients undergoing SNM with an implantable pulse generator at our institution was performed. Post-operative infection, lead migration, lead breakage and need for reoperation were recorded in a prospective database. We collected demographic information and indication for the procedure. We defined indication for procedure as either primarily bowel, or primarily bladder symptoms...
May 16, 2017: Urology
https://www.readbyqxmd.com/read/28522380/predictive-factors-of-postoperative-seizure-for-pediatric-patients-with-unruptured-arteriovenous-malformations-avms
#8
Haibo Yang, Zhenghai Deng, Wuyang Yang, Kai Liu, Hongxin Yao, Xianzeng Tong, Jun Wu, Yuanli Zhao, Yong Cao, Shuo Wang
BACKGROUND: Seizure is the second-most common presentation in AVM patients and superimposes significant burden on pediatric patients. Post-operative seizure risk in unruptured AVMs is under-reported in the pediatric AVM literature. We aim to characterize and identify predictive factors for post-operative seizures in this study. METHODS: We performed a retrospective review of all surgically treated, unruptured pediatric AVM patients at our institution from 2001-2014...
May 15, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/28522207/outcomes-of-post-traumatic-tibial-osteomyelitis-treated-with-an-orthofix-lrs-versus-an-ilizarov-external-fixator
#9
Yilizati Yilihamu, Ajimu Keremu, Alimujiang Abulaiti, Xiayimaierdan Maimaiti, Peng Ren, Aihemaitijiang Yusufu
OBJECTIVE: To compare the therapeutic effects of the Orthofix limb reconstruction system (LRS) versus the Ilizarov external fixator on osteomyelitis of a tibial bone defect. MATERIALS AND METHODS: Among 153 patients hospitalized for bone lengthening therapy from January 1, 1996 to January 1, 2015, 129 patients were selected for a retrospective analysis. Forty-three of the candidate patients were treated using the Orthofix LRS and the other 86 were treated using an Ilizarov external fixator...
May 3, 2017: Injury
https://www.readbyqxmd.com/read/28512755/evaluation-of-safety-of-concomitant-splenectomy-in-living-donor-liver-transplantation
#10
Amr Badawy, Yuhei Hamaguchi, Satoru Seo, Tochimi Kaido, Hideaki Okajima, Shinji Uemoto
In Asian countries, concomitant splenectomy in living donor liver transplantation (LDLT) is indicated to modulate the portal vein pressure in the small sized graft to protect against small for size syndrome. While concomitant splenectomy in deceased donor liver transplantation is almost contraindicated based on western reports of increased mortality and morbidity rate due to septic complications, there are few studies about that in LDLT. So, we retrospectively investigated the clinical outcome of adult LDLT at Kyoto University Hospital from July 2010 to July 2016...
May 17, 2017: Transplant International: Official Journal of the European Society for Organ Transplantation
https://www.readbyqxmd.com/read/28512612/review-of-cranioplasty-after-decompressive-craniectomy
#11
REVIEW
Yong Jun Cho, Suk Hyung Kang
Cranioplasty is an in evitable operation conducted after decompressive craniectomy (DC). The primary goals of cranioplasty after DC are to protect the brain, achieve a natural appearance and prevent sinking skin flap syndrome (or syndrome of the trephined). Furthermore, restoring patients' functional outcome and supplementing external defects helps patients improve their self-esteem. Although early cranioplasty is preferred in recent year, optimal timing for cranioplasty remains a controversial topic. Autologous bone flaps are the most ideal substitute for cranioplasty...
April 2017: Korean Journal of Neurotrauma
https://www.readbyqxmd.com/read/28508765/a-comparison-of-outcomes-of-treatment-with-resection-prosthesis-of-the-hip-in-revision-and-oncological-surgery
#12
Paweł Kamiński, Jakub Szmyd, Jarosław Ambroży, Jerzy Mirosław Jaworski, Bogusław Frańczuk
INTRODUCTION: The introduction of resection prostheses paved the way for the development of limb-sparing surgery in patients with primary or metastatic bone tumours. After some time, the developing possibilities of treatment of extensive bone defects allowed for the use of resection prostheses as an emergency procedure in patients undergoing revision surgery due to hip implant loosening. The aim of this paper is to compare treatment outcomes in patients receiving the Modular Universal Tumour and Revision System (MUTARS) resection prosthesis during arthroplasty performed for different indications: treatment of a tumour metastasis and revision surgery in cases of implant loosening...
