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https://www.readbyqxmd.com/read/29785270/distant-lung-metastases-caused-by-a-histologically-benign-phosphaturic-mesenchymal-tumor
#1
Maria P Yavropoulou, Christos Poulios, Christoforos Foroulis, Symeon Tournis, Prodromos Hytiroglou, Kalliopi Kotsa, Isaak Kessisoglou, Pantelis Zebekakis
Tumor-induced osteomalacia (TIO) is a rare form of hypophosphatemia usually caused by phosphaturic mesenchymal tumors (PMTs); the biologic behavior of PMTs is under investigation. Herein we present a case of TIO with a protracted course over 12 years leading to a fatal outcome. A 39-year-old man presented with weakness in 2004 and was found to have decreased serum phosphorus, phosphaturia and low levels of 1,25-dihydroxyvitamin D3. Four years later he developed a painful left calf mass. The lesion was resected, but recurred causing extreme pain and dysfunction...
2018: Endocrinology, Diabetes & Metabolism Case Reports
https://www.readbyqxmd.com/read/29784062/multidrug-resistant-proteus-mirabilis-and-escherichia-coli-causing-fulminant-necrotising-fasciitis-a-case-report
#2
Eugene Vernyuy Yeika, Joyce Bei Foryoung, Derrick Tembi Efie, Eugene Adze Nkwetateba, Paul Nkemtendong Tolefac, Marcelin Ngowe Ngowe
BACKGROUND: Necrotizing fasciitis is a rare soft tissue infection characterized by rapid progressive necrosis with relative sparing of underlying muscles. This case is reported to highlight the emergence of multidrug resistant microbes in recent days which limits the use of empiric antibiotic therapy and necessitates early cultures and sensitivity enabling targeted antibiotic therapy. Factors that lead to antimicrobial resistance especially in sub-Saharan Africa have also been discussed...
May 21, 2018: BMC Research Notes
https://www.readbyqxmd.com/read/29782915/new-insights-into-the-natural-course-of-knee-osteoarthritis-early-regulation-of-cytokines-and-growth-factors-with-emphasis-on-sex-dependent-angiogenesis-and-tissue-remodeling-a-pilot-study
#3
Kalle Kisand, Ann Tamm, Mare Lintrop, Agu Tamm
OBJECTIVE: This study was conducted to identify cytokine profiles associated with radiographic phenotypes of knee osteoarthritis (rKOA) with a focus on early stage of the disease. METHODS: The pilot population study involved 60 middle-aged patients (mean age 50±7.3y.). Standardized weight-bearing anteroposterior and axial radiographs were used to assess rKOA severity in tibiofemoral (TFJ) of patellofemoral joint (PFJ) by grading system (grades 0-3). Luminex (xMAP® ) technology was used to simultaneously assess 60 biomarkers...
May 18, 2018: Osteoarthritis and Cartilage
https://www.readbyqxmd.com/read/29780842/the-nfl-s-chop-block-rule-change-does-it-prevent-knee-injuries-in-defensive-players
#4
Hayden P Baker, Antonios Varelas, Kevin Shi, Michael A Terry, Vehniah K Tjong
Background: The chop block, a football maneuver in which an offensive player blocks an opponent around the thigh while another offensive player engages the same opponent above the waist, was declared illegal by the National Football League (NFL) before the 2016-2017 season. Chop blocks have been hypothesized to be associated with medial collateral ligament and anterior cruciate ligament injury, especially in offensive/defensive linemen. Purpose: To quantify the impact that the chop-block rule change had on the incidence of knee injuries to defensive players in the NFL over 4 seasons (2014-2018)...
April 2018: Orthopaedic Journal of Sports Medicine
https://www.readbyqxmd.com/read/29777746/perioperative-and-long-term-all-cause-mortality-in-patients-with-diabetes-who-underwent-a-lower-extremity-amputation
#5
María Eugenia López-Valverde, Javier Aragón-Sánchez, Ana López-de-Andrés, Viviana Guerrero-Cedeño, Rebeca Tejedor-Méndez, Gerardo Víquez-Molina, Rodrigo Jiménez-García
INTRODUCTION: Long-term mortality of patients with diabetes who undergo lower extremity amputation (LEA) has not been reported in Spain. METHODS: The retrospective cohort included all subjects who underwent LEAs from January 1, 2005 to December 31, 2015 in San Jorge Hospital, Huesca, Spain. Live status of every patient up to September 2017 and the date of death were retrieved using the national death index. RESULTS: The series included 203 patients: 116 patients (57...
