keyword
MENU ▼
Read by QxMD icon Read
search

Sessile serrated polyps

keyword
https://www.readbyqxmd.com/read/29133196/cold-endoscopic-mucosal-resection-of-large-sessile-serrated-polyps-at-colonoscopy-with-video
#1
Nicholas J Tutticci, David G Hewett
BACKGROUND AND AIMS: The optimal technique for the resection of sessile serrated polyps (SSPs) is unknown, with established limitations and risks with conventional polypectomy. Although cold snare polypectomy is safe, the efficacy of piecemeal resection for large lesions is untested. In this study, we evaluate the safety and efficacy of cold endoscopic mucosal resection (EMR) for large SSPs. METHODS: Patients presenting for elective colonoscopy at an academic endoscopy center with 1 or more SSPs ≥10mm in size were enrolled, excluding those on anticoagulants or antiplatelets other than aspirin...
November 10, 2017: Gastrointestinal Endoscopy
https://www.readbyqxmd.com/read/29081443/colonoscopy-examination-requires-a-longer-time-in-patients-with-acromegaly-than-in-other-individuals
#2
Masaya Iwamuro, Miho Yasuda, Kou Hasegawa, Satoshi Fujisawa, Kanako Ogura-Ochi, Yuusaku Sugihara, Keita Harada, Sakiko Hiraoka, Hiroyuki Okada, Fumio Otsuka
This study aimed to determine the prevalence of colorectal neoplasms and to investigate the rate of and time required for cecal intubation in patients with acromegaly. A database search performed at our institution identified 29 patients with acromegaly who underwent colonoscopy. Data regarding the endoscopic, biological, and pathological examinations performed were retrospectively reviewed from the clinical records. Subsequently, the rate of and time required for cecal intubation were investigated in 23 patients with acromegaly and compared with the corresponding data of the control group...
October 28, 2017: Endocrine Journal
https://www.readbyqxmd.com/read/29049128/changing-pathological-diagnosis-from-hyperplastic-polyp-to-sessile-serrated-adenoma-systematic-review-and-meta-analysis
#3
Yaron Niv
The WHO published a new classification of colonic polyps in 2010, including the group of serrated polyps, which can be divided into hyperplastic polyps (HP), traditional serrated adenomas, and sessile serrated adenomas (SSA) or polyps. To assess the rate of re-diagnosis of HP to SSA and to look for possible predictors for changing the diagnosis. English Medical literature searches were performed for 'reassessment' OR 'reclassification' AND 'hyperplastic polyp' OR 'sessile serrated adenoma' till 31 January 2017...
October 18, 2017: European Journal of Gastroenterology & Hepatology
https://www.readbyqxmd.com/read/29043592/factors-associated-with-surveillance-adenoma-and-sessile-serrated-polyp-detection-rates
#4
Jennifer K Maratt, Joseph Dickens, Philip S Schoenfeld, Grace H Elta, Kenya Jackson, Daniel Rizk, Christine Erickson, Stacy B Menees
BACKGROUND: Adenoma detection rate (ADR) and sessile serrated polyp detection rate (SSPDR) data in surveillance colonoscopy are limited. AIMS: Our aim was to determine surveillance ADR and SSPDR and identify associated predictors. METHODS: A retrospective review of subjects who underwent surveillance colonoscopy for adenoma and/or SSP at an academic center was performed. The following exclusion criteria were applied: prior colonoscopy ≤ 3 years, incomplete examination, or another indication for colonoscopy...
October 17, 2017: Digestive Diseases and Sciences
https://www.readbyqxmd.com/read/28979711/clinical-predictors-for-sessile-serrated-polyposis-syndrome-a-case-control-study
#5
Yang Wu, Alexander Mullin, Alina Stoita
AIM: To compared individuals with serrated polyposis syndrome (SPS) to those with sessile serrated adenoma (SSA) and adenomas in the setting of endoscopists with high adenoma detection rates at a secondary and tertiary academic centre. METHODS: Retrospectively we collated the clinical, endoscopic and histological features of all patients with SPS at St Vincent's public and private hospital in the last 3 years. Patients were identified by searching through 2 pathology databases...
