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https://www.readbyqxmd.com/read/28813087/validation-of-the-expression-and-emotion-scale-for-children-with-attention-deficit-hyperactivity-disorder-into-brazilian-portuguese
#1
Margarete Andreozzi Vaz Pereira Simon, Umbertina Conti Reed, Brigette Vaughan, Valdecir Antonio Simon, Erasmo Barbante Casella
Objective: To validate the parent-rated Expression and Emotion Scale for Children (EESC) for patients with attention-deficit/hyperactivity disorder (ADHD). Methods: The EESC was applied to parents of children with and without ADHD. The children were divided into age groups: Group A, between six and eight years old; Group B, between nine and 11 years old; and Group C, between 12 and 15 years old. The validation was carried out according to the steps proposed by Guillemin et al...
August 2017: Arquivos de Neuro-psiquiatria
https://www.readbyqxmd.com/read/28813082/middle-cerebral-artery-aneurysms-aneurysm-angiographic-morphology-and-its-relation-to-pre-operative-and-intra-operative-rupture
#2
Iracema Araújo Estevão, Bruno Camporeze, Antonio Santos de Araujo, Breno Nery, Ápio Claudio Martins Antunes, Timothy R Smith, Paulo Henrique Pires de Aguiar
Objective: Correlate the middle cerebral artery bifurcation aneurysm morphology with the pre-operative and intra-operative risk of rupture. Methods: Forty patients with 46 middle cerebral artery bifurcation aneurysms were treated microsurgically by the same surgeon. Aneurysms were classified according to shape and the Fisher test was applied to analyze the effect of morphology on the pre-operative and intra-operative rupture. Results: Pre-operative and intra-operative ruptures were observed in 8/46 patients (17...
August 2017: Arquivos de Neuro-psiquiatria
https://www.readbyqxmd.com/read/28813071/content-validation-clarity-relevance-reliability-and-internal-consistency-of-enunciative-signs-of-language-acquisition
#3
Anelise Henrich Crestani, Anaelena Bragança de Moraes, Ana Paula Ramos de Souza
Purpose: To analyze the results of the validation of building enunciative signs of language acquisition for children aged 3 to 12 months. Methods: The signs were built based on mechanisms of language acquisition in an enunciative perspective and on clinical experience with language disorders. The signs were submitted to judgment of clarity and relevance by a sample of six experts, doctors in linguistic in with knowledge of psycholinguistics and language clinic. In the validation of reliability, two judges/evaluators helped to implement the instruments in videos of 20% of the total sample of mother-infant dyads using the inter-evaluator method...
August 10, 2017: CoDAS
https://www.readbyqxmd.com/read/28813068/cultural-adaptation-of-the-short-self-regulation-questionnaire-suggestions-for-the-speech-area
#4
Anna Alice Almeida, Mara Behlau
Purpose: To present the translated and linguistic and culturally adapted version of the Short self-regulation Questionnaire (SSRQ) for the Brazilian Portuguese and to check its applicability to patients with dysphonia. Methods: The SSRQ is a tool used to evaluate the ability to self-regulate behavior; it has 31 items and generates three scores: total index of individual self-regulation capacity and partial scores for goal setting and impulse control. Each item should be scored by means of a Likert-type 5-point scale; the total score ranges from 29 to 145 points...
August 14, 2017: CoDAS
https://www.readbyqxmd.com/read/28813014/antibacterial-properties-of-nonwoven-wound-dressings-coated-with-manuka-honey-or-methylglyoxal
#5
Sophie E L Bulman, Giuseppe Tronci, Parikshit Goswami, Chris Carr, Stephen J Russell
Manuka honey (MH) is used as an antibacterial agent in bioactive wound dressings via direct impregnation onto a suitable substrate. MH provides unique antibacterial activity when compared with conventional honeys, owing partly to one of its constituents, methylglyoxal (MGO). Aiming to investigate an antibiotic-free antimicrobial strategy, we studied the antibacterial activity of both MH and MGO (at equivalent MGO concentrations) when applied as a physical coating to a nonwoven fabric wound dressing. When physically coated on to a cellulosic hydroentangled nonwoven fabric, it was found that concentrations of 0...
