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https://www.readbyqxmd.com/read/28202223/filtration-based-enrichment-of-circulating-tumor-cells-from-all-prostate-cancer-risk-groups
#1
Julius Adebayo Awe, Jeff Saranchuk, Darrel Drachenberg, Sabine Mai
OBJECTIVE: To combine circulating tumor cell (CTC) isolation by filtration and immunohistochemistry to investigate the presence of CTCs in low, intermediate, and high-risk prostate cancer (PCa). CTCs isolated from these risk groups stained positive for both cytokeratin and androgen receptors, but negative for CD45. PATIENTS AND METHODS: Blood samples from 41 biopsy confirmed patients with PCa at different clinical stages such as low, intermediate, and high risk were analyzed...
February 12, 2017: Urologic Oncology
https://www.readbyqxmd.com/read/28184194/eeg-correlates-of-ten-positive-emotions
#2
Xin Hu, Jianwen Yu, Mengdi Song, Chun Yu, Fei Wang, Pei Sun, Daifa Wang, Dan Zhang
Compared with the well documented neurophysiological findings on negative emotions, much less is known about positive emotions. In the present study, we explored the EEG correlates of ten different positive emotions (joy, gratitude, serenity, interest, hope, pride, amusement, inspiration, awe, and love). A group of 20 participants were invited to watch 30 short film clips with their EEGs simultaneously recorded. Distinct topographical patterns for different positive emotions were found for the correlation coefficients between the subjective ratings on the ten positive emotions per film clip and the corresponding EEG spectral powers in different frequency bands...
2017: Frontiers in Human Neuroscience
https://www.readbyqxmd.com/read/28152891/with-quality-and-safety-for-all-risking-optimal-care-with-vip-patients
#3
(no author information available yet)
: 142 Background: The person deemed a VIP is generally considered differentiated from the average person by virtue of fame, notoriety (positive or negative), or success through talent, tenacity or simple luck. Because society often views VIPs as special, this can generate strong feelings ranging from excitement and awe to resentment in those who encounter a VIP. VIPs and/or their entourage may request or demand special attention. The unique factors associated with caring for a VIP can jeopardize patient safety and optimal care of the VIP patient...
March 2016: Journal of Clinical Oncology: Official Journal of the American Society of Clinical Oncology
https://www.readbyqxmd.com/read/28120664/how-to-set-clear-goals-and-achieve-them
#4
Mandy Day-Calder
Do you sometimes look at your colleagues and think everyone else is achieving more? Are you in awe of some nurses' ability to stick to plans and remain unfazed? Well, rest assured, you are not alone.
January 25, 2017: Nursing Standard
https://www.readbyqxmd.com/read/28107483/genetic-divergence-in-domestic-japanese-quail-inferred-from-mitochondrial-dna-d-loop-and-microsatellite-markers
#5
Mitsuo Nunome, Mikiharu Nakano, Ryo Tadano, Ryoka Kawahara-Miki, Tomohiro Kono, Shinji Takahashi, Takaharu Kawashima, Akira Fujiwara, Keijiro Nirasawa, Makoto Mizutani, Yoichi Matsuda
To assess the genetic diversity of domestic Japanese quail (Coturnix japonica) populations, and their genetic relationships, we examined mitochondrial DNA (mtDNA) D-loop sequences and microsatellite markers for 19 Japanese quail populations. The populations included nine laboratory lines established in Japan (LWC, Quv, RWN, WE, AWE, AMRP, rb-TKP, NIES-L, and W), six meat-type quail lines reimported from Western countries (JD, JW, Estonia, NIES-Br, NIES-Fr, and NIES-Hn), one commercial population in Japan, and three wild quail populations collected from three Asian areas...
