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https://www.readbyqxmd.com/read/27559444/ankylosing-spondylitis-patterns-of-spinal-injury-and-treatment-outcomes
#1
Idiris Altun, Kasım Zafer Yuksel
STUDY DESIGN: Retrospective review. PURPOSE: We retrospectively reviewed our patients with ankylosing spondylitis (AS) to identify their patterns of spinal fractures to help clarify management strategies and the morbidity and mortality rates associated with this group of patients. OVERVIEW OF LITERATURE: Because of the brittleness of bone and long autofused spinal segments in AS, spinal fractures are common even after minor trauma and often associated with overt instability...
August 2016: Asian Spine Journal
https://www.readbyqxmd.com/read/27502236/conversion-of-ankle-autofusion-to-total-ankle-replacement-using-the-salto-xt-revision-prosthesis
#2
Emilie R C Williamson, Constantine A Demetracopoulos, Scott J Ellis
Few reports in the literature have described the conversion of a surgically fused ankle to a total ankle replacement. The takedown of an autofusion and conversion to a prosthesis has not been described. We report the case of a patient with severe rheumatoid arthritis with an ankle autofusion fixed in equinus and severe talonavicular arthritis that was converted to ankle replacement using the Salto XT revision system. We describe the reasons why the decision was made to perform total ankle arthroplasty while concomitantly fusing the talonavicular joint, and discuss the rationale of the various surgical treatment options considered...
September 2016: Foot and Ankle Surgery: Official Journal of the European Society of Foot and Ankle Surgeons
https://www.readbyqxmd.com/read/27432429/long-term-management-of-congenital-lordoscoliosis-of-the-thoracic-spine
#3
Kee-Yong Ha, Seung-Woo Suh, Young-Hoon Kim, Sang-Il Kim
PURPOSE: The objective of this study is to report the progression of congenital hyperlordoscoliosis in a 2-year-old patient and the use of multiple surgical interventions in the treatment of hyperlordoscoliosis of the thoracic spine. METHODS: A 2-year-old patient with thoracic hyperlordosis underwent observation for 1 year. To halt the progression of hyperlordosis, a posterior laminectomy was carried out to remove all the fused segments. Despite surgery, lordosis progressed via spontaneous autofusion with development of scoliosis with unilateral unsegmented bar...
July 18, 2016: European Spine Journal
https://www.readbyqxmd.com/read/27327930/silicone-arthroplasty-after-ankylosis-of-proximal-interphalangeal-joints-in-rheumatoid-arthritis-a-case-report
#4
Hisham M Awan, Joseph E Imbriglia
Rheumatoid arthritis (RA) can cause severe disability of the hand and fingers. Ankylosis of the finger joints is a known yet underreported manifestation of RA of the hand. We report the case of a patient who had RA and developed autofusion of the proximal interphalangeal (PIP) joints. At presentation, the PIP joints were fused in 15° of flexion. Silicone PIP arthroplasty was performed. Function improved with 60° of PIP joint motion and no pain.
May 2016: American Journal of Orthopedics
https://www.readbyqxmd.com/read/27196004/treatment-of-early-onset-spinal-deformity-eosd-with-veptr-a-challenge-for-the-final-correction-spondylodesis-a-case-series
#5
Friederike Lattig, Rita Taurman, Anna K Hell
STUDY DESIGN: Case Series. OBJECTIVE: To describe the post-VEPTR (vertical expandable prosthetic titanium rib) treatment changes in early-onset spinal deformity (EOSD), which may influence the final correction spondylodesis. SUMMARY OF BACKGROUND DATA: The VEPTR device, originally developed for the treatment of congenital rib cage malformation, is nowadays more widely used in the treatment of EOSD. At present, only a few reports describe the possible complications that may occur with repeated lengthening procedures of the VEPTR, thereby making the final spondylodesis more complicated and less satisfactory...