August 16, 2017: Materials
https://www.readbyqxmd.com/read/28813011/insights-into-the-effect-of-the-g245s-single-point-mutation-on-the-structure-of-p53-and-the-binding-of-the-protein-to-dna
#6
Marco Gaetano Lepre, Sara Ibrahim Omar, Gianvito Grasso, Umberto Morbiducci, Marco Agostino Deriu, Jack A Tuszynski
The transcription factor p53 is a potent tumor suppressor dubbed as the "guardian of the genome" because of its ability to orchestrate protective biological outputs in response to a variety of oncogenic stresses. Mutation and thus inactivation of p53 can be found in 50% of human tumors. The majority are missense mutations located in the DNA binding region. Among them, G245S is known to be a structural hotspot mutation. To understand the behaviors and differences between the wild-type and mutant, both a dimer of the wild type p53 (wt-p53) and its G245S mutant (G245S-mp53), complexed with DNA, were simulated using molecular dynamics for more than 1 μs...
August 16, 2017: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
https://www.readbyqxmd.com/read/28813000/an-ameliorated-prediction-of-drug-target-interactions-based-on-multi-scale-discrete-wavelet-transform-and-network-features
#7
Cong Shen, Yijie Ding, Jijun Tang, Xinying Xu, Fei Guo
The prediction of drug-target interactions (DTIs) via computational technology plays a crucial role in reducing the experimental cost. A variety of state-of-the-art methods have been proposed to improve the accuracy of DTI predictions. In this paper, we propose a kind of drug-target interactions predictor adopting multi-scale discrete wavelet transform and network features (named as DAWN) in order to solve the DTIs prediction problem. We encode the drug molecule by a substructure fingerprint with a dictionary of substructure patterns...
August 16, 2017: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/28812999/synthesis-and-evaluation-of-a-sodium-alginate-4-aminosalicylic-acid-based-microporous-hydrogel-for-potential-viscosupplementation-for-joint-injuries-and-arthritis-induced-conditions
#8
Dharmesh R Chejara, Mostafa Mabrouk, Pradeep Kumar, Yahya E Choonara, Pierre P D Kondiah, Ravindra V Badhe, Lisa C du Toit, Divya Bijukumar, Viness Pillay
A microporous hydrogel was developed using sodium alginate (alg) and 4-aminosalicylic acid (4-ASA). The synthesized hydrogel was characterized using various analytical techniques such as Fourier transform infrared spectroscopy (FTIR), Carbon-13 nuclear magnetic resonance ((13)C-NMR), X-ray powder diffraction (XRD), scanning electron microscopy (SEM), and differential scanning calorimetry (DSC). Additonal carboxyl and hydroxyl functional groups of 4-ASA provided significant lubrication and stress-triggered sol-gel transition to the conjugated hydrogel...
August 16, 2017: Marine Drugs
https://www.readbyqxmd.com/read/28812995/optimizing-waveform-maximum-determination-for-specular-point-tracking-in-airborne-gnss-r
#9
Erwan Motte, Mehrez Zribi
Airborne GNSS-R campaigns are crucial to the understanding of signal interactions with the Earth's surface. As a consequence of the specific geometric configurations arising during measurements from aircraft, the reflected signals can be difficult to interpret under certain conditions like over strongly attenuating media such as forests, or when the reflected signal is contaminated by the direct signal. For these reasons, there are many cases where the reflectivity is overestimated, or a portion of the dataset has to be flagged as unusable...
August 16, 2017: Sensors
https://www.readbyqxmd.com/read/28812983/a-microfluidic-platform-for-modeling-metastatic-cancer-cell-matrix-invasion
#10
Laura Blaha, Chentian Zhang, Mario Cabodi, Joyce Y Wong
Invasion of the extracellular matrix is a critical step in the colonization of metastatic tumors. The invasion process is thought to be driven by both chemokine signaling and interactions between invading cancer cells and physical components of the metastatic niche, including endothelial cells that line capillary walls and serve as a barrier to both diffusion and invasion of the underlying tissue. Transwell chambers, a tool for generating artificial chemokine gradients to induce cell migration, have facilitated recent work to investigate the chemokine contributions to matrix invasion...