May 16, 2018: Diabetes Research and Clinical Practice
https://www.readbyqxmd.com/read/29774599/deep-convolutional-neural-network-for-segmentation-of-knee-joint-anatomy
#6
Zhaoye Zhou, Gengyan Zhao, Richard Kijowski, Fang Liu
PURPOSE: To describe and evaluate a new segmentation method using deep convolutional neural network (CNN), 3D fully connected conditional random field (CRF), and 3D simplex deformable modeling to improve the efficiency and accuracy of knee joint tissue segmentation. METHODS: A segmentation pipeline was built by combining a semantic segmentation CNN, 3D fully connected CRF, and 3D simplex deformable modeling. A convolutional encoder-decoder network was designed as the core of the segmentation method to perform high resolution pixel-wise multi-class tissue classification for 12 different joint structures...
May 17, 2018: Magnetic Resonance in Medicine: Official Journal of the Society of Magnetic Resonance in Medicine
https://www.readbyqxmd.com/read/29772322/free-omental-flap-for-tissue-defect-coverage-after-resection-of-complicated-venous-malformation-in-the-area-of-the-knee
#7
Nicla Settembre, Mario D'Oria, Lucie DekerlE, Charbel Saba, Zakariyae Bouziane, Serguei Malikov
Venous malformations are the most common slow-flow vascular malformations; they are not prone to volume decrease over time and invasive treatment is usually required. There are two main techniques to address the definitive therapy of these lesions: sclerotherapy and surgical excision, each with its own advantages and disadvantages. We report the case of a 56 year-old man who came to our attention with persistent pain after multiple unsuccessful attempts to treat a large venous malformation located in the area of the right knee...
May 14, 2018: Annals of Vascular Surgery
https://www.readbyqxmd.com/read/29752507/changes-of-mechanoreceptors-in-different-state-remnants-of-ruptured-anterior-cruciate-ligament
#8
Bin Li, Yu-Tong Wang, Lun-Hao Bai, Yu Wen
OBJECTIVE: To observe the changes in the quantity and morphology of mechanoreceptors in different-state remnant stumps of ruptured anterior cruciate ligaments (ACLs). METHODS: Specimens of completely ruptured ACL remnants were collected from 57 patients. The injury time from injury to surgery was recorded. According to the degree of pre-operative anterior displacement of knee joint, these patients were divided into two groups: group 1 (≤ 6 mm) and group 2 (> 6 mm)...
May 12, 2018: International Orthopaedics
https://www.readbyqxmd.com/read/29749751/visual-motor-control-of-drop-landing-after-anterior-cruciate-ligament-reconstruction
#9
Dustin R Grooms, Ajit Chaudhari, Stephen J Page, Deborah S Nichols-Larsen, James A Onate
CONTEXT:   Visual feedback is crucial in the control of human movement. When vision is obstructed, alterations in landing neuromuscular control may increase movements that place individuals at risk for injury. Anterior cruciate ligament (ACL) injury may further alter the motor-control response to alterations in visual feedback. The development of stroboscopic glasses that disrupt visual feedback without fully obscuring it has enabled researchers to assess visual-motor control during movements that simulate the dynamic demands of athletic activity...
May 11, 2018: Journal of Athletic Training
https://www.readbyqxmd.com/read/29745216/how-to-compare-results-from-open-with-endovascular-procedures
#10
Marc Bosiers, Koen Deloose, Joren Callaert, Patrick Peeters, Jeroen Wauters
BACKGROUND: According to the guidelines, bypass surgery is still the golden standard treatment in patients with femoropopliteal TASC C and D lesions and life-style limiting claudication or CLI. Over the past few decades, endovascular therapy has made great advancements. However, the success rates of surgical and endovascular procedures cannot be directly compared. According to the surgical term "patency", vessel patency can be maintained even in case of a high grade stenosis, whereas according to the endovascular primary patency definition, being binary restenosis, patency is lost from the moment there is a re-narrowing at any location within the treated segment...