June 2016: Clinical Spine Surgery
https://www.readbyqxmd.com/read/26993327/genetic-composition-of-interspecific-potato-somatic-hybrids-and-autofused-4x-plants-evaluated-by-dart-and-cytoplasmic-dna-markers
#6
Paulina Smyda-Dajmund, Jadwiga Śliwka, Iwona Wasilewicz-Flis, Henryka Jakuczun, Ewa Zimnoch-Guzowska
Using DArT analysis, we demonstrated that all Solanum × michoacanum (+) S. tuberosum somatic hybrids contained all parental chromosomes. However, from 13.9 to 29.6 % of the markers from both parents were lost in the hybrids. Somatic hybrids are an interesting material for research of nucleus-cytoplasm interaction and sources of new nuclear and cytoplasmic combinations. Analyses of genomes of somatic hybrids are essential for studies on genome compatibility between species, its evolution and are important for their efficient exploitation...
June 2016: Plant Cell Reports
https://www.readbyqxmd.com/read/26513429/management-of-spinal-fractures-in-patients-with-ankylosing-spondylitis
#7
REVIEW
Najib E El Tecle, Kingsley O Abode-Iyamah, Patrick W Hitchon, Nader S Dahdaleh
Ankylosing spondlylitis is a seronegative spondyloarthropathy that primarily affects the spinal column and sacroiliac joints. With disease progression autofusion of the spinal column takes place. This combined with the brittle bone quality make patients prone to fractures and spinal cord injury. The typical fracture pattern is extension type and involves all three columns. These fractures and injuries may involve the craniovertebral junction, the subaxial cervical spine, and the thoracolumbar spine. While at times these fractures are challenging to manage especially when they affect the elderly, there is evidence that supports long segment fixation and fusion...
December 2015: Clinical Neurology and Neurosurgery
https://www.readbyqxmd.com/read/26128065/su-e-t-402-evaluation-of-the-accuracy-of-a-novel-open-mask-system-for-immobilization-of-cranial-stereotactic-radiosurgery-patients
#8
K Song, N Wen, Y Qin, J Kim, H Li, K Snyder, J Gordon, I Chetty, S Siddiqui
PURPOSE: To evaluate the accuracy of a novel open mask for intracranial SRS and to investigate the capability of monitoring intrafraction motion of the patient within this mask using the optical surface monitoring system (OSMS) on a linac-based platform. METHODS: Efficiency was evaluated by measuring mask fabrication time during CT simulation and setup time in the treatment room. Mask shrinkage was assessed by comparing shim settings during treatment to simulation and also by measuring the distance between anterior and posterior sections of the mask on CBCT and Sim CT...
June 2015: Medical Physics
https://www.readbyqxmd.com/read/25701769/basilar-invagination-case-report-and-literature-review
#9
REVIEW
Nauman S Chaudhry, Alp Ozpinar, Wenya Linda Bi, Vamsidhar Chavakula, John H Chi, Ian F Dunn
BACKGROUND: Basilar invagination is a rare clinical condition characterized by upward protrusion of the odontoid process into the intracranial space, leading to bulbomedullary compression. It is often encountered in adults with rheumatoid arthritis. Transoral microscopic or endonasal endoscopic decompression may be pursued, with or without posterior fixation. We present a case of basilar invagination with C1-C2 autofusion and discuss an algorithm for choice of anterior versus posterior approaches...
June 2015: World Neurosurgery
https://www.readbyqxmd.com/read/24981908/traumatic-thoracolumbar-spinal-injury-an-algorithm-for-minimally-invasive-surgical-management
#10
REVIEW
Sanjay S Dhall, Rishi Wadhwa, Michael Y Wang, Alexandra Tien-Smith, Praveen V Mummaneni
OBJECT: Minimally invasive spinal (MIS) surgery techniques have been used sporadically in thoracolumbar junction trauma cases in the past 5 years. A review of the literature on the treatment of thoracolumbar trauma treated with MIS surgery revealed no unifying algorithm to assist with treatment planning. Therefore, the authors formulated a treatment algorithm. METHODS: The authors reviewed the current literature on MIS treatment of thoracolumbar trauma. Based on the literature review, they then created an algorithm for the treatment of thoracolumbar trauma utilizing MIS techniques...
