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https://www.readbyqxmd.com/read/28324052/skeletal-complications-and-mortality-in-thyroid-cancer-a-population-based-study
#1
Palak Choksi, Maria Papaleontiou, Cui Guo, Francis Worden, Mousumi Banerjee, Megan Haymart
Context: Although bone is a common site for tumor metastases, the burden of bone events (bone metastases and skeletal-related events (SREs)) in patients with thyroid cancer is not well known. Objective: To measure the prevalence of bone events and their impact on mortality in patients with thyroid cancer. Patients, Design, and Setting: We identified patients diagnosed with thyroid cancer between 1991-2011 from the linked Surveillance Epidemiology and End Results-Medicare (SEER-Medicare) dataset...
January 25, 2017: Journal of Clinical Endocrinology and Metabolism
https://www.readbyqxmd.com/read/28323992/quantification-of-thyroid-cancer-and-multinodular-goiter-risk-in-the-dicer1-syndrome-a-family-based-cohort-study
#2
Nicholas E Khan, Andrew J Bauer, Kris Ann P Schultz, Leslie Doros, Rosamma M Decastro, Alexander Ling, Maya B Lodish, Laura A Harney, Ron G Kase, Ann G Carr, Christopher T Rossi, Amanda Field, Anne K Harris, Gretchen M Williams, Louis P Dehner, Yoav H Messinger, D Ashley Hill, Douglas R Stewart
Context: The risk of thyroid cancer and multinodular goiter (MNG) in the DICER1 syndrome, a rare tumor-predisposition disorder, is unknown. Objective: To quantify the risk of thyroid cancer and MNG in individuals with the DICER1 syndrome. Design: Family-based cohort study. Setting: National Institutes of Health (NIH) Clinical Center (CC). Participants: The National Cancer Institute DICER1 syndrome cohort consisted of 145 individuals with a DICER1 germline mutation and 135 family controls from 48 families...
February 2, 2017: Journal of Clinical Endocrinology and Metabolism
https://www.readbyqxmd.com/read/28317314/assessing-disruptions-in-adherence-to-antidepressant-treatments-after-breast-cancer-diagnosis
#3
Yi-Ting Chou, Aaron N Winn, Donald L Rosenstein, Stacie B Dusetzina
PURPOSE: Long-term treatment with antidepressants can lessen the symptoms of depression, but health-related crises-such as a cancer diagnosis-may disrupt ongoing depression care. The study aims to estimate the effect of receiving a breast cancer diagnosis on antidepressant adherence among women with depression. METHODS: Using SEER-Medicare administrative claims, we identified women aged 65+ with newly diagnosed breast cancer between 2008 and 2011, who were diagnosed with depression and used antidepressants during the year before pre-diagnosis year...
March 19, 2017: Pharmacoepidemiology and Drug Safety
https://www.readbyqxmd.com/read/28317286/trend-analysis-and-survival-of-primary-gallbladder-cancer-in-the-united-states-a-1973-2009-population-based-study
#4
Rubayat Rahman, Eduardo J Simoes, Chester Schmaltz, Christian S Jackson, Jamal A Ibdah
Primary gallbladder cancer is an aggressive and uncommon cancer with poor outcomes. Our study examines epidemiology, trend, and survival of gallbladder cancer in the United States from 1973 to 2009. We utilized the Surveillance Epidemiology and End Results database (SEER). Frequency and rate analyses on demographics, stage, and survival were compared among non-Hispanic whites, Hispanics, African American, and Asian/Pacific Islanders. A total of 18,124 cases were reported in SEER from 1973 to 2009 comprising 1...
March 20, 2017: Cancer Medicine
https://www.readbyqxmd.com/read/28315902/postoperative-radioactive-iodine-131-ablation-is-not-necessary-among-patients-with-intermediate-risk-differentiated-thyroid-carcinoma-a-population-based-study
#5
Hong Zhang, Yuechang Cai, Li Zheng, Zhanlei Zhang, Ningyi Jiang
OBJECTIVE: To assess the effectiveness of radioactive iodine (RAI) ablation among patients with intermediate-risk differentiated thyroid cancer (DTC) following surgery. SUBJECTS AND METHODS: This population based study obtained information from the Surveillance, Epidemiology, and End Results (SEER) Program Research Data (1973-2013). National Cancer Institute, DCCPS, Surveillance Research Programme, Surveillance Systems Branch, released April 2016, based on the November 2015 submission...
