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https://www.readbyqxmd.com/read/29904575/recent-advances-in-transfusions-in-neonates-infants
#1
REVIEW
Ruchika Goel, Cassandra D Josephson
Transfusions of red blood cells (RBCs), platelets, and plasma are critical therapies for infants and neonates (particularly preterm neonates) in the neonatal intensive care unit, who are the most frequently transfused subpopulation across all ages. Although traditionally a significant gap has existed between the blood utilization and the evidence base essential to adequately guide transfusion practices in infants and neonates, pediatric transfusion medicine is evolving from infancy and gradually coming of age...
2018: F1000Research
https://www.readbyqxmd.com/read/29903905/idiopathic-intracranial-hypertension-consensus-guidelines-on-management
#2
REVIEW
Susan P Mollan, Brendan Davies, Nick C Silver, Simon Shaw, Conor L Mallucci, Benjamin R Wakerley, Anita Krishnan, Swarupsinh V Chavda, Satheesh Ramalingam, Julie Edwards, Krystal Hemmings, Michelle Williamson, Michael A Burdon, Ghaniah Hassan-Smith, Kathleen Digre, Grant T Liu, Rigmor Højland Jensen, Alexandra J Sinclair
The aim was to capture interdisciplinary expertise from a large group of clinicians, reflecting practice from across the UK and further, to inform subsequent development of a national consensus guidance for optimal management of idiopathic intracranial hypertension (IIH). METHODS: Between September 2015 and October 2017, a specialist interest group including neurology, neurosurgery, neuroradiology, ophthalmology, nursing, primary care doctors and patient representatives met. An initial UK survey of attitudes and practice in IIH was sent to a wide group of physicians and surgeons who investigate and manage IIH regularly...
June 14, 2018: Journal of Neurology, Neurosurgery, and Psychiatry
https://www.readbyqxmd.com/read/29901487/a-core-set-of-outcome-measures-for-adults-with-neurologic-conditions-undergoing-rehabilitation-a-clinical-practice-guideline
#3
Jennifer L Moore, Kirsten Potter, Kathleen Blankshain, Sandra L Kaplan, Linda C OʼDwyer, Jane E Sullivan
BACKGROUND: Use of outcome measures (OMs) in adult neurologic physical therapy is essential for monitoring changes in a patient's status over time, quantifying observations and patient-reported function, enhancing communication, and increasing the efficiency of patient care. OMs also provide a mechanism to compare patient and organizational outcomes, examine intervention effectiveness, and generate new knowledge. This clinical practice guideline (CPG) examined the literature related to OMs of balance, gait, transfers, and patient-stated goals to identify a core set of OMs for use across adults with neurologic conditions and practice settings...
June 12, 2018: Journal of Neurologic Physical Therapy: JNPT
https://www.readbyqxmd.com/read/29895309/very-high-intact-protein-formula-successfully-provides-protein-intake-according-to-nutritional-recommendations-in-overweight-critically-ill-patients-a-double-blind-randomized-trial
#4
Arthur R H van Zanten, Laurent Petit, Jan De Waele, Hans Kieft, Janneke de Wilde, Peter van Horssen, Marianne Klebach, Zandrie Hofman
BACKGROUND: Optimal energy and protein provision through enteral nutrition is essential for critically ill patients. However, in clinical practice, the intake achieved is often far below the recommended targets. Because no polymeric formula with sufficient protein content is available, adequate protein intake can be achieved only by supplemental amino acids or semi-elemental formula administration. In the present study, we investigated whether protein intake can be increased with a new, very high intact-protein formula (VHPF) for enteral feeding...
June 12, 2018: Critical Care: the Official Journal of the Critical Care Forum
https://www.readbyqxmd.com/read/29895249/strategies-for-continued-successful-treatment-in-patients-with-alzheimer-s-disease-an-overview-of-switching-between-pharmacological-agents
#5
Rafael Blesa, Kazuhiro Toriyama, Kengo Ueda, Sean Knox, George Grossberg
INTRODUCTION: Alzheimer's disease (AD) is the most common cause of dementia, characterized by a progressive decline in cognition and function. Current treatment options for AD include the cholinesterase inhibitors (ChEIs) donepezil, galantamine, and rivastigmine, as well as the N-methyl-D-aspartate receptor antagonist memantine. Treatment guidelines recommend the use of ChEIs as standard of care first-line therapy. Several randomized clinical studies have demonstrated the benefits of ChEIs on cognition, global function, behavior and activities of daily living...
