Sébastien Fritz, Chris Hoze, Emmanuelle Rebours, Anne Barbat, Méline Bizard, Amanda Chamberlain, Clémentine Escouflaire, Christy Vander Jagt, Mekki Boussaha, Cécile Grohs, Aurélie Allais-Bonnet, Maëlle Philippe, Amélie Vallée, Yves Amigues, Benjamin J Hayes, Didier Boichard, Aurélien Capitan
Researching depletions in homozygous genotypes for specific haplotypes among the large cohorts of animals genotyped for genomic selection is a very efficient strategy to map recessive lethal mutations. In this study, by analyzing real or imputed Illumina BovineSNP50 (Illumina Inc., San Diego, CA) genotypes from more than 250,000 Holstein animals, we identified a new locus called HH6 showing significant negative effects on conception rate and nonreturn rate at 56 d in at-risk versus control mating. We fine-mapped this locus in a 1...
April 18, 2018: Journal of Dairy Science