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Dental injurents

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https://www.readbyqxmd.com/read/28105979/human-dental-pulp-stem-cells-are-more-effective-than-human-bone-marrow-derived-mesenchymal-stem-cells-in-cerebral-ischemic-injury
#1
Miyeoun Song, Jae-Hyung Lee, Jinhyun Bae, Youngmin Bu, Eun-Cheol Kim
We compared the therapeutic effects and mechanism of transplanted human dental pulp stem cells (hDPSCs) and human bonemarrow-derived mesenchymal stem cells (hMSCs) in a stroke model of rats and an <i>in vitro</i> ischemic model. Both hDPSCs- and hMSCs- intravenously injected rats 24&#8201;h after middle cerebral artery occlusion showed improved functional recovery and reduced infarct volume versus control rats, but the hDPSCs group showed greater reduction in infarct volume than hMSCs. The positive area for the endothelial cell marker was greater in the lesion boundary areas in the hDPSCs group than with hMSCs...
January 20, 2017: Cell Transplantation
https://www.readbyqxmd.com/read/28049372/operator-related-aspects-in-endodontic-malpractice-claims-in-finland
#2
Miira M Vehkalahti, Outi Swanljung
OBJECTIVE: We analyzed operator-related differences in endodontic malpractice claims in Finland. MATERIALS AND METHODS: Data comprised the endodontic malpractice claims handled at the Patient Insurance Centre (PIC) in 2002-2006 and 2011-2013. Two dental advisors at the PIC scrutinized the original documents of the cases (n = 1271). The case-related information included patient's age and gender, type of tooth, presence of radiographs, and methods of instrumentation and apex location...
January 4, 2017: Acta Odontologica Scandinavica
https://www.readbyqxmd.com/read/28033685/clinical-anatomy-and-surgical-significance-of-the-lingual-foramina-and-their-canals
#3
REVIEW
Puhan He, Mindy K Truong, Nimer Adeeb, R Shane Tubbs, Joe Iwanaga
The lingual foramina and canals can be categorized as medial or lateral based on their relation to the midline of the mandible. Investigation of the mandibular lingual region is often done with gross anatomical dissections of cadavers, 2D panoramic radiographic imaging, CT and cone beam CT (CBCT). While gross studies are the most reliable at qualifying canal contents and course, CBCT proved to be superior to other radiographic techniques for visualizing lingual foramina and canals. The submental and sublingual arteries, and their branches are found in the lingual vascular canals...
December 29, 2016: Clinical Anatomy
https://www.readbyqxmd.com/read/27913866/communicating-branches-between-lingual-and-hypoglossal-nerve-observation-using-sihler-s-staining-technique
#4
Joe Iwanaga, Koichi Watanabe, Tsuyoshi Saga, Yoko Tabira, Moriyoshi Nakamura, Christian Fisahn, R Shane Tubbs, Jingo Kusukawa, Koh-Ichi Yamaki
PURPOSE: Many dental procedures are at risk of injuring the lingual nerve. We performed this study to better elucidate the microanatomy that exists between the ipsilateral lingual and hypoglossal nerves so that iatrogenic injury can be avoided. METHODS: Adult human cadaveric tongues (ten sides) underwent Sihler's staining to identify the microanatomy between the lingual and hypoglossal nerves. RESULTS: The lingual nerve entered the middle part of the anterior two-thirds of the tongue from its lateral side and divided into two to four thick branches...
December 2, 2016: Surgical and Radiologic Anatomy: SRA
https://www.readbyqxmd.com/read/27898626/dental-trauma-in-a-pediatric-emergency-department-referral-center
#5
Emily Hall, Patricia Hickey, Thuy Nguyen-Tran, Jeff Louie
OBJECTIVE: The purpose of this study was to describe dental and associated oral injuries in a pediatric population that presents to an emergency department. METHODS: We performed a retrospective study and identified children from January 2007 to September 2011. Charts were reviewed for any subject, age from newborn to younger than 19 years, based on International Classification of Diseases, Ninth Revision codes for any dental or oral injury. Data abstraction included demographics, time of day of presentation, location and identification of tooth (s) injured, management, and disposition...
