keyword
https://read.qxmd.com/read/38422003/a-cluster-randomized-controlled-trial-of-a-nurse-led-artificial-intelligence-assisted-prevention-and-management-for-delirium-ai-antidelirium-on-delirium-in-intensive-care-unit-study-protocol
#1
JOURNAL ARTICLE
Shan Zhang, Wei Cui, Shu Ding, Xiangyu Li, Xi-Wei Zhang, Ying Wu
BACKGROUND: Delirium is a common complication among intensive care unit (ICU) patients that is linked to negative clinical outcomes. However, adherence to the Clinical Practice Guidelines for the Prevention and Management of Pain, Agitation/Sedation, Delirium, Immobility, and Sleep Disruption in Adult Patients in the ICU (PADIS guidelines), which recommend the use of the ABCDEF bundle, is sub-optimal in routine clinical care. To address this issue, AI-AntiDelirium, a nurse-led artificial intelligence-assisted prevention and management tool for delirium, was developed by our research team...
2024: PloS One
https://read.qxmd.com/read/38395902/improving-management-of-ards-uniting-acute-management-and-long-term-recovery
#2
REVIEW
Nicola Latronico, M Eikermann, E W Ely, D M Needham
Acute Respiratory Distress Syndrome (ARDS) is an important global health issue with high in-hospital mortality. Importantly, the impact of ARDS extends beyond the acute phase, with increased mortality and disability for months to years after hospitalization. These findings underscore the importance of extended follow-up to assess and address the Post-Intensive Care Syndrome (PICS), characterized by persistent impairments in physical, cognitive, and/or mental health status that impair quality of life over the long-term...
February 23, 2024: Critical Care: the Official Journal of the Critical Care Forum
https://read.qxmd.com/read/38364704/differentiation-of-highly-pathogenic-strains-of-human-jc-polyomavirus-in-neurological-patients-by-next-generation-sequencing
#3
JOURNAL ARTICLE
Eeva Auvinen, Anni Honkimaa, Pia Laine, Sara Passerini, Ugo Moens, Valeria Pietropaolo, Mika Saarela, Leena Maunula, Laura Mannonen, Olli Tynninen, Hannu Haapasalo, Tuomas Rauramaa, Petri Auvinen, Hanna Liimatainen
BACKGROUND: JC polyomavirus (JCPyV) persists asymptomatic in more than half of the human population. Immunocompromising conditions may cause reactivation and acquisition of neurotropic rearrangements in the viral genome, especially in the non-coding control region (NCCR). Such rearranged JCPyV strains are strongly associated with the development of progressive multifocal leukoencephalopathy (PML). METHODS: Using next-generation sequencing (NGS) and bioinformatics tools, the NCCR was characterized in cerebrospinal fluid (CSF; N = 21) and brain tissue (N = 16) samples from PML patients (N = 25), urine specimens from systemic lupus erythematosus patients (N = 2), brain tissue samples from control individuals (N = 2) and waste-water samples (N = 5)...
February 12, 2024: Journal of Clinical Virology
https://read.qxmd.com/read/38343484/effectiveness-of-the-abcdef-method-for-developing-an-institution-specific-pain-management-clinical-resource
#4
JOURNAL ARTICLE
Emily H Garmon, Alaina Tellson, Angela Straza, Kelsey Kohman, David B Morehead, Judy Embry
INTRODUCTION: Comprehensive treatment strategies improve pain management in hospitalized patients, but no conclusive algorithm is currently available. The Audience, Blueprint, Collaborators, Dissemination, Education, Feedback method for pain management resource development (ABCDEF method) has been proposed as an "executable template" for developing clinical resources customized to local practice environments. METHODS: The ABCDEF method was used to develop a proposal for a pain management pamphlet...
2024: Proceedings of the Baylor University Medical Center
https://read.qxmd.com/read/38250248/improving-outcomes-in-mechanically-ventilated-adult-icu-patients-following-implementation-of-the-icu-liberation-abcdef-bundle-across-a-large-healthcare-system
#5
JOURNAL ARTICLE
Juliana Barr, Brenda Downs, Ken Ferrell, Mojdeh Talebian, Seth Robinson, Liesl Kolodisner, Heather Kendall, Janet Holdych
OBJECTIVES: To measure how the ICU Liberation Bundle (aka ABCDEF Bundle or the Bundle) affected clinical outcomes in mechanically ventilated (MV) adult ICU patients, as well as bundle sustainability and spread across a healthcare system. DESIGN: We conducted a multicenter, prospective, cohort observational study to measure bundle performance versus patient outcomes and sustainability in 11 adult ICUs at six community hospitals. We then prospectively measured bundle spread and performance across the other 28 hospitals of the healthcare system...