March 20, 2017: Hellenic Journal of Nuclear Medicine
https://www.readbyqxmd.com/read/28314541/risk-of-subsequent-primary-kidney-cancer-after-another-malignancy-a-population-based-study
#6
Omar Abdel-Rahman
BACKGROUND: Population-based data on the development of kidney cancer as a second malignant neoplasm following the diagnosis of other common malignancies are rare. This clinical scenario has been evaluated within the Surveillance, Epidemiology, and End Results (SEER) database. MATERIALS AND METHODS: The SEER-9 database (1973-2013) was queried using the SEER*Stat program to determine the standardized incidence ratios (SIRs) of kidney cancer development following each one of 10 common invasive malignancies (colorectal, breast, prostate, lung, thyroid, corpus uteri, urinary bladder, kidney/renal pelvis, cutaneous melanoma, and non-Hodgkin lymphoma)...
February 27, 2017: Clinical Genitourinary Cancer
https://www.readbyqxmd.com/read/28314407/population-based-results-in-the-management-of-sinonasal-and-ventral-skull-base-malignancies
#7
REVIEW
Rami Abdou, Soly Baredes
Population-based cancer registries allow for data collection on the scale of large populations, outside the limits of a single institution, and facilitate study of rare entities. The SEER database has been used to study more than 7000 cases encompassing a wide variety of relatively rare sinonasal malignant histologies. Clinically useful parameters have been gleaned from these analyses. Important limitations, such as omission of chemotherapy data, surgical approach used, type of radiation administered, and selection and confounding bias, should be considered...
April 2017: Otolaryngologic Clinics of North America
https://www.readbyqxmd.com/read/28304120/comparative-effectiveness-of-chemotherapy-versus-resection-of-the-primary-tumor-as-the-initial-treatment-in-older-patients-with-stage-iv-colorectal-cancer
#8
Hemalkumar B Mehta, Gabriela M Vargas, Deepak Adhikari, Francesca Dimou, Taylor S Riall
AIM: The objective was to determine trends in the use of chemotherapy as the initial treatment and evaluate the comparative effectiveness of initial chemotherapy versus resection of the primary tumour on survival (intention-to-treat analysis) in stage IV colorectal cancer (CRC). METHODS: This cohort study used Surveillance Epidemiology, and End Results (SEER)-Medicare (2000-2011) data, including patients ≥66 years presenting with stage IV CRC. Cox proportional hazards models and instrumental variable analysis were used to determine the association of chemotherapy versus resection of the primary tumour as the initial treatment with 2-year survival...
March 17, 2017: Colorectal Disease: the Official Journal of the Association of Coloproctology of Great Britain and Ireland
https://www.readbyqxmd.com/read/28302450/the-effect-of-local-treatment-modalities-in-patients-with-early-stage-adenocarcinoma-of-the-uterine-cervix-a-population-based-analysis
#9
Juan Zhou, San-Gang Wu, Jia-Yuan Sun, Feng-Yan Li, Huan-Xin Lin, Da-Hong Chen, Zhen-Yu He
BACKGROUND: To determine the optimal local treatment modalities in stage IB-IIA adenocarcinoma (AC) of the uterine cervix and assess the impact of tumor size in the clinical outcomes. METHODS: Patients with a primary diagnosis of stage IB-II cervix AC between 1988 and 2013 were identified using the Surveillance, Epidemiology, and End Results (SEER) database. Cox regression analyses were performed to analyze the effect of local treatment modalities on cause-specific survival (CSS) and overall survival (OS)...
March 13, 2017: International Journal of Surgery
https://www.readbyqxmd.com/read/28301689/the-early-adoption-of-intensity-modulated-radiotherapy-and-stereotactic-body-radiation-treatment-among-older-medicare-beneficiaries-with-prostate-cancer
#10
Bruce L Jacobs, Jonathan G Yabes, Samia H Lopa, Dwight E Heron, Chung-Chou H Chang, Florian R Schroeck, Justin E Bekelman, Jeremy M Kahn, Joel B Nelson, Amber E Barnato
BACKGROUND: Several new prostate cancer treatments have emerged since 2000, including 2 radiotherapies with similar efficacy at the time of their introduction: intensity-modulated radiotherapy (IMRT) and stereotactic body radiation therapy (SBRT). The objectives of this study were to compare their early adoption patterns and identify factors associated with their use. METHODS: By using the Surveillance, Epidemiology, and End Results (SEER)-Medicare database, patients who received radiation therapy during the 5 years after IMRT introduction (2001-2005) and the 5 years after SBRT introduction (2007-2011) were identified...