December 2016: Pediatric Emergency Care
https://www.readbyqxmd.com/read/27827470/cross-sectional-study-of-dental-trauma-and-associated-factors-among-9-to-14-year-old-schoolchildren-in-isfahan-iran
#6
Faezeh Eslamipour, Pedram Iranmanesh, Ali Borzabadi-Farahani
PURPOSE: To assess the prevalence of dental trauma (DT) and its associated factors in 9- to 14-year-olds. SUBJECTS AND METHODS: A cross-sectional survey was carried out through clinical examination of the permanent incisors and canines of 907 schoolchildren (9 to 14 years old, average age = 11 ± 0.5 [SD] years, 55% female and 45% male) enrolled in 20 public schools in Isfahan, Iran. The demographic data, history and cause of trauma were recorded during patient interviews and with a structured questionnaire filled in by their parents...
2016: Oral Health & Preventive Dentistry
https://www.readbyqxmd.com/read/27703612/occurrence-and-timing-of-complications-following-traumatic-dental-injuries-a-retrospective-study-in-a-dental-trauma-department
#7
Shaul Lin, Nir Pilosof, Munir Karawani, Ronald Wigler, Arieh Y Kaufman, Sorin T Teich
BACKGROUND: This study explores the pattern of complications occurrence resulting from traumatic dental injuries, the relation of this pattern to the number of years from the time of the injury to its first diagnosis, and other contributing characteristics such as root development and trauma characteristic. MATERIAL AND METHODS: Patients' data treated following dental trauma from 2002 to 2014 were classified and grouped according to age, gender, tooth type, injury type, diagnosis and the time that elapsed between the traumatic event and the diagnosis of complications (TIC)...
October 2016: Journal of Clinical and Experimental Dentistry
https://www.readbyqxmd.com/read/27688776/characterization-of-neurogenic-potential-of-dental-pulp-stem-cells-cultured-in-xeno-serum-free-condition-in-vitro-and-in-vivo-assessment
#8
Jieun Jung, Jong-Wan Kim, Ho-Jin Moon, Jin Young Hong, Jung Keun Hyun
Neural stem cells (NSCs) have a high potency for differentiation to neurons and glial cells for replacement of damaged cells and paracrine effects for the regeneration and remyelination of host axons. Dental pulp is known to have a potential to differentiate into neural-like cells; therefore, dental pulp may be used as an autologous cell source for neural repair. In this study, we selectively expanded stem cells from human dental pulp in an initial culture using NSC media under xeno- and serum-free conditions...
2016: Stem Cells International
https://www.readbyqxmd.com/read/27681036/drill-related-root-injury-caused-by-intraoperative-intermaxillary-fixation-an-analysis-of-1067-screw-applications
#9
Stefan Hartwig, Andreas Boettner, Christian Doll, Jan O Voss, Moritz Hertel, Saskia Preissner, Jan D Raguse
BACKGROUND/AIMS: Intermaxillary fixation is a standard procedure for the treatment of mandibular fractures or in orthognathic surgery. Pre-drilling for screws poses the risk of accidental tooth-root injury, potentially leading to further pathological processes. Limited evidence about accidental tooth injury during intermaxillary fixation is available due to heterogenous study designs. The aim of this study was to evaluate the risk of root trauma using pre-drilled transgingival fixation screws and the clinical consequences for the affected teeth...
September 28, 2016: Dental Traumatology: Official Publication of International Association for Dental Traumatology
https://www.readbyqxmd.com/read/27599222/applications-of-platelet-rich-plasma-in-lymphedema
#10
Ahmet Akgül, Musa Cirak, Tansu Birinci
Platelet-rich plasma (PRP) is an autologous concentrated preparation of human platelets contained in a small volume of plasma that is characterized by hemostatic and tissue-repairing effects. Being enriched by various kinds of growth factors, and their tissue-repairing effects have made them the focus of attention for use in tissue regeneration. PRP has been safely used and documented in many different fields, including orthopedics, sports injuries, dental and periodontal surgery, and cosmetic, plastic, cardiovascular, general, and maxillofacial surgery...
