keyword
https://read.qxmd.com/read/38524920/survival-of-adult-aml-patients-treated-with-chemotherapy-in-the-u-s-population-by-age-race-and-ethnicity-sex-calendar-year-period-and-aml-subgroup-2001-2019
#21
JOURNAL ARTICLE
Martha S Linet, Rochelle E Curtis, Sara J Schonfeld, Jacqueline B Vo, Lindsay M Morton, Graça M Dores
BACKGROUND: Population-based survival studies of adult acute myeloid leukemia (AML) have not simultaneously evaluated age at diagnosis, race and ethnicity, sex, calendar period or AML subtypes/subgroups among chemotherapy-treated patients. METHODS: For 28,473 chemotherapy-treated AML patients diagnosed at ages ≥20 years in population-based cancer registry areas of the Surveillance, Epidemiology, and End Results Program (2001-2018, followed through 2019), we evaluated 1-month through 5-year relative survival (RS) and 95% confidence intervals (95% CI) using the actuarial method in the SEER∗Stat Survival Session and overall survival (OS) using multivariable Cox regression to estimate proportional hazard ratios (HR) and 95% CI...
May 2024: EClinicalMedicine
https://read.qxmd.com/read/38524592/differential-clinical-outcomes-after-3-versus-5-years-in-a-comparison-of-preoperative-chemotherapy-with-and-without-radiotherapy-in-locally-advanced-rectal-cancer-a-national-cohort-propensity-score-matched-study
#22
JOURNAL ARTICLE
Yuanxin Zhang, Rui Luo, Jingqi Peng, Zichuan He, Delin Tan, Xueping Liu, Hui Wang, Huaiming Wang
BACKGROUND: Preoperative chemotherapy alone might be a good alternative to preoperative chemoradiotherapy for patients with locally advanced rectal cancer, yet long-term real-world data from the same cohort are lacking. METHODS: Patients diagnosed with stage II-III rectal adenocarcinoma from 2011 to 2015 were randomly sampled from the SEER-Plus database to evaluate the superiority of preoperative chemoradiotherapy versus preoperative chemotherapy alone. FINDINGS: A total of 1314 eligible patients were enrolled, with a median follow-up of 74...
March 30, 2024: Heliyon
https://read.qxmd.com/read/38524022/clinical-characteristics-and-prognostic-factors-of-endometrial-cancer-patients-with-liver-metastasis-a-surveillance-epidemiology-and-end-results-database-seer-based-study-of-1-034-women
#23
JOURNAL ARTICLE
Abdulhameed Alhadeethi, Ahmed A Ibrahim, Ahmed Atia, Yasmeen J Alabdallat, Ibraheem M Alkhawaldeh, Mostafa H El Din Moawad
Background There are several patterns of metastatic spread from endometrial cancer (EC). Although studies have been conducted to study the EC population with distant metastasis in the bone and lungs, there is still a lack of studies on liver metastasis. This study aims to evaluate and assess the clinical features and prognostic factors of EC patients with liver metastasis. Methodology We conducted a retrospective cohort study adhering to the guidelines for reporting observational research. We utilized the Surveillance, Epidemiology, and End Results database to gather data on female patients diagnosed with EC and reported liver metastasis...
February 2024: Curēus
https://read.qxmd.com/read/38522261/salivary-gland-adenoid-cystic-carcinoma-in-the-u-s-population-importance-of-grade-site-of-metastases-and-adjuvant-radiation-for-survival
#24
JOURNAL ARTICLE
Asad Ullah, Asim Ahmed, Kue Tylor Lee, Abdul Qahar Khan Yasinzai, James S Lewis
BACKGROUND: Adenoid cystic carcinoma (AdCC) is a rare and relatively heterogenous salivary gland malignancy, for which there is debate regarding grading, and clinical prognostic factors, including the role of adjuvant radiotherapy. METHODS: Surveillance, Epidemiology, and End Results (SEER) data were reviewed for AdCC cases from 2000 to 2018. RESULTS: A total of 1978 patients with AdCC were identified. Most patients were between 50 and 59 years of age (21...
March 20, 2024: American Journal of Otolaryngology
https://read.qxmd.com/read/38521702/construction-and-validation-of-a-nomogram-predicting-the-overall-survival-benefit-of-unilateral-breast-cancer-patients-undergoing-contralateral-prophylactic-mastectomy
#25
JOURNAL ARTICLE
Luyao Dai, Wenyu Yan, Xueting Ren, Dandan Liu, Lidan Chang, Shuai Lin, Hao Wu, Huafeng Kang, Xiaobin Ma
BACKGROUND: Currently, research on the prognostic factors of unilateral breast cancer (UBC) patients receiving contralateral prophylactic mastectomy (CPM) is limited. This study aimed to construct a new nomogram to predict these patients' overall survival (OS). METHODS: In this retrospective study, 88,477 patients who underwent CPM or unilateral mastectomy (UM) were selected from the Surveillance, Epidemiology, and End Results database. Kaplan-Meier curves and Cox regression analyses were used to determine the difference in the impact of the 2 surgical methods on the prognosis...