June 12, 2018: Current Alzheimer Research
https://www.readbyqxmd.com/read/29892322/thromboprophylaxis-in-head-and-neck-microvascular-reconstruction
#6
REVIEW
Manoj Abraham, Arvind Badhey, Shirley Hu, Sameep Kadakia, J K Rasamny, Augustine Moscatello, Yadranko Ducic
Head and neck patients undergoing microvascular reconstruction are at high risk for thromboembolism. While the prevention of thromboembolism has become an essential aspect of care, within the field of microsurgery, concern for anastomotic complications have hindered the creation of an accepted regimen. The aim of this review was to evaluate the risks and benefits of prophylactic agents for thromboprophylaxis. A literature search was conducted in MEDLINE, Cochrane Library, and PubMed/NCBI databases. Articles discussing thromboprophylaxis in otolaryngology, head and neck surgery, or microvascular reconstruction were considered in the review from the past 30 years...
June 2018: Craniomaxillofacial Trauma & Reconstruction
https://www.readbyqxmd.com/read/29891466/development-of-a-tailored-intervention-with-computerized-clinical-decision-support-to-improve-quality-of-care-for-patients-with-knee-osteoarthritis-multi-method-study
#7
Stijn Van de Velde, Tiina Kortteisto, David Spitaels, Gro Jamtvedt, Pavel Roshanov, Ilkka Kunnamo, Bert Aertgeerts, Per Olav Vandvik, Signe Flottorp
BACKGROUND: Clinical practice patterns greatly diverge from evidence-based recommendations to manage knee osteoarthritis conservatively before resorting to surgery. OBJECTIVE: This study aimed to tailor a guideline-based computerized decision support (CDS) intervention that facilitates the conservative management of knee osteoarthritis. METHODS: Experts with backgrounds in clinical medicine, research, implementation, or health informatics suggested the most important recommendations for implementation, how to develop an implementation strategy, and how to form the CDS algorithms...
June 11, 2018: JMIR Research Protocols
https://www.readbyqxmd.com/read/29890556/-management-of-clostridium-difficile-infections-at-german-intensive-care-units-results-from-a-survey-among-intensivists
#8
Jan Bruensing, Lukas Buendgens, Christoph Jochum, Ulf Herbers, Ali Canbay, Georg Braun, Christian Trautwein, Wolfgang Huber, Alexander Koch, Frank Tacke
BACKGROUND:  Clostridium difficile associated colitis is a frequent cause of nosocomial diarrhea at the intensive care unit (ICU) and is associated with poor prognosis in critically ill patients. Few studies have evaluated the efficacy of treatment options or adherence to guideline recommendations of Clostridium difficile infections at the ICU. METHODS:  Therefore, on behalf of the Gastroenterology Intensive Care Medicine working group of the DGVS, we have conducted an online-based survey among leading intensivists in Germany...
June 2018: Zeitschrift Für Gastroenterologie
https://www.readbyqxmd.com/read/29889132/less-or-more-hemodynamic-monitoring-in-critically-ill-patients
#9
Mathieu Jozwiak, Xavier Monnet, Jean-Louis Teboul
PURPOSE OF REVIEW: Hemodynamic investigations are required in patients with shock to identify the type of shock, to select the most appropriate treatments and to assess the patient's response to the selected therapy. We discuss how to select the most appropriate hemodynamic monitoring techniques in patients with shock as well as the future of hemodynamic monitoring. RECENT FINDINGS: Over the last decades, the hemodynamic monitoring techniques have evolved from intermittent toward continuous and real-time measurements and from invasive toward less-invasive approaches...