August 16, 2017: Biofabrication
https://www.readbyqxmd.com/read/28812980/application-of-an-in-vitro-digestion-model-for-210po-bioaccessibility-assessment-in-seafood
#11
Carla Roselli, Donatella Desideri, Laura Feduzi, Lucia Ugolini, Maria Assunta Meli
This study aims to investigate the bioaccessibility of 210Po in seafood and the impact of food preparation on this radionuclide. Polonium bioaccessibility is the fraction of 210Po mobilized from food matrices into digestive extractants when applying an in vitro digestion model. The degree of bioaccessibility of 210Po in food has important implications for estimating ingestion doses from this radionuclide. The simulation of gastrointestinal digestion was divided into three stages through the use of synthetic saliva, gastric and bile-pancreas solutions...
August 16, 2017: Journal of Radiological Protection: Official Journal of the Society for Radiological Protection
https://www.readbyqxmd.com/read/28812908/a-quantitative-assessment-of-the-risk-of-human-salmonellosis-arising-from-the-consumption-of-pecans-in-the-united-states
#12
Sofia M Santillana Farakos, Régis Pouillot, Rhoma Johnson, Judith Spungen, Insook Son, Nathan Anderson, Gordon R Davidson, Jane M Van Doren
A quantitative risk assessment was conducted to assess the risk of human salmonellosis acquired from consumption of pecans in the United States. The model considered the potential for Salmonella survival, growth, and recontamination of pecans from the sheller to the consumer, including steps such as immersion in water, drying, conditioning, cracking, partitioning, and storage. Five theoretical microbial reduction treatment levels (1 to 5 log CFU) were modeled. Data from the 2010 to 2013 surveys by the National Pecan Shellers Association were used for initial prevalence and contamination levels...
August 16, 2017: Journal of Food Protection
https://www.readbyqxmd.com/read/28812897/selective-formation-of-functionalized-%C3%AE-quaternary-malononitriles-toward-5-5-disubstituted-pyrrolopyrimidinones
#13
Alan Whitehead, Yong Zhang, Jamie McCabe Dunn, Edward C Sherer, Yu-Hong Lam, John Stelmach, Aaron Sun, Melisa Shiroda, Robert K Orr, Sherman T Waddell, Subharekha Raghavan
A modular, selective approach to complex α-tertiary substituted malononitriles is reported. The method takes advantage of β-ester-substituted α,α-dinitrile alkenes as highly reactive, chemoselective electrophiles for 1,4-additions with organometallic nucleophiles to produce functionally and sterically dense all-carbon quaternary centers. In the presence of a chiral ester auxiliary bearing an aromatic ring, the 1,4-addition occurs with good to excellent selectivity due to favorable cation-π interactions...
August 16, 2017: Organic Letters
https://www.readbyqxmd.com/read/28812880/an-exceptionally-narrow-band-gap-%C3%A2-4-ev-silicate-predicted-in-the-cubic-perovskite-structure-basio3
#14
Hidenori Hiramatsu, Hitoshi Yusa, Ryo Igarashi, Yasuo Ohishi, Toshio Kamiya, Hideo Hosono
The electronic structures of 35 A(2+)B(4+)O3 ternary cubic perovskite oxides, including their hypothetical chemical compositions, were calculated by a hybrid functional method with the expectation that peculiar electronic structures and unique carrier transport properties suitable for semiconductor applications would be hidden in high-symmetry cubic perovskite oxides. We found unique electronic structures of Si-based oxides (A = Mg, Ca, Sr, and Ba, and B = Si). In particular, the unreported cubic BaSiO3 has a very narrow band gap (4...
August 16, 2017: Inorganic Chemistry
https://www.readbyqxmd.com/read/28812874/three-dimensional-highly-stretchable-conductors-from-elastic-fiber-mat-with-conductive-polymer-coating
#15
Shasha Duan, Zhihui Wang, Ling Zhang, Jin Liu, Chunzhong Li
The manufacture of stretchable conductors with well-reserved electrical performance under large-degree deformations via scalable processes remains of great importance. In this work, a highly stretchable 3D conductive framework consisted of polyurethane fiber mat (PUF) and poly(3,4-ethylenedioxythiophene) (PEDOT) is reported through facile approaches, electrospinning and in situ interfacial polymerization, which was then backfilled with poly(dimethylsiloxane) to obtain 3D conductors. The excellent stretchability of the 3D conductive network imparted the as-prepared electrode superior mechanical durability...
