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https://www.readbyqxmd.com/read/27925656/mold-and-dampness-exposure-and-allergic-outcomes-from-birth-to-adolescence-data-from-the-bamse-cohort
#1
Jesse D Thacher, Olena Gruzieva, Göran Pershagen, Erik Melén, Johnny C Lorentzen, Inger Kull, Anna Bergström
BACKGROUND: Exposure to moldy or damp indoor environments is associated with allergic disease in young children, but it is unclear if the effects persist to adolescence. Our objective was to assess if exposure to mold or dampness during infancy increases the risk of asthma, rhinitis, or IgE sensitization in children followed from birth to 16 years of age. METHODS: We collected questionnaire derived reports of mold or dampness indicators and allergic outcomes from 3798 children in a Swedish birth cohort (BAMSE)...
December 7, 2016: Allergy
https://www.readbyqxmd.com/read/27923376/immunomodulation-after-ischemic-stroke-potential-mechanisms-and-implications-for-therapy
#2
REVIEW
Cynthia Santos Samary, Paolo Pelosi, Pedro Leme Silva, Patricia Rieken Macedo Rocco
Brain injuries are often associated with intensive care admissions, and carry high morbidity and mortality rates. Ischemic stroke is one of the most frequent causes of injury to the central nervous system. It is now increasingly clear that human stroke causes multi-organ systemic disease. Brain inflammation may lead to opposing local and systemic effects. Suppression of systemic immunity by the nervous system could protect the brain from additional inflammatory damage; however, it may increase the susceptibility to infection...
December 7, 2016: Critical Care: the Official Journal of the Critical Care Forum
https://www.readbyqxmd.com/read/27922129/sonic-horizon-formation-for-oscillating-bose-einstein-condensates-in-isotropic-harmonic-potential
#3
Ying Wang, Yu Zhou, Shuyu Zhou
We study the sonic horizon phenomena of the oscillating Bose-Einstein condensates in isotropic harmonic potential. Based on the Gross-Pitaevskii equation model and variational method, we derive the original analytical formula for the criteria and lifetime of the formation of the sonic horizon, demonstrating pictorially the interaction parameter dependence for the occur- rence of the sonic horizon and damping effect of the system distribution width. Our analytical results corroborate quantitatively the particular features of the sonic horizon reported in previous numerical study...
December 6, 2016: Scientific Reports
https://www.readbyqxmd.com/read/27918291/approximate-analytical-solutions-to-the-double-stance-dynamics-of-the-lossy-spring-loaded-inverted-pendulum
#4
Mohammad Shahbazi, Uluç Saranlı, Robert Babuška, Gabriel A D Lopes
This paper introduces approximate time-domain solutions to the otherwise non-integrable double-stance dynamics of the 'bipedal' spring-loaded inverted pendulum (B-SLIP) in the presence of non-negligible damping. We first introduce an auxiliary system whose behavior under certain conditions is approximately equivalent to the B-SLIP in double-stance. Then, we derive approximate solutions to the dynamics of the new system following two different methods: (i) updated-momentum approach that can deal with both the lossy and lossless B-SLIP models, and (ii) perturbation-based approach following which we only derive a solution to the lossless case...
December 5, 2016: Bioinspiration & Biomimetics
https://www.readbyqxmd.com/read/27915026/effects-of-model-definitions-and-parameter-values-in-finite-element-modeling-of-human-middle-ear-mechanics
#5
Daniel De Greef, Felipe Pires, Joris J J Dirckx
BACKGROUND: Despite continuing advances in finite element software, the realistic simulation of middle ear response under acoustic stimulation continues to be challenging. One reason for this is the wide range of possible choices that can be made during the definition of a model. Therefore, an explorative study of the relative influences of some of these choices is potentially very helpful. METHOD: Three finite element models of the human middle ear were constructed, based on high-resolution micro-computed tomography scans from three different human temporal bones...
