keyword
https://read.qxmd.com/read/38700750/infection-is-not-associated-with-plasma-or-cryoprecipitate-transfusion-volumes-in-trauma-a-retrospective-study-using-the-national-trauma-data-bank
#1
JOURNAL ARTICLE
Jacob C O'Dell, C Cameron McCoy, Robert D Winfield, Sue Min Lai, Edward F Ellerbeck, Christopher A Guidry
Background: Packed red blood cell (PRBC) transfusion has been shown to increase nosocomial infection risk in the injured population; however, the post-traumatic infectious risk profiles of non-PRBC blood products are less clear. We hypothesized that plasma (fresh frozen plasma [FFP]), platelet (PLT), and cryoprecipitate administration would not be associated with increased rates of nosocomial infections. Patients and Methods: We performed a retrospective, matched, case-control study utilizing the American College of Surgeons National Trauma Data Bank data for 2019...
May 3, 2024: Surgical Infections
https://read.qxmd.com/read/38658467/reconsidering-fresh-frozen-plasma-availability-to-reduce-blood-product-waste-during-massive-transfusion-events-in-trauma
#2
JOURNAL ARTICLE
Aricia Shen, Brent Di Meo, Ingrid A Perez, Yassar Hashim, Ara Ko, Daniel R Margulies, Ellen B Klapper, Galinos Barmparas
BACKGROUND: Within component therapy of massive transfusion protocol (MTP) in trauma, thawed plasma is particularly susceptible to expiring without use given its short 5-day shelf life. Optimizing the number of thawed products without compromising safety is important for hospital resource management. The goal is to examine thawed plasma utilization rates in trauma MTP events and optimize the MTP cooler content at our Level I trauma center. METHODS: Trauma MTP activations from 01/2019 to 12/2022 were retrospectively reviewed...
April 24, 2024: American Surgeon
https://read.qxmd.com/read/38634432/assessing-the-clinical-efficacy-of-low-volume-therapeutic-plasma-exchange-in-achieving-recovery-from-acute-liver-failure-induced-by-yellow-phosphorous-poisoning
#3
JOURNAL ARTICLE
Ancy Ninan, Ganesh Mohan, Vishal Shanbhag, Deepika Chenna, Shamee Shastry, Shwethapriya Rao
BACKGROUND: Acute liver failure (ALF) following yellow phosphorous (YP) ingestion is similar to acetaminophen-induced ALF and it has become a public concern in our region. This study assessed low volume therapeutic plasma exchange (LV-TPE) efficacy in improving the transplant free survival in YP poisoning. METHODS: Adult patients with toxicology reports of YP and ALF requiring critical care were included in the study. LV-TPE was planned for three consecutive days and three more if required...
June 2024: Journal of Clinical Apheresis
https://read.qxmd.com/read/38627682/continuation-of-chronic-antiplatelet-therapy-is-not-associated-with-increased-need-for-transfusions-a-cohort-study-in-critically-ill-septic-patients
#4
JOURNAL ARTICLE
Christian Fuchs, Christian S Scheer, Steffi Wauschkuhn, Marcus Vollmer, Konrad Meissner, Klaus Hahnenkamp, Matthias Gründling, Sixten Selleng, Thomas Thiele, Rainer Borgstedt, Sven-Olaf Kuhn, Sebastian Rehberg, Sean Selim Scholz
BACKGROUND: The decision to maintain or halt antiplatelet medication in septic patients admitted to intensive care units presents a clinical dilemma. This is due to the necessity to balance the benefits of preventing thromboembolic incidents and leveraging anti-inflammatory properties against the increased risk of bleeding. METHODS: This study involves a secondary analysis of data from a prospective cohort study focusing on patients diagnosed with severe sepsis or septic shock...
April 17, 2024: BMC Anesthesiology
https://read.qxmd.com/read/38610143/blood-transfusion-procedure-assessment-of-serbian-intensive-care-nurses-knowledge
#5
JOURNAL ARTICLE
Dragana Simin, Vladimir Dolinaj, Branislava Brestovački Svitlica, Jasmina Grujić, Dragana Živković, Dragana Milutinović
Many patients require administering one or more blood components during hospitalisation in the Intensive Care Unit (ICU). Therefore, nurses' knowledge of who is responsible for immediately administering blood transfusions, monitoring patients, and identifying and managing transfusion reactions is crucial. This cross-sectional descriptive-analytical study aimed to assess the knowledge of ICU nurses in tertiary healthcare institutions about blood transfusion procedures. The questionnaire about the transfusion procedure was designed and reviewed by experts...
March 25, 2024: Healthcare (Basel, Switzerland)
https://read.qxmd.com/read/38569856/-congenital-thrombotic-thrombocytopenic-purpