Yu Fu, Jia Li, Wenyun Cai, Yulan Huang, Xinlong Liu, Zhongyi Ma, Zhongjie Tang, Xufei Bian, Ji Zheng, Jiayun Jiang, Chong Li
Intratumoral microbiota has become research hotspots, and emerges as a non-negligent new component of tumor microenvironments (TME), due to its powerful influence on tumor initiation, metastasis, immunosurveillance and prognosis despite in low-biomass. The accumulations of microbes, and their related components and metabolites within tumor tissues, endow TME with additional pluralistic features which are distinct from the conventional one. Therefore, it's definitely necessary to comprehensively delineate the sophisticated landscapes of tumor microbe microenvironment, as well as their functions and related underlying mechanisms...
April 2024: Acta Pharmaceutica Sinica. B