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https://www.readbyqxmd.com/read/29164612/seizures-csf-neurofilament-light-and-tau-in-patients-with-subarachnoid-haemorrhage
#1
I Halawa, P Vlachogiannis, Å Amandusson, K Elf, E-R Engström, H Zetterberg, E Kumlien
OBJECTIVES: Patients with severe subarachnoid haemorrhage (SAH) often suffer from complications with delayed cerebral ischaemia (DCI) due to vasospasm that is difficult to identify by clinical examination. The purpose of this study was to monitor seizures and to measure cerebrospinal fluid (CSF) concentrations of neurofilament light (NFL) and tau, and to see whether they could be used for predicting preclinical DCI. METHODS: We prospectively studied 19 patients with aneurysmal SAH who underwent treatment with endovascular coiling...
November 21, 2017: Acta Neurologica Scandinavica
https://www.readbyqxmd.com/read/29151489/an-infectious-pseudoaneurysm-caused-by-ventricular-septal-defect-occluder-in-patent-ductus-arteriosus-closure-in-a-two-year-old-child
#2
Dingyang Li, Qiu Qiu, Jing Jin, Changdong Zhang, Lijun Wang, Gangcheng Zhang
We present a case of an infectious pseudoaneurysm after patent ductus arteriosus (PDA) closure with a ventricular septal defect (VSD) occluder in a two-year-old child. The aneurysm grew rapidly but was successfully removed in time and the patient survived. To our knowledge, this is the first report of an infectious pseudoaneurysm caused by VSD occluder in PDA closure.
November 17, 2017: International Heart Journal
https://www.readbyqxmd.com/read/29142814/a-membranous-septal-aneurysm-causing-right-ventricular-outflow-tract-obstruction-in-an-adult
#3
Fiorella Privitera, Ines Paola Monte, Antonino Indelicato, Corrado Tamburino
We describe a case of a 69-year-old female referred for the evaluation of exertional dyspnea, with a small membranous ventricular septal defect (VSD) and right ventricle (RV) outflow tract obstruction. Using transthoracic echo was diagnosed VSD with left to right shunting and transesophageal echo (TEE) was used to a better anatomical characterization. TEE showed a perimembranous subaortic VSD that developed a high-velocity flow in RV. Pulmonary valve appears normal and right ventricular infundibular hypertrophy or double-chambered RV was excluded from the study...
October 2017: Journal of Cardiovascular Echography
https://www.readbyqxmd.com/read/29141859/unique-pattern-of-aortic-regurgitation-caused-by-rupture-into-the-left-ventricular-interleaflet-triangle-of-a-sinus-valsalva-aneurysm-involving-the-left-coronary-cusp
#4
Yasuhide Mochizuki, Kazuhiko Iwahashi, Keitaro Nakagiri, Junya Shite
No abstract text is available yet for this article.
November 2017: Circulation. Heart Failure
https://www.readbyqxmd.com/read/29136224/reliable-identification-of-benign-clinical-course-in-aneurysmal-subarachnoid-hemorrhage-a-simple-and-qualitative-algorithm
#5
Yifei Duan, James Wright, Christina Wright, Berje Shammassian, Curtis Tatsuoka, Nicholas Bambakidis
BACKGROUND: A reliable method to specifically identify low vasospasm risk in aneurysmal subarachnoid hemorrhage (aSAH) patients has not been previously proposed. OBJECTIVE: To develop a clinical algorithm using admission aSAH clinical severity and subarachnoid blood distribution to identify patients at low risk of clinical vasospasm. METHODS: Clinical severities, admission noncontrasted head computerized tomography (CT) scan, and incidences of vasospasm among 291 aSAH patients treated at our institution were evaluated...
November 10, 2017: Neurosurgery
https://www.readbyqxmd.com/read/29125410/hemorrhage-associated-with-ventriculoperitoneal-shunt-placement-in-aneurysmal-subarachnoid-hemorrhage-patients-on-a-regimen-of-dual-antiplatelet-therapy-a-retrospective-analysis
#6
Joseph S Hudson, Yasunori Nagahama, Daichi Nakagawa, Robert M Starke, Brian J Dlouhy, James C Torner, Pascal Jabbour, Lauren Allan, Colin P Derdeyn, Jeremy D W Greenlee, David Hasan
OBJECTIVE Intracranial stenting and flow diversion require the use of dual antiplatelet therapy (DAPT) to prevent in-stent thrombosis. DAPT may significantly increase the risk of hemorrhagic complications in patients who require subsequent surgical interventions. In this study, the authors sought to investigate whether DAPT is a risk factor for hemorrhagic complications associated with ventriculoperitoneal (VP) shunt placement in patients with aneurysmal subarachnoid hemorrhage (aSAH). Moreover, the authors sought to compare VP shunt complication rates with respect to the shunt's location from the initial external ventricular drain (EVD) site...