December 2016: Lymphatic Research and Biology
https://www.readbyqxmd.com/read/27539194/nerve-growth-factor-secretion-from-pulp-fibroblasts-is-modulated-by-complement-c5a-receptor-and-implied-in-neurite-outgrowth
#11
Fanny Chmilewsky, Warda Ayaz, James Appiah, Imad About, Seung-Hyuk Chung
Given the importance of sensory innervation in tooth vitality, the identification of signals that control nerve regeneration and the cellular events they induce is essential. Previous studies demonstrated that the complement system, a major component of innate immunity and inflammation, is activated at the injured site of human carious teeth and plays an important role in dental-pulp regeneration via interaction of the active Complement C5a fragment with pulp progenitor cells. In this study, we further determined the role of the active fragment complement C5a receptor (C5aR) in dental nerve regeneration in regards to local secretion of nerve growth factor (NGF) upon carious injury...
2016: Scientific Reports
https://www.readbyqxmd.com/read/27537516/a-single-center-retrospective-review-of-post-operative-infectious-complications-in-the-surgical-management-of-mandibular-fractures-post-operative-antibiotics-add-no-benefit
#12
Fernando Domingo, Elizabeth Dale, Cuilan Gao, Cynthia Groves, J Daniel Stanley, Robert A Maxwell, Jimmy L Waldrop
BACKGROUND: Mandibular fractures are common facial injuries and treatment may be complicated by post-operative infection. Risk of infection from contamination with oral flora is well established but no consensus exists regarding antibiotic prophylaxis. The purpose of this study is to assess risk factors and perioperative antibiotics on surgical site infection (SSI) rates following mandibular fracture surgery. METHODS: Retrospective medical record review was completed for trauma patients of any age surgically treated for mandibular fractures at a Level I Trauma Center from September 2006 to June 2012...
August 18, 2016: Journal of Trauma and Acute Care Surgery
https://www.readbyqxmd.com/read/27452795/descriptive-study-of-dental-injury-incurred-by-junior-high-school-and-high-school-students-during-participation-in-school-sports-clubs
#13
Toshiya Nonoyama, Yoshihiro Shimazaki, Haruo Nakagaki, Shinpei Tsuge
AIM: Students often injure their teeth during participation in school-based sports clubs. This study examined the frequencies and types of dental injuries sustained at school sports clubs and compared the risk of dental injury among different sports. METHODS: Based on injury statistics from the Japan Sport Council of the junior high schools and high schools in seven prefectures during fiscal year 2006, the risk of dental injury was estimated using a rate ratio (RR) by calculating the ratio of occurrence of dental injury under various circumstances...
December 2016: International Dental Journal
https://www.readbyqxmd.com/read/27439725/pin1-suppresses-the-hepatic-differentiation-of-pulp-stem-cells-via-wnt3a
#14
H J Kim, Y A Cho, Y M Lee, S Y Lee, W J Bae, E C Kim
This study aimed to investigate the role of PIN1 on the hepatic differentiation of human dental pulp stem cells (hDPSCs) and its signaling pathway, as well as the potential therapeutic effects of hDPSC transplantation and PIN1 inhibition on CCl4 (carbon tetrachloride)-induced liver fibrosis in mice. The in vitro results showed that hepatic differentiation was suppressed by infection with adenovirus-PIN1 and promoted by PIN1 inhibitor juglone via the downregulation of Wnt3a and β-catenin. Compared with treatment with either hDPSC transplantation or juglone alone, the combination of hDPSCs and juglone into CCl4-injured mice significantly suppressed liver fibrosis and restored serum levels of alanine transaminase, aspartate transaminase, and ammonia...
July 20, 2016: Journal of Dental Research
https://www.readbyqxmd.com/read/27418174/antinociceptive-effects-of-botulinum-toxin-type-a-on-trigeminal-neuropathic-pain
#15
K Y Yang, M J Kim, J S Ju, S K Park, C G Lee, S T Kim, Y C Bae, D K Ahn
Previous studies have demonstrated that botulinum toxin type A (BoNT-A) attenuates orofacial nociception. However, there has been no evidence of the participation of the voltage-gated sodium channels (Navs) in the antinociceptive mechanisms of BoNT-A. This study investigated the cellular mechanisms underlying the antinociceptive effects of BoNT-A in a male Sprague-Dawley rat model of trigeminal neuropathic pain produced by malpositioned dental implants. The left mandibular second molar was extracted under anesthesia, followed by a miniature dental implant placement to induce injury to the inferior alveolar nerve...
