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Intravenous lidocaine

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https://www.readbyqxmd.com/read/29741660/intravenous-lidocaine-provides-similar-analgesia-to-intravenous-morphine-for-undifferentiated-severe-pain-in-the-emergency-department-a-pilot-unblinded-randomized-controlled-trial
#1
Eben J Clattenburg, Anthony Nguyen, Tina Yoo, Stefan Flores, Christian Hailozian, Derex Louie, Andrew A Herring
Objectives: We compared the analgesic effects of intravenous (IV) lidocaine and IV morphine for the treatment of severe pain in the emergency department (ED). Methods: This was a pilot, unblinded randomized controlled study comparing the efficacy of IV lidocaine vs IV morphine for patients aged ≥18 years with severe pain (numerical rating scale [NRS] ≥ 7). Participants were randomized to receive IV lidocaine (75 mg if <50 kg, 100 mg if 50-100 kg, and 150 mg if >100 kg) over 10 minutes, followed by a 50-minute IV lidocaine infusion of the same dose or provider-chosen dose of morphine...
May 7, 2018: Pain Medicine: the Official Journal of the American Academy of Pain Medicine
https://www.readbyqxmd.com/read/29739540/intravenous-lidocaine
#2
REVIEW
Jean-Pierre Estebe
Lidocaine has analgesic effect and antihyperalgesic and anti-inflammatory properties, which enable its use as a general anesthetic adjuvant. Lidocaine can reduce nociception and/or cardiovascular responses to surgical stress, postoperative pain, and/or analgesic requirements. However, its mechanisms of action remain unclear, despite its different known properties. Although the exact mechanism of action remains uncertain, initial bolus followed by a continuous lidocaine infusion has clear analgesic benefits...
December 2017: Best Practice & Research. Clinical Anaesthesiology
https://www.readbyqxmd.com/read/29733751/sacrospinous-ligament-fixation-under-local-anesthesia-in-elderly-patients-at-high-risk-of-general-anesthesia
#3
Mehmet Baki Senturk, Ozan Doğan
INTRODUCTION AND HYPOTHESIS: Sacrospinous ligament fixation(SSLF) is a commonly used surgical procedure in pelvic organ prolapse due to high treatment success rates. Many intraoperative and postoperative anesthesia-related obstacles may be encountered by the elderly population. Local anesthesia alone or with intravenous sedation may provide simple, cheap, and safe anesthesia. For elderly patients at high risk for general anesthesia according to the American Society of Anesthesiologists(ASA), it is better to operate through the vaginal route under local anesthesia...
May 7, 2018: Journal of Investigative Surgery: the Official Journal of the Academy of Surgical Research
https://www.readbyqxmd.com/read/29725828/comparison-of-effect-of-dexmedetomidine-and-lidocaine-on-intracranial-and-systemic-hemodynamic-response-to-chest-physiotherapy-and-tracheal-suctioning-in-patients-with-severe-traumatic-brain-injury
#4
Shalendra Singh, Rajendra Singh Chouhan, Ashish Bindra, Nayani Radhakrishna
PURPOSE: Chest physiotherapy and tracheal suction cause sympathetic stimulation and increase heart rate (HR), mean arterial pressure (MAP) and intracranial pressure (ICP) which may have deleterious effect in the head injured. We planned to compare the effect of intravenous dexmedetomidine and lidocaine on intracerebral and systemic hemodynamic response to chest physiotherapy (CP) and tracheal suctioning (TS) in patients with severe traumatic brain injury (sTBI). METHODS: Prospective, randomized study in patients with sTBI, 18-60 years of age, undergoing mechanical ventilation and intraparenchymal ICP monitoring...
May 3, 2018: Journal of Anesthesia
https://www.readbyqxmd.com/read/29724305/-effects-of-continuous-intravenous-intraoperative-lidocaine-infusion-on-opioids-consumption-and-postoperative-recovery-in-patients-undergoing-video-assisted-thoracoscopic-lobectomy
#5
Zi Jia Liu, Liang Yan Zhang, Xu Guang Zheng, Le Shen, Kai Cheng Song, Jie Yi, Yu Guang Huang
Objective To investigate whether continuous intravenous intraoperative lidocaine infusion can reduce the opioids dosage and improve postoperative recovery in patients undergoing video-assisted thoracoscopic(VATS) lobectomy. Methods Totally 60 patients undergoing VATS lobectomy were enrolled in this single-center randomized controlled study.The patients were equally randomized into lidocaine continuous pumping group(lidocaine group) and control group by computer-based random numbers.The patients had double-lumen catheter intubation,and total intravenous anesthesia was administrated intraoperatively...
