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https://www.readbyqxmd.com/read/28454484/effect-of-topical-application-of-hard-water-in-weakening-of-hair-in-men
#1
Waqas Muhammad
BACKGROUND: Hard water is thought to play a key role in weakening of hair (not Hair Loss) and breakage especially when travelling is involved. In our community, commonly men do the travelling and complain more about hair problem which is why only young male individuals were included in this study. MATERIALS AND METHODS: Water samples from different districts of KPK, Pakistan, were collected and their hardness values were estimated to find the water sample of maximum and minimum water hardness in order to know the maximum hardness hair would encounter in KPK, Pakistan...
September 30, 2016: JPMA. the Journal of the Pakistan Medical Association
https://www.readbyqxmd.com/read/28454479/in-situ-immobilization-on-the-silica-gel-surface-and-adsorption-capacity-of-poly-n-4-carboxyphenyl-methacrylamide-on-toxic-metal-ions
#2
Elina Yanovska, Irina Savchenko, Dariusz Sternik, Olga Kychkiruk, Lidiya Ol'khovik, Iana Buriachenko
In situ immobilization of poly[N-(4-carboxyphenyl)methacrylamide] has been performed on silica gel surface. Infrared (IR) and mass spectroscopies as well as thermogravimetry (TG) analysis have been used to elucidate the structure of immobilized polymer. An adsorption capacity of the synthesized composite towards Cu(II), Pb(II), Mn(II), Fe(III), Co(II), and Ni(II) ions has been estimated. Adsorption activity to microquantities of Pb(II), Cu(II), and Ni(II) in a neutral aqueous medium has been observed.
December 2017: Nanoscale Research Letters
https://www.readbyqxmd.com/read/28454385/neuroendocrine-differentiation-is-predictive-of-poor-survival-in-patients-with-stage-ii-colorectal-cancer
#3
Yue Liu, Jinjie He, Jinghong Xu, Jun Li, Yurong Jiao, Dikai Bei, Yeting Hu, Haiyan Chen, Qian Xiao, Kefeng Ding
The diagnosis of neuroendocrine differentiation (NED) is made primarily on the basis of ultrastructure and/or immunohistochemistry (IHC). Synaptophysin (Syn) and chromogranin A (CgA) are two important frequently used NED markers in colorectal cancer (CRC). The association between NED and the prognosis of stage II CRC remains controversial. Administration of adjuvant chemotherapy remains challenging for stage II CRC. Identification of reliable factors that improve the selection of patients with stage II CRC at high risk following surgery is of great importance...
April 2017: Oncology Letters
https://www.readbyqxmd.com/read/28454334/taxotere-induced-elevated-expression-of-il8-in-carcinoma-associated-fibroblasts-of-breast-invasive-ductal-cancer
#4
Yingliang Li, Guohua Rong, Hua Kang
Breast cancer is the most common malignant tumor in women worldwide, and accounts for an estimated 29% of new cases and 15% of cancer-associated mortalities each year. Invasive ductal carcinoma represents 70-80% of all breast cancer cases, which are responsible for the majority of breast cancer fatalities. Though great progress has been made in understanding the tumorigenesis and development of breast cancer, problems surrounding treatment persist. It was previously reported that carcinoma-associated fibroblasts (CAFs) may be closely associated with chemotherapy resistance...
March 2017: Oncology Letters
https://www.readbyqxmd.com/read/28454233/karyopherin-alpha-2-expression-is-a-novel-diagnostic-and-prognostic-factor-for-colorectal-cancer
#5
Lei Yu, Guiyu Wang, Qian Zhang, Li Gao, Rui Huang, Yinggang Chen, Qingchao Tang, Jin Liu, Chunjia Liu, Hongwei Wang, Xishan Wang
Colorectal cancer (CRC) is the fourth most common cancer and the second leading cause of cancer-associated mortality in Western countries. CRC treatment is dependent on the preoperative and postoperative condition of patients. At present, the prognostic value of conventional parameters for the estimation of patient prognosis is limited. The aim of the present study was to investigate the expression of karyopherin α2 (KPNA2) in cancerous and healthy colon tissues and to evaluate the prognostic factors for patients with primary CRC...
