keyword
MENU ▼
Read by QxMD icon Read
search

Organophosphate

keyword
https://www.readbyqxmd.com/read/29148167/monitoring-resistance-of-cydia-pomonella-l-spanish-field-populations-to-new-chemical-insecticides-and-the-mechanisms-involved
#1
Dolors Bosch, Marcela A Rodríguez, Jesús Avilla
BACKGROUND: A widespread resistance of Cydia pomonella to organophosphates was demonstrated in populations from the Spanish Ebro Valley area that showed high levels of enzymatic detoxification. To determine the efficacy of new insecticides, neonate larvae bioassays were carried out on twenty field codling moth populations collected from three different Spanish apple production areas. Synergist bioassays were performed to detect the enzymatic mechanisms involved. RESULTS: The least active ingredients were methoxyfenozide, with 100% of the populations showing significantly lower mortality than the susceptible strain, and lambda-cyhalothrin, with very high resistant ratios (872...
November 16, 2017: Pest Management Science
https://www.readbyqxmd.com/read/29147747/isomers-of-tris-chloropropyl-phosphate-tcpp-in-technical-mixtures-and-environmental-samples
#2
Jimmy W Truong, Miriam L Diamond, Paul A Helm, Liisa M Jantunen
Tris(chloropropyl) phosphate (TCPP) is an environmentally abundant organophosphate ester (OPE). TCPP is comprised of four isomers with seven possible structures, eight CAS numbers, and even more common names. A review of 54 studies reporting one or more TCPP isomers confirmed that the most abundant and most often reported TCPP isomer was tris(2-chloro-1-methylethyl) phosphate, also known as tris(chloroisopropyl) phosphate (TCiPP, referred to hereafter as TCPP1). Full-scan gas chromatography-mass spectrometry (GC-MS) was used to identify the other three isomers numbered here according to their elution order on a non-polar GC column (DB-5): bis(2-chloro-1-methylethyl) (2-chloropropyl) phosphate (TCPP2), bis(2-chloropropyl)(2-chloro-1-methylethyl) phosphate (TCPP3), and tris(2-chloropropyl) phosphate (TCPP4)...
November 16, 2017: Analytical and Bioanalytical Chemistry
https://www.readbyqxmd.com/read/29147079/laboratory-evaluation-of-residual-efficacy-of-actellic-300-cs-pirimiphos-methyl-and-k-othrine-wg-250-deltamethrin-on-different-indoor-surfaces
#3
Kolade T Ibrahim, Kehinde O Popoola, Kenneth O Akure
The nature and type of local indoor resting wall surfaces to certain level influences the residual bio-efficacy of insecticides used in indoor residual spraying programs. Knockdown and mortality effects of an organophosphate Actellic 300 CS and pyrethroid K-Othrine WG 250 insecticides on the field-collected Culex quinquefasciatus were assessed bimonthly from July to November 2014, using World Health Organization (WHO) cones bioassay test. Knockdown and mortality rates were subjected to statistical analysis using χ(2) and Student t tests...
2017: International Journal of Insect Science
https://www.readbyqxmd.com/read/29143548/evaluation-on-the-thyroid-disrupting-mechanism-of-malathion-in-fischer-rat-thyroid-follicular-cell-line-frtl-5
#4
Jingyuan Xiong, Liantian Tian, Yongjie Qiu, Ding Sun, Hao Zhang, Mei Wu, Jintao Wang
Thyroid hormones are involved in many important physiological activities including regulation of energy metabolism, development of nervous system, maintenance of cerebral functions, and so on. Endocrine-disrupting chemicals (EDCs) that interfere with thyroid functions raise serious concerns due to their frequent misuse in areas where regulations are poorly implemented. In addition, chemicals that are originally regarded safe may now be considered as toxic with the development of life sciences. Malathion is an organophosphate insecticide that is widely applied and distributed in agricultural and residential settings...
November 16, 2017: Drug and Chemical Toxicology
https://www.readbyqxmd.com/read/29143438/protective-effects-of-coenzyme-q10-nanoparticles-on-dichlorvos-induced-hepatotoxicity-and-mitochondrial-lysosomal-injury
#5
Aziz Eftekhari, Elham Ahmadian, Aida Azami, Mohammad Johari-Ahar, Mohammad Ali Eghbal
Development of biocompatible antioxidant nanoparticles for xenobiotic-induced liver disease treatment by oral or parenteral administration is of great interest in medicine. In the current study, we demonstrate the protective effects of coenzyme Q10 nanoparticles (CoQ10-NPs) on hepatotoxicity induced by dichlorvos (DDVP) as an organophosphate. Although CoQ10 is an efficient antioxidant, its poor bioavailability has limited the applications of this useful agent. First, CoQ10-NPs were prepared then characterized using dynamic light scattering (DLS) and transmission electron microscopy (TEM)...