November 30, 2016: Hearing Research
https://www.readbyqxmd.com/read/27912962/the-influence-of-traditional-chinese-medicine-constitutions-on-the-potential-repair-capacity-after-osteonecrosis-of-the-femoral-head
#6
Tong Yu, Zhennan Zhang, Limin Xie, Xun Ke, Yang Liu
OBJECTIVES: To explore the effects of traditional Chinese medicine (TCM) constitutions on repair capacity after osteonecrosis of the femoral head (ONFH). DESIGN AND SETTING: Ninety-six patients with TCM constitutions of yang-deficiency, dampness-heat and/or blood-stasis were recruited from the orthopedic outpatient clinic of the Guang'anmen Hospital of the China Academy of Chinese Medical Science. Each patient underwent computed tomography (CT) examination of the hips, and CAD software was used to estimate proximal sclerosis ratios based on the CT images...
December 2016: Complementary Therapies in Medicine
https://www.readbyqxmd.com/read/27910938/modulated-switching-current-density-and-spin-orbit-torques-in-mnga-ta-films-with-inserting-ferromagnetic-layers
#7
Kangkang Meng, Jun Miao, Xiaoguang Xu, Yong Wu, Jiaxing Xiao, Jianhua Zhao, Yong Jiang
We report modulated switching current density and spin-orbit torques (SOT) in MnGa/Ta films with inserting very thin Co2FeAl and Co layers. Ferromagnetic coupling has been found in MnGa/Co2FeAl/Ta, resulting in a decreased effective anisotropy field. On the contrary, in MnGa/Co/Ta, antiferromagnetic coupling plays a dominant role. The switching current density Jc in MnGa/Ta is 8.5 × 10(7) A/cm(2). After inserting 0.8-nm-thick Co2FeAl and Co, theJc becomes 5 × 10(7) A/cm(2) and 9 × 10(7) A/cm(2), respectively...
December 2, 2016: Scientific Reports
https://www.readbyqxmd.com/read/27910510/small-optic-suspensions-for-advanced-ligo-input-optics-and-other-precision-optical-experiments
#8
G Ciani, M A Arain, S M Aston, D Feldbaum, P Fulda, J Gleason, M Heintze, R M Martin, C L Mueller, D M Nanda Kumar, A Pele, D H Reitze, P Sainathan, D B Tanner, L F Williams, G Mueller
We report on the design and performance of small optic suspensions developed to suppress seismic motion of out-of-cavity optics in the input optics subsystem of the Advanced Laser Interferometer Gravitational Wave Observatory. These compact single stage suspensions provide isolation in all six degrees of freedom of the optic, local sensing and actuation in three of them, and passive damping for the other three.
November 2016: Review of Scientific Instruments
https://www.readbyqxmd.com/read/27909688/the-danger-signal-extracellular-atp-is-an-inducer-of-fusobacterium-nucleatum-biofilm-dispersal
#9
Qinfeng Ding, Kai Soo Tan
Plaque biofilm is the primary etiological agent of periodontal disease. Biofilm formation progresses through multiple developmental stages beginning with bacterial attachment to a surface, followed by development of microcolonies and finally detachment and dispersal from a mature biofilm as free planktonic bacteria. Tissue damage arising from inflammatory response to biofilm is one of the hallmark features of periodontal disease. A consequence of tissue damage is the release of ATP from within the cell into the extracellular space...
2016: Frontiers in Cellular and Infection Microbiology
https://www.readbyqxmd.com/read/27909046/capping-protein-modulates-actin-remodeling-in-response-to-ros-during-plant-innate-immunity
#10
Jiejie Li, Lingyan Cao, Christopher J Staiger
Plants perceive microbe-associated molecular patterns (MAMPs) and damage-associated molecular patterns (DAMPs) to activate innate immune signaling events, such as bursts of reactive oxygen species (ROS). The actin cytoskeleton remodels during the first five minutes of innate immune signaling in Arabidopsis epidermal cells; however, the immune signals that impinge on actin cytoskeleton and its response regulators remain largely unknown. Here, we demonstrate that rapid actin remodeling upon elicitation with diverse MAMPs and DAMPs represents a conserved plant immune response...
