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https://www.readbyqxmd.com/read/29793156/mechanical-properties-of-the-human-scalp-in-tension
#1
Lisa Falland-Cheung, Mario Scholze, Pamela F Lozano, Benjamin Ondruschka, Darryl C Tong, Paul A Brunton, J Neil Waddell, Niels Hammer
Mechanical properties of the human scalp have not been investigated to a great extent with limited information available. The purpose of this study was to provide new baseline material data for human scalp tissue of various ages, which can be applied to experimental and constitutive models, such as in the area of impact biomechanics. This study used specimens from the left and right temporal, fronto-parietal and occipital regions of the human scalp. It investigated the tensile behavior of scalp tissue using tissues harvested from unfixed, fresh cadavers...
May 17, 2018: Journal of the Mechanical Behavior of Biomedical Materials
https://www.readbyqxmd.com/read/29792867/effects-of-amphetamine-exposure-during-adolescence-on-behavior-and-prelimbic-cortex-neuron-activity-in-adulthood
#2
Luke K Sherrill, Joshua M Gulley
Repeated exposure to psychostimulants during adolescence produces long-lasting changes in behavior that may be mediated by disrupted development of the mesocorticolimbic dopamine system. Here, we tested this hypothesis by assessing the effects of amphetamine (AMPH) and dopamine receptor-selective drugs on behavior and neuron activity in the prelimbic region of the medial prefrontal cortex (PFC). Adolescent male, Sprague-Dawley rats were given saline or 3 mg/kg AMPH between postnatal day (P) 27 and P45. In Experiment 1, locomotor behavior was assessed during adulthood following challenges with a dopamine D1 (SKF 82958) or D2 (quinpirole) receptor-selective agonist...
May 21, 2018: Brain Research
https://www.readbyqxmd.com/read/29792499/teacher-and-student-race-as-a-predictor-for-negative-feedback-during-instruction
#3
Terrance M Scott, Nicholas Gage, Regina Hirn, HyunSuk Han
There is a long and persistent gap between the academic achievement of White and Black students in America's schools. Further, Black students are suspended from school at a rate that is more than three times greater than White students. While there has been some suggestion that perhaps teacher-student racial matching may be part of a solution, the research does not currently provide adequate support for teacher race alone to be sufficiently effective. This study analyzed 41 Black and White teacher-student dyad mixes in elementary schools and another 41 in a high school to examine how teacher and student race interact in terms of teacher and student behaviors...
May 24, 2018: School Psychology Quarterly
https://www.readbyqxmd.com/read/29791456/multi-species-suppression-of-herbivores-through-consumptive-and-non-consumptive-effects
#4
Kathryn S Ingerslew, Deborah L Finke
Most studies investigating the importance of non-consumptive interactions for herbivore suppression focus on pairwise interactions between one predator and one prey, ignoring any community context. Further, the potential for non-consumptive interactions to arise between herbivores and non-enemy organisms is commonly overlooked. We investigated the relative contributions of consumptive and non-consumptive effects to aphid suppression by a wasp assemblage containing both enemies and non-enemies. We examined the suppression of two aphid species with different defensive strategies, pea aphids (Acyrthosiphon pisum), which drop from their host plant to the ground, and green peach aphids (Myzus persicae), which remain on the plant and merely walk away...
2018: PloS One
https://www.readbyqxmd.com/read/29789859/fibrous-dysplasia-an-unusual-case-of-a-very-aggressive-form-with-costo-vertebral-joint-destruction-and-invasion-of-the-contralateral-d7-vertebral-body
#5
Carmine Zoccali, Dario Attala, Barbara Rossi, Giovanni Zoccali, Virginia Ferraresi
Fibrous dysplasia (FD) is a benign fibro-osseous disease of the bone that may be solitary or multicentric. It is important to distinguish this type of lesion from low-grade osteosarcomas (LGOS) and from secondary sarcomas, because malignant transformation has rarely been reported. It is classically described as having a ground-glass appearance, endosteal scalloping, and thinning of the cortex. Cortical disruption is considered evidence of malignancy, but it can also be present in benign FD with aggressive behavior...