2017: PloS One
https://www.readbyqxmd.com/read/28063375/identifying-the-barriers-to-antiepileptic-drug-adherence-among-adults-with-epilepsy
#6
REVIEW
Geraldine O' Rourke, Julie Jordan O' Brien
PURPOSE: To identify the barriers to antiepileptic drug (AED) adherence among adults with epilepsy (AWE). The impact of AED non-adherence on quality of life (QoL) was also examined. METHOD: Systematic design (SR) study. A search strategy was undertaken with no time limits, for articles published in English, in MEDLINE, CINANL, PsycINFO, EMBASE, Cochrane databases and grey literature sources. Eligibility criteria included participants with epilepsy over 18 years, who were prescribed AEDs...
December 23, 2016: Seizure: the Journal of the British Epilepsy Association
https://www.readbyqxmd.com/read/28041712/broken-heart-tako-tsubo-or-stress-cardiomyopathy-metaphors-meanings-and-their-medical-impact
#7
REVIEW
Thomas Efferth, Mita Banerjee, Norbert W Paul
The cardiac impact of psychological stress historically and socially understood as boundary experiences of human life has long since become an icon. From the aching heart to the sudden death provoked by awe, horror, grief, anger, and humiliation on one side and extreme enchantment, enthusiasm, and excitement on the other, the broken heart has become a globally recognized and powerful metaphor present from folklore to popular culture to high literature and back to everyday communication. In medicine, the "broken heart syndrome" is described as a relatively new nosological entity that has been used synonymously with the term tako-tsubo or stress cardiomyopathy...
March 1, 2017: International Journal of Cardiology
https://www.readbyqxmd.com/read/28028381/intraocular-pressure-changes-with-positioning-during-laparoscopy
#8
Adewale O Adisa, Oluwatoyin H Onakpoya, Anthony T Adenekan, Oluwaseun O Awe
BACKGROUND AND OBJECTIVES: Pneumoperitoneum during laparoscopy can produce changes in intraocular pressure (IOP) that may be influenced by several factors. In this study, we investigated changes in IOP during laparoscopy with different positioning. METHODS: We recruited adult patients without eye disease scheduled to undergo laparoscopic operation requiring a reverse Trendelenburg tilt (rTr; group A; n = 20) or Trendelenburg tilt (Tr; Group B; n = 20). IOP was measured at 7 time points (T1-T7)...
October 2016: JSLS: Journal of the Society of Laparoendoscopic Surgeons
https://www.readbyqxmd.com/read/28004137/abdominal-wall-endometriosis-differentiation-from-other-masses-using-ct-features
#9
Gail Yarmish, Evis Sala, Debra A Goldman, Yulia Lakhman, Robert A Soslow, Hedvig Hricak, Ginger J Gardner, H Alberto Vargas
PURPOSE: To assess the utility of morphologic and quantitative CT features in differentiating abdominal wall endometriosis (AWE) from other masses of the abdominal wall. METHODS: Retrospective IRB-approved study of 105 consecutive women from two institutions who underwent CT and biopsy/resection of abdominal wall masses. CTs were independently reviewed by two radiologists blinded to final histopathologic diagnoses. Associations between CT features and pathology were tested using Fisher's Exact Test...
December 21, 2016: Abdominal Radiology
https://www.readbyqxmd.com/read/27956006/dynamics-of-three-dimensional-telomere-profiles-of-circulating-tumor-cells-in-patients-with-high-risk-prostate-cancer-who-are-undergoing-androgen-deprivation-and-radiation-therapies
#10
Landon Wark, Thomas Klonisch, Julius Awe, Cecile LeClerc, Brandon Dyck, Harvey Quon, Sabine Mai
INTRODUCTION: Accurate assessment and monitoring of the therapeutic efficacy of locally advanced prostate cancer remains a major clinical challenge. Contrary to prostate biopsies, circulating tumor cells (CTCs) are a cellular source repeatedly obtainable by blood sampling and could serve as a surrogate marker for treatment efficacy. In this study, we used size-based filtration to isolate and enumerate CTCs from the blood of 20 patients with high-risk (any one of cT3, Gleason 8-10, or prostate-specific antigen>20ng/ml), nonmetastatic, and treatment-naive prostate cancer before and after androgen deprivation therapy (ADT) and radiation therapy (RT)...