May 9, 2018: Journal of Cardiovascular Surgery
https://www.readbyqxmd.com/read/29736287/acute-parotitis-after-lower-limb-amputation-a-case-report-of-a-rare-complication
#11
Konstantinos Ioannis Avgerinos, Nikolaos Degermetzoglou, Sofia Theofanidou, Georgia Kritikou, Ioannis Bountouris
Background: Postoperative parotitis is a rare complication that occurs usually after abdominal surgery. Parotitis has never been described as a complication of vascular operations, in literature. In the present article, we describe a case of a postamputation parotitis along with its management and its possible pathogenesis. Case Report: An 83-year-old diabetic man was emergently admitted to hospital because of gangrene below the right ankle and sepsis. The patient underwent a lower limb amputation above the knee...
2018: Case Reports in Otolaryngology
https://www.readbyqxmd.com/read/29736262/feasibility-of-robotic-exoskeleton-ambulation-in-a-c4-person-with-incomplete-spinal-cord-injury-a-case-report
#12
Robert M Lester, Ashraf S Gorgey
Introduction: To determine whether an individual with C4 incomplete spinal cord injury (SCI) with limited hand functions can effectively operate a powered exoskeleton (Ekso) to improve parameters of physical activity as determined by swing-time, up-time, walk-time, and total number of steps. Case presentation: A 21-year-old male with incomplete chronic (>1 year postinjury) SCI C4, participated in a clinical exoskeleton program to determine the feasibility of standing up and walking with limited hand functions...
2018: Spinal Cord Series and Cases
https://www.readbyqxmd.com/read/29727867/coronal-knee-malalignment-in-young-adults-and-its-link-to-body-measures
#13
Oded Hershkovich, Ran Thein, Barak Gordon, Gideon Burstein, Shay Tenenbaum, Estela Derazne, Dorit Tzur, Arnon Afek
Our aim was to report the prevalence of knee varus-valgus malalignment (KVVM) and its association with body mass index (BMI) and body height in a healthy and fit young adult population. Information on the disability codes associated with KVVM according to the Regulations of Medical Fitness Determination was retrieved from a medical database containing records of 17-year-old males and females before their recruitment into mandatory military service. Logistic regression models assessed the association between the BMI and body height to KVVM...
May 4, 2018: Journal of Knee Surgery
https://www.readbyqxmd.com/read/29726122/interstitial-microdeletion-of-the-1p34-3p34-2-region
#14
Joseph E Jacher, Jeffrey W Innis
BACKGROUND: Interstitial microdeletions of chromosome 1p34.3p34.2 are rare, but are continuing to be identified by the use of chromosome microarray. There have been fewer than 10 individuals identified who have deletions of the 1p34.3p34.2 region; all of these previously described individuals have deletions of the AGO1, AGO3, GRIK3, SLC2A1, or RIMS3 genes. Haploinsufficiency of these genes has been associated with neurodevelopmental delays. METHODS: Chromosome microarray, quantitative PCR, and fluorescence in situ hybridization were performed with DNA extracted from peripheral blood...
May 3, 2018: Molecular Genetics & Genomic Medicine
https://www.readbyqxmd.com/read/29721632/acute-lower-limb-ischemia-and-intestinal-necrosis-due-to-arterial-tumor-embolism-from-advanced-lung-cancer-a-case-report-and-literature-review
#15
Sayuri Togo, Terutoshi Yamaoka, Kazutoyo Morita, Kazuomi Iwasa, Yukihiko Aoyagi, Yumi Oshiro, Takatoshi Fujishita, Hideki Yokoyama, Takashi Matsui, Takashi Nishizaki
BACKGROUND: Arterial tumor embolism (ATE) is a rare but life-threating complication. PRESENTATION OF CASE: A 55-year-old man with acute lower-limb ischemia was referred to our hospital after endovascular intervention failed and underwent above-the-knee amputation for severe limb necrosis. On postoperative day 8, he developed small bowel necrosis and underwent resection. Histopathological examination of the resected bowel revealed that the submucosal arterial emboli were positive for the markers of squamous cells...