November 16, 2017: Environmental Toxicology
https://www.readbyqxmd.com/read/29143350/dna-variants-and-organophosphate-neurotoxicity-among-emerging-farmers-in-the-western-cape-of-south-africa
#6
Tracy Glass, Mohamed A Dalvie, Zelda Holtman, Anna A Vorster, Rajkumar S Ramesar, Leslie London
BACKGROUND: Previous epidemiological studies investigating modification of organophosphate (OP) neurotoxicity by xenobiotic metabolizing enzymes (XMEs) polymorphisms have produced inconsistent results. METHODS: A cross-sectional study of 301 emerging farmers was conducted. Neurotoxicity testing included forward and backward recall, digit span, and vibration sensitivity testing. Questionnaire data included demography, potential confounders, and work history of pesticide exposures...
November 16, 2017: American Journal of Industrial Medicine
https://www.readbyqxmd.com/read/29142799/respiratory-failure-following-organophosphate-poisoning-a-literature-review
#7
REVIEW
Pirthvi Raj Giyanwani, Ujala Zubair, Osama Salam, Zarafshan Zubair
Organophosphates (OPs) account for a large portion of suicides globally. OP manifests as cholinergic crises, which underlie respiratory failure. There are many pathways by which respiration is inhibited secondary to organophosphate poisoning. These include central as well as peripheral mechanisms, with central mechanisms predominating. We conducted a literature review in June 2017. PubMed, Embase, and Google Scholar were searched for studies that reported acute organophosphate poisoning in humans. In our review, data were collected from studies published during the years 2001 to 2016...
September 3, 2017: Curēus
https://www.readbyqxmd.com/read/29141517/protective-effects-of-dietary-omega-3-fatty-acid-supplementation-on-organophosphate-poisoning
#8
Bahattin Avci, S Sirri Bilge, Gokhan Arslan, Omer Alici, Ozge Darakci, Turkhan Baratzada, Engin Ciftcioglu, Turker Yardan, Ayhan Bozkurt
In this study, we aimed to study the possible preventive effect of docosahexaenoic acid (DHA), a dietary omega-3 fatty acid, on toxicity caused by chlorpyrifos (CPF). Six groups of Sprague Dawley rats (200-250 g) consisting of equal numbers of males and females (n = 8) were assigned to study. The rats were orally given for 5 days. The control group was administered pure olive oil, which was the vehicle for CPF. The CPF challenge groups were administered oral physiological saline, pure olive oil, or DHA (50, 100 and 400 mg/kg dosages) for 5 days...
January 1, 2017: Toxicology and Industrial Health
https://www.readbyqxmd.com/read/29139620/changing-patterns-in-water-toxicity-associated-with-current-use-pesticides-in-three-california-agriculture-regions
#9
Brian S Anderson, Bryn M Phillips, Jennifer P Voorhees, Xin Deng, Jeff Geraci, Karen Worcester, Ron S Tjeerdema
Regulation of agriculture irrigation water discharges in California is assessed and controlled by its nine Regional Water Quality Control Boards under the jurisdiction of the California State Water Resources Control Board. Each Regional Water Board has developed programs to control pesticides in runoff as part of the waste discharge requirements implemented through each Region's Irrigated Lands Regulatory Program. This study assessed how pesticide use patterns differ in the Imperial (Imperial County), Salinas and Santa Maria (Monterey County) valleys, which host three of California's prime agriculture areas...
November 15, 2017: Integrated Environmental Assessment and Management
https://www.readbyqxmd.com/read/29130673/-detection-of-11-organophosphate-pesticides-and-atrazine-in-water-by-dispersive-liquid-liquid-microextraction-combined-with-gas-chromatography-mass-spectrometry
#10
Chun-Yan Wang, Yue Yuan, Qian Wang, Ming-Xin Li, Pin-Pin Long, Xiao-Li Zou
OBJECTIVE: To develop a method for detecting 11 organophosphate pesticides and atrazine in water samples by dispersive liquidliquid microextraction combined with gas chromatographymass spectrometry (DLLMEGC/MS) . METHODS: DLLME and GCMS parameters were optimized for efficient extraction of chemicals. The proposed method was used for detecting organophosphate pesticides in tap water and river water samples,with 200 μL of dimethylbenzene as extractant and 800 μL of methanol as dispersant...