December 9, 2016: Urologic Oncology
https://www.readbyqxmd.com/read/27942100/abdominal-wall-endometrioma-our-experience-in-vladimir-russia
#11
Mahir Gachabayov, Roman Horta, Dmitriy Afanasyev, Timur Gilyazov
BACKGROUND: Endometriosis is defined as an estrogen-dependent, benign inflammatory disease characterized by the presence of ectopic endometrial implants. Abdominal wall endometrioma (AWE) being a rare entity is a benign tumor defined as ectopic functional, endometrial tissue located in the abdominal wall. SUBJECTS AND METHODS: A retrospective study of 23 female patients treated with AWE in four departments of three centers in Vladimir city, Russia, from January 2010 to December 2014 was performed...
November 2016: Nigerian Medical Journal: Journal of the Nigeria Medical Association
https://www.readbyqxmd.com/read/27929301/the-dark-side-of-the-sublime-distinguishing-a-threat-based-variant-of-awe
#12
Amie M Gordon, Jennifer E Stellar, Craig L Anderson, Galen D McNeil, Daniel Loew, Dacher Keltner
Theoretical conceptualizations of awe suggest this emotion can be more positive or negative depending on specific appraisal processes. However, the emergent scientific study of awe rarely emphasizes its negative side, classifying it instead as a positive emotion. In the present research we tested whether there is a more negative variant of awe that arises in response to vast, complex stimuli that are threatening (e.g., tornadoes, terrorist attack, wrathful god). We discovered people do experience this type of awe with regularity (Studies 1 & 4) and that it differs from other variants of awe in terms of its underlying appraisals, subjective experience, physiological correlates, and consequences for well-being...
December 8, 2016: Journal of Personality and Social Psychology
https://www.readbyqxmd.com/read/27896582/effect-of-irrigation-on-soil-health-a-case-study-of-the-ikere-irrigation-project-in-oyo-state-southwest-nigeria
#13
M A Adejumobi, G O Awe, T P Abegunrin, O M Oyetunji, T S Kareem
Irrigated agriculture is one of the significant contributors to the food security of the millennium development goals (MDGs); however, the modification of soil matrix by irrigation could alter the overall soil health due to changes in soil properties and processes. The objective of the study was to evaluate the effect of irrigation on soil quality status of the Ikere center pivot irrigation project site in Oyo State, southwest Nigeria. Disturbed soil samples were collected from 0 to 30, 30 to 60, and 60 to 90-cm layers from four different sites in three replicates, within the project location for the determination of soil bio-chemical properties...
December 2016: Environmental Monitoring and Assessment
https://www.readbyqxmd.com/read/27881970/the-potential-of-virtual-reality-for-the-investigation-of-awe
#14
Alice Chirico, David B Yaden, Giuseppe Riva, Andrea Gaggioli
The emotion of awe is characterized by the perception of vastness and a need for accommodation, which can include a positive and/or negative valence. While a number of studies have successfully manipulated this emotion, the issue of how to elicit particularly intense awe experiences in laboratory settings remains. We suggest that virtual reality (VR) is a particularly effective mood induction tool for eliciting awe. VR provides three key assets for improving awe. First, VR provides users with immersive and ecological yet controlled environments that can elicit a sense of "presence," the subjective experience of "being there" in a simulated reality...
2016: Frontiers in Psychology
https://www.readbyqxmd.com/read/27876831/persistent-northward-north-atlantic-tropical-cyclone-track-migration-over-the-past-five-centuries
#15
Lisa M Baldini, James U L Baldini, Jim N McElwaine, Amy Benoit Frappier, Yemane Asmerom, Kam-Biu Liu, Keith M Prufer, Harriet E Ridley, Victor Polyak, Douglas J Kennett, Colin G Macpherson, Valorie V Aquino, Jaime Awe, Sebastian F M Breitenbach
Accurately predicting future tropical cyclone risk requires understanding the fundamental controls on tropical cyclone dynamics. Here we present an annually-resolved 450-year reconstruction of western Caribbean tropical cyclone activity developed using a new coupled carbon and oxygen isotope ratio technique in an exceptionally well-dated stalagmite from Belize. Western Caribbean tropical cyclone activity peaked at 1650‚ÄČA.D., coincident with maximum Little Ice Age cooling, and decreased gradually until the end of the record in 1983...