May 2, 2018: Surgical Case Reports
https://www.readbyqxmd.com/read/29701409/acute-iatrogenic-limb-ischaemia-a-report-of-2-late-presentation-cases
#16
Ricardo Correia, Ana Garcia, Frederico Gonçalves, Rodolfo Abreu, Rita Ferreira, Nelson Camacho, Joana Catarino, Maria Emília Ferreira
INTRODUCTION: With increasing use of percutaneous vascular procedures, access complications that present to a vascular surgeon increase. The most limb-threatening condition is acute limb ischaemia. Acute limb ischaemia is the most common vascular surgical emergency. In spite of recent advances in vascular surgery, it continues to carry a poor prognosis, if not early diagnosed and managed. METHODS: This is a case-report of 2 patients referenced to a vascular surgery emergency department of a tertiary hospital with late acute limb ischaemia...
July 2017: Revista Portuguesa de Cirurgia Cardio-torácica e Vascular
https://www.readbyqxmd.com/read/29691170/outcomes-of-articulating-spacers-with-autoclaved-femoral-components-in-total-knee-arthroplasty-infection
#17
Daniel E Goltz, E Grant Sutter, Michael P Bolognesi, Samuel S Wellman
BACKGROUND: In 2-stage revision of total knee arthroplasty (TKA) infection, articulating antibiotic spacers show similar eradication rates and superior range of motion compared with static spacers. This study evaluated infection control and other outcomes in articulating spacers with an autoclaved index femoral component. METHODS: We reviewed 59 patients who underwent 2-stage treatment of TKA infection using articulating antibiotic spacers with an autoclaved femoral component with at least 2-year follow-up (mean: 5...
March 30, 2018: Journal of Arthroplasty
https://www.readbyqxmd.com/read/29691166/improved-perioperative-care-of-elective-joint-replacement-patients-the-impact-of-an-orthopedic-perioperative-hospitalist
#18
Steven J Fitzgerald, Terrence C Palmer, Matthew J Kraay
BACKGROUND: We developed an orthopedic hospitalist fellowship program for our total joint replacement program at a large urban academic medical center. The goal of the program was to improve patient outcomes, quality, and healthcare value through collaborative perioperative care and improved care coordination. This study evaluates the implementation and impact of our modified Hospitalist-Orthopaedic Team Co-management model on quality and performance metrics. METHODS: We reviewed our Quality Institute data using 3 databases for the 16 months before (PreOH) and 18 months after (PostOH) implementation...
March 21, 2018: Journal of Arthroplasty
https://www.readbyqxmd.com/read/29690818/in-situ-popliteal-tibial-bypass-with-the-short-saphenous-vein-through-a-posterior-approach-for-limb-salvage
#19
Sosei Kuma, Kohichi Morisaki, Jin Okazaki, Shinsuke Mii
A 69-year-old female patient was admitted to our hospital with gangrene of her left first and second digits. Angiography showed a diffuse occlusive lesion from the external iliac artery to the crural arteries. Endovascular therapy to the external iliac artery, above-knee femoropopliteal bypass with a polytetrafluoroethylene graft, and popliteal-tibial bypass through a posterior approach with the short saphenous vein graft were performed in 3 stages because the length of the great saphenous vein that was suitable for grafting was insufficient...
January 1, 2018: Vascular and Endovascular Surgery
https://www.readbyqxmd.com/read/29686901/reliability-and-construct-validity-of-the-sens-motion%C3%A2-activity-measurement-system-as-a-tool-to-detect-sedentary-behaviour-in-patients-with-knee-osteoarthritis
#20
Cecilie Bartholdy, Henrik Gudbergsen, Henning Bliddal, Morten Kjærgaard, Kasper Lundberg Lykkegaard, Marius Henriksen
Physical inactivity is important to address, and an objective way of measuring inactivity is by accelerometry. The objective of this study was to determine the reliability and construct validity of the SENS motion system to record physical activity and inactivity in patients with knee osteoarthritis. Participants with an age > 40 years and an average weekly pain above 0 on a numeric rating scale (0 = no pain, 10 = worst pain) were included. Participants had a total of two study visits and at each visit participants completed a standardized activity...
2018: Arthritis
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