March 2017: Oncology Letters
https://www.readbyqxmd.com/read/28454230/a-subpopulation-of-cancer-stem-cells-identifies-radiographic-characteristics-in-glioblastoma
#6
Ja Eun Kim, Sung Kwon Kim, Jaekyung Shin, Young-Bem Se, Seung Hong Choi, Sung-Hye Park, Seung Ah Choi, Ji Yeoun Lee, Ji Hoon Phi, Kyu-Chang Wang, Chul-Kee Park, Seung-Ki Kim
Cancer stem cells (CSCs), defined by CD133 expression, harbor heterogeneous subpopulations of cells, including endothelial progenitor cells (EPCs). This study aimed to investigate whether a subpopulation of CSCs could affect the radiographic characteristics of glioblastoma. Tissue samples from 10 patients newly diagnosed with glioblastoma were selected according to the radiographic characteristics of their tumors. The patients were divided into two groups based on preoperative magnetic resonance imaging demonstrating contrast enhancement, necrosis and infiltrative patterns: the enhancement/necrosis group (E/N, n=5) and the non-enhancement/infiltration group (NE/I, n=5)...
March 2017: Oncology Letters
https://www.readbyqxmd.com/read/28454175/estimation-of-photonic-crystal-fiber-dispersion-by-means-of-supercontinuum-generation
#7
Julius Vengelis, Vygandas Jarutis, Valdas Sirutkaitis
We present a technique for photonic crystal fiber dispersion measurement. We demonstrate that investigating supercontinuum using cross-correlation frequency resolved optical gating (XFROG) technique can be used for quantitatively characterizing dispersion and observing orthogonal polarization modes in polarization maintaining photonic crystal fibers. In addition, an XFROG trace of supercontinuum generated in a polarization maintaining photonic crystal fiber reveals complex behavior of orthogonal polarization modes that is different in normal and anomalous dispersion regions of the photonic crystal fiber...
May 1, 2017: Optics Letters
https://www.readbyqxmd.com/read/28454128/2-3-%C3%AE-m-tm-sup-3-sup-ylf-laser-passively-q-switched-with-a-cr-sup-2-sup-znse-saturable-absorber
#8
Ferda Canbaz, Ismail Yorulmaz, Alphan Sennaroglu
We report, what is to our knowledge, the first passively Q-switched operation of a 2.3-μm Tm<sup>3+</sup>:YLF laser by using a Cr<sup>2+</sup>:ZnSe saturable absorber. In the experiments, a tunable Ti<sup>3+</sup>:sapphire laser was used to end pump the Tm<sup>3+</sup>:YLF gain medium inside an x cavity. A Cr<sup>2+</sup>:ZnSe saturable absorber was also included in the cavity to initiate passive Q switching. At all pump power levels above lasing threshold, passively Q-switched operation of the Tm<sup>3+</sup>:YLF laser could be obtained at 2309 nm with pulse durations and repetition frequencies in the ranges of 1...
May 1, 2017: Optics Letters
https://www.readbyqxmd.com/read/28454114/estimating-the-effects-of-transcription-factors-binding-and-histone-modifications-on-gene-expression-levels-in-human-cells
#9
Lu-Qiang Zhang, Qian-Zhong Li
Transcription factors and histone modifications are vital for the regulation of gene expression. Hence, to estimate the effects of transcription factors binding and histone modifications on gene expression, we construct a statistical model for the genome-wide 15 transcription factors binding data, 10 histone modifications profiles and DNase-I hypersensitivity data in three mammalian. Remarkably, our results show POLR2A and H3K36me3 can highly and consistently predict gene expression in three cell lines. And H3K4me3, H3K27me3 and H3K9ac are more reliable predictors than other histone modifications in human embryonic stem cells...
April 9, 2017: Oncotarget
https://www.readbyqxmd.com/read/28454095/association-between-psca-gene-polymorphisms-and-the-risk-of-cancer-an-updated-meta-analysis-and-trial-sequential-analysis
#10
Zhiqiang Qin, Jingyuan Tang, Xiao Li, Yajie Yu, Chuanjie Zhang, Peng Han, Ran Li, Xuping Jiang, Chengdi Yang, Wei Wang, Min Tang, Wei Zhang
Previous studies have investigated the relationships between PSCA rs2294008 C>T and rs2976392 G>A polymorphisms and cancer susceptibility. However, the available findings remained inconsistent and even controversial. Thus, the aim of this meta-analysis was performed to clarify such associations. The online databases PubMed, EMBASE and Web of Science searched for relevant studies, covering all the papers published until September 1st, 2016. Data were pooled by odds ratios (ORs) with 95% confidence intervals (CIs) to evaluate the strength of such associations...