February 7, 2024: Clinical Breast Cancer
https://read.qxmd.com/read/38520565/persistent-poverty-disparities-in-incidence-and-outcomes-among-oral-and-pharynx-cancer-patients
#26
JOURNAL ARTICLE
Shama Karanth, Shilpi Mistry, Meghann Wheeler, Tomi Akinyemiju, Joel Divaker, Jae Jeong Yang, Hyung-Suk Yoon, Dejana Braithwaite
PURPOSE: Disparities in oral cavity and pharyngeal cancer based on race/ethnicity and socioeconomic status have been reported, but the impact of living within areas that are persistently poor at the time of diagnosis and outcome is unknown. This study aimed to investigate whether the incidence, 5-year relative survival, stage at diagnosis, and mortality among patients with oral cavity and pharyngeal cancers varied by persistent poverty. METHODS: Data were drawn from the SEER database (2006-2017) and included individuals diagnosed with oral cavity and pharyngeal cancers...
March 23, 2024: Cancer Causes & Control: CCC
https://read.qxmd.com/read/38519643/cannabis-use-after-a-cancer-diagnosis-in-a-population-based-sample-of-cancer-survivors
#27
JOURNAL ARTICLE
Mimi Ton, Polly A Newcomb, Salene Jones, Rachel C Malen, Jaimee L Heffner
PURPOSE: This study aimed to characterize the prevalence and correlates of cannabis use and the methods and reasons for use among recently diagnosed cancer survivors in a population sample within Washington state. METHODS: We identified individuals diagnosed with invasive cancers in the prior 6 to 17 months from April 2020 to December 2020 using the Seattle-Puget Sound Surveillance, Epidemiology, and End Results (SEER) cancer registry. Participants (n = 1,515) completed a questionnaire, including demographics, medical history, cannabis use, and other substance use...
March 22, 2024: Cancer Causes & Control: CCC
https://read.qxmd.com/read/38518290/exploring-disparities-in-surgical-recommendations-for-patients-with-primary-intramedullary-spinal-cord-tumors-an-analysis-of-the-surveillance-epidemiology-and-end-results-database-from-2000-to-2019
#28
JOURNAL ARTICLE
Megan Parker, Melanie A Horowitz, Sachiv Chakravarti, Jiaqi Liu, Cathleen C Kuo, Julian Gendreau, Daniel Lubelski, Jordina Rincon-Torroella, Chetan Bettegowda, Debraj Mukherjee
OBJECTIVE: Factors that may drive recommendations for operative intervention for patients with intramedullary spinal cord tumors (ISCTs) have yet to be extensively studied. The authors investigated racial and socioeconomic disparities in the management of patients with primary spinal cord ependymomas and nonependymal gliomas, with the aim of determining the associations between socioeconomic patient characteristics, survival, and recommendations for the resection of primary ISCTs. METHODS: The Surveillance, Epidemiology, and End Results registry was queried to identify all patients > 18 years of age with ISCTs diagnosed between 2000 and 2019...
March 22, 2024: Journal of Neurosurgery. Spine
https://read.qxmd.com/read/38515571/trends-in-survival-of-ovarian-clear-cell-carcinoma-patients-from-2000-to-2015
#29
JOURNAL ARTICLE
Bing-Qian Tian, Shu-Wen Wang, Jing-Ying Xu, San-Gang Wu, Juan Zhou
PURPOSE: To analyze changes in survival outcomes in patients with ovarian clear cell carcinoma (OCCC) treated consecutively over a 16-year period using a population-based cohort. METHODS: We conducted a retrospective analysis of OCCC from 2000 to 2015 using data from the Surveillance, Epidemiology, and End Results (SEER) program. The ovarian cancer-specific survival (OCSS) and overall survival (OS) were analyzed according to the year of diagnosis. Joinpoint Regression Program, Kaplan-Meier analysis, and multivariate Cox regression analyses were used for statistical analysis...
2024: Frontiers in Oncology
https://read.qxmd.com/read/38513830/increased-incidence-of-thyroid-renal-lung-melanoma-bladder-and-prostate-cancers-after-diagnosis-of-primary-cutaneous-b-cell-lymphoma-a-seer-database-analysis
#30
JOURNAL ARTICLE
Lauren Banner, Thomas Z Rohan, Rachel Zachian, Tyler Gross, Henry Y Yang, Daniel Joffe, Pierluigi Porcu, Neda Nikbakht
No abstract text is available yet for this article.