April 28, 2018: Zhongguo Yi Xue Ke Xue Yuan Xue Bao. Acta Academiae Medicinae Sinicae
https://www.readbyqxmd.com/read/29720816/short-lasting-unilateral-neuralgiform-headache-attacks
#6
REVIEW
Andrew Levy, Manjit S Matharu
Short-lasting unilateral neuralgiform headache attacks (SUNHA) is characterized by strictly unilateral trigeminal distribution pain that occurs in association with ipsilateral cranial autonomic features. There are two subtypes: short-lasting unilateral neuralgiform headache attacks with conjunctival injection and tearing (SUNCT) and short-lasting unilateral neuralgiform headache attacks with cranial autonomic symptoms (SUNA). These disorders are rare but highly disabling. The management of SUNHA can be challenging...
April 2018: Annals of Indian Academy of Neurology
https://www.readbyqxmd.com/read/29698250/the-analgesic-and-emotional-response-to-intravenous-lidocaine-infusion-in-the-treatment-of-postherpetic-neuralgia-a-randomized-double-blinded-placebo-controlled-study
#7
Hui Liu, Fan Lu, Dan Zhou, Yan Yin, Jun Li, BangXiang Yang, Li Song, Ling Ye, Hong Xiao
OBJECTIVES: This study evaluates the analgesic efficacy and emotional response of intravenous lidocaine infusion compared with placebo in patients with postherpetic neuralgia(PHN). METHODS: In this randomized, double-blinded study, patients with PHN received 5▒mg/kg intravenous lidocaine infusion or placebo. The primary outcome was pain relief measured by Visual Analogue Scale (VAS), Von Frey and area of allodynia. Moreover, emotional status of anxiety and depression were evaluated by Self-Rating Anxiety Scale (SAS) and Self-Rating Depression Scale (SDS)...
April 25, 2018: Clinical Journal of Pain
https://www.readbyqxmd.com/read/29696122/comparison-of-magnesium-sulfate-and-tramadol-as-an-adjuvant-to-intravenous-regional-anesthesia-for-upper-extremity-surgeries
#8
Mohammad Ali Sahmeddini, Mohammad Bagher Khosravi, Masoome Seyedi, Zahra Hematfar, Sedighe Abbasi, Arash Farbood
Background: Intravenous Regional Anesthesia (IVRA) is a simple efficient method for providing regional anesthesia of the limbs. However, it has some limitations such as lack of postoperative analgesia. Objectives: This study aimed to compare the analgesic effects of magnesium sulfate and tramadol when added to lidocaine used for IVRA in upper limb surgery. Methods: In this double - blind randomized clinical trial, 69 patients who underwent elective upper limb surgery with IVRA were randomly allocated into 3 groups...
December 2017: Anesthesiology and Pain Medicine
https://www.readbyqxmd.com/read/29695926/pre-emptive-multimodal-analgesia-with-tramadol-and-ketamine-lidocaine-infusion-for-suppression-of-central-sensitization-in-a-dog-model-of-ovariohysterectomy
#9
Ubedullah Kaka, Nor-Alimah Rahman, Adamu Abdul Abubakar, Yong Meng Goh, Sharida Fakurazi, Mohamed Ariff Omar, Hui Cheng Chen
Objectives: The effects of pre-emptive infusion of ketamine-lidocaine with tramadol on the suppression of central sensitization were investigated in a dog ovariohysterectomy model. Patients and methods: Twelve dogs were randomly assigned to two groups: ketamine-lidocaine-tramadol (KLT) and tramadol (T) groups. Both groups received intravenous tramadol 4 mg/kg body weight as premedication. Immediately after induction, the KLT group received ketamine and lidocaine at 0...
2018: Journal of Pain Research
https://www.readbyqxmd.com/read/29694467/continuous-dentoalveolar-neuropathic-pain-response-to-repeated-intravenous-ketamine-infusions-a-case-report
#10
Isabel Moreno-Hay, John Lindroth
This article describes a case of continuous dentoalveolar neuropathic pain in which relief was obtained following repeated administration of intravenous infusions of a subanesthetic dose of ketamine. A 50-year-old female presented in 2006 with a 1-year history of constant sharp pain in the gingiva surrounding the maxillary left second premolar and second molar rated as 10/10 on a pain intensity scale. After multiple systemic medications failed to adequately manage the patient's pain, partial pain reduction was obtained (4/10) with daily use of methadone 50 mg in combination with application of a topical compound including lidocaine, amitriptyline, and carbamazepine to the affected area as needed...