March 16, 2017: Cancer
https://www.readbyqxmd.com/read/28301662/brain-metastases-in-newly-diagnosed-breast-cancer-a-population-based-study
#11
Allison M Martin, Daniel N Cagney, Paul J Catalano, Laura E Warren, Jennifer R Bellon, Rinaa S Punglia, Elizabeth B Claus, Eudocia Q Lee, Patrick Y Wen, Daphne A Haas-Kogan, Brian M Alexander, Nancy U Lin, Ayal A Aizer
Importance: Population-based estimates of the incidence and prognosis of brain metastases at diagnosis of breast cancer are lacking. Objective: To characterize the incidence proportions and median survivals of patients with breast cancer and brain metastases at the time of cancer diagnosis. Design, Setting, and Participants: Patients with breast cancer and brain metastases at the time of diagnosis were identified using the Surveillance, Epidemiology, and End Results (SEER) database of the National Cancer Institute...
March 16, 2017: JAMA Oncology
https://www.readbyqxmd.com/read/28301349/influence-of-extent-of-lymph-node-evaluation-on-survival-for-pathologically-lymph-node-negative-non-small-cell-lung-cancer
#12
Daniel J Becker, Benjamin P Levy, Heather T Gold, Scott E Sherman, Danil V Makarov, David Schreiber, Juan P Wisnivesky, Harvey I Pass
OBJECTIVES: Despite previous retrospective reports that the number of lymph nodes resected at curative intent surgery for lung cancer correlates with overall survival (OS), no consensus exists regarding the minimal nor optimal number of lymph nodes to resect at curative lung cancer surgery. METHODS: We studied subjects in the Surveillance Epidemiology and End Results Database (SEER) diagnosed with non-small cell lung cancer between 2000 and 2011 who underwent either lobectomy or pneumonectomy and had pathologic negative nodal evaluation...
March 15, 2017: American Journal of Clinical Oncology
https://www.readbyqxmd.com/read/28288541/risk-of-subsequent-cancer-among-pediatric-adult-and-elderly-patients-following-a-primary-diagnosis-of-glioblastoma-multiforme-a-population-based-study-of-the-seer-database
#13
Xuezhen Li, Yanbin Li, Yang Cao, Li Peiliang, Bo Liang, Jidian Sun, Enshan Feng
Purpose/aim of the study: Our objective was to determine the risk of a subsequent malignancy in patients with glioblastoma multiforme (GBM). MATERIALS AND METHODS: Data of patients with a primary diagnosis of GBM were extracted from the Surveillance, Epidemiology, and End Results database. Patients were divided into 3 age groups: pediatric, ≤ 19 years of age; adult, 20-59 years; elderly, ≥ 60 years. Outcomes were overall survival and incidence of second cancer. RESULTS: A total of 24,348 patients with primary GBM were identified during the period from 2004-2013; 349 pediatric, 9,841 adults, and 14,518 elderly...
March 14, 2017: International Journal of Neuroscience
https://www.readbyqxmd.com/read/28285840/secondary-malignancies-after-rectal-cancer-resection-with-and-without-radiation-therapy-a-propensity-adjusted-population-based-seer-analysis
#14
Rene Warschkow, Ulrich Güller, Thomas Cerny, Bruno Martin Schmied, Ludwig Plasswilm, Paul Martin Putora
BACKGROUND: The relationship between radiation therapy for rectal cancer and secondary malignancies is debated. The present study is the first population-based analysis using conventional multivariable analyses as well as propensity score matching to assess this relationship. METHODS: Overall, 77,484 patients after resection of localized or locally advanced rectal adenocarcinoma diagnosed between 1973 and 2012 were identified in the Surveillance, Epidemiology, and End Results (SEER) registry...
March 9, 2017: Radiotherapy and Oncology: Journal of the European Society for Therapeutic Radiology and Oncology
https://www.readbyqxmd.com/read/28284890/access-to-high-volume-surgeons-and-the-opportunity-cost-of-performing-radical-prostatectomy-by-low-volume-providers
#15
Afsaneh Barzi, Eric A Klein, Siamak Daneshmand, Inderbir Gill, David I Quinn, Sarmad Sadeghi
BACKGROUND: Evidence suggests that redirecting surgeries to high-volume providers may be associated with better outcomes and significant societal savings. Whether such referrals are feasible remains unanswered. METHODS: Medicare Provider Utilization and Payment Data, SEER 18, and US Incidence data were used to determine the geographic distribution and radical prostatectomy volume for providers. Access was defined as availability of a high-volume provider within driving distance of 100 miles...