September 16, 2017: World Journal of Gastrointestinal Endoscopy
https://www.readbyqxmd.com/read/28940106/en-bloc-endoscopic-mucosal-resection-is-equally-effective-for-sessile-serrated-polyps-and-conventional-adenomas
#6
Amol Agarwal, Sidyarth Garimall, Frank I Scott, Nuzhat A Ahmad, Michael L Kochman, Gregory G Ginsberg, Vinay Chandrasekhara
BACKGROUND: Sessile serrated polyps (SSPs) are associated with higher rates of incomplete resection compared to conventional adenomas after traditional snare polypectomy. Outcomes after endoscopic mucosal resection (EMR) are less established. The aim of this study was to evaluate the rate of residual neoplasia at surveillance colonoscopy for SSPs compared to conventional adenomas ≥ 10 mm after en bloc EMR. METHODS: Retrospective cohort study of consecutive patients referred for EMR of a colonic lesion ≥ 10 mm from 2005 to 2013...
September 22, 2017: Surgical Endoscopy
https://www.readbyqxmd.com/read/28929387/distinct-histopathological-characteristics-in-colorectal-submucosal-invasive-carcinoma-arising-in-sessile-serrated-adenoma-polyp-and-conventional-tubular-adenoma
#7
Takashi Murakami, Hiroyuki Mitomi, Takashi Yao, Tsuyoshi Saito, Tomoyoshi Shibuya, Naoto Sakamoto, Taro Osada, Sumio Watanabe
The histopathological characteristics of colorectal submucosal invasive carcinoma arising in sessile serrated adenoma/polyp (SSA/P), a rare malignant tumour, have not yet been fully elucidated. To investigate the features of such, we retrospectively analysed 40 submucosal invasive carcinomas with SSA/P (CA-SSA/P) and compared them to 129 cases of submucosal invasive carcinoma with conventional tubular adenoma (CA-AD). We additionally performed hMLH1 immunostaining. CA-SSA/Ps were significantly smaller than CA-ADs (P < 0...
September 19, 2017: Virchows Archiv: An International Journal of Pathology
https://www.readbyqxmd.com/read/28927878/risk-of-metachronous-high-risk-adenomas-and-large-serrated-polyps-in-individuals-with-serrated-polyps-on-index-colonoscopy-data-from-the-new-hampshire-colonoscopy-registry
#8
Joseph C Anderson, Lynn F Butterly, Christina M Robinson, Julia E Weiss, Christopher Amos, Amitabh Srivastava
BACKGROUND & AIMS: Surveillance guidelines for serrated polyps (SPs) are based on limited data on longitudinal outcomes of patients. We used the New Hampshire Colonoscopy Registry to evaluate risk of clinically important metachronous lesions associated with SPs, detected during index colonoscopies. METHODS: We collected data from a population-based colonoscopy registry that has been collecting and analyzing data on colonoscopies across the state of New Hampshire since 2004, including rates of adenoma and serrated polyp detection...
September 16, 2017: Gastroenterology
https://www.readbyqxmd.com/read/28927131/protein-expression-of-fragile-histidine-triad-and-cyclooxgenase-2-in-serrated-neoplasia-of-the-colorectum
#9
Akihiro Tamoto, Kazuo Yashima, Kohei Hosoda, Sohei Yamamoto, Soichiro Kawata, Yuichiro Ikebuchi, Kazuya Matsumoto, Koichiro Kawaguchi, Kenichi Harada, Yoshikazu Murawaki, Hajime Isomoto
The adenoma-carcinoma sequence (ACS) and the serrated pathway are two distinct developmental routes leading to the formation of colorectal carcinoma (CRC). However, the mechanism triggered by the serrated pathway remains unclear. Therefore, to clarify the molecular and clinicopathological characteristics of the serrated tumorigenic pathway, immunohistochemistry was used to examine the expression of Fragile Histidine Triad (FHIT), cyclooxygenase-2 (COX-2), MutL homolog 1 (MLH1), MutS protein homolog 2 (MSH2) and P53 in endoscopically resected samples of 62 serrated polyps...
September 2017: Oncology Letters
https://www.readbyqxmd.com/read/28924598/carbon-dioxide-insufflation-is-associated-with-increased-serrated-polyp-detection-rate-when-compared-to-room-air-insufflation-during-screening-colonoscopy
#10
Michael Riverso, Yaseen B Perbtani, Jonathan J D Shuster, Joydeep Chakraborty, Tony S Brar, Mitali Agarwal, Han Zhang, Anand Gupte, Shailendra S Chauhan, Christopher E Forsmark, Peter V Draganov, Dennis Yang
BACKGROUND AND STUDY AIMS : Sessile serrated adenomas (SSA) and traditional serrated adenomas (TSA) have been increasingly recognized as precursors of colorectal cancer. The aim of this study was to compare the effect of carbon dioxide insufflation (CO 2 I) vs. room air insufflation (AI) on serrated polyp detection rate (SPDR) and to identify factors associated with SPDR. PATIENTS AND METHODS : Single-center retrospective cohort study of 2083 screening colonoscopies performed with AI (November 2011 through January 2013) or CO 2 I (February 2013 to June 2015)...