December 1, 2016: Plant Physiology
https://www.readbyqxmd.com/read/27908056/reconstruction-of-piano-hammer-force-from-string-velocity
#11
Antoine Chaigne
A method is presented for reconstructing piano hammer forces through appropriate filtering of the measured string velocity. The filter design is based on the analysis of the pulses generated by the hammer blow and propagating along the string. In the five lowest octaves, the hammer force is reconstructed by considering two waves only: the incoming wave from the hammer and its first reflection at the front end. For the higher notes, four- or eight-wave schemes must be considered. The theory is validated on simulated string velocities by comparing imposed and reconstructed forces...
November 2016: Journal of the Acoustical Society of America
https://www.readbyqxmd.com/read/27906405/study-of-graphene-plasmons-in-graphene-mos2-heterostructures-for-optoelectronic-integrated-devices
#12
Ruina Liu, Baoxin Liao, Xiangdong Guo, Debo Hu, Hai Hu, Luojun Du, Hua Yu, Guangyu Zhang, Xiaoxia Yang, Qing Dai
The performance of electronic circuits is becoming limited by on-chip digital information transmission. Graphene plasmons with ultra-high confinement and low damping rates offer an effective solution to this problem as they allow for the implementation of optical interconnects. However, direct contact with the semiconductor always deteriorates the plasmonic properties due to large damping of the plasmon in the semiconductor. Here, we studied graphene plasmons in heterostructures of graphene and monolayer MoS2 which represents a promising semiconductor for next-generation electronic devices...
December 1, 2016: Nanoscale
https://www.readbyqxmd.com/read/27903453/repair-of-8-oxo-7-8-dihydroguanine-in-prokaryotic-and-eukaryotic-cells-properties-and-biological-roles-of-the-fpg-and-ogg1-dna-n-glycosylases
#13
Serge Boiteux, Franck Coste, Bertrand Castaing
Oxidatively damaged DNA results from the attack of sugar and base moieties by reactive oxygen species (ROS), which are formed as byproducts of normal cell metabolism and during exposure to endogenous or exogenous chemical or physical agents. Guanine, having the lowest redox potential, is the DNA base the most susceptible to oxidation, yielding products such as 8-oxo-7,8-dihydroguanine (8-oxoG) and 2-6-diamino-4-hydroxy-5-formamidopyrimidine (FapyG). In DNA, 8-oxoG was shown to be mutagenic yielding GC to TA transversions upon incorporation of dAMP opposite this lesion by replicative DNA polymerases...
November 26, 2016: Free Radical Biology & Medicine
https://www.readbyqxmd.com/read/27902718/metal-sounds-stiffer-than-drums-for-ears-but-not-always-for-hands-low-level-auditory-features-affect-multisensory-stiffness-perception-more-than-high-level-categorical-information
#14
Juan Liu, Hiroshi Ando
Most real-world events stimulate multiple sensory modalities simultaneously. Usually, the stiffness of an object is perceived haptically. However, auditory signals also contain stiffness-related information, and people can form impressions of stiffness from the different impact sounds of metal, wood, or glass. To understand whether there is any interaction between auditory and haptic stiffness perception, and if so, whether the inferred material category is the most relevant auditory information, we conducted experiments using a force-feedback device and the modal synthesis method to present haptic stimuli and impact sound in accordance with participants' actions, and to modulate low-level acoustic parameters, i...
2016: PloS One
https://www.readbyqxmd.com/read/27901622/childhood-asthma-in-batumi-georgia-prevalence-correlates-potential-underdiagnosis
#15
Vakhtang Beridze, Lia Abuladze, Naira Partenadze, Tamar Bakhtadze, Joshua Lawson, Jan E Zejda
OBJECTIVE: A relative lack of data for Eastern Europe and unknown epidemiology of childhood asthma in Batumi (Georgia) justified a study aimed at determining the prevalence of physician-diagnosed asthma and related respiratory conditions, a comparison of the prevalence of these conditions between urban and rural children, and identification of their environmental correlates. METHODS: Subjects of the cross-sectional population-based study were 3238 urban and 2081 rural children aged 5-17 years whose respiratory status was assessed using the ISAAC questionnaire...
