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https://www.readbyqxmd.com/read/29330928/specific-labelling-of-myonuclei-by-an-antibody-against-pericentriolar-material-1-pcm1-on-skeletal-muscle-tissue-sections
#1
I M Winje, M Bengtsen, E Eftestøl, I Juvkam, J C Bruusgaard, K Gundersen
AIM: Skeletal muscle is a heterogeneous tissue containing several different cell types and only about 40 - 50% of the cell nuclei within the tissue belong to myofibres. Existing technology, attempting to distinguish myonuclei from other nuclei at the light microscopy level, has led to controversies in our understanding of the basic cell biology of muscle plasticity. The present study aims at demonstrating that an antibody against the protein Pericentriolar material 1 (PCM1) can be used to reliably identify myonuclei on histological cross sections from humans, mice and rats...
January 13, 2018: Acta Physiologica
https://www.readbyqxmd.com/read/29330268/pelvic-and-buttock-hypoplasia-reconstructed-with-anatomical-breast-implants
#2
Felicity Page, Ayad Harb, Garth Titley
Radiation therapy is used in the management of a number of childhood cancers and can have significant effects on skeletal growth. We present the case of a 35-year-old woman who developed a hypoplastic pelvis and buttocks following radiotherapy for rhabdomyosarcoma of the vagina at the age of 2. At the age of 25, the patient underwent bilateral buttock augmentation with a two-stage reconstruction using tissue expansion followed by definitive augmentation with anatomical breast implant insertion. The patient continues to have a satisfactory outcome 10 years following reconstruction, having undergone a single uplift procedure and exchange of implants through the original incision 9 years postoperatively...
January 12, 2018: BMJ Case Reports
https://www.readbyqxmd.com/read/29328534/split-thickness-skin-grafting-for-reconstruction-of-auricular-skin-defects-a-statistical-analysis
#3
Tobias Thuile, Lorenz Larcher, Barbara Gatscher, Karl Schwaiger, Jenny Deluca, Amgiad Fallaha, Lukas Tappeiner, Mario Puviani, Klaus Eisendle
BACKGROUND AND OBJECTIVES: Surgical reconstruction following the removal of large malignant auricular lesions is challenging. While many options for defect closure have been described, in the elderly population usually affected flap surgery, long anesthesia times, patient compliance, and anticoagulant therapy pose additional risks. An alternative quick, simple, and effective method of defect closure is therefore highly desirable. The objective of the present study was to assess the aesthetic outcome, healing process, complications, and recurrence rates associated with unmeshed split-thickness skin grafts (STSGs) used for covering large auricular skin defects following cartilage-sparing skin cancer removal...
January 12, 2018: Journal der Deutschen Dermatologischen Gesellschaft, Journal of the German Society of Dermatology: JDDG
https://www.readbyqxmd.com/read/29328523/improved-portal-vein-venoplasty-with-autogenous-patch-in-pediatric-living-donor-liver-transplantation
#4
Mingxuan Feng, Ping Wan, Bijun Qiu, Tao Zhou, Yi Luo, Lihong Gu, Jiachang Chi, Chengpeng Zhong, Yefeng Lu, Jianjun Zhang, Qiang Xia
BACKGROUND: An atretic or hypoplastic portal vein (PV) represents a challenge for PV reconstruction in pediatric living donor liver transplantation (LDLT). Several PV venoplastic techniques have been developed. However, we still seek improved venoplastic techniques with better efficacy and compatibility. METHOD: From June 2016 to July 2017, 271 LDLT procedures were performed at the Department of Liver Surgery, Ren Ji Hospital. A total of 16 consecutive children with atretic and sclerotic PVs underwent a novel technique - the autogenous PV patch plastic technique...
January 12, 2018: Liver Transplantation
https://www.readbyqxmd.com/read/29325808/dutch-breast-reconstruction-guideline
#5
REVIEW
Marc A M Mureau
Treatment of breast cancer is complex and multidisciplinary by nature, with protocols that are updated continuously. During preoperative multidisciplinary team meetings, regularly there is discussion between team members regarding optimal timing and type of breast reconstruction, due to conflicting interests of oncological and reconstructive treatments. Therefore, a multidisciplinary, evidence-based guideline for breast reconstruction in women undergoing breast conserving therapy or mastectomy for breast cancer, or following prophylactic mastectomy was developed by a multidisciplinary working group...