March 8, 2017: Urologic Oncology
https://www.readbyqxmd.com/read/28280613/clinical-characteristics-of-adenosquamous-esophageal-carcinoma
#16
Sai Yendamuri, Usha Malhotra, Mark Hennon, Austin Miller, Adrienne Groman, Alaa Halloon, Mary E Reid
BACKGROUND: Current published information of adenosquamous carcinoma (ASC) of the esophagus in the United States is limited to isolated case reports. We sought to study the clinical characteristics of this tumor using the Surveillance, Epidemiology and End Results (SEER) database. METHODS: Relevant data of all patients with esophageal cancer in the SEER database diagnosed from 1998-2010 was obtained. Demographic, grade, stage, treatment and survival characteristics of patients with ASC were summarized and compared to those patients with adenocarcinoma (ACA) and squamous cell carcinoma (SqCC)...
February 2017: Journal of Gastrointestinal Oncology
https://www.readbyqxmd.com/read/28279886/secondary-gastric-cancer-malignancies-following-a-breast-cancer-diagnosis-a-population-based-analysis
#17
Alyson L Mahar, Daniel J Kagedan, Julie Hallet, Natalie G Coburn
OBJECTIVE: To quantify the population-risk of developing gastric cancer (GC) following breast cancer (BC). METHODS: GC incidence following a ductal or lobular BC were separately compared to incidence in the general United States population using SEER data. RESULTS: GC rates were similar to the general population for ductal BC. Women aged 35-75 with lobular BC had a significantly higher incidence of GC; women aged 40-44 had the highest risk...
March 6, 2017: Breast: Official Journal of the European Society of Mastology
https://www.readbyqxmd.com/read/28279589/difference-of-stage-at-cancer-diagnosis-by-socioeconomic-status-for-four-target-cancers-of-the-national-cancer-screening-program-in-korea-results-from-the-gwangju-and-jeonnam-cancer-registries
#18
Sun-Seog Kweon, Min-Gyeong Kim, Mi-Ran Kang, Min-Ho Shin, Jin-Su Choi
BACKGROUND: The aim of this study was to evaluate whether stage at cancer diagnosis differed according to patient economic status. METHODS: A total of 10,528 patients with cancer of the stomach, colorectum, breast, or cervix, which are target organs of the Korean National Cancer Screening Program (NCSP; fully implemented in 2005) were extracted from population-based cancer registries. The patients were classified into four groups based on socioeconomic status (SES), as determined using their National Health Insurance (NHI) monthly premium at the time of cancer diagnosis...
March 6, 2017: Journal of Epidemiology
https://www.readbyqxmd.com/read/28276812/prognostic-value-of-site-specific-extra-hepatic-disease-in-hepatocellular-carcinoma-a-seer-database-analysis
#19
Hani Oweira, Ulf Petrausch, Daniel Helbling, Jan Schmidt, Arianeb Mehrabi, Othmar Schöb, Anwar Giryes, Omar Abdel-Rahman
BACKGROUND: We the prognostic value of site-specific extra-hepatic disease in hepatocellular carcinoma (HCC) patients registered within the surveillance, epidemiology and end results (SEER) database. METHODS: SEER database (2010-2013) has been queried through SEER*Stat program to determine the prognosis of advanced HCC patients according to the site of extra-hepatic disease. Survival analysis has been conducted through Kaplan Meier analysis. RESULTS: A total of 4396 patients with stage IV HCC were identified in the period from 2010-2013 and they were included into this analysis...
February 23, 2017: Expert Review of Gastroenterology & Hepatology
https://www.readbyqxmd.com/read/28275033/short-form-charlson-comorbidity-index-for-assessment-of-perioperative-mortality-after-radical-cystectomy
#20
Paolo Dell'Oglio, Zhe Tian, Sami-Ramzi Leyh-Bannurah, Vincent Trudeau, Alessandro Larcher, Marco Moschini, Ettore Di Trapani, Umberto Capitanio, Alberto Briganti, Francesco Montorsi, Fred Saad, Pierre I Karakiewicz
Background: The Deyo adaptation of the Charlson comorbidity index (DaCCI), which relies on 17 comorbid condition groupings, represents one of the most frequently used baseline comorbidity assessment tools in retrospective database studies. However, this index is not specific for patients with bladder cancer (BCa) treated with radical cystectomy (RC). The goal of this study was to develop a short-form of the original DaCCI (DaCCI-SF) that may specifically predict 90-day mortality after RC, with equal or better accuracy...
March 2017: Journal of the National Comprehensive Cancer Network: JNCCN
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