September 2017: Endoscopy International Open
https://www.readbyqxmd.com/read/28906425/impact-of-changeover-to-newer-endoscopic-systems-on-quality-and-efficiency-of-screening-and-surveillance-colonoscopy-equipment-or-endoscopist
#11
Manpreet Singh, Melody Sacatos, Loren Laine
GOALS: The goal of this study is to assess whether changeover to newer endoscopic systems impacts quality or efficiency, and quantify the relation between increased withdrawal time and detection rates of sessile serrated polyps (SSPDR) and adenomas (ADR) in real-world practice. STUDY: Beginning 2 months after new endoscopic systems were implemented at 2 endoscopy units, we included all outpatients undergoing screening/surveillance colonoscopy for 4 months. Outpatients during the same 4-month period 1 year earlier comprised the control group...
September 12, 2017: Journal of Clinical Gastroenterology
https://www.readbyqxmd.com/read/28890813/endocuff-assisted-colonoscopy-significantly-increases-sessile-serrated-adenoma-detection-in-veterans
#12
Michael D Baek, Christian S Jackson, John Lunn, Chris Nguyen, Nicole K Shah, Steve Serrao, David Juma, Richard M Strong
BACKGROUND: Colorectal cancer (CRC) is the second most common cause of cancer related deaths in the United States. Colonoscopy is the gold standard for the detection of CRC. There are many colonoscopy quality measures and among these the adenoma detection rate (ADR) has demonstrated a significant impact in reducing mortality from CRC. The primary aim of our study was to compare ADR and distribution of polyp type in patients undergoing Endocuff-assisted colonoscopy (EAC) versus standard colonoscopy (SC) in a VA system...
August 2017: Journal of Gastrointestinal Oncology
https://www.readbyqxmd.com/read/28865167/colorectal-surveillance-after-segmental-resection-for-young-onset-colorectal-cancer-is-there-evidence-for-extended-resection
#13
V N Kozak, M F Kalady, M M Gamaleldin, J Liang, J M Church
AIM: Although sporadic colorectal cancer (CRC) usually occurs in patients over 50, recent evidence suggests that the incidence is increasing in younger patients. Such patients are theoretically at high risk of metachronous neoplasia and may be candidates for extended, prophylactic, colectomy. This study aimed to define the risk of metachronous cancer/adenomas during follow-up of younger patients who underwent segmental colectomy for CRC. METHOD: A CRC database was used to identify patients aged less than 50 who underwent surgery for CRC between 1994 and 2010...
September 2, 2017: Colorectal Disease: the Official Journal of the Association of Coloproctology of Great Britain and Ireland
https://www.readbyqxmd.com/read/28855108/squamoid-morules-in-the-pseudoinvasive-foci-of-colonic-polyp-morphologically-mimic-invasive-carcinoma
#14
Hee Eun Lee, Vishal S Chandan, Chung-Ta Lee, Tsung-Teh Wu
Colorectal adenomas can show focal squamous differentiation or squamoid morules. We describe histologic findings of squamoid morules in the pseudoinvasive foci of colorectal polyps mimicking invasive carcinoma. Five colonic polyps with squamoid morules in the pseudoinvasive foci were collected. Histologic review and immunostains for cytokeratin (CK) 5/6, p63, synaptophysin, and chromogranin were performed on cases with squamoid morules. Forty-seven consecutive colorectal polyps with pseudoinvasion, none of which showed squamoid morules by histology review, and their clinicopathologic features were compared with the cases containing squamoid morules...
August 27, 2017: Human Pathology
https://www.readbyqxmd.com/read/28853002/the-serrated-polyp-pathway-is-it-time-to-alter-surveillance-guidelines
#15
REVIEW
Brendon O'Connell, Nazar Hafiz, Seth Crockett
PURPOSE OF REVIEW: In this manuscript, we review current surveillance guidelines for serrated polyps (SPs) and discuss how recent studies inform the selection of appropriate surveillance intervals for patients with SPs. RECENT FINDINGS: Large and/or proximal SPs, particularly sessile serrated polyps (SSPs), are associated with increased risk of both synchronous and metachronous neoplasia, including advanced adenomas and colorectal cancer (CRC). Persons harboring multiple SSPs or dysplastic SSPs are at the highest risk...