December 27, 2017: Journal of Plastic, Reconstructive & Aesthetic Surgery: JPRAS
https://www.readbyqxmd.com/read/29325183/validation-of-the-modified-surgeon-periorbital-rating-of-edema-and-ecchymosis-spree-questionnaire-a-prospective-analysis-of-facial-plastic-and-reconstructive-surgery-procedures
#6
Jeremie D Oliver, Deanna Menapace, Ahmed Younes, Chelsey Recker, Grant Hamilton, Oren Friedman
Although periorbital edema and ecchymosis are commonly encountered after facial plastic and reconstructive surgery procedures, there is currently no validated grading scale to qualify these findings. In this study, the modified "Surgeon Periorbital Rating of Edema and Ecchymosis (SPREE)" questionnaire is used as a grading scale for patients undergoing facial plastic surgery procedures. This article aims to validate a uniform grading scale for periorbital edema and ecchymosis using the modified SPREE questionnaire in the postoperative period...
January 11, 2018: Facial Plastic Surgery: FPS
https://www.readbyqxmd.com/read/29324933/brachytherapy-in-soft-tissue-tumours-an-interdisciplinary-challenge
#7
Silvanie Volz, Konstantinos Kalousis, Jung In Song, Tobias Kisch, Eike Wenzel, Peter Mailänder
OBJECTIVE: Interdisciplinary work including surgery and additive radiotherapy is often needed for the therapy of tumours. Beneath this, brachytherapy is an important part of the radiotherapy. It was first used over 100 years ago and is in regular use after the development of afterload technology in the early 1970s. Today it is often used in different tumour therapies, for example in soft tissue sarcoma or breast tumours, in order to decrease the risk of local recurrence. Concerning its benefits, higher doses could be used because of the localized effect with equivalent local control rate and less toxicity of treatment...
September 2017: Hellenic Journal of Nuclear Medicine
https://www.readbyqxmd.com/read/29323728/3d-reconstruction-of-prostate-cancer-architecture-with-serial-immunohistochemical-sections-hallmarks-of-tumour-growth-tumour-compartmentalization-and-implications-for-grading-and-heterogeneity
#8
Yuri Tolkach, Stefan Thomann, Glen Kristiansen
BACKGROUND: Conventional morphology of the prostate cancer (PCA) considers only two-dimensional architecture of the tumour. Our aim was to examine the feasibility of 3D-reconstruction of tumour morphology based on multiple consecutive histological sections and to decipher relevant features of PCA architecture. METHODS: Seventy-five consecutive histological sections (5μm) of a typical prostate adenocarcinoma (Gleason-Score 3+4=7) were immunostained (Pan-Cytokeratin) and scanned for further 3D reconstructions with Fiji / ImageJ software...
January 11, 2018: Histopathology
https://www.readbyqxmd.com/read/29322847/tissue-expanders-with-a-focus-on-extremity-reconstruction
#9
Abdul R Arain, Keegan Cole, Christopher Sullivan, Samik Banerjee, Jillian Kazley, Richard L Uhl
Acute traumatic or surgical wounds that cannot be primarily closed often cause substantial morbidity and mortality. This often leads to increased costs from higher material expenses, more involved nursing care, and longer hospital stays. Advancements in soft tissue expansion has made it a popular alternative to facilitate early closure without the need for more complicated plastic surgical procedures. Areas Covered: In this review, we briefly elaborate on the history and biomechanics of tissue expansion and provide comprehensive descriptions of traditional internal tissue expanders and a variety of contemporary external tissue expanders...
January 11, 2018: Expert Review of Medical Devices
https://www.readbyqxmd.com/read/29321886/gap-formation-and-dynamics-after-long-term-steady-state-in-an-old-growth-picea-abies-stand-in-norway-above-and-belowground-interactions
#10
Per Holm Nygaard, Line Tau Strand, Arne Oddvar Stuanes
Stand dynamics and the gap initiation prior to gap formation are not well-understood because of its long-term nature and the scarcity of late-successional stands. Reconstruction of such disturbance is normally based on historical records and dendroecological methods. We investigated gap initiation and formation at the fine-scale stand level in the old-growth reserve of Karlshaugen in Norway. Given its long-term conservation history, and thorough mapping in permanent marked plots with spatially referenced trees, it provides an opportunity to present stand development before, during, and after gap formation...