2014: Neurosurgical Focus
https://www.readbyqxmd.com/read/23525760/development-of-somatic-hybrids-solanum%C3%A2-%C3%A3-%C3%A2-michoacanum-bitter-rydb-s-tuberosum-l-and-autofused-4x-s-%C3%A2-%C3%A3-%C3%A2-michoacanum-plants-as-potential-sources-of-late-blight-resistance-for-potato-breeding
#11
P Smyda, H Jakuczun, K Dębski, J Sliwka, R Thieme, M Nachtigall, I Wasilewicz-Flis, E Zimnoch-Guzowska
Phytophthora infestans resistant somatic hybrids of S. × michoacanum (+) S. tuberosum and autofused 4 x S. × michoacanum were obtained. Our material is promising to introgress resistance from S. × michoacanum into cultivated potato background. Solanum × michoacanum (Bitter.) Rydb. (mch) is a wild diploid (2n = 2x = 24) potato species derived from spontaneous cross of S. bulbocastanum and S. pinnatisectum. This hybrid is a 1 EBN (endosperm balance number) species and can cross effectively only with other 1 EBN species...
August 2013: Plant Cell Reports
https://www.readbyqxmd.com/read/22358761/increased-production-of-recombinant-higfbp-1-in-peg-induced-autofusion-of-chinese-hamster-ovary-cho-cells
#12
C Dyring
A recombinant Chinese hamster ovary (CHO) cell clone, S1, stably expressing human insulin-like growth factor binding protein-1 (hIGFBP-1), was treated with polyethylene glycol (PEG), resulting in cell fusion, in order to further enhance the protein expression by increasing the gene copy number and/or the amount of organelles important to the protein expression/-secretion. Both the fused cell line, Peg1, and its mother cell line, S1, were adapted to serum-free growth in suspension and were characterised with respect to growth and productivity...
September 1997: Cytotechnology
https://www.readbyqxmd.com/read/21235305/biomechanical-analysis-of-cervicothoracic-junction-osteotomy-in-cadaveric-model-of-ankylosing-spondylitis-effect-of-rod-material-and-diameter
#13
Justin K Scheer, Jessica A Tang, Vedat Deviren, Frank Acosta, Jenni M Buckley, Murat Pekmezci, R Trigg McClellan, Christopher P Ames
OBJECT: Ankylosing spondylitis (AS) is a genetic condition that frequently results in spinal sagittal plane deformity of thoracolumbar or cervicothoracic junctions. Generally, a combination of osteotomy and spinal fixation is used to treat severe cases. Although surgical techniques for traumatic injury across the cervicothoracic junction have been well characterized in clinical and biomechanical literature, the specific model of instrumented opening wedge osteotomy in autofused AS has not been studied biomechanically...
March 2011: Journal of Neurosurgery. Spine
https://www.readbyqxmd.com/read/20683383/autofusion-in-the-immature-spine-treated-with-growing-rods
#14
REVIEW
Patrick J Cahill, Sean Marvil, Laury Cuddihy, Corey Schutt, Jocelyn Idema, David H Clements, M Darryl Antonacci, Jahangir Asghar, Amer F Samdani, Randal R Betz
STUDY DESIGN: Retrospective case review of skeletally immature patients treated with growing rods. Patients received an average of 9.6 years follow-up care. OBJECTIVE: (1) to identify the rate of autofusion in the growing spine with the use of growing rods; (2) to quantify how much correction can be attained with definitive instrumented fusion after long-term treatment with growing rods; and (3) to describe the extent of Smith-Petersen osteotomies required to gain correction of an autofused spine following growing rod treatment...