June 7, 2018: Current Opinion in Critical Care
https://www.readbyqxmd.com/read/29887235/laboratory-testing-in-primary-care-a-systematic-review-of-health-it-impacts
#10
REVIEW
Éric Maillet, Guy Paré, Leanne M Currie, Louis Raymond, Ana Ortiz de Guinea, Marie-Claude Trudel, Josianne Marsan
INTRODUCTION: Laboratory testing in primary care is a fundamental process that supports patient management and care. Any breakdown in the process may alter clinical information gathering and decision-making activities and can lead to medical errors and potential adverse outcomes for patients. Various information technologies are being used in primary care with the goal to support the process, maximize patient benefits and reduce medical errors. However, the overall impact of health information technologies on laboratory testing processes has not been evaluated...
August 2018: International Journal of Medical Informatics
https://www.readbyqxmd.com/read/29882866/a-systematic-review-on-healthcare-analytics-application-and-theoretical-perspective-of-data-mining
#11
REVIEW
Md Saiful Islam, Md Mahmudul Hasan, Xiaoyi Wang, Hayley D Germack, Md Noor-E-Alam
The growing healthcare industry is generating a large volume of useful data on patient demographics, treatment plans, payment, and insurance coverage—attracting the attention of clinicians and scientists alike. In recent years, a number of peer-reviewed articles have addressed different dimensions of data mining application in healthcare. However, the lack of a comprehensive and systematic narrative motivated us to construct a literature review on this topic. In this paper, we present a review of the literature on healthcare analytics using data mining and big data...
May 23, 2018: Healthcare (Basel, Switzerland)
https://www.readbyqxmd.com/read/29882581/icu-delirium-a-diagnostic-and-therapeutic-challenge-in-the-intensive-care-unit
#12
Katarzyna Kotfis, Annachiara Marra, Eugene Wesley Ely
Many patients treated in the intensive care unit (ICU) experience pain, that is a source of suffering and leaves a long-term imprint (chronic pain, post-traumatic stress disorder). Nearly 30% of patients experience pain at rest, the percentage increases to 50% during nursing procedures. Pain in ICU patients can be divided into four categories: continuous ICU treatment-related pain/discomfort, acute illness-related pain, intermittent procedural pain and pre-existing chronic pain present before ICU admission...
June 8, 2018: Anaesthesiology Intensive Therapy
https://www.readbyqxmd.com/read/29879456/critical-quality-evaluation-of-network-meta-analyses-in-dental-care
#13
REVIEW
Dae-Woo Lee, In-Soo Shin
OBJECTIVE: Network meta-analysis (NMA) is a new method to compare the effects of multiple treatments in dental care. We examined whether published NMA follow the key methodological reporting recommendations, the PRISMA Extension Statement. DESIGN: Collection of published systematic reviews with NMA in dental care DATA SOURCES: MEDLINE, EMBASE, and Web of Science searched from inception to May 1, 2017. STUDY SELECTION: All NMA published in dental journals comparing the clinical efficacy of three or more interventions with and without closed loops...
June 4, 2018: Journal of Dentistry
https://www.readbyqxmd.com/read/29878557/supplemental-parenteral-nutrition-review-of-the-literature-and-current-nutrition-guidelines
#14
Mary K Russell, Paul E Wischmeyer
Parenteral nutrition has significantly and positively affected the clinical care of patients for >50 years. The 2016 Society of Critical Care Medicine/American Society for Parenteral and Enteral Nutrition guidelines for the provision of nutrition support to adult patients emphasize the role of this therapy in attenuating the stress response and impacting the immune response, among other benefits. Malnutrition in hospitalized patients remains a major problem; it is underdiagnosed and often undertreated. Malnourished patients are more likely to suffer from infections, pneumonia, and pressure ulcers, among other serious concerns...
June 2018: Nutrition in Clinical Practice
https://www.readbyqxmd.com/read/29878554/controversies-in-the-use-of-lipid-injectable-emulsion-in-hospitalized-patients
#15
Jane Maria Gervasio
Soybean oil-based lipid injectable emulsion (SO-based ILE) is an 18-carbon, ω-6 macronutrient providing a concentrated source of calories, which can be administered in or with parenteral nutrition to patients unable to tolerate or consume adequate enteral nutrition. Beyond the provision of energy, SO-based ILE provides linoleic and linolenic acid, 2 essential fatty acids necessary for the prevention of essential fatty acid deficiency. However, SO-based ILE with its high levels of ω-6 fatty acids, long-chain triglycerides, phospholipid emulsifiers, and glycerin has been associated with worsening clinical outcomes, including increase of infections, lengthier intensive care and hospital stay, and prolonged mechanical ventilation...