September 2017: Sichuan da Xue Xue Bao. Yi Xue Ban, Journal of Sichuan University. Medical Science Edition
https://www.readbyqxmd.com/read/29129799/post-exposure-treatment-with-the-oxime-rs194b-rapidly-reactivates-and-reverses-advanced-symptoms-of-lethal-inhaled-paraoxon-in-macaques
#11
Yvonne J Rosenberg, Jerry Wang, Tara Ooms, Narayanan Rajendran, Lingjun Mao, Xiaoming Jiang, Jonathan Lees, Lori Urban, Jeremiah Romper, Yadire Sepulveda, Yan-Jye Shyong, Palmer Taylor
Fatalities from organophosphate (OP) insecticide result from both occupational and deliberate exposure; significantly impacting human health. Like nerve agents, insecticides are neurotoxins which target and inhibit acetylcholinesterases (AChE) in central and peripheral synapses in the cholinergic nervous system. Post-exposure therapeutic countermeasures generally include administration of atropine with a pyridinium aldoximes e.g. pralidoxime, to reactivate the OP-inhibited AChE. However, commonly used oximes inefficiently cross the blood brain barrier and are rapidly cleared and their benefit is debated...
November 9, 2017: Toxicology Letters
https://www.readbyqxmd.com/read/29129621/tdcpp-protects-cardiomyocytes-from-hypoxia-reoxygenation-injury-induced-apoptosis-through-mitigating-calcium-overload-and-promotion-gsk-3%C3%AE-phosphorylation
#12
Xiju He, Shoutian Li, Xiaoxia Fang, Yanhong Liao
TDCPP, Tris (1, 3-dichloro-2-propyl) phosphate belongs to a group of chemicals known as triester organophosphate flame retardants, It can alter calcium homeostasis at much lower concentrations in normal conditions, but the mechanism is unclear till now. Calcium overload is a leading cause of apoptosis in myocardial ischemia/reperfusion (I/R) injury, thus how to mitigate Ca(2+)-overload is deserved to be investigated. We therefore hypothesized that TDCPP could attenuate cardiomyocytes apoptosis in I/R injury...
November 9, 2017: Regulatory Toxicology and Pharmacology: RTP
https://www.readbyqxmd.com/read/29128639/degradation-of-pesticides-with-rsdl-%C3%A2-reactive-skin-decontamination-lotion-kit-lotion-lc-ms-investigation
#13
Messele Fentabil, Mulu Gebremedhin, J Garfield Purdon, Laura Cochrane, Virginia Streusand Goldman
This study examined the degradation of organophosphate (OP) and carbamate pesticides using RSDL(®) (Reactive Skin Decontamination Lotion Kit) lotion. Degradation occurs from a nucleophilic substitution (SN) reaction between an ingredient in the RSDL lotion, potassium 2,3-butanedione monoximate (KBDO), with susceptible sites in the pesticides. Evaluation at several molar ratios of KBDO:test articles using liquid chromatography-mass spectrometry (LC-MS) techniques was performed. The OP test articles, parathion, paraoxon, parathion-methyl, paraoxon-methyl and chlorpyrifos were effectively degraded at molar ratios of four and above in less than 6minutes contact time...
November 8, 2017: Toxicology Letters
https://www.readbyqxmd.com/read/29125288/uptake-translocation-and-biotransformation-of-organophosphorus-esters-in-wheat-triticum-aestivum-l
#14
Weining Wan, Honglin Huang, Jitao Lv, Ruixia Han, Shuzhen Zhang
The uptake, translocation and biotransformation of organophosphate esters (OPEs) by wheat (Triticum aestivum L.) were investigated by a hydroponic experiment. The results demonstrated that OPEs with higher hydrophobicity were more easily taken up by roots, and OPEs with lower hydrophobicity were more liable to be translocated acropetally. A total of 43 metabolites including dealkylated, oxidatively dechlorinated, hydroxylated, methoxylated, and glutathione- and glucuronide- conjugated products were detected derived from eight OPEs, with di-esters formed by direct dealkylation from the parent tri-esters as the major products, followed with hydroxylated tri-esters...
November 10, 2017: Environmental Science & Technology
https://www.readbyqxmd.com/read/29123163/imidacloprid-and-chlorpyrifos-insecticides-impair-migratory-ability-in-a-seed-eating-songbird
#15
Margaret L Eng, Bridget J M Stutchbury, Christy A Morrissey
Birds that travel long distances between their wintering and breeding grounds may be particularly susceptible to neurotoxic insecticides, but the influence of insecticides on migration ability is poorly understood. Following acute exposure to two widely used agricultural insecticides, imidacloprid (neonicotinoid) and chlorpyrifos (organophosphate), we compared effects on body mass, migratory activity and orientation in a seed-eating bird, the white-crowned sparrow (Zonotrichia leucophrys). During spring migration, sparrows were captured, held and dosed by gavage daily for 3 days with either the vehicle control, low (10% LD50) or high (25% LD50) doses of imidacloprid or chlorpyrifos and tested in migratory orientation trials pre-exposure, post-exposure and during recovery...