November 10, 2017: Journal of Neurosurgery
https://www.readbyqxmd.com/read/29118801/trends-in-endovascular-treatment-of-aneurysmal-subarachnoid-hemorrhages
#7
Tapan Mehta, Neil Datta, Smit Patel, Kathan Mehta, Mohammed Hussain, Inaam Kureshi, Martin Ollenschleger, Amre Nouh
Introduction: Aneurysmal subarachnoid hemorrhage (aSAH) accounts for 5% of all strokes; 30-day mortality is as high as 40%. We sought to evaluate outcomes of aSAH patients treated 2004-2014 by endovascular therapy (EVT), to demonstrate associated trends, and to evaluate angioplasty use for aSAH-related cerebral vasospasm. Methods: The Nationwide Inpatient Sample (NIS) database 2004-2014 was used to derive a study cohort using ICD-9 codes. Survey procedures were used to adjust for stratified cluster design of NIS...
October 2017: Interventional Neurology
https://www.readbyqxmd.com/read/29099296/dual-antiplatelet-therapy-in-aneurysmal-subarachnoid-hemorrhage-association-with-reduced-risk-of-clinical-vasospasm-and-delayed-cerebral-ischemia
#8
Yasunori Nagahama, Lauren Allan, Daichi Nakagawa, Mario Zanaty, Robert M Starke, Nohra Chalouhi, Pascal Jabbour, Robert D Brown, Colin P Derdeyn, Enrique C Leira, Joseph Broderick, Marc Chimowitz, James C Torner, David Hasan
OBJECTIVE Clinical vasospasm and delayed cerebral ischemia (DCI) are devastating complications of aneurysmal subarachnoid hemorrhage (aSAH). Several theories involving platelet activation have been postulated as potential explanations of the development of clinical vasospasm and DCI. However, the effects of dual antiplatelet therapy (DAPT; aspirin and clopidogrel) on clinical vasospasm and DCI have not been previously investigated. The objective of this study was to evaluate the effects of DAPT on clinical vasospasm and DCI in aSAH patients...
November 3, 2017: Journal of Neurosurgery
https://www.readbyqxmd.com/read/29098719/aortic-root-replacement-in-a-patient-following-congenital-aortico-left-ventricular-tunnel-repair-in-childhood
#9
Jaclyn N Portelli Tremont, Amit Kalra, Christine Savarese, Leonard Y Lee
Congenital aortico-left ventricular tunnel requires surgical repair during childhood. Long-term surveillance is essential in these patients given the risk for aortic aneurysm development in adulthood. We describe an aortic root replacement for an aortic aneurysm five decades following the closure of an aortic-left ventricular tunnel.
November 3, 2017: Journal of Cardiac Surgery
https://www.readbyqxmd.com/read/29082864/fitness-to-drive-in-cardiovascular-disease
#10
Hermann H Klein, Udo Sechtem, Hans-Joachim Trappe
BACKGROUND: Medical students are taught little or nothing about the medical considerations related to the driving of motor vehicles. Physicians treating patients with cardiovascular disease need to acquire competence in traffic medicine in order to be able to advise them about their fitness to drive. METHODS: We present the current governmental regulations and recommendations concerning fitness to drive in patients with cardiovascular disease. We also review pertinent publications that were retrieved by a selective search in PubMed with the search terms "cardiovascular disease and traffic accidents" and "cardiovascular disease and traffic deaths" for the decade 2007-2016, as well as further publications collected by us individually...