April 10, 2017: Oncotarget
https://www.readbyqxmd.com/read/28454089/p-akt-as-a-potential-poor-prognostic-factor-for-gastric-cancer-a-systematic-review-and-meta-analysis
#11
REVIEW
Fang Cao, Cong Zhang, Wei Han, Xiao-Jiao Gao, Jun Ma, Yong-Wei Hu, Xing Gu, Hou-Zhong Ding, Li-Xia Zhu, Qin Liu
To understand the relationship between p-Akt expression and the prognosis of patients with gastric cancer, we searched six databases, Pubmed, EMBASE, Cochrane Library, CNKI, Wanfang and CBM for relevant articles in order to conduct this metaanalysis. The pooled hazard ratios and corresponding 95%CI of overall survival were calculated to evaluate the prognostic value of p-Akt expression in patients with gastric cancer. With 2261 patients combined from 13 available studies, the pooled HR showed a poor prognosis in patients with gastric cancer in the univariate analysis (HR=1...
April 10, 2017: Oncotarget
https://www.readbyqxmd.com/read/28454022/quantitative-analysis-of-adsorptive-interactions-of-ionic-and-neutral-pharmaceuticals-and-other-chemicals-with-the-surface-of-escherichia-coli-cells-in-aquatic-environment
#12
Chul-Woong Cho, Jeong-Soo Park, Yufeng Zhao, Yeoung-Sang Yun
Since Escherichia coli is ubiquitous in nature and has been applied to biological, chemical, and environmental processes, molecular-level understanding of adsorptive interactions between chemicals and the bacterial surface is of great importance. To characterise the adsorption properties of the surface of E. coli cells in aquatic environment, the binding affinities (log Kd) of calibration compounds were experimentally measured, and then based on the values and numerically well-defined molecular interaction forces, i...
April 25, 2017: Environmental Pollution
https://www.readbyqxmd.com/read/28454017/the-nexus-between-urbanization-and-pm2-5-related-mortality-in-china
#13
Miaomiao Liu, Yining Huang, Zhou Jin, Zongwei Ma, Xingyu Liu, Bing Zhang, Yang Liu, Yang Yu, Jinnan Wang, Jun Bi, Patrick L Kinney
The launch of China's new national urbanization plan, coupled with increasing concerns about air pollution, calls for better understandings of the nexus between urbanization and the air pollution-related health. Based on refined estimates of PM2.5 related mortality in China, we developed an Urbanization-Excess Deaths Elasticity (U-EDE) indicator to measure the marginal PM2.5 related mortality caused by urbanization. We then applied statistical models to estimate U-EDE and examined the modification effects of income on U-EDE...
April 25, 2017: Environmental Pollution
https://www.readbyqxmd.com/read/28453972/exposure-to-ambient-pm2-5-associated-with-overall-and-domain-specific-disability-among-adults-in-six-low-and-middle-income-countries
#14
Hualiang Lin, Yanfei Guo, Yang Zheng, Xing Zhao, Zheng Cao, Steven E Rigdon, Hong Xian, Xing Li, Tao Liu, Jianpeng Xiao, Weilin Zeng, Nancy L Weaver, ZhengminMin Qian, Wenjun Ma, Fan Wu
BACKGROUND: Exposure to particulate matter pollution is associated with various cardiopulmonary diseases, which are closely related with disability. The direct relationship between air pollution and disability, however, has not been fully explored. METHODS: We used data from 45,625 participants in the Study on global AGEing and adult health in six low- and middle-income countries. The 12-item version of the World Health Organization Disability Assessment Schedule (WHODAS 2...
April 25, 2017: Environment International
https://www.readbyqxmd.com/read/28453958/the-novel-technique-of-post-hysterectomy-vaginal-vault-prolapse-repair-apical-sling-and-neocervix-formation
#15
Dmitry Shkarupa, Nikita Kubin, Ekaterina Shapovalova, Anastasiya Zaytseva, Alexey Pisarev, Olga Staroseltseva
OBJECTIVE: We primarily aimed to evaluate the effectiveness of the novel technique: bilateral sacrospinous fixation by monofilament polypropylene apical sling combined with "neocervix" formation in surgical treatment of post - hysterectomy vaginal vault prolapse. The secondary objective was to estimate the impact of the surgery on voiding function and quality of life. STUDY DESIGN: This prospective study involved 61 women suffering from post-hysterectomy prolapse...