September 2016: Journal of Dental Research
https://www.readbyqxmd.com/read/27171952/retrieval-of-a-broken-dental-needle-close-to-the-facial-artery-after-cervical-migration
#16
Sormani Bento Fernandes de Queiroz, Valthierre Nunes de Lima, Pedro Henrique Gonçalves Holanda Amorim, Osvaldo Magro-Filho, Rivadávio Fernandes Batista Amorim
Use of imaging tools like digital C-arm, tridimensional tomography, and navigational surgery has proven its value to the surgical removal of broken needles. A 32-year-old patient was referred for evaluation of a fractured needle during inferior alveolar nerve block attempt few days before. The patient complained of a pricking sensation at the injured area while moving the neck. A contrasted computed tomography was performed for further evaluation of the needle toward the vascular network of the neck, showing a close location by the left facial artery, parallel to the styloid process of the temporal bone...
June 2016: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/27168158/retroductal-submandibular-gland-instillation-and-localized-fractionated-irradiation-in-a-rat-model-of-salivary-hypofunction
#17
Renjith Parameswaran Nair, Changyu Zheng, Gulshan Sunavala-Dossabhoy
Normal tissues that lie within the portals of radiation are inadvertently damaged. Salivary glands are often injured during head and neck radiotherapy. Irreparable cell damage results in a chronic loss of salivary function that impairs basic oral activities, and increases the risk of oral infections and dental caries. Salivary hypofunction and its complications gravely impact a patient's comfort. Current symptomatic management of the condition is ineffective, and newer therapies to assuage the condition are needed...
April 24, 2016: Journal of Visualized Experiments: JoVE
https://www.readbyqxmd.com/read/27001780/intra-arterial-infusions-and-doplerograpic-control-for-complex-treatment-of-upper-and-middle-facial-zones-concomitant-with-traumatic-craniocerebral-injuries
#18
G Lagvilava, Z Gvenetadze, E Gibradze, T Danelia, G Gvenetadze
Maxillofacial traumatic injuries concomitant with craniocerebral trauma are still considered as an actual problem in emergency medicine. For this category of patients one of the dangerous and severe complications is development of inflammatory process in the injured areas. Fracture lines of upper and middle facial zones pass through the accessory sinuses of the nose, maxillary/upper dental arch area and are considered to be open and infected fractures. Combination of these fractures with craniocerebral injuries and especially, with open traumas creates predisposition for development of inflammatory processes in CNS that can result in heavy outcome...
February 2016: Georgian Medical News
https://www.readbyqxmd.com/read/26904491/investigation-of-a-pre-clinical-mandibular-bone-notch-defect-model-in-miniature-pigs-clinical-computed-tomography-micro-computed-tomography-and-histological-evaluation
#19
Patricia L Carlisle, Teja Guda, David T Silliman, Wen Lien, Robert G Hale, Pamela R Brown Baer
OBJECTIVES: To validate a critical-size mandibular bone defect model in miniature pigs. MATERIALS AND METHODS: Bilateral notch defects were produced in the mandible of dentally mature miniature pigs. The right mandibular defect remained untreated while the left defect received an autograft. Bone healing was evaluated by computed tomography (CT) at 4 and 16 weeks, and by micro-CT and non-decalcified histology at 16 weeks. RESULTS: In both the untreated and autograft treated groups, mineralized tissue volume was reduced significantly at 4 weeks post-surgery, but was comparable to the pre-surgery levels after 16 weeks...
February 2016: Journal of the Korean Association of Oral and Maxillofacial Surgeons
https://www.readbyqxmd.com/read/26876369/critical-appraisal-comparative-performance-of-mineral-trioxide-aggregate-versus-calcium-hydroxide-as-a-direct-pulp-capping-agent
#20
Steven R Jefferies
Vital pulp therapy is the general concept involved in the "regenerative" restorative treatment of the reversibly injured dental pulp with the intention of maintaining its vitality in a restored, functioning tooth. While this procedure has been attempted with various materials and techniques over a period of several centuries, the advent of hard-setting calcium hydroxide materials in the late 1950s made the procedure of direct pulp capping a more routine and relatively predictable procedure. More recently, in the mid 1990s, a new type of water-based, "hydraulic-type," calcium silicate-based cement, mineral trioxide aggregate (MTA), was introduced to dentistry as a possible alternative to the established standard of hard-setting calcium hydroxide...
March 2016: Journal of Esthetic and Restorative Dentistry
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