August 16, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28812869/entry-inhibitors-a-perspective-for-prevention-of-hepatitis-c-virus-infection-in-organ-transplantation
#16
Che C Colpitts, Raymond T Chung, Thomas F Baumert
Entry inhibitors are emerging as an attractive class of therapeutics for hepatitis C virus (HCV) infection. Entry inhibitors target either virion-associated factors or cellular factors necessary for infection. By blocking entry into cells, entry inhibitors prevent both the establishment of persistent reservoirs and the emergence of resistant variants during viral replication. Furthermore, entry inhibitors protect naïve cells from virus-induced alterations. Combining entry inhibitors with direct-acting antivirals (DAAs) may therefore improve treatment outcomes, particularly in the context of organ transplantation...
August 16, 2017: ACS Infectious Diseases
https://www.readbyqxmd.com/read/28812846/to-what-extent-is-long-term-care-representative-of-elderly-care-a-case-study-of-elderly-care-financing-in-lombardy-italy
#17
Elenka Brenna, Lara Gitto
The ageing of European population has been rapidly increasing during the last decades, and the problem of elderly care financing has become an issue for policy-makers. Long-term care (LTC) financing is considered a suitable proxy of the resources committed to elderly care by each government, but the preciseness of this approximation depends on the extent to which LTC is representative of elderly care within each country. Since there is a broad heterogeneity in LTC funding, organization and setting among European States, it is difficult to find a common parameter representing the public resources destined to the elderly care...
February 25, 2017: International Journal of Health Policy and Management
https://www.readbyqxmd.com/read/28812827/-seeing-the-difference-the-importance-of-visibility-and-action-as-a-mark-of-authenticity-in-co-production-comment-on-collaboration-and-co-production-of-knowledge-in-healthcare-opportunities-and-challenges
#18
Jo Cooke, Joe Langley, Dan Wolstenholme, Susan Hampshaw
The Rycroft-Malone paper states that co-production relies on 'authentic' collaboration as a context for action. Our commentary supports and extends this assertion. We suggest that 'authentic' co-production involves processes where participants can 'see' the difference that they have made within the project and beyond. We provide examples including: the use of design in health projects which seek to address power issues and make contributions visible through iteration and prototyping; and the development of 'actionable outputs' from research that are the physical embodiment of co-production...
October 17, 2016: International Journal of Health Policy and Management
https://www.readbyqxmd.com/read/28812826/a-policy-analysis-on-the-proactive-prevention-of-chronic-disease-learnings-from-the-initial-implementation-of-integrated-measurement-for-early-detection-mido
#19
Roberto Tapia-Conyer, Rodrigo Saucedo-Martínez, Ricardo Mújica-Rosales, Héctor Gallardo-Rincón, Evan Lee, Craig Waugh, Lucía Guajardo, Braulio Torres-Beltrán, Úrsula Quijano-González, Mauricio López-Mendez, Elena Rose Atkinson
Mexico, like many low- and middle-income countries (LMICs), faces an epidemic of chronic non-communicable diseases (NCDs), specifically diabetes, hypertension, obesity, and lipid disorders. Many people with these NCDs may not be aware that they have a disease, pointing to the need for broader screening programs. The traditional prevention policy in Mexico was based on screening with a paper-based risk factor questionnaire. However, this was used to screen patients already seeking healthcare services at facilities, and screening goals were set as a function of the number of questionnaires applied, not number of individuals screened...
February 20, 2017: International Journal of Health Policy and Management
https://www.readbyqxmd.com/read/28812825/evaluating-global-health-partnerships-a-case-study-of-a-gavi-hpv-vaccine-application-process-in-uganda
#20
Carol Kamya, Jessica Shearer, Gilbert Asiimwe, Emily Carnahan, Nicole Salisbury, Peter Waiswa, Jennifer Brinkerhoff, Dai Hozumi
BACKGROUND: Global health partnerships have grown rapidly in number and scope, yet there has been less emphasis on their evaluation. Gavi, the Vaccine Alliance, is one such public-private partnership; in Gavi-eligible countries partnerships are dynamic networks of immunization actors who work together to support all stages and aspects of Gavi support. This paper describes a conceptual framework - the partnership framework - and analytic approach for evaluating the perceptions of partnerships' added value as well as the results from an application to one case in Uganda...
October 26, 2016: International Journal of Health Policy and Management
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