August 29, 2017: Current Gastroenterology Reports
https://www.readbyqxmd.com/read/28843582/diagnosis-and-predictors-of-sessile-serrated-adenoma-after-educational-training-in-a-large-community-based-integrated-healthcare%C3%A2-setting
#16
Dan Li, John Woolfrey, Sheng-Fang Jiang, Christopher D Jensen, Wei K Zhao, Sanjay Kakar, Monica Santamaria, Greg Rumore, Mary Anne Armstrong, Debbie Postlethwaite, Douglas A Corley, Theodore R Levin
BACKGROUND AND AIMS: Sessile serrated adenomas (SSAs) are precursors of 15% to 30% of colorectal cancers but are frequently underdiagnosed. We sought to measure the SSA detection rate (SDR) and predictors of SSA detection after educational training for community gastroenterologists and pathologists. METHODS: Colonoscopy and pathology data (2010-2014) from 3 medical centers at Kaiser Permanente Northern California were accessed electronically. Gastroenterologists and pathologists attended a training session on SSA diagnosis in 2012...
August 24, 2017: Gastrointestinal Endoscopy
https://www.readbyqxmd.com/read/28842058/distribution-of-colorectal-polyps-implications-for-screening
#17
REVIEW
Carlo Senore, Cristina Bellisario, Nereo Segnan
BACKGROUND: During the last decades data from different studies reported modifications of the topographic distribution of colorectal cancers (CRCs), with an increased frequency of tumours in proximal colonic segments. Given the documented link between adenomas and CRC, a proximal migration of adenomas over time could be expected as well. AIM: To evaluate available evidence about the prevalence of adenomas and of sessile serrated polyps across colonic segments, the changing trends in their distribution across the colon and the diagnostic performance of screening tests currently adopted in population based screening programs for lesions located in different colonic segments...
August 2017: Best Practice & Research. Clinical Gastroenterology
https://www.readbyqxmd.com/read/28828201/deep-learning-for-classification-of-colorectal-polyps-on-whole-slide-images
#18
Bruno Korbar, Andrea M Olofson, Allen P Miraflor, Catherine M Nicka, Matthew A Suriawinata, Lorenzo Torresani, Arief A Suriawinata, Saeed Hassanpour
CONTEXT: Histopathological characterization of colorectal polyps is critical for determining the risk of colorectal cancer and future rates of surveillance for patients. However, this characterization is a challenging task and suffers from significant inter- and intra-observer variability. AIMS: We built an automatic image analysis method that can accurately classify different types of colorectal polyps on whole-slide images to help pathologists with this characterization and diagnosis...
2017: Journal of Pathology Informatics
https://www.readbyqxmd.com/read/28816376/acetic-acid-indigocarmine-mixture-for-evaluating-the-margins-of-sessile-serrated-adenomas-polyps
#19
LETTER
Shunsuke Yamamoto, Morteza Shafazand
No abstract text is available yet for this article.
August 17, 2017: Digestive Endoscopy: Official Journal of the Japan Gastroenterological Endoscopy Society
https://www.readbyqxmd.com/read/28791327/use-of-endocytoscopy-for-identification-of-sessile-serrated-adenoma-polyps-and-hyperplastic-polyps-by-quantitative-image-analysis-of-the-luminal-areas
#20
Yushi Ogawa, Shin-Ei Kudo, Yuichi Mori, Nobunao Ikehara, Yasuharu Maeda, Kunihiko Wakamura, Masashi Misawa, Toyoki Kudo, Takemasa Hayashi, Hideyuki Miyachi, Atsushi Katagiri, Fumio Ishida, Haruhiro Inoue
BACKGROUND AND STUDY AIMS:  Recent studies that used magnifying chromoendoscopy and endocytoscopy (EC) to investigate endoscopic features of sessile serrated adenoma/polyps (SSA/Ps) suggested that a dilated crypt opening was an important indicator of SSA/Ps. However, no studies to date have measured the actual extent of dilatation. Hence, we investigated retrospectively the luminal areas using EC to determine a cutoff value for differentiating SSA/Ps from hyperplastic polyps (HPs). PATIENTS AND METHODS : A total of 101 lesions, including 25 SSA/Ps, 66 HPs, and 10 normal mucosal samples, assessed by an integrated-type EC were collected...
August 2017: Endoscopy International Open
keyword
keyword
22892
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"