October 15, 2010: Spine
https://www.readbyqxmd.com/read/20448153/the-fusogen-eff-1-controls-sculpting-of-mechanosensory-dendrites
#15
Meital Oren-Suissa, David H Hall, Millet Treinin, Gidi Shemer, Benjamin Podbilewicz
The mechanisms controlling the formation and maintenance of neuronal trees are poorly understood. We examined the dynamic development of two arborized mechanoreceptor neurons (PVDs) required for reception of strong mechanical stimuli in Caenorhabditis elegans. The PVDs elaborated dendritic trees comprising structural units we call "menorahs." We studied how the number, structure, and function of menorahs were maintained. EFF-1, an essential protein mediating cell fusion, acted autonomously in the PVDs to trim developing menorahs...
June 4, 2010: Science
https://www.readbyqxmd.com/read/19238097/giant-cervical-exostosis-a-case-report-with-review-of-literature
#16
Harish Rao, Subhash Jakheria
We report a rare case of an 8-year-old girl who presented with a giant cauliflower-like autofused pedunculated osteochondroma arising from spinous processes of the second to sixth cervical vertebrae. She was successfully treated by enbloc excision without any recurrence.
March 2009: Journal of Pediatric Orthopedics. Part B
https://www.readbyqxmd.com/read/18260500/spontaneous-kyphotic-collapse-followed-by-autostabilisation-secondary-to-cervical-osteomyelitis-in-an-intravenous-drug-abuser
#17
Ranganathan Arun, Anand Vijay Kasbekar, S M Hossein Mehdian
There is a high risk of cervical osteomyelitis in intravenous drug abusers due to the use of jugular veins for administration of drugs. Here described is a case of rapid vertebral body destruction at two levels leading to a progressive kyphotic deformity followed by autofusion, secondary to cervical osteomyelitis. The case report goes on to hypothesise about the unique manner of progression of untreated cervical osteomyelitis with a rapid onset of kyphotic deformity and associated severe bone destruction in an intravenous drug abuser...
December 2007: Acta Orthopaedica Belgica
https://www.readbyqxmd.com/read/17849033/autofusion-of-the-cervical-spine-in-2-children-following-open-biopsy-of-langerhans-cell-histiocytosis
#18
Sumeet Garg, Harish Hosalkar, John P Dormans
No abstract text is available yet for this article.
August 2007: American Journal of Orthopedics
https://www.readbyqxmd.com/read/15644748/a-case-report-of-severe-kyphoscoliosis-and-autofusion-of-the-posterior-elements-in-two-siblings-with-central-core-disease
#19
Anthony M Sestero, Joseph H Perra
STUDY DESIGN: A case report of two siblings (ages 14 and 17 years) with central core disease and prior malignant hyperthermia successfully treated with spinal fusion surgery for severe kyphoscoliosis. OBJECTIVES: Our objectives were as follows: to describe the previously unreported findings of posterior element autofusion and ligamentum flavum ossification; to increase surgeon awareness to the nature of this condition and associated findings; and to prepare the surgeons for the possibility of autofusion and the required surgical modifications, including extensive osteotomies at the time of spinal fusion surgery to achieve correction based on these findings...
January 15, 2005: Spine
https://www.readbyqxmd.com/read/10710146/spontaneous-interbody-fusion-after-controlled-injuries-to-the-spine-an-experimental-study-in-rabbits
#20
D S Korres, G C Babis, H Paraskevakou, K Stamos, J Tsarouchas, V Lykomitros
To evaluate the rationale of spontaneous spine fusion after a spinal injury, the authors conducted an experimental study that consisted of three types of controlled injuries to a rabbit spine model. The first was injury to the intervertebral disk (type I injury). The second was injury of the intervertebral disk along with injury to one of the adjacent vertebral end plates (type II). In type III injury, both the opposing end plates were injured along with the intervertebral disk. In 38 rabbits, a total of 82 injuries of these three types were inflicted...
February 2000: Journal of Spinal Disorders
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