January 2018: Ecology and Evolution
https://www.readbyqxmd.com/read/29312715/multidisciplinary-approach-to-chest-wall-resection-and-reconstruction-for-chest-wall-tumors-a-single-center-experience
#11
Elisa Scarnecchia, Valeria Liparulo, Alessandra Pica, Giuseppe Guarro, Carmine Alfano, Francesco Puma
Background: Chest wall resection and reconstruction (CWRR) is quite challenging in surgery, due to evolution in techniques. Neoplasms of the chest wall, primary or secondary, have been considered inoperable for a long time. Thanks to evolving surgical techniques, reconstruction after extensive chest wall resection is possible with good functional and aesthetic results. Methods: In our single-center experience, seven cases of extensive CWRR for tumors were performed with a multidisciplinary approach by both thoracic and plastic surgeons...
December 2017: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/29311019/the-ideal-ear-position-in-caucasian-females
#12
P Niclas Broer, Aung Thiha, Denis Ehrl, Sammy Sinno, Sabrina Juran, Caroline Szpalski, Reuben Ng, Milomir Ninkovic, Lukas Prantl, Paul I Heidekrueger
PURPOSE: Ear position contributes significantly to facial appearance. However, while objective measurements remain the foundation for esthetic evaluations, little is known about how an ear should ideally be positioned regarding its rotational axis. This study aimed to further evaluate whether there exists a universally applicable ideal ear axis, and how sociodemographic factors impact such preferences. MATERIALS AND METHODS: An interactive online survey was designed, enabling participants to change the axis of a female model's ear in terms of its forward and backward rotation...
December 26, 2017: Journal of Cranio-maxillo-facial Surgery
https://www.readbyqxmd.com/read/29308257/the-genus-gennadas-benthesicymidae-decapoda-morphology-of-copulatory-characters-phylogeny-and-coevolution-of-genital-structures
#13
Alexander L Vereshchaka, Anastasia A Lunina, Jørgen Olesen
Species within Gennadas differ from each other largely only in male (petasma) and female (thelycum) copulatory characters, which were restudied in scanning electron microscopy and used as a basis for phylogenetic analyses. Twenty-six petasma characters and 49 thelycum characters were identified. All 16 recognized species of Gennadas and Aristaeomorpha foliacea (outgroup) were included as terminals. Four robust monophyletic clades were retrieved, described and diagnosed as new species groups. The thelycum characters had greater impact on tree topology and supported deeper nodes than did the petasma characters...
December 2017: Royal Society Open Science
https://www.readbyqxmd.com/read/29304515/the-prevalence-of-cosmetic-facial-plastic-procedures-among-facial-plastic-surgeons
#14
Roxana Moayer, Jordan P Sand, Albert Han, Vishad Nabili, Gregory S Keller
This is the first study to report on the prevalence of cosmetic facial plastic surgery use among facial plastic surgeons. The aim of this study is to determine the frequency with which facial plastic surgeons have cosmetic procedures themselves. A secondary aim is to determine whether trends in usage of cosmetic facial procedures among facial plastic surgeons are similar to that of nonsurgeons. The study design was an anonymous, five-question, Internet survey distributed via email set in a single academic institution...
January 5, 2018: Facial Plastic Surgery: FPS
https://www.readbyqxmd.com/read/29303863/unusual-craniofacial-distraction
#15
Aina V H Greig, Court B Cutting, Jamie Levine, Barry Grayson, Joseph G McCarthy
A retrospective Institutional Review Board-approved review was performed at the Institute of Reconstructive Plastic Surgery, NYU Langone Medical Center, of patients undergoing craniofacial distraction osteogenesis procedures using the rigid external distractor device between 2000 and 2010. Three particularly challenging cases were identified and are presented here.