November 9, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29121537/permethrin-drastically-affects-the-developmental-cycle-of-the-non-target-slime-mould-dictyostelium-discoideum
#16
Andrea Amaroli, Lorenzo Gallus, Sara Ferrando
The use of pyrethroids has increased throughout the world over the past few decades, as organophosphate, carbamate and organochlorine insecticides are being phased out. Permethrin is widely used in the USA for crops treatment, at concentrations around 750 × 10(3) μg/L. In our study 3.6 μg/L permethrin decreases the fission-rate and the fruiting bodies formation of slime mould Dictyostelium discoideum. Whereas 3.6 × 10(4) μg/L kills the 100% of amoebae, showing a 24 h-LC50 = 96.6 μg/L. This concentration induces an increase in the pseudocholinesterase activity as well as in both butyrylcholinesterase and heat-shock-protein 70 presence...
October 26, 2017: Chemosphere
https://www.readbyqxmd.com/read/29119330/analysis-of-factors-controlling-sediment-phosphorus-flux-potential-of-wetlands-in-hulun-buir-grassland-by-principal-component-and-path-analysis-method
#17
Jing He, Derong Su, Shihai Lv, Zhaoyan Diao, Shengxing Ye, Zhirong Zheng
Phosphorus (P) flux potential can predict the trend of phosphorus release from wetland sediments to water and provide scientific parameters for further monitoring and management for phosphorus flux from wetland sediments to overlying water. Many studies have focused on factors affecting sediment P flux potential in sediment-water interface, but rarely on the relationship among these factors. In the present study, experiment on sediment P flux potential in sediment-water interface was conducted in six wetlands in Hulun Buir grassland, China and the relationships among sediment P flux potential in sediment-water interface, sediment physical properties, and sediment chemical characteristics were examined...
November 8, 2017: Environmental Monitoring and Assessment
https://www.readbyqxmd.com/read/29115819/whole-life-stage-characterization-in-the-basic-biology-of-daphnia-magna-and-effects-of-tdcipp-on-growth-reproduction-survival-and-transcription-of-genes
#18
Han Li, Siliang Yuan, Guanyong Su, Meng Li, Qiangwei Wang, Guonian Zhu, Robert J Letcher, Yufei Li, Zhihua Han, Chunsheng Liu
Toxicity tests of chemicals have mainly focused on the partial life-cycle evaluation of model animals. Limited information is available for the evaluation of effects of chemicals from a whole-life-stage exposure perspective. The objective of this study was to perform a whole-life-stage characterization in the basic biology of Daphnia magna (D. magna) and evaluate the effects of a known organophosphate ester (OPE) contaminant, tris(1,3-dichloro-2-propyl) phosphate (TDCIPP), on growth, reproduction, survival, and transcription of genes...
November 17, 2017: Environmental Science & Technology
https://www.readbyqxmd.com/read/29115090/urine-methyl-hippuric-acid-levels-in-acute-pesticide-poisoning-estimation-of-ingested-xylene-volume-and-association-with-clinical-outcome-parameters
#19
Chi Young Choi, NamJun Cho, Su Yeon Park, Samel Park, Hyo Wook Gil, Sae Yong Hong
To determine the relationship between the oral ingestion volume of xylene and methyl hippuric acid (MHA) in urine, we measured MHA in 11 patients whose ingested xylene volume was identified. The best-fit equation between urine MHA and ingested amount of xylene was as follows: y (ingested amount of xylene, mL/kg) = -0.052x² + 0.756x (x = MHA in urine in g/g creatinine). From this equation, we estimated the ingested xylene volume in 194 patients who had ingested pesticide of which the formulation was not available...
December 2017: Journal of Korean Medical Science
https://www.readbyqxmd.com/read/29113434/similar-active-sites-and-mechanisms-do-not-lead-to-cross-promiscuity-in-organophosphate-hydrolysis-implications-for-biotherapeutic-engineering
#20
Miha Purg, Mikael Elias, Shina Caroline Lynn Kamerlin
Organophosphate hydrolases are proficient catalysts of the breakdown of neurotoxic organophosphates, and have great potential as both biotherapeutics for treating acute organophosphate toxicity, and as bioremediation agents. Yet proficient organophosphatases such as serum paraoxonase 1 (PON1) and the organophosphate-hydrolyzing lactonase SsoPox are unable to hydrolyze organophosphates with challenging leaving groups such as diisopropyl fluorophosphate (DFP) or venomous agent X (VX), creating a major challenge for enzyme design...
November 7, 2017: Journal of the American Chemical Society
keyword
keyword
22969
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"