June 2018: Nutrition in Clinical Practice
https://www.readbyqxmd.com/read/29876139/scrutinizing-screening-a-critical-interpretive-review-of-primary-care-provider-perspectives-on-mammography-decision-making-with-average-risk-women
#16
REVIEW
Sophia Siedlikowski, Carolyn Ells, Gillian Bartlett
Context: A decision to undertake screening for breast cancer often takes place within the primary care setting, but current controversies such as overdiagnosis and inconsistent screening recommendations based on evolving evidence render this a challenging process, particularly for average-risk women. Given the responsibility of primary care providers in counseling women in this decision-making process, it is important to understand their thoughts on these controversies and how they manage uncertainty in their practice...
2018: Public Health Reviews
https://www.readbyqxmd.com/read/29875112/acute-ischemic-stroke
#17
Bryan Boling, Katie Keinath
Acute ischemic stroke is a major cause of mortality and morbidity in the United States and worldwide. Despite the development of specialized stroke centers, mortality and morbidity as a result of acute ischemic strokes can and do happen anywhere. These strokes are emergency situations requiring immediate intervention. This article covers the fundamentals of care involved in treating patients with acute ischemic stroke, including essentials for the initial evaluation, basic neuroimaging, reperfusion therapies, critical care management, and palliative care, as well as current controversies...
2018: AACN Advanced Critical Care
https://www.readbyqxmd.com/read/29871622/impediments-to-communication-and-relationships-between-infertility-care-providers-and-patients
#18
Robert Klitzman
BACKGROUND: Infertility patients generally see provider-patient communication and relationships as important, but as often insufficient, raising critical questions regarding why these gaps persist, and how they might best be addressed. METHODS: Semi-structured interviews of approximately one hour each were conducted with 37 ART providers and patients (17 physicians, 10 other health providers, and 10 patients) and were thematically analyzed. RESULTS: Patients see clinicians' interactions as ranging widely from good to bad, related to several specific barriers and factors...
June 5, 2018: BMC Women's Health
https://www.readbyqxmd.com/read/29870136/guidelines-and-checklists-for-short-term-missions-in-global-pediatric-surgery-recommendations-from-the-american-academy-of-pediatrics-delivery-of-surgical-care-global-health-subcommittee-american-pediatric-surgical-association-global-pediatric-surgery-committee
#19
Marilyn Butler, Elizabeth Drum, Faye M Evans, Tamara Fitzgerald, Jason Fraser, Ai-Xuan Holterman, Howard Jen, Matthew Kynes, Jenny Kreiss, Craig D McClain, Mark Newton, Benedict Nwomeh, James O'Neill, Doruk Ozgediz, George Politis, Henry Rice, David Rothstein, Julie Sanchez, Mark Singleton, Francine S Yudkowitz
Pediatric surgeons, anesthesia providers, and nurses from North America and other high-income countries are increasingly engaged in resource-limited areas, with short-term missions as the most common form of involvement. However, consensus recommendations currently do not exist for short-term missions in pediatric general surgery and associated perioperative care. The American Academy of Pediatrics (AAP) Delivery of Surgical Care Subcommittee and American Pediatric Surgical Association (APSA) Global Pediatric Surgery Committee, with the American Pediatric Surgical Nurses Association, Inc...
May 2018: Paediatric Anaesthesia
https://www.readbyqxmd.com/read/29866144/standardised-data-reporting-from-pre-hospital-advanced-airway-management-a-nominal-group-technique-update-of-the-utstein-style-airway-template
#20
G A Sunde, A Kottmann, J K Heltne, M Sandberg, M Gellerfors, A Krüger, D Lockey, S J M Sollid
BACKGROUND: Pre-hospital advanced airway management with oxygenation and ventilation may be vital for managing critically ill or injured patients. To improve pre-hospital critical care and develop evidence-based guidelines, research on standardised high-quality data is important. We aimed to identify which airway data were most important to report today and to revise and update a previously reported Utstein-style airway management dataset. METHODS: We recruited sixteen international experts in pre-hospital airway management from Australia, United States of America, and Europe...
June 4, 2018: Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine
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