May 23, 2018: Skeletal Radiology
https://www.readbyqxmd.com/read/29788185/cyclophosphamide-induced-disruptions-to-appetitive-qualities-and-detection-thresholds-of-nacl-comparison-of-single-dose-and-dose-fractionation-effects
#6
Benjamin C Jewkes, Michael G Gomella, Evan T Lowry, Joy A Benner, Eugene R Delay
Chemotherapy is one of the most common treatments for cancer, however a side effect is often altered taste. This study examined how cyclophosphamide, a chemotherapy drug, affects salt taste in mice. Based on previous findings, it was predicted that cyclophosphamide-induced disruptions in salt taste would be observed near days 2-4, 8-12, and 22-24 days post treatment, and that multiple, smaller doses would cause more severe disruptions to taste. To test these predictions, two experiments were performed, one using brief access testing to measure appetitive qualities, and another using operant conditioning to measure detection thresholds...
May 19, 2018: Chemical Senses
https://www.readbyqxmd.com/read/29787829/social-reward-and-social-punishment-sensitivity-in-relation-to-dietary-restraint-and-binge-purge-symptoms
#7
Lauren M Fussner, Aaron M Luebbe, April R Smith
Disordered eating symptoms are associated with disrupted sensitivity to reward and punishment, broadly assessed. However, it is unknown how eating pathology is related to sensitivity to social reward and social punishment specifically. Drawing on Reinforcement Sensitivity Theory, the current study utilized a multi-method design to test whether disordered eating symptoms, specifically dietary restraint (DR) and binge/purge (BP), were similarly or uniquely related to sensitivity to social punishment and social reward...
May 19, 2018: Appetite
https://www.readbyqxmd.com/read/29787691/the-influence-of-spinal-cord-injury-on-breastfeeding-ability-and-behavior
#8
Theodor Holmgren, Amanda H X Lee, Shea Hocaloski, Lynsey J Hamilton, Iris Hellsing, Stacy Elliott, Claes Hultling, Andrei V Krassioukov
BACKGROUND: Lactation dysfunction following spinal cord injury has been noted in the literature. However, researchers have often grouped together all women of physical disability or do not account for injury level. The extent of lactation dysfunction and influence of spinal cord injury on breastfeeding ability and behavior is not well understood. Research aim: This study aimed to identify major barriers to lactation and breastfeeding related to spinal cord injury, specifically comparing high- and low-level injuries...
May 1, 2018: Journal of Human Lactation: Official Journal of International Lactation Consultant Association
https://www.readbyqxmd.com/read/29786067/disrupting-reconsolidation-memory-erasure-or-blunting-of-emotional-motivational-value
#9
Elizabeth S Cogan, Mark A Shapses, Terry E Robinson, Natalie C Tronson
When memories are retrieved they become labile, and subject to alteration by a process known as reconsolidation. Disruption of memory reconsolidation decreases the performance of learned responses, which is often attributed to erasure of the memory; in the case of Pavlovian learning, to a loss of the association between a conditioned stimulus (CS) and unconditioned stimulus (US). However, an alternative interpretation is that disrupting reconsolidation does not erase memories, but blunts their emotional/motivational impact...
May 3, 2018: Neuropsychopharmacology: Official Publication of the American College of Neuropsychopharmacology
https://www.readbyqxmd.com/read/29783994/large-scale-transcriptomic-analysis-reveals-that-pridopidine-reverses-aberrant-gene-expression-and-activates-neuroprotective-pathways-in-the-yac128-hd-mouse
#10
Rebecca Kusko, Jennifer Dreymann, Jermaine Ross, Yoonjeong Cha, Renan Escalante-Chong, Marta Garcia-Miralles, Liang Juin Tan, Michael E Burczynski, Ben Zeskind, Daphna Laifenfeld, Mahmoud Pouladi, Michal Geva, Iris Grossman, Michael R Hayden
BACKGROUND: Huntington Disease (HD) is an incurable autosomal dominant neurodegenerative disorder driven by an expansion repeat giving rise to the mutant huntingtin protein (mHtt), which is known to disrupt a multitude of transcriptional pathways. Pridopidine, a small molecule in development for treatment of HD, has been shown to improve motor symptoms in HD patients. In HD animal models, pridopidine exerts neuroprotective effects and improves behavioral and motor functions. Pridopidine binds primarily to the sigma-1 receptor, (IC50 ~ 100 nM), which mediates its neuroprotective properties, such as rescue of spine density and aberrant calcium signaling in HD neuronal cultures...
