Shruti Chaturvedi, Ana G Antun, Andrew M Farland, Ryan Woods, Ara Metjian, Yara A Park, Gustaaf de Ridder, Briana Gibson, Raj S Kasthuri, Darla K Liles, Frank Akwaa, Todd Clover, Lisa Baumann Kreuziger, J Evan Sadler, Meera Sridharan, Ronald S Go, Keith R McCrae, Harsh Vardhan Upreti, Angela Liu, Ming Y Lim, Radhika Gangaraju, X Long Zheng, Jay S Raval, Camila Masias, Spero R Cataland, Andrew Johnson, Elizabeth Davis, Michael D Evans, Marshall A Mazepa
Immune-mediated thrombotic thrombocytopenic purpura (iTTP) is characterized by recurring episodes of thrombotic microangiopathy, causing ischemic organ impairment. Black patients are overrepresented in iTTP cohorts in the United States, but racial disparities in iTTP outcome and response to therapy have not been studied. Using the United States Thrombotic Microangiopathies Consortium iTTP Registry, we evaluated the impact of race on mortality and relapse-free survival (RFS) in confirmed iTTP in the United States from 1995 to 2020...
September 22, 2022: Blood