April 12, 2017: Ortopedia, Traumatologia, Rehabilitacja
https://www.readbyqxmd.com/read/28507961/total-hip-arthroplasty-indicated-for-a-tuberculous-coxitis-complicating-a-controlled-acquired-imunodefficiency-syndrom-condition-a-preliminary-report-concerning-a-case
#13
Handy Eone Daniel, Jean Emile Bayiha, Théophyle Chunteng Nana, Olivier Kennedy Muluem, Jean Bahebeck
INTRODUCTION: Total hip arthroplasty (THA) remains controversial in active tuberculosis (TB) infection because of the risks of septic loosening and reactivation of the infection. We present a rare case of THA in a patient positive for the human immunodeficiency virus (HIV) with active tuberculous coxitis. The aim of this work is to share our experience and our preliminary results. CASE REPORT: The patient was a 53-year-old Black African woman, positive for the HIV, who was operated for implantation of a THA via the Hardinge approach indicated for a severe painful hip with restriction of joint movement and limp...
November 2016: Journal of Orthopaedic Case Reports
https://www.readbyqxmd.com/read/28507783/periprosthetic-shoulder-infection-an-overview
#14
REVIEW
Nicolas Bonnevialle, Florence Dauzères, Julien Toulemonde, Fanny Elia, Jean-Michel Laffosse, Pierre Mansat
Periprosthetic shoulder infection (PSI) is rare but potentially devastating. The rate of PSI is increased in cases of revision procedures, reverse shoulder implants and co-morbidities. One specific type of PSI is the occurrence of low-grade infections caused by non-suppurative bacteria such as Propionibacterium acnes or Staphylococcus epidemermidis.Success of treatment depends on micro-organism identification, appropriate surgical procedures and antibiotic administration efficiency. Post-operative early PSI can be treated with simple debridement, while chronic PSI requires a one- or two-stage revision procedure...
April 2017: EFORT Open Rev
https://www.readbyqxmd.com/read/28507468/paradoxical-effect-of-minocycline-on-established-neuropathic-pain-in-rat
#15
Malek Zarei, Masoumeh Sabetkasaei, Taraneh Moini-Zanjani
Neuropathic pain occurs after peripheral nerve damage, inflammation or infection. In this situation, microglial cells become activated and play a key role in producing pain. Minocycline (microglia inhibitor), was reported to reduce pain when used preventively. However, it seems that, when used after nerve injury, results in its pain reducing effects are different. In this regard, to assess the pain reducing differences of minocycline, neuropathic pain was induced by the ligation of the sciatic nerve in the rat which is recognized as chronic constriction injury (CCI) and minocycline was administered before and after sciatic nerve injury...
2017: EXCLI journal
https://www.readbyqxmd.com/read/28507349/antibiotics-in-acute-calculous-cholecystitis-do-tokyo-guidelines-influence-the-surgeons-practices
#16
Hassaan Bari, Muhammad Rizwan Khan, Amir Hafeez Shariff
OBJECTIVE: To observe changes in surgeons' practice of antibiotic usage in patients with acute cholecystitis before and after the implementation of Tokyo Guidelines. METHODS: This retrospective, descriptive study was conducted at the Aga Khan University Hospital, Karachi, and comprised the medical records of all patients with the diagnosis of acute calculus cholecystitis who presented in 2009 and those who presented in 2014 after the implementation of Tokyo Guidelines...
