Read by QxMD icon Read

Dental injurents

Shaul Lin, Nir Pilosof, Munir Karawani, Ronald Wigler, Arieh Y Kaufman, Sorin T Teich
BACKGROUND: This study explores the pattern of complications occurrence resulting from traumatic dental injuries, the relation of this pattern to the number of years from the time of the injury to its first diagnosis, and other contributing characteristics such as root development and trauma characteristic. MATERIAL AND METHODS: Patients' data treated following dental trauma from 2002 to 2014 were classified and grouped according to age, gender, tooth type, injury type, diagnosis and the time that elapsed between the traumatic event and the diagnosis of complications (TIC)...
October 2016: Journal of Clinical and Experimental Dentistry
Jieun Jung, Jong-Wan Kim, Ho-Jin Moon, Jin Young Hong, Jung Keun Hyun
Neural stem cells (NSCs) have a high potency for differentiation to neurons and glial cells for replacement of damaged cells and paracrine effects for the regeneration and remyelination of host axons. Dental pulp is known to have a potential to differentiate into neural-like cells; therefore, dental pulp may be used as an autologous cell source for neural repair. In this study, we selectively expanded stem cells from human dental pulp in an initial culture using NSC media under xeno- and serum-free conditions...
2016: Stem Cells International
Stefan Hartwig, Andreas Boettner, Christian Doll, Jan O Voss, Moritz Hertel, Saskia Preissner, Jan D Raguse
BACKGROUND/AIMS: Intermaxillary fixation is a standard procedure for the treatment of mandibular fractures or in orthognathic surgery. Pre-drilling for screws poses the risk of accidental tooth-root injury, potentially leading to further pathological processes. Limited evidence about accidental tooth injury during intermaxillary fixation is available due to heterogenous study designs. The aim of this study was to evaluate the risk of root trauma using pre-drilled transgingival fixation screws and the clinical consequences for the affected teeth...
September 28, 2016: Dental Traumatology: Official Publication of International Association for Dental Traumatology
Ahmet Akgül, Musa Cirak, Tansu Birinci
Platelet-rich plasma (PRP) is an autologous concentrated preparation of human platelets contained in a small volume of plasma that is characterized by hemostatic and tissue-repairing effects. Being enriched by various kinds of growth factors, and their tissue-repairing effects have made them the focus of attention for use in tissue regeneration. PRP has been safely used and documented in many different fields, including orthopedics, sports injuries, dental and periodontal surgery, and cosmetic, plastic, cardiovascular, general, and maxillofacial surgery...
September 6, 2016: Lymphatic Research and Biology
Fanny Chmilewsky, Warda Ayaz, James Appiah, Imad About, Seung-Hyuk Chung
Given the importance of sensory innervation in tooth vitality, the identification of signals that control nerve regeneration and the cellular events they induce is essential. Previous studies demonstrated that the complement system, a major component of innate immunity and inflammation, is activated at the injured site of human carious teeth and plays an important role in dental-pulp regeneration via interaction of the active Complement C5a fragment with pulp progenitor cells. In this study, we further determined the role of the active fragment complement C5a receptor (C5aR) in dental nerve regeneration in regards to local secretion of nerve growth factor (NGF) upon carious injury...
2016: Scientific Reports
Fernando Domingo, Elizabeth Dale, Cuilan Gao, Cynthia Groves, J Daniel Stanley, Robert A Maxwell, Jimmy L Waldrop
BACKGROUND: Mandibular fractures are common facial injuries and treatment may be complicated by post-operative infection. Risk of infection from contamination with oral flora is well established but no consensus exists regarding antibiotic prophylaxis. The purpose of this study is to assess risk factors and perioperative antibiotics on surgical site infection (SSI) rates following mandibular fracture surgery. METHODS: Retrospective medical record review was completed for trauma patients of any age surgically treated for mandibular fractures at a Level I Trauma Center from September 2006 to June 2012...
August 18, 2016: Journal of Trauma and Acute Care Surgery
Toshiya Nonoyama, Yoshihiro Shimazaki, Haruo Nakagaki, Shinpei Tsuge
AIM: Students often injure their teeth during participation in school-based sports clubs. This study examined the frequencies and types of dental injuries sustained at school sports clubs and compared the risk of dental injury among different sports. METHODS: Based on injury statistics from the Japan Sport Council of the junior high schools and high schools in seven prefectures during fiscal year 2006, the risk of dental injury was estimated using a rate ratio (RR) by calculating the ratio of occurrence of dental injury under various circumstances...