January 2024: Critical care explorations
https://read.qxmd.com/read/38199062/multicentre-implementation-of-a-quality-improvement-initiative-to-reduce-delirium-in-adult-intensive-care-units-an-interrupted-time-series-analysis
#6
JOURNAL ARTICLE
Victoria S Owen, Selvi Sinnadurai, Jeanna Morrissey, Heather Colaco, Patty Wickson, Donalda Dyjur, Melissa Redlich, Barbara O'Neill, David A Zygun, Christopher J Doig, Jo Harris, Danny J Zuege, Henry T Stelfox, Peter D Faris, Kirsten M Fiest, Daniel J Niven
PURPOSE: The ABCDEF bundle may improve delirium outcomes among intensive care unit (ICU) patients, however population-based studies are lacking. In this study we evaluated effects of a quality improvement initiative based on the ABCDEF bundle in adult ICUs in Alberta, Canada. MATERIAL AND METHODS: We conducted a pre-post, registry-based clinical trial, analysed using interrupted time series methodology. Outcomes were examined via segmented linear regression using mixed effects models...
January 9, 2024: Journal of Critical Care
https://read.qxmd.com/read/38193764/clinical-impact-of-the-implementation-strategies-used-to-apply-the-2013-pain-agitation-sedation-delirium-or-2018-pain-agitation-sedation-delirium-immobility-sleep-disruption-guideline-recommendations-a-systematic-review-and-meta-analysis
#7
JOURNAL ARTICLE
Nicole E Hume, Isabelle Zerfas, Adrian Wong, Michele Klein-Fedyshin, Pamela L Smithburger, Mitchell S Buckley, John W Devlin, Sandra L Kane-Gill
OBJECTIVES: To summarize the effectiveness of implementation strategies for ICU execution of recommendations from the 2013 Pain, Agitation/Sedation, Delirium (PAD) or 2018 PAD, Immobility, Sleep Disruption (PADIS) guidelines. DATA SOURCES: PubMed, CINAHL, Scopus, and Web of Science were searched from January 2012 to August 2023. The protocol was registered with PROSPERO (CRD42020175268). STUDY SELECTION: Articles were included if: 1) design was randomized or cohort, 2) adult population evaluated, 3) employed recommendations from greater than or equal to two PAD/PADIS domains, and 4) evaluated greater than or equal to 1 of the following outcome(s): short-term mortality, delirium occurrence, mechanical ventilation (MV) duration, or ICU length of stay (LOS)...
January 9, 2024: Critical Care Medicine
https://read.qxmd.com/read/38105529/barriers-to-implementing-the-icu-liberation-bundle-in-a-single-center-pediatric-and-cardiac-icus
#8
JOURNAL ARTICLE
Anna McCudden, Hector R Valdivia, Jane L Di Gennaro, Lina Berika, Jerry Zimmerman, Leslie A Dervan
Objectives: The intensive care unit (ICU) Liberation "ABCDEF" Bundle improves outcomes in critically ill adults. We aimed to identify common barriers to Pediatric ICU Liberation Bundle element implementation, to describe differences in barrier perception by ICU staff role, and to describe changes in reported barriers over time. Study Design: A 91-item survey was developed based on existing literature, iteratively revised, and tested by the PICU Liberation Committee at Seattle Children's Hospital, a tertiary free-standing academic children's hospital...
December 17, 2023: Journal of Intensive Care Medicine
https://read.qxmd.com/read/38033207/stopping-delirium-using-the-awake-and-walking-intensive-care-unit-approach-true-mastery-of-critical-thinking-and-the-abcdef-bundle
#9
JOURNAL ARTICLE
Kali Dayton, Mark Hudson, Heidi Lindroth
No abstract text is available yet for this article.
December 15, 2023: AACN Advanced Critical Care
https://read.qxmd.com/read/37981753/comparison-of-sat-and-sbt-conduct-during-the-abc-trial-and-pilot-trial
#10
JOURNAL ARTICLE
Tuqa Alkhateeb, Matthew W Semler, Timothy D Girard, E Wesley Ely, Joanna L Stollings
BACKGROUND: Implementation of the "B" element-both spontaneous awakening trials (SATs) and spontaneous breathing trials (SBTs)-of the ABCDEF bundle improves the outcomes for mechanically ventilated patients. In 2021, the Pragmatic Investigation of optimal Oxygen Targets (PILOT) trial investigating optimal oxygenation targets in patients on mechanical ventilation was completed. OBJECTIVES: To compare SAT and SBT conduct between a randomized controlled trial and current clinical care...