November 30, 2016: Journal of Asthma: Official Journal of the Association for the Care of Asthma
https://www.readbyqxmd.com/read/27900953/feedback-control-policies-employed-by-people-using-intracortical-brain-computer-interfaces
#16
Francis R Willett, Chethan Pandarinath, Beata Jarosiewicz, Brian A Murphy, William D Memberg, Christine H Blabe, Jad Saab, Benjamin L Walter, Jennifer A Sweet, Jonathan P Miller, Jaimie M Henderson, Krishna V Shenoy, John D Simeral, Leigh R Hochberg, Robert F Kirsch, A Bolu Ajiboye
OBJECTIVE: When using an intracortical BCI (iBCI), users modulate their neural population activity to move an effector towards a target, stop accurately, and correct for movement errors. We call the rules that govern this modulation a 'feedback control policy'. A better understanding of these policies may inform the design of higher-performing neural decoders. APPROACH: We studied how three participants in the BrainGate2 pilot clinical trial used an iBCI to control a cursor in a 2D target acquisition task...
November 30, 2016: Journal of Neural Engineering
https://www.readbyqxmd.com/read/27900210/a-new-lpv-modeling-approach-using-pca-based-parameter-set-mapping-to-design-a-pss
#17
Mohammad B Abolhasani Jabali, Mohammad H Kazemi
This paper presents a new methodology for the modeling and control of power systems based on an uncertain polytopic linear parameter-varying (LPV) approach using parameter set mapping with principle component analysis (PCA). An LPV representation of the power system dynamics is generated by linearization of its differential-algebraic equations about the transient operating points for some given specific faults containing the system nonlinear properties. The time response of the output signal in the transient state plays the role of the scheduling signal that is used to construct the LPV model...
January 2017: Journal of Advanced Research
https://www.readbyqxmd.com/read/27900049/toll-like-receptors-and-cutaneous-melanoma
#18
Ilaria Coati, Serena Miotto, Irene Zanetti, Mauro Alaibac
Innate immune cells recognize highly conserved pathogen-associated molecular patterns (PAMPs) via pattern recognition receptors (PRRs). Previous studies have demonstrated that PRRs also recognize endogenous molecules, termed damage-associated molecular patterns (DAMPs) that are derived from damaged cells. PRRs include Toll-like receptors (TLRs), scavenger receptors, C-type lectin receptors and nucleotide oligomerization domain-like receptors. To date, 10 TLRs have been identified in humans and each receptor responds to a different ligand...
November 2016: Oncology Letters
https://www.readbyqxmd.com/read/27898011/update-on-inflammatory-biomarkers-and-treatments-in-ischemic-stroke
#19
REVIEW
Aldo Bonaventura, Luca Liberale, Alessandra Vecchié, Matteo Casula, Federico Carbone, Franco Dallegri, Fabrizio Montecucco
After an acute ischemic stroke (AIS), inflammatory processes are able to concomitantly induce both beneficial and detrimental effects. In this narrative review, we updated evidence on the inflammatory pathways and mediators that are investigated as promising therapeutic targets. We searched for papers on PubMed and MEDLINE up to August 2016. The terms searched alone or in combination were: ischemic stroke, inflammation, oxidative stress, ischemia reperfusion, innate immunity, adaptive immunity, autoimmunity...
November 25, 2016: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/27896350/characterizing-the-optical-properties-of-single-palladium-coated-core-shell-gold-nanorods-as-multifunctional-orientation-probes
#20
So Young Lee, Ji Won Ha
Bimetallic core-shell gold nanorods are promising multifunctional orientation probes due to the synergetic effect of two different metals, as examined under an optical microscope. Herein, we performed a single particle study to characterize the optical properties of palladium-coated core-shell gold nanorods (Pd-AuNRs) using scattering-based dark-field (DF) and differential interference contrast (DIC) microscopy, and to examine their use as multifunctional orientation probes in biological and physical studies...
November 29, 2016: Physical Chemistry Chemical Physics: PCCP
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