July 24, 2016: International Dental Journal
H J Kim, Y A Cho, Y M Lee, S Y Lee, W J Bae, E C Kim
This study aimed to investigate the role of PIN1 on the hepatic differentiation of human dental pulp stem cells (hDPSCs) and its signaling pathway, as well as the potential therapeutic effects of hDPSC transplantation and PIN1 inhibition on CCl4 (carbon tetrachloride)-induced liver fibrosis in mice. The in vitro results showed that hepatic differentiation was suppressed by infection with adenovirus-PIN1 and promoted by PIN1 inhibitor juglone via the downregulation of Wnt3a and β-catenin. Compared with treatment with either hDPSC transplantation or juglone alone, the combination of hDPSCs and juglone into CCl4-injured mice significantly suppressed liver fibrosis and restored serum levels of alanine transaminase, aspartate transaminase, and ammonia...
July 20, 2016: Journal of Dental Research
K Y Yang, M J Kim, J S Ju, S K Park, C G Lee, S T Kim, Y C Bae, D K Ahn
Previous studies have demonstrated that botulinum toxin type A (BoNT-A) attenuates orofacial nociception. However, there has been no evidence of the participation of the voltage-gated sodium channels (Navs) in the antinociceptive mechanisms of BoNT-A. This study investigated the cellular mechanisms underlying the antinociceptive effects of BoNT-A in a male Sprague-Dawley rat model of trigeminal neuropathic pain produced by malpositioned dental implants. The left mandibular second molar was extracted under anesthesia, followed by a miniature dental implant placement to induce injury to the inferior alveolar nerve...
September 2016: Journal of Dental Research
Sormani Bento Fernandes de Queiroz, Valthierre Nunes de Lima, Pedro Henrique Gonçalves Holanda Amorim, Osvaldo Magro-Filho, Rivadávio Fernandes Batista Amorim
Use of imaging tools like digital C-arm, tridimensional tomography, and navigational surgery has proven its value to the surgical removal of broken needles. A 32-year-old patient was referred for evaluation of a fractured needle during inferior alveolar nerve block attempt few days before. The patient complained of a pricking sensation at the injured area while moving the neck. A contrasted computed tomography was performed for further evaluation of the needle toward the vascular network of the neck, showing a close location by the left facial artery, parallel to the styloid process of the temporal bone...
June 2016: Journal of Craniofacial Surgery
Renjith Parameswaran Nair, Changyu Zheng, Gulshan Sunavala-Dossabhoy
Normal tissues that lie within the portals of radiation are inadvertently damaged. Salivary glands are often injured during head and neck radiotherapy. Irreparable cell damage results in a chronic loss of salivary function that impairs basic oral activities, and increases the risk of oral infections and dental caries. Salivary hypofunction and its complications gravely impact a patient's comfort. Current symptomatic management of the condition is ineffective, and newer therapies to assuage the condition are needed...
2016: Journal of Visualized Experiments: JoVE
G Lagvilava, Z Gvenetadze, E Gibradze, T Danelia, G Gvenetadze
Maxillofacial traumatic injuries concomitant with craniocerebral trauma are still considered as an actual problem in emergency medicine. For this category of patients one of the dangerous and severe complications is development of inflammatory process in the injured areas. Fracture lines of upper and middle facial zones pass through the accessory sinuses of the nose, maxillary/upper dental arch area and are considered to be open and infected fractures. Combination of these fractures with craniocerebral injuries and especially, with open traumas creates predisposition for development of inflammatory processes in CNS that can result in heavy outcome...
February 2016: Georgian Medical News
Patricia L Carlisle, Teja Guda, David T Silliman, Wen Lien, Robert G Hale, Pamela R Brown Baer
OBJECTIVES: To validate a critical-size mandibular bone defect model in miniature pigs. MATERIALS AND METHODS: Bilateral notch defects were produced in the mandible of dentally mature miniature pigs. The right mandibular defect remained untreated while the left defect received an autograft. Bone healing was evaluated by computed tomography (CT) at 4 and 16 weeks, and by micro-CT and non-decalcified histology at 16 weeks. RESULTS: In both the untreated and autograft treated groups, mineralized tissue volume was reduced significantly at 4 weeks post-surgery, but was comparable to the pre-surgery levels after 16 weeks...