November 19, 2023: Journal of Intensive Care Medicine
https://read.qxmd.com/read/37971720/evaluation-of-the-impact-of-abcdef-bundle-compliance-rates-on-postintensive-care-syndrome-a-secondary-analysis-study
#11
JOURNAL ARTICLE
Daisuke Kawakami, Shigeki Fujitani, Hidenobu Koga, Hisashi Dote, Mumon Takita, Akihiro Takaba, Masaaki Hino, Michitaka Nakamura, Hiromasa Irie, Tomohiro Adachi, Mami Shibata, Jun Kataoka, Akira Korenaga, Tomoya Yamashita, Tomoya Okazaki, Masatoshi Okumura, Takefumi Tsunemitsu
OBJECTIVES: This study aimed to examine the association between ABCDEF bundles and long-term postintensive care syndrome (PICS)-related outcomes. DESIGN: Secondary analysis of the J-PICS study. SETTING: This study was simultaneously conducted in 14 centers and 16 ICUs in Japan between April 1, 2019, and September 30, 2019. PATIENTS: Adult ICU patients who were expected to be on a ventilator for at least 48 hours. INTERVENTIONS: None...
December 1, 2023: Critical Care Medicine
https://read.qxmd.com/read/37954897/lessons-learned-from-a-systematic-hospital-wide-implementation-of-the-abcdef-bundle-a-survey-evaluation
#12
JOURNAL ARTICLE
Joan C Brown, Li Ding, Jynette A Querubin, Carol J Peden, Juliana Barr, Joseph Perren Cobb
OBJECTIVE: We recently reported the first part of a study testing the impact of data literacy training on "assessing pain, spontaneous awakening and breathing trials, choice of analgesia and sedation, delirium monitoring/management, early exercise/mobility, and family and patient empowerment" [ABCDEF [A-F]) compliance. The purpose of the current study, part 2, was to evaluate the effectiveness of the implementation approach by surveying clinical staff to examine staff knowledge, skill, motivation, and organizational resources...
November 2023: Critical care explorations
https://read.qxmd.com/read/37865279/iris-melanoma-review-of-clinical-features-risks-management-and-outcomes
#13
JOURNAL ARTICLE
Elliot Cherkas, Nicholas E Kalafatis, Molly R Marous, Carol L Shields
Primary uveal melanoma is rare and affects approximately 8,000 persons per year worldwide. This malignancy can involve the iris, ciliary body, and choroid. Of these three structures, the iris is the least commonly affected site, representing only 4% of all uveal melanomas. Iris melanoma can arise from iris melanocytic nevus, iris melanocytosis, or de novo. In a longitudinal study of 1,611 patients followed with iris nevus, transformation into melanoma, using Kaplan-Meier estimates, was found in 2.6% by 5 years and 4...
October 19, 2023: Clinics in Dermatology
https://read.qxmd.com/read/37737293/average-booking-curves-draw-exponential-functions
#14
JOURNAL ARTICLE
Masaru Shintani, Ken Umeno
The booking curve time series in perishable asset industries, including hotels, has been studied to manage a demand-supply condition or revenue management (RM). However, due to changing times, e.g., economy and technology, many RM practitioners have put their efforts into catching on to peoples' booking pattern shifts, representing macroscopic changes in booking curves. We investigate macroscopic aspects of booking curves with actual sales data across six properties in the hotel and car-rental industries for two years, considering the difference in the economic environment characterized before and during the COVID-19 epidemic...
September 22, 2023: Scientific Reports
https://read.qxmd.com/read/37631954/prospective-attitudes-towards-respiratory-syncytial-virus-rsv-vaccination-validation-of-a-survey-instrument-among-young-females-in-jordan-pending-vaccine-authorization
#15
JOURNAL ARTICLE
Tleen Kherfan, Malik Sallam
In May 2023, the U.S. FDA advisors endorsed Pfizer's pregnancy-administered vaccine (branded ABRYSVO) to protect infants from respiratory syncytial virus (RSV) infection. Vaccination can reduce the burden of RSV-related respiratory disease, with previous studies showing its substantial medical and financial burden in Jordan. However, pregnant women may exhibit hesitancy to get vaccinated due to concerns about potential risks to themselves or their fetuses. This study aimed to assess the acceptance of the RSV vaccine among young females and identify the determinants influencing their decision using a newly constructed instrument...
August 19, 2023: Vaccines
https://read.qxmd.com/read/37581265/practices-of-the-abcdef-care-bundle-in-intensive-care-units-as-reported-by-nurses-a-cross-sectional-study-from-turkey
#16
JOURNAL ARTICLE
Öznur Erbay Dalli, Derya Akça Doğan, Rıdvan Bayram, Seda Pehlivan, Hicran Yildiz
BACKGROUND: Recent critical care guidelines recommended the evidence-based ABCDEF care bundle for intensive care unit (ICU) patients. However, limited information is available on the implementation of the bundle in Turkish ICUs. AIM: To assess the current practices of the ABCDEF care bundle as reported by ICU nurses. STUDY DESIGN: A cross-sectional study using a web-based survey was conducted. Researchers invited nurses with at least 1 year of ICU experience to participate by sending the link to the research questionnaires they created in Google Forms to the one ICU nurse association and one communication group of which they are members...