April 2018: Journal of Oral & Facial Pain and Headache
https://www.readbyqxmd.com/read/29629201/anesthesia-and-fast-track-in-video-assisted-thoracic-surgery-vats-from-evidence-to-practice
#11
REVIEW
Marzia Umari, Stefano Falini, Matteo Segat, Michele Zuliani, Marco Crisman, Lucia Comuzzi, Francesco Pagos, Stefano Lovadina, Umberto Lucangelo
In thoracic surgery, the introduction of video-assisted thoracoscopic techniques has allowed the development of fast-track protocols, with shorter hospital lengths of stay and improved outcomes. The perioperative management needs to be optimized accordingly, with the goal of reducing postoperative complications and speeding recovery times. Premedication performed in the operative room should be wisely administered because often linked to late discharge from the post-anesthesia care unit (PACU). Inhalatory anesthesia, when possible, should be preferred based on protective effects on postoperative lung inflammation...
March 2018: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/29628664/7-5-nacl-resuscitation-leads-to-abnormal-clot-fibrinolysis-after-severe-hemorrhagic-shock-and-its-correction-with-7-5-nacl-adenosine-lidocaine-and-mg-2
#12
Hayley Louise Letson, Geoffrey Phillip Dobson
Background: Hyperfibrinolysis is a common complication of hemorrhagic shock. Our aim was to examine the effect of small-volume 7.5% NaCl adenosine, lidocaine, and Mg2+ (ALM) on fibrinolysis in the rat model of hemorrhagic shock. Methods: Rats were anesthetized and randomly assigned to one of four groups: (1) baseline, (2) shock, (3) 7.5% NaCl controls, and (4) 7.5% NaCl ALM. Animals were bled for 20 min (42% blood loss) and left in shock for 60 min before resuscitation with 0...
January 2018: Journal of Emergencies, Trauma, and Shock
https://www.readbyqxmd.com/read/29627919/acquired-methemoglobinemia-associated-with-topical-lidocaine-administration-a-case-report
#13
Hawkins C Gay, Ansel Philip Amaral
A 55-year-old male was admitted to the hospital with pneumonia. During an intubation procedure, the patient received an application of endobronchial lidocaine (4% gel). Within 2 h of intubation, the patient developed worsening hypoxia, and investigation of arterial blood gasses revealed a pH of 7.21, carbon dioxide partial pressure (PaCO2 ) of 3.3 kPa, oxygen partial pressure (PaO2 ) of 55.1 kPa, and measured oxygen saturation of 49%. Co-oximetry of this sample returned a methemoglobin level of 53%. Intravenous methylthioninium chloride (1% solution at 1 mg/kg) was delivered, and subsequent arterial blood gasses, at 30 min and 1 h post administration, showed methemoglobin levels of 12 and 9%, respectively, with return of oxygen saturation to > 90%...
April 7, 2018: Drug Safety—Case Reports
https://www.readbyqxmd.com/read/29627201/perioperative-analgesic-effects-of-an-ultrasound-guided-transversus-abdominis-plane-block-with-a-mixture-of-bupivacaine-and-lidocaine-in-cats-undergoing-ovariectomy
#14
Despoina Skouropoulou, Luca Lacitignola, Paola Centonze, Angela Simone, Alberto M Crovace, Francesco Staffieri
OBJECTIVE: To evaluate the perioperative analgesic effects of a transversus abdominis plane (TAP) block with a mixture of lidocaine and bupivacaine administered to cats undergoing ovariectomy. STUDY DESIGN: Controlled, randomized, prospective, blinded clinical study. ANIMALS: A group of 20 healthy cats. METHODS: Robenacoxib (2 mg kg-1 ) was administered subcutaneously 0.5 hour before intramuscular (IM) administration of ketamine (5 mg kg-1 ), methadone (0...
May 2018: Veterinary Anaesthesia and Analgesia
https://www.readbyqxmd.com/read/29606730/effect-of-different-analgesic-techniques-on-hemodynamic-variables-recorded-with-an-esophageal-doppler-monitor-during-ovariohysterectomy-in-dogs
#15
Ignacio Sández, María Soto, Daniel Torralbo, Eva Rioja
This study compared the efficacy of intravenous (IV) fentanyl and ketamine with lumbosacral epidural lidocaine in dogs undergoing ovariohysterectomy. Dogs with esophageal Doppler monitoring ( n = 112) were included in this retrospective study. All dogs were premedicated with dexmedetomidine and methadone, induced with IV propofol or alfaxalone and maintained using isoflurane and IV fentanyl, IV ketamine, or epidural lidocaine. Heart rate (HR), mean arterial pressure (MAP), expired fraction of isoflurane (ETIso), stroke distance (SD), minute distance (MD), peak velocity (PV) and mean acceleration (MA) were recorded before and after ligation of the ovarian pedicle (OvP)...