February 2016: Journal of the Korean Association of Oral and Maxillofacial Surgeons
Steven R Jefferies
Vital pulp therapy is the general concept involved in the "regenerative" restorative treatment of the reversibly injured dental pulp with the intention of maintaining its vitality in a restored, functioning tooth. While this procedure has been attempted with various materials and techniques over a period of several centuries, the advent of hard-setting calcium hydroxide materials in the late 1950s made the procedure of direct pulp capping a more routine and relatively predictable procedure. More recently, in the mid 1990s, a new type of water-based, "hydraulic-type," calcium silicate-based cement, mineral trioxide aggregate (MTA), was introduced to dentistry as a possible alternative to the established standard of hard-setting calcium hydroxide...
March 2016: Journal of Esthetic and Restorative Dentistry
Anna Oldin, Jesper Lundgren, Jörgen G Norén, Agneta Robertson
AIM: To investigate general unintentional injuries (GUI) and traumatic dental injuries (TDI) in relation to behavioral and psychosocial strengths and difficulties among Swedish children aged 0-17 years, and to investigate general unintentional injuries in relation to temperament and socioeconomic status among the same children. SUBJECTS AND METHODS: The study included 2363 children in four different age cohorts aged 3, 7, 11, and 15 years at the study start. Twelve Public Dental Service clinics in Sweden participated, representing different types of demographic areas, both rural and urban...
August 2016: Dental Traumatology: Official Publication of International Association for Dental Traumatology
(no author information available yet)
An injured patient may be the last thing dentists want to think about. However, in reality, patients can be injured during dental treatment or as the result of an incident such as a slip and fall in the office. Treatment-related injuries can run the gamut and include burns, lacerations, swallowed objects and allergic reactions, according to The Dentists Insurance Company.
2015: HDA Now
Lisa Fink, Alexander M Reiter
A search of the medical and dental records at the Matthew J. Ryan Veterinary Hospital of the University of Pennsylvania was conducted to identify dogs that received full or partial prosthodontic crowns over a 13-year period (2000-2012). Forty-one dogs with a total of 68 prosthodontic crowns were identified. Further criteria for acceptance into the study included presence of complete medical records containing adequate information pertaining to the procedures performed, and current follow-up either by telephone, electronic mail, or via in-person examination...
2015: Journal of Veterinary Dentistry
L Ma, S C Wang, J Tong, Y Hu, Y Q Zhang, Q Yu
AIM: To investigate the expression pattern of Notch signaling in odontoblast-like cells stimulated by lipopolysaccharide (LPS) in vitro, and in injured rat dental pulp in vivo. METHODOLOGY: Mouse odontoblast-like cells (MDPC-23) were exposed to LPS. Expression of Notch-related genes was detected by Real-time PCR. A rat pulpitis model was established by mechanical injury and LPS plus mechanical injury followed by analysis of expression of Notch2 by immunohistochemical staining...
November 17, 2015: International Endodontic Journal
Maitane Aurrekoetxea, Patricia Garcia-Gallastegui, Igor Irastorza, Jon Luzuriaga, Verónica Uribe-Etxebarria, Fernando Unda, Gaskon Ibarretxe
Dental pulp stem cells, or DPSC, are neural crest-derived cells with an outstanding capacity to differentiate along multiple cell lineages of interest for cell therapy. In particular, highly efficient osteo/dentinogenic differentiation of DPSC can be achieved using simple in vitro protocols, making these cells a very attractive and promising tool for the future treatment of dental and periodontal diseases. Among craniomaxillofacial organs, the tooth and salivary gland are two such cases in which complete regeneration by tissue engineering using DPSC appears to be possible, as research over the last decade has made substantial progress in experimental models of partial or total regeneration of both organs, by cell recombination technology...
2015: Frontiers in Physiology
Yuqing Zhu, Hui Chen, Lian Cen, Jun Wang
BACKGROUND/AIM: The influence of abutment tooth position and adhesive point dimension on rigidity of wire-composite splints, used in dental trauma, was evaluated in vitro. MATERIALS AND METHODS: A commercial artificial resin model was used. The central incisors served as injured teeth with increased mobility (degrees of loosening II tooth 21 and III tooth 11), whereas teeth 12/22 or teeth 13/23 served as non-injured teeth with physiological mobility. Horizontal and vertical tooth mobility before and after splinting was assessed, using a universal testing machine...
June 2016: Dental Traumatology: Official Publication of International Association for Dental Traumatology
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"