August 15, 2023: Nursing in Critical Care
https://read.qxmd.com/read/37449696/clinical-practice-guidelines-for-management-of-pain-agitation-delirium-immobility-and-sleep-disturbance-in-the-intensive-care-unit-the-abcdef-bundle
#17
JOURNAL ARTICLE
Rakesh Bhadade, Minal Harde, Milind Nadkar, Mangesh Tiwasker, Agam Vora, Amit Saraf, Jyotirmoy Pal, Shashank Joshi, Sreenivasmurthy, Rosemarie de Souza
It is crucial to prevent and manage intensive care unit (ICU) distress caused by a pentad of pain, agitation, delirium, immobility, and sleep disturbance (PADIS) to optimize immediate and longterm recovery and outcomes of critically ill patients. This clinical practice guideline provides an update on the prevention, management, and liberation of PADIS in adult ICU patients using an integrated, evidence-based, multidisciplinary ICU protocol: the ABCDEF bundle. ABCDEF bundle incorporates assessment, prevention, and management of pain; both spontaneous awakening trial (SAT) and spontaneous breathing trial (SBT); choice of sedation and analgesia; delirium: assessment, prevention and management, and early mobility and exercise; family involvement and empowerment (ABCDEF) together as a PADIS care bundle...
July 2023: Journal of the Association of Physicians of India
https://read.qxmd.com/read/37399777/clinicians-perceptions-on-implementation-strategies-used-to-facilitate-abcdef-bundle-adoption-a-multicenter-survey
#18
JOURNAL ARTICLE
Audrey Brockman, Anna Krupp, Christina Bach, Jinjian Mu, Eduard E Vasilevskis, Alai Tan, Lorraine C Mion, Michele C Balas
BACKGROUND: Intensive care unit (ICU) clinicians struggle to routinely implement the ICU Liberation bundle (ABCDEF bundle). As a result, critically ill patients experience increased risk of morbidity and mortality. Despite extensive research related to the barriers and facilitators of bundle use, little is known regarding which implementation strategies are used to facilitate its adoption and sustainability. OBJECTIVES: To identify implementation strategies used to increase adoption of the ABCDEF bundle and how those strategies are perceived by end-users (i...
June 30, 2023: Heart & Lung: the Journal of Critical Care
https://read.qxmd.com/read/37351587/evaluation-of-the-impact-of-abcdef-bundle-compliance-rates-on-postintensive-care-syndrome-a-secondary-analysis-study
#19
JOURNAL ARTICLE
Daisuke Kawakami, Shigeki Fujitani, Hidenobu Koga, Hisashi Dote, Mumon Takita, Akihiro Takaba, Masaaki Hino, Michitaka Nakamura, Hiromasa Irie, Tomohiro Adachi, Mami Shibata, Jun Kataoka, Akira Korenaga, Tomoya Yamashita, Tomoya Okazaki, Masatoshi Okumura, Takefumi Tsunemitsu
OBJECTIVES: This study aimed to examine the association between ABCDEF bundles and long-term postintensive care syndrome (PICS)-related outcomes. DESIGN: Secondary analysis of the J-PICS study. SETTING: This study was simultaneously conducted in 14 centers and 16 ICUs in Japan between April 1, 2019, and September 30, 2019. PATIENTS: Adult ICU patients who were expected to be on a ventilator for at least 48 hours. INTERVENTIONS: None...
June 23, 2023: Critical Care Medicine
https://read.qxmd.com/read/37325283/monodactylous-longitudinal-melanonychia-in-pediatric-skin-of-color-a-case-series-and-review
#20
Luis F Andrade, Kayla D Mashoudy, Brian Morrison, Antonella Tosti
INTRODUCTION: Longitudinal melanonychia, a pigmented longitudinal streak on the nail, is a common clinical finding that may be associated with subungual melanoma with varying presentation depending on race and skin tone. It has been long reported that darker skinned ethnicities have a higher prevalence of longitudinal melanonychia in the US population (e.g., African Americans with 77% prevalence) [Indian J Dermatol. 2021;66(4):445], but unfortunately, there are limited studies exclusively looking at longitudinal melanonychia in pediatric patients of color...
June 2023: Skin Appendage Disorders
keyword
keyword
22916
1
2
Fetch more papers »
Fetching more papers... Fetching...
Remove bar
Read by QxMD icon Read
×

Save your favorite articles in one place with a free QxMD account.

×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"

We want to hear from doctors like you!

Take a second to answer a survey question.