March 19, 2024: Journal of the American Academy of Dermatology
https://read.qxmd.com/read/38512332/three-day-monitoring-of-adhesive-single-lead-electrocardiogram-patch-for-premature-ventricular-complex-prospective-study-for-diagnosis-validation-and-evaluation-of-burden-fluctuation
#31
JOURNAL ARTICLE
Hyo-Jeong Ahn, Eue-Keun Choi, So-Ryoung Lee, Soonil Kwon, Hee-Seok Song, Young-Shin Lee, Seil Oh
BACKGROUND: Wearable electrocardiogram (ECG) monitoring devices are used worldwide. However, data on the diagnostic yield of an adhesive single-lead ECG patch (SEP) to detect premature ventricular complex (PVC) and the optimal duration of wearing an SEP for PVC burden assessment are limited. OBJECTIVE: We aimed to validate the diagnostic yield of an SEP (mobiCARE MC-100, Seers Technology) for PVC detection and evaluate the PVC burden variation recorded by the SEP over a 3-day monitoring period...
March 21, 2024: Journal of Medical Internet Research
https://read.qxmd.com/read/38507655/updated-analysis-of-comparative-toxicity-of-proton-and-photon-radiation-for-prostate-cancer
#32
JOURNAL ARTICLE
James B Yu, David M DeStephano, Brian Jeffers, David P Horowitz, Pamela R Soulos, Cary P Gross, Simon K Cheng
PURPOSE: Previous comparative effectiveness studies have not demonstrated a benefit of proton beam therapy (PBT) compared with intensity-modulated radiation therapy (IMRT) for prostate cancer. An updated comparison of GI and genitourinary (GU) toxicity is needed. METHODS: We investigated the SEER-Medicare linked database, identifying patients with localized prostate cancer diagnosed from 2010 to 2017. Procedure and diagnosis codes indicative of treatment-related toxicity were identified...
March 20, 2024: Journal of Clinical Oncology
https://read.qxmd.com/read/38507268/identification-of-prognostic-factors-and-construction-of-nomogram-to-predict-cancer-specific-survival-for-patients-with-ovarian-granulosa-cell-tumors
#33
JOURNAL ARTICLE
Yue Zhang, Zhen Zhang, Xinyao Ding, Keyi Zhang, Youren Dai, Wenjun Cheng, Chengyan Luo
BACKGROUND: Ovarian granulosa cell tumors (OGCTs) feature low incidence, indolent growth and late recurrence. Treatment for recurrent OGCTs is challenging. METHODS: The present study was designed to explore the prognostic factors and establish a nomogram to predict cancer-specific survival (CSS) for OGCTs patients. Enrolled in the study were 1459 eligible patients in the Surveillance, Epidemiology, and End Results (SEER) database, who were randomized to the training (n = 1021) or testing set (n = 438) at a ratio of 7:3...
March 2024: Cancer reports
https://read.qxmd.com/read/38506561/other-cause-mortality-in-incidental-prostate-cancer
#34
JOURNAL ARTICLE
Francesco Di Bello, Andrea Baudo, Mario de Angelis, Letizia Maria Ippolita Jannello, Carolin Siech, Zhe Tian, Jordan A Goyal, Claudia Collà Ruvolo, Gianluigi Califano, Roberto La Rocca, Simone Morra, Pietro Acquati, Fred Saad, Shahrokh F Shariat, Luca Carmignani, Ottavio de Cobelli, Alberto Briganti, Felix K H Chun, Nicola Longo, Pierre I Karakiewicz
BACKGROUND: In incidental prostate cancer (IPCa), elevated other-cause mortality (OCM) may obviate the need for active treatment. We tested OCM rates in IPCa according to treatment type and cancer grade and we hypothesized that OCM is significantly higher in not-actively-treated patients. METHODS: Within the Surveillance, Epidemiology, and End Results database (2004-2015), IPCa patients were identified. Smoothed cumulative incidence plots as well as multivariable competing risks regression models were fitted to address OCM after adjustment for cancer-specific mortality (CSM)...
March 20, 2024: Prostate
https://read.qxmd.com/read/38505038/optimal-therapeutic-strategy-for-non-small-cell-lung-cancer-with-thoracic-extrathoracic-metastasis-a-study-based-on-seer-database
#35
JOURNAL ARTICLE
Zhehao He, Xuqi Sun, Jinming Xu, Luming Wang, Jun Cheng, Wang Lv, Jian Hu
BACKGROUND: Non-small cell lung cancer (NSCLC) patients with extrathoracic metastasis (EM) are a highly heterogeneous cohort. Some of these patients could benefit from primary tumor surgery. This study aimed to identify potential NSCLC patients with EM suitable for primary tumor resection and to determine the optimal therapeutic strategy. METHODS: NSCLC patients with EM were extracted from the Surveillance, Epidemiology and End Results database between 2010 and 2015...