November 23, 2016: Scientific Reports
https://www.readbyqxmd.com/read/27761841/adverse-working-events-in-patients-with-multiple-sclerosis
#16
Chiara Concetta Incerti, Ornella Argento, Giuseppe Magistrale, Elisabetta Ferraro, Carlo Caltagirone, Valerio Pisani, Ugo Nocentini
Multiple sclerosis (MS) and working status have recently arisen great interest. Fatigue, physical disability, cognition, and psychological disturbances have been linked to unemployment, as well to accidents during daily activities. The aim of our study was to determine frequency of different types of accidents at workplace (AWE) and possible clinical differences among employed (MSe) and unemployed (MSu) MS patients. Sixty MS patients (31 employed, 29 unemployed) and twenty healthy control subjects were recruited...
February 2017: Neurological Sciences
https://www.readbyqxmd.com/read/27697963/shock-and-awe-pedagogy
#17
Heidi L Lujan, Stephen E DiCarlo
No abstract text is available yet for this article.
December 2016: Advances in Physiology Education
https://www.readbyqxmd.com/read/27685153/awe-and-scientific-explanation
#18
Piercarlo Valdesolo, Jun Park, Sara Gottlieb
Past research has established a relationship between awe and explanatory frameworks, such as religion. We extend this work, showing (a) the effects of awe on a separate source of explanation: attitudes toward science, and (b) how the effects of awe on attitudes toward scientific explanations depend on individual differences in theism. Across 3 studies, we find consistent support that awe decreases the perceived explanatory power of science for the theistic (Study 1 and 2) and mixed support that awe affects attitudes toward scientific explanations for the nontheistic (Study 3)...
October 2016: Emotion
https://www.readbyqxmd.com/read/27658622/transport-of-a-kinesin-cargo-pair-along-microtubules-into-dendritic-spines-undergoing-synaptic-plasticity
#19
Derrick P McVicker, Adam M Awe, Karl E Richters, Rebecca L Wilson, Diana A Cowdrey, Xindao Hu, Edwin R Chapman, Erik W Dent
Synaptic plasticity often involves changes in the structure and composition of dendritic spines. Vesicular cargos and organelles enter spines either by exocytosing in the dendrite shaft and diffusing into spines or through a kinesin to myosin hand-off at the base of spines. Here we present evidence for microtubule (MT)-based targeting of a specific motor/cargo pair directly into hippocampal dendritic spines. During transient MT polymerization into spines, the kinesin KIF1A and an associated cargo, synaptotagmin-IV (syt-IV), are trafficked in unison along MTs into spines...
September 23, 2016: Nature Communications
https://www.readbyqxmd.com/read/27632153/cross-cultural-similarities-and-differences-in-the-experience-of-awe
#20
Pooya Razavi, Jia Wei Zhang, Daniela Hekiert, Seung Hee Yoo, Ryan T Howell
Current research on awe is limited to Western cultures. Thus, whether the measurement, frequency, and consequences of awe will replicate across non-Western cultures remains unanswered. To address this gap, we validated the dispositional awe scale (Shiota, Keltner, & John, 2006) in 4 countries (United States, Iran, Malaysia, and Poland; N = 1,173) with extensive variations in cultural values (i.e., power distance) and personality profiles (i.e., extraversion and openness). Multigroup factor analyses demonstrated that, across all cultures, a 3-factor model that treats awe, amusement, and pride as 3 unique emotions is superior to a single-factor model that clusters all 3 emotions together...
December 2016: Emotion
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