January 4, 2018: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/29301014/pedicled-vascularized-bone-grafts-for-posterior-occipitocervical-and-cervicothoracic-fusion-a-cadaveric-feasibility-study
#16
Michael A Bohl, Michael A Mooney, Joshua S Catapano, Kaith K Almefty, Jay D Turner, Steve W Chang, Mark C Preul, Edward M Reece, U Kumar Kakarla
BACKGROUND: Arthrodesis is critical for achieving favorable outcomes in reconstructive spine surgery. Vascularized bone grafts (VBGs) have been successfully used to augment fusion rates in a variety of skeletal pathologies, and pedicled VBG has numerous advantages over free transfer VBG. Pedicled VBG has not previously been described for the posterior occipitocervicothoracic spine. OBJECTIVE: To identify, describe, and assess potential donor sites for pedicled VBGs from occiput to T12 using a cadaver model and to describe important technical considerations for graft harvest and placement...
December 30, 2017: Operative Neurosurgery (Hagerstown, Md.)
https://www.readbyqxmd.com/read/29300514/surgical-preferences-in-the-management-of-recalcitrant-endophthalmitis
#17
Roxana Fu, Joseph Childs, William Nunery, Peter Timoney
To assess the practice patterns of current members of the American Society of Ophthalmic Plastic and Reconstructive Surgery (ASOPRS) in the treatment of medically refractive endophthalmitis (MRE). A 17-question survey included the procedure of choice for MRE, the preferred type of orbital implant, the timing of implant placement, and the incidence of postoperative complications. 107 ASOPRS members participated in the study. In the setting of MRE, 72% preferred evisceration versus 28% who preferred enucleation...
January 4, 2018: Orbit
https://www.readbyqxmd.com/read/29300183/improved-proton-ct-imaging-using-a-bismuth-germanium-oxide-scintillator
#18
Sodai Tanaka, Teiji Nishio, Masato Tsuneda, Keiichiro Matsushita, Shigeto Kabuki, Mitsuru Uesaka
Range uncertainty is among the most formidable challenges associated with the treatment planning of proton therapy. Proton imaging, which includes proton radiography (pRG) and proton computed tomography (pCT), is a useful verification tool. We have developed a pCT detection system that uses a thick bismuth germanium oxide (BGO) scintillator and a CCD camera. The current method is based on a previous detection system that used a plastic scintillator, and implements improved image processing techniques. In the new system, the scintillation light intensity is integrated along the proton beam path by the BGO scintillator, and acquired as a two-dimensional distribution with the CCD camera...
January 4, 2018: Physics in Medicine and Biology
https://www.readbyqxmd.com/read/29290464/complex-upper-arm-reconstruction-using-an-antero-lateral-thigh-free-flap-after-an-extravasation-of-yttrium-90-ibritumomab-tiuxetan-a-case-report-and-literature-review
#19
A Baus, C Keilani, C-S Bich, F Entine, M Brachet, P Duhamel, J-C Amabile, J V Malfuson, E Bey
Yttrium-90-Ibritumomab Tiuxetan (Zevalin®) is used in the treatment of non- Hodgkin's lymphoma. Extravasation is an iatrogenic complication that is fortunately rare. However, the treatment of this complication is often complex due to the risk of extensive skin necrosis and unpredictable evolution of localized irradiation. This vesicant drug requires emergency management when extravasation occured. Radiations burns have specificities. Therefore, wound coverage involves specific plastic surgical techniques. Here, we report the case of a man presenting a chronic and extensive skin necrosis of upper arm treated with an antero-lateral thigh free flap...
December 28, 2017: Annales de Chirurgie Plastique et Esthétique
https://www.readbyqxmd.com/read/29287289/-current-german-and-american-guidelines-for-autologous-fat-grafting-a-transatlantic-comparison
#20
G Felix Broelsch, Sören Könneker, Ramin Ipaktchi, Peter M Vogt
CLINICAL PROBLEM: The renewed clinical interest in fat grafting for both reconstructive and aesthetic purposes prompted the American Society of Plastic Surgeons to establish a Fat Graft Task Force (AFGT) in 2009. Moreover, in 2015, the German Society of Plastic, Reconstructive and Aesthetic Surgeons (DGPRÄC), in cooperation with three relevant medical societies (DDG, DGMKG, DGGG), formulated statements on the provision of strategies for patient management and to guide physicians in clinical decision making, on the basis of the scientific literature, clinical experience and current laws...
December 2017: Handchirurgie, Mikrochirurgie, Plastische Chirurgie
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