April 23, 2017: European Journal of Obstetrics, Gynecology, and Reproductive Biology
https://www.readbyqxmd.com/read/28453937/impact-of-dielectric-constant-on-the-singlet-triplet-gap-in-thermally-activated-delayed-fluorescence-tadf-materials
#16
Haitao Sun, Zhubin Hu, Cheng Zhong, XianKai Chen, Zhenrong Sun, Jean-Luc Bredas
Thermally activated delayed fluorescence (TADF) relies on the presence of a very small energy gap, ΔEST, between the lowest singlet and triplet excited states. ΔEST is thus a key factor in the molecular design of more efficient materials. However, its accurate theoretical estimation remains challenging, especially in the solid state due to the influence of polarization effects. In this Letter, we have quantitatively studied ΔEST as a function of dielectric constant, ε, for four representative organic molecules using the methodology we recently proposed at the Tamm-Dancoff Approximation ωB97X level of theory, where the range-separation parameter ω is optimized with the polarizable continuum model (PCM)...
April 28, 2017: Journal of Physical Chemistry Letters
https://www.readbyqxmd.com/read/28453898/electrophysiological-effects-of-anthracyclines-in-adult-survivors-of-pediatric-malignancy
#17
Timothy M Markman, Kathryn Ruble, David Loeb, Allen Chen, Yiyi Zhang, Gary S Beasley, W Reid Thompson, Saman Nazarian
BACKGROUND: Anthracycline use is limited by cardiotoxicity, including arrhythmias and left ventricular (LV) dysfunction. We aim to characterize the association between electrophysiological changes and LV dysfunction. METHODS: A retrospective chart review was conducted, including all 147 pediatric cancer survivors at our institution over 18 years of age and treated with an anthracycline. One hundred thirty-four patients who had at least one electrocardiogram (ECG) and echocardiogram were analyzed...
April 28, 2017: Pediatric Blood & Cancer
https://www.readbyqxmd.com/read/28453897/clinical-outcome-of-childhood-chronic-immune-thrombocytopenia-a-38-year-experience-from-a-single-tertiary-center-in-thailand
#18
Thirachit Chotsampancharoen, Pornpun Sripornsawan, Sarapee Duangchoo, Malai Wongchanchailert, Edward McNeil
BACKGROUND: There is limited information on long-term follow-up and prognostic factors for remission among children diagnosed with chronic immune thrombocytopenia (ITP). The aim of this study was to determine clinical outcomes and factors influencing remission in childhood chronic ITP. STUDY DESIGN: The hospital records of children aged 0-15 years diagnosed with chronic ITP were retrospectively reviewed. Kaplan-Meier curves were fit to estimate the median time to complete remission with 95% confidence intervals (CIs)...
April 28, 2017: Pediatric Blood & Cancer
https://www.readbyqxmd.com/read/28453881/effect-of-an-acute-exercise-bout-on-immediate-post-exercise-irisin-concentration-in-adults-a-meta-analysis
#19
REVIEW
Jill Fox, Brittany V Rioux, Eric D B Goulet, Neil M Johanssen, Damon L Swift, Danielle R Bouchard, Hal Loewen, Martin Sénéchal
BACKGROUND: Irisin is a recently discovered myokine that increases adipocyte metabolism, induces further "browning" of white adipose tissue, and enhance glucose metabolism. No study has ever determined how an acute bout of exercise impacts immediate post-exercise irisin concentration using a meta-analytic approach. OBJECTIVE: To determine the impact of an acute bout of exercise on the magnitude of post-exercise irisin concentration in adults using meta-analytic procedures...
April 28, 2017: Scandinavian Journal of Medicine & Science in Sports
https://www.readbyqxmd.com/read/28453868/combined-aerobic-and-resistance-training-decreases-inflammation-markers-in-healthy-men
#20
J K Ihalainen, M Schumann, D Eklund, M Hämäläinen, E Moilanen, G Paulsen, K Häkkinen, A A Mero
BACKGROUND AND AIMS: Our primary aim was to study the effects of 24 weeks of combined aerobic and resistance training performed on the same day or on different days on inflammation markers. METHODS AND RESULTS: Physically active, healthy young men were randomly divided into three groups that performed: aerobic and resistance training consecutively in the same training session (SS) 2-3 d·wk(-1) or on alternating days (AD) 4-6 d·wk(-1) as well as control (C). The total training volume was matched in the training groups...
April 28, 2017: Scandinavian Journal of Medicine & Science in Sports
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