May 21, 2018: Molecular Neurodegeneration
https://www.readbyqxmd.com/read/29782435/biobehavioral-responses-of-preterm-infants-to-conventional-and-swaddled-tub-baths-a-randomized-crossover-trial
#11
Patrícia de Freitas, Mariana Bueno, Diane Holditch-Davis, Hudson Pires Santos, Amélia Fumiko Kimura
Bathing is a routine care procedure that exposes preterm infants to prolonged handling, which could cause stress and potentially disrupt infants' biobehavioral responses. The aim of this double-blind randomized crossover trial was to compare the preterm infant's body temperature, heart rate (HR), peripheral capillary oxygen saturation (SpO2), salivary cortisol levels, and sleep-wake states during and after swaddled and conventional tub baths. Forty-three infants born at 32 to 36 weeks postmenstrual age, weighing 2225 g or less, were enrolled in the study...
May 18, 2018: Journal of Perinatal & Neonatal Nursing
https://www.readbyqxmd.com/read/29781731/neuropsychologists-as-primary-care-providers-of-cognitive-health-a-novel-comprehensive-cognitive-wellness-service-delivery-model
#12
Patricia A Pimental, John B O'Hara, Jessica L Jandak
By virtue of their extensive knowledge base and specialized training in brain-behavior relationships, neuropsychologists are especially poised to execute a unique broad-based approach to overall cognitive wellness and should be viewed as primary care providers of cognitive health. This article will describe a novel comprehensive cognitive wellness service delivery model including cognitive health, anti-aging, lifelong wellness, and longevity-oriented practices. These practice areas include brain-based cognitive wellness, emotional and spiritually centric exploration, and related multimodality health interventions...
July 2018: Applied Neuropsychology. Adult
https://www.readbyqxmd.com/read/29781104/cavities-shield-birds-from-effects-of-artificial-light-at-night-on-sleep
#13
Thomas Raap, Rianne Pinxten, Marcel Eens
Light pollution is an ever increasing worldwide problem disrupting animal behavior. Artificial light at night (ALAN) has been shown to affect sleep in wild birds. Even cavity-nesting bird species may be affected when sleeping inside their cavity. Correlational studies suggest that light from outside the cavity/nest box, for example from street lights, may affect sleep. We used an experimental design to study to what extent nest boxes shield animals from effects of ALAN on sleep. We recorded individual sleep behavior of free-living great tits (Parus major) that were roosting in dark nest boxes and exposed their nest box entrance to ALAN the following night (1...
May 20, 2018: Journal of Experimental Zoology. Part A, Ecological and Integrative Physiology
https://www.readbyqxmd.com/read/29779582/animal-models-of-endocrine-disruption
#14
REVIEW
Heather B Patisaul, Suzanne E Fenton, David Aylor
Endocrine disrupting chemicals (EDCs) are compounds that alter the structure and function of the endocrine system and may be contributing to disorders of the reproductive, metabolic, neuroendocrine and other complex systems. Typically, these outcomes cannot be modeled in cell-based or other simple systems necessitating the use of animal testing. Appropriate animal model selection is required to effectively recapitulate the human experience, including relevant dosing and windows of exposure, and ensure translational utility and reproducibility...
June 2018: Best Practice & Research. Clinical Endocrinology & Metabolism
https://www.readbyqxmd.com/read/29779184/limbic-system-structure-volumes-and-associated-neurocognitive-functioning-in-former-nfl-players
#15
Christian Lepage, Marc Muehlmann, Yorghos Tripodis, Jakob Hufschmidt, Julie Stamm, Katie Green, Pawel Wrobel, Vivian Schultz, Isabelle Weir, Michael L Alosco, Christine M Baugh, Nathan G Fritts, Brett M Martin, Christine Chaisson, Michael J Coleman, Alexander P Lin, Ofer Pasternak, Nikos Makris, Robert A Stern, Martha E Shenton, Inga K Koerte
Chronic traumatic encephalopathy (CTE) is a neurodegenerative disease associated with exposure to repetitive head impacts. CTE has been linked to disruptions in cognition, mood, and behavior. Unfortunately, the diagnosis of CTE can only be made post-mortem. Neuropathological evidence suggests limbic structures may provide an opportunity to characterize CTE in the living. Using 3 T magnetic resonance imaging, we compared select limbic brain regional volumes - the amygdala, hippocampus, and cingulate gyrus - between symptomatic former National Football League (NFL) players (n = 86) and controls (n = 22)...