February 29, 2024: Journal of Thoracic Disease
https://read.qxmd.com/read/38504089/the-development-of-a-prediction-model-based-on-deep-learning-for-prognosis-prediction-of-gastrointestinal-stromal-tumor-a-seer-based-study
#36
JOURNAL ARTICLE
Junjie Zeng, Kai Li, Fengyu Cao, Yongbin Zheng
Accurately predicting the prognosis of Gastrointestinal stromal tumor (GIST) patients is an important task. The goal of this study was to create and assess models for GIST patients' survival patients using the Surveillance, Epidemiology, and End Results Program (SEER) database based on the three different deep learning models. Four thousand five hundred thirty-eight patients were enrolled in this study and divided into training and test cohorts with a 7:3 ratio; the training cohort was used to develop three different models, including Cox regression, RSF, and DeepSurv model...
March 19, 2024: Scientific Reports
https://read.qxmd.com/read/38504063/benefit-and-risk-of-oral-anticoagulant-initiation-strategies-in-patients-with-atrial-fibrillation-and-cancer-a-target-trial-emulation-using-the-seer-medicare-database
#37
JOURNAL ARTICLE
Bang Truong, Lori Hornsby, Brent Fox, Chiahung Chou, Jingyi Zheng, Jingjing Qian
Oral anticoagulants (OACs) are recommended for patients with atrial fibrillation (AFib) having CHA2 DS2 -VASc score ≥ 2. However, the benefits of OAC initiation in patients with AFib and cancer at different levels of CHA2 DS2 -VASc is unknown. We included patients with new AFib diagnosis and a record of cancer (breast, prostate, or lung) from the 2012-2019 Surveillance, Epidemiology, and End Results (SEER)-Medicare database (n = 39,915). Risks of stroke and bleeding were compared between 5 treatment strategies: (1) initiated OAC when CHA2 DS2 -VASc ≥ 1 (n = 6008), (2) CHA2 DS2 -VASc ≥ 2 (n = 8694), (3) CHA2 DS2 -VASc ≥ 4 (n = 20,286), (4) CHA2 DS2 -VASc ≥ 6 (n = 30,944), and (5) never initiated OAC (reference group, n = 33,907)...
March 20, 2024: Journal of Thrombosis and Thrombolysis
https://read.qxmd.com/read/38501551/prognostic-factors-for-liver-metastasis-in-patients-with-small-intestinal-stromal-tumor-a-retrospective-analysis-of-surveillance-epidemiology-and-end-results
#38
JOURNAL ARTICLE
Luojie Liu, Rufa Zhang, Zhenguo Qiao, Ye Ye, Kaijian Xia, Yunfu Feng, Xiaodan Xu
BACKGROUND: Liver metastasis (LIM) is the most common distant site of metastasis in small intestinal stromal tumors (SISTs). The aim of this study was to determine the risk and prognostic factors associated with LIM in patients with SISTs. METHODS: Patients diagnosed with gastrointestinal stromal tumors between 2010 and 2019 were selected from the Surveillance, Epidemiology, and End Results (SEER) database. Univariate and multivariate logistic regression models, as well as a Cox regression model were used to explore the risk factors associated with the development and prognosis of LIM...
March 2024: World Journal of Surgery
https://read.qxmd.com/read/38499940/development-and-validation-of-machine-learning-algorithms-to-predict-1-year-ischemic-stroke-and-bleeding-events-in-patients-with-atrial-fibrillation-and-cancer
#39
JOURNAL ARTICLE
Bang Truong, Jingyi Zheng, Lori Hornsby, Brent Fox, Chiahung Chou, Jingjing Qian
In this study, we leveraged machine learning (ML) approach to develop and validate new assessment tools for predicting stroke and bleeding among patients with atrial fibrillation (AFib) and cancer. We conducted a retrospective cohort study including patients who were newly diagnosed with AFib with a record of cancer from the 2012-2018 Surveillance, Epidemiology, and End Results (SEER)-Medicare database. The ML algorithms were developed and validated separately for each outcome by fitting elastic net, random forest (RF), extreme gradient boosting (XGBoost), support vector machine (SVM), and neural network models with tenfold cross-validation (train:test = 7:3)...
March 18, 2024: Cardiovascular Toxicology
https://read.qxmd.com/read/38498389/a-commentary-on-the-article-entitled-finding-the-minimum-number-of-retrieved-lymph-nodes-in-node-negative-colorectal-cancer-using-real-world-data-and-the-seer-database
#40
JOURNAL ARTICLE
Yueyang Zhang, Zheng Xu, Haitao Zhou
No abstract text is available yet for this article.
March 18, 2024: International Journal of Surgery
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