October 13, 2017: Deutsches Ärzteblatt International
https://www.readbyqxmd.com/read/29073106/cardiovascular-homeostasis-dependence-on-micu2-a-regulatory-subunit-of-the-mitochondrial-calcium-uniporter
#11
Alexander G Bick, Hiroko Wakimoto, Kimberli J Kamer, Yasemin Sancak, Olga Goldberger, Anna Axelsson, Daniel M DeLaughter, Joshua M Gorham, Vamsi K Mootha, J G Seidman, Christine E Seidman
Comparative analyses of transcriptional profiles from humans and mice with cardiovascular pathologies revealed consistently elevated expression of MICU2, a regulatory subunit of the mitochondrial calcium uniporter complex. To determine if MICU2 expression was cardioprotective, we produced and characterized Micu2(-/-) mice. Mutant mice had left atrial enlargement and Micu2(-/-) cardiomyocytes had delayed sarcomere relaxation and cytosolic calcium reuptake kinetics, indicating diastolic dysfunction. RNA sequencing (RNA-seq) of Micu2(-/-) ventricular tissues revealed markedly reduced transcripts encoding the apelin receptor (Micu2(-/-) vs...
October 24, 2017: Proceedings of the National Academy of Sciences of the United States of America
https://www.readbyqxmd.com/read/29066242/estimating-risk-of-adverse-cardiac-event-after-vascular-surgery-using-currently-available-online-calculators
#12
Danielle A Moses, Lily E Johnston, Margaret C Tracci, William P Robinson, Kenneth J Cherry, John A Kern, Gilbert R Upchurch
BACKGROUND: The decision to proceed with vascular surgical interventions requires evaluation of cardiac risk. Recently, several online risk calculators were created to predict outcomes and to lead to a more informed conversation between surgeons and patients. The objective of this study was to compare and further validate these online calculators with actual adverse cardiac outcomes at a single institution. METHODS: All patients from January 2011 through December 2015 undergoing carotid endarterectomy (CEA), infrainguinal lower extremity bypass, open abdominal aortic aneurysm (AAA) repair, and endovascular aneurysm repair (EVAR) on the vascular surgical service were included using the Society for Vascular Surgery Vascular Quality Initiative database at our health system...
October 21, 2017: Journal of Vascular Surgery
https://www.readbyqxmd.com/read/29061453/prevention-of-the-rerupture-of-collateral-artery-aneurysms-on-the-ventricular-wall-by-early-surgical-revascularization-in-moyamoya-disease-report-of-two-cases-and-review-of-the-literature
#13
Fumiaki Kanamori, Syuntaro Takasu, Shinji Ota, Yukio Seki
BACKGROUND: Collateral artery aneurysms are a source of intracranial hemorrhage in moyamoya disease. Several reports have shown that surgical revascularization leads to the obliteration of collateral artery aneurysms. However, its effect on the prevention of rebleeding has not been established, and the optimal timing of the operation remains unclear. The purpose of the present study is to evaluate the effects of surgical revascularization and to investigate the optimal operation timing in patients with moyamoya disease who have ruptured collateral artery aneurysms on the ventricular wall...
October 20, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/29050825/neuroimaging-findings-in-infantile-pompe-patients-treated-with-enzyme-replacement-therapy
#14
Paul T McIntosh, Lisa D Hobson-Webb, Zoheb B Kazi, Sean N Prater, Suhrad G Banugaria, Stephanie Austin, Raymond Wang, David S Enterline, Donald P Frush, Priya S Kishnani
BACKGROUND: Recombinant human acid α-glucosidase (rhGAA) enzyme replacement therapy (ERT) has prolonged survival in infantile Pompe disease (IPD), but has unmasked central nervous system (CNS) changes. METHODS: Brain imaging, consisting of computed tomography (CT) and/or magnetic resonance imaging (MRI), was performed on 23 patients with IPD (17 CRIM-positive, 6 CRIM-negative) aged 2-38months. Most patients had baseline neuroimaging performed prior to the initiation of ERT...
October 13, 2017: Molecular Genetics and Metabolism
https://www.readbyqxmd.com/read/29049818/dor-procedure-for-pulmonary-atresia-with-intact-ventricular-septum-in-an-infant
#15
Yoonjin Kang, Jae Gun Kwak, Eung Rae Kim, Woong-Han Kim
Pulmonary atresia with intact ventricular septum and right ventricle-dependent coronary circulation confers a high risk for myocardial infarction and complications of ischaemia, including left ventricle aneurysms. We describe an infant with pulmonary atresia with intact ventricular septum and right ventricle-dependent coronary circulation and a left ventricle apical aneurysm who successfully underwent the Dor procedure and a subsequent Fontan operation. Surgery for postinfarction left ventricle aneurysm can be considered in infants...