April 2018: Canadian Veterinary Journal. la Revue Vétérinaire Canadienne
https://www.readbyqxmd.com/read/29605659/interscalene-brachial-plexus-bolus-block-versus-patient-controlled-interscalene-indwelling-catheter-analgesia-for-the-first-48-hours-after-arthroscopic-rotator-cuff-repair
#16
Jong-Ho Kim, Hyun Jung Koh, Dong Kyu Kim, Hyo-Jin Lee, Ki-Hyun Kwon, Kwang-Yeol Lee, Yang-Soo Kim
BACKGROUND: We sought to compare the efficacy of interscalene brachial plexus bolus blockade (IBPBB) and patient-controlled interscalene indwelling catheter analgesia (PCIA) for postoperative pain management within 48 hours postoperatively in patients undergoing arthroscopic rotator cuff repairs (ARCR). METHODS: Patients undergoing ARCR were randomized into 3 groups by postoperative analgesia method. The IBPBB group received a mixed solution of 16 mL of 0.75% ropivacaine and 4 mL of 2% lidocaine as a bolus postoperatively...
March 29, 2018: Journal of Shoulder and Elbow Surgery
https://www.readbyqxmd.com/read/29595671/effect-of-intravenous-lidocaine-infusion-on-long-term-postoperative-pain-after-spinal-fusion-surgery
#17
Abdelrady Ibrahim, Mohamed Aly, Waleed Farrag
BACKGROUND: Intravenous lidocaine infusion is known to reduce postoperative pain for days or weeks beyond the infusion time, and plasma half-life in several types of surgical procedures. OBJECTIVES: To evaluate the effect of intravenous (IV) lidocaine infusion on long term postoperative pain intensity for 3 months in patients undergoing spinal fusion surgery. STUDY DESIGN: Prospective randomized, double-blinded study. SETTING: Assiut University Hospital, Assiut, Egypt...
March 2018: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29570151/incidence-and-risk-factors-for-chronic-postoperative-opioid-use-after-major-spine-surgery-a-cross-sectional-study-with-longitudinal-outcome
#18
Lauren K Dunn, Sandeep Yerra, Shenghao Fang, Mark F Hanak, Maren K Leibowitz, Siny Tsang, Marcel E Durieux, Edward C Nemergut, Bhiken I Naik
BACKGROUND: Chronic opioid use is a significant public health concern. Surgery is a risk factor for developing chronic opioid use. Patients undergoing major spine surgery frequently are prescribed opioids preoperatively and may be at risk for chronic opioid use postoperatively. The aim of this study was to investigate the incidence of and perioperative risk factors associated with chronic opioid use after major spine surgery. METHODS: The records of patients who underwent elective major spine surgery at the University of Virginia between March 2011 and February 2016 were retrospectively reviewed...
March 21, 2018: Anesthesia and Analgesia
https://www.readbyqxmd.com/read/29570108/intra-operative-lidocaine-in-the-prevention-of-vomiting-after-elective-tonsillectomy-in-children-a-randomised-controlled-trial
#19
Ghislaine C Echevarría, Fernando R Altermatt, Sebastian Paredes, Valentina Puga, Hernán Auad, Ana M Veloso, María F Elgueta
BACKGROUND: Postoperative vomiting (POV) is a frequent complication of tonsillectomy in children. In adult patients undergoing abdominal surgeries, the use of intravenous lidocaine infusion can prevent POV. OBJECTIVE: To evaluate the anti-emetic effect of an intravenous lidocaine infusion used as an adjuvant to general anaesthesia, in children undergoing elective ear, nose and throat surgery. DESIGN: Double-blind, randomised, controlled study...
May 2018: European Journal of Anaesthesiology
https://www.readbyqxmd.com/read/29558860/pregnant-sheep-develop-hypoxaemia-during-short-term-anaesthesia-for-caesarean-delivery
#20
Gabrielle C Musk, Matthew W Kemp
Short-term anaesthesia of the pregnant ewe may be required for caesarean delivery of a preterm foetus within a research protocol. The aim of this study was to evaluate and compare the acid-base and haematological status of the ewe and foetus at the time of surgical delivery by collecting maternal and foetal arterial blood samples. Fifteen date-mated singleton-pregnant merino cross ewes at 122.0 (±0.5) days of gestation were anaesthetised with a combination of midazolam (0.5 mg/kg) and ketamine (10 mg/kg) by intravenous injection...
January 1, 2018: Laboratory Animals
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