May 2017: JPMA. the Journal of the Pakistan Medical Association
https://www.readbyqxmd.com/read/28505570/clinical-evaluation-of-the-biofire-filmarray-%C3%A2-biothreat-e-test-for-the-diagnosis-of-ebola-virus-disease-in-guinea
#17
Françoise Gay-Andrieu, N'Fally Magassouba, Valentina Picot, Cynthia L Phillips, Christophe N Peyrefitte, Brigitte Dacosta, Ahmadou Doré, Fode Kourouma, Véronique Ligeon-Ligeonnet, Corentin Gauby, Christophe Longuet, Matt Scullion, Ousmane Faye, Jean Louis Machuron, Mark Miller
BACKGROUND: The recent West Africa Ebola outbreak highlighted the need to provide access to rapid, safe and reliable Ebola Virus Disease diagnostics. OBJECTIVES: The objective of this field study was to assess the clinical performance of the FilmArray(®) BioThreat-E test for the detection of Ebola Zaïre virus in whole blood in symptomatic patients suspected of Ebola Virus Disease in Conakry (Guinea) from March to July 2015. STUDY DESIGN: The BioThreat-E test was compared to the two RT-PCRs, using serum, implemented at Donka Hospital in the emergency context: an in-house developed quantitative one-step RT-PCR adapted from the Weidmann technique, and the RealStar(®) Filovirus RT-PCR Kit 1...
May 1, 2017: Journal of Clinical Virology: the Official Publication of the Pan American Society for Clinical Virology
https://www.readbyqxmd.com/read/28505031/povidone-iodine-solutions-inhibit-cell-migration-and-survival-of-osteoblasts-fibroblasts-and-myoblasts
#18
James X Liu, Jordan A Werner, John A Buza, Thorsten Kirsch, Joseph D Zuckerman, Mandeep S Virk
STUDY DESIGN: In vitro laboratory study. OBJECTIVE: The purpose of this study was to identify the effect of dilute povidone-iodine (PVI) solutions on human osteoblast, fibroblast and myoblast cells in vitro. SUMMARY OF BACKGROUND DATA: Dilute PVI wound lavage has been used successfully in spine and joint arthroplasty procedures to prevent post-operative surgical site infection, but their biologic effect on host cells is largely unknown. METHODS: Human primary osteoblasts, fibroblasts, and myoblasts were expanded in cell culture and subjected to various concentrations of PVI (0%, 0...
April 12, 2017: Spine
https://www.readbyqxmd.com/read/28504874/cranioplasty-with-adipose-derived-stem-cells-beta-tricalcium-phosphate-granules-and-supporting-mesh-six-year-clinical-follow-up-results
#19
Tuomo Thesleff, Kai Lehtimäki, Tero Niskakangas, Sanna Huovinen, Bettina Mannerström, Susanna Miettinen, Riitta Seppänen-Kaijansinkko, Juha Öhman
Several alternative techniques exist to reconstruct skull defects. The complication rate of the cranioplasty procedure is high and the search for optimal materials and techniques continues. To report long-term results of patients who have received a cranioplasty using autologous adipose-derived stem cells (ASCs) seeded on beta-tricalcium phosphate (betaTCP) granules. Between 10/2008 and 3/2010, five cranioplasties were performed (four females, one male; average age 62.0 years) using ASCs, betaTCP granules and titanium or resorbable meshes...
May 15, 2017: Stem Cells Translational Medicine
https://www.readbyqxmd.com/read/28503302/reliability-and-validity-of-using-telephone-calls-for-post-discharge-surveillance-of-surgical-site-infection-following-caesarean-section-at-a-tertiary-hospital-in-tanzania
#20
Boniface Nguhuni, Pasquale De Nardo, Elisa Gentilotti, Zainab Chaula, Caroline Damian, Paola Mencarini, Emanuele Nicastri, Arnold Fulment, Alessandro Piscini, Francesco Vairo, Alexander M Aiken, Giuseppe Ippolito
BACKGROUND: Surgical site infection (SSI) is a common post-operative complication causing significant morbidity and mortality. Many SSI occur after discharge from hospital. Post-discharge SSI surveillance in low and middle income countries needs to be improved. METHODOLOGY: We conducted an observational cohort study in Dodoma, Tanzania to examine the sensitivity and specificity of telephone calls to detect SSI after discharge from hospital in comparison to a gold standard of clinician review...
2017: Antimicrobial Resistance and Infection Control
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