September 2, 2017: Interactive Cardiovascular and Thoracic Surgery
https://www.readbyqxmd.com/read/29049790/sinus-of-valsalva-aneurysms-with-concomitant-aortic-insufficiency-how-should-the-aortic-valve-be-managed
#16
Yi Lin, Kanhua Yin, Yulin Wang, Changfa Guo, Ziwei Tian, Qiuchen Xie, Zhiqi Zhang, Chunsheng Wang
OBJECTIVES: Sinus of Valsalva aneurysms (SVAs) are rare and are often complicated by aortic insufficiency (AI). Treating AI is important for achieving good long-term results in patients with SVA. Here, we have summarized our experience with the surgical management of patients with SVA with concomitant AI. METHODS: Patients who were diagnosed with SVA and underwent surgical treatment between January 2008 and May 2016 were included. Clinical characteristics, including age, gender, SVA anatomy and concurrent anomalies, were analysed...
September 14, 2017: Interactive Cardiovascular and Thoracic Surgery
https://www.readbyqxmd.com/read/29035991/myocardial-perfusion-spect-and-cardiac-mr-correlative-imaging
#17
Ashley E Prosper, Patrick M Colletti
An institutional review board-approved retrospective review of 55 patients who received cardiac MRI within 1 year of myocardial SPECT was performed. Forty-nine demonstrated myocardial infarction by MRI. MRI and SPECT agreed in all but 1 case, where SPECT preceded MRI by 97 days. Three cases are presented here: 2 demonstrating congruent MRI and SPECT changes in a vascular distribution status post infarction and a third with a nonvascular pattern of abnormalities related to left ventricular aneurysm in cardiac sarcoidosis...
October 13, 2017: Clinical Nuclear Medicine
https://www.readbyqxmd.com/read/29033755/a-rare-case-of-submitral-left-ventricular-aneurysms
#18
Zara Wani, Meenaxi Sharma
No abstract text is available yet for this article.
October 2017: Saudi Journal of Anaesthesia
https://www.readbyqxmd.com/read/29033375/intraprocedural-arterial-perforation-during-neuroendovascular-therapy-preliminary-result-of-a-dual-trained-endovascular-neurosurgeon-in-the-neurosurgical-hybrid-operating-room
#19
Yuang-Seng Tsuei, Chih-Hsiang Liao, Chung-Hsin Lee, Yea-Jiuan Liang, Wen-Hsien Chen, Shun-Fa Yang
BACKGROUND: Intraprocedural arterial perforation (IPAP) is a potentially dismal complication of neuroendovascular therapy with high mortality and morbidity rates. The management of IPAP with the techniques described has been well established, but rescue results from the dual-trained endovascular neurosurgeon in the neurosurgical hybrid operating room (OR) are rarely reported. Here, we report five cases of successful rescue of IPAP in the neurosurgical hybrid OR and compare them with other series...
October 12, 2017: Journal of the Chinese Medical Association: JCMA
https://www.readbyqxmd.com/read/29029074/multimodality-imaging-evaluation-of-chagas-disease-an-expert-consensus-of-brazilian-cardiovascular-imaging-department-dic-and-the-european-association-of-cardiovascular-imaging-eacvi
#20
Maria Carmo P Nunes, Luigi Paolo Badano, J Antonio Marin-Neto, Thor Edvardsen, Covadonga Fernández-Golfín, Chiara Bucciarelli-Ducci, Bogdan A Popescu, Richard Underwood, Gilbert Habib, Jose Luis Zamorano, Roberto Magalhães Saraiva, Ester Cerdeira Sabino, Fernando A Botoni, Márcia Melo Barbosa, Marcio Vinicius L Barros, Eduardo Falqueto, Marcus Vinicius Simões, André Schmidt, Carlos Eduardo Rochitte, Manoel Otávio Costa Rocha, Antonio Luiz Pinho Ribeiro, Patrizio Lancellotti
Aims: To develop a document by Brazilian Cardiovascular Imaging Department (DIC) and the European Association of Cardiovascular Imaging (EACVI) to review and summarize the most recent evidences about the non-invasive assessment of patients with Chagas disease, with the intent to set up a framework for standardized cardiovascular imaging to assess cardiovascular morphologic and functional disturbances, as well as to guide the subsequent process of clinical decision-making. Methods and results: Chagas disease remains one of the most prevalent infectious diseases in Latin America, and has become a health problem in non-endemic countries...
September 25, 2017: European Heart Journal Cardiovascular Imaging
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