May 19, 2018: Brain Imaging and Behavior
https://www.readbyqxmd.com/read/29778877/an-insight-into-the-multi-scale-structures-and-pasting-behaviors-of-starch-following-citric-acid-treatment
#16
Yinqiang Huo, Binjia Zhang, Meng Niu, Caihua Jia, Siming Zhao, Qilin Huang, Hongying Du
Using combined analytical techniques, this work discloses how citric acid (CA) treatment affects the pasting features of starch from a view of multi-scale structural evolutions. The treatment induced disruption events in starch multi-level structures and thus modulated the pasting behaviors. A structure-property relationship was proposed to rationalize CA effects on starch pasting properties. Specifically, CA disrupted starch structures from molecular scale to micron scale, eventually reducing pasting temperature and paste viscosities...
May 17, 2018: International Journal of Biological Macromolecules
https://www.readbyqxmd.com/read/29777165/hiv-1-proteins-dysregulate-motivational-processes-and-dopamine-circuitry
#17
Sarah J Bertrand, Charles F Mactutus, Steven B Harrod, Landhing M Moran, Rosemarie M Booze
Motivational alterations, such as apathy, in HIV-1+ individuals are associated with decreased performance on tasks involving frontal-subcortical circuitry. We used the HIV-1 transgenic (Tg) rat to assess effect of long-term HIV-1 protein exposure on motivated behavior using sucrose (1-30%, w/v) and cocaine (0.01-1.0 mg/kg/infusion) maintained responding with fixed-ratio (FR) and progressive-ratio (PR) schedules of reinforcement. For sucrose-reinforced responding, HIV-1 Tg rats displayed no change in EC50 relative to controls, suggesting no change in sucrose reinforcement but had a downward shifted concentration-response curves, suggesting a decrease in response vigor...
May 18, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29777038/mechanical-stability-of-the-cell-nucleus-roles-played-by-the-cytoskeleton-in-nuclear-deformation-and-strain-recovery
#18
Xian Wang, Haijiao Liu, Min Zhu, Changhong Cao, Zhensong Xu, Yonit Tsatskis, Kimberly Lau, Chikin Kuok, Tobin Filleter, Helen McNeill, Craig A Simmons, Sevan Hopyan, Yu Sun
Extracellular forces transmitted through the cytoskeleton can deform the cell nucleus. Large nuclear deformation increases the risk of disrupting the nuclear envelope's integrity and causing DNA damage. Mechanical stability of the nucleus defines its capability of maintaining nuclear shape by minimizing nuclear deformation and recovering strain when deformed. Understanding the deformation and recovery behavior of the nucleus requires characterization of nuclear viscoelastic properties. Here, we quantified the decoupled viscoelastic parameters of the cell membrane, cytoskeleton, and the nucleus...
May 18, 2018: Journal of Cell Science
https://www.readbyqxmd.com/read/29776999/stumbling-corrective-reaction-elicited-by-mechanical-and-electrical-stimulation-of-the-saphenous-nerve-in-walking-mice
#19
William Paganini Mayer, Turgay Akay
The ability to walk around in a natural environment requires the capacity to cope with unexpected obstacles that may disrupt locomotion. One such mechanism is called the stumbling corrective reaction (SCR) that enables animals to step over obstacles that would otherwise disturb the progression of swing movement. Here we use in vivo motion analysis and physiological recording techniques to describe the SCR in mice. We show that SCR can be elicited consistently in mice during locomotion by inserting an obstacle along the path of leg movement during swing phase...
May 18, 2018: Journal of Experimental Biology
https://www.readbyqxmd.com/read/29776592/response-to-metals-treatment-of-fra1-a-member-of-the-ap-1-transcription-factor-family-in-p-lividus-sea-urchin-embryos
#20
Roberta Russo, Rosa Bonaventura, Marco Chiaramonte, Caterina Costa, Valeria Matranga, Francesca Zito
Lithium (Li), Nickel (Ni), and Zinc (Zn) are metals normally present in the seawater, although they can have adverse effects on the marine ecosystem at high concentrations by interfering with many biological processes. These metals are toxic for sea urchin embryos, affecting their morphology and developmental pathways. In particular, they perturb differently the correct organization of the embryonic axes (animal-vegetal, dorso-ventral): Li is a vegetalizing agent and Ni disrupts the dorso-ventral axis, while Zn has an animalizing effect...
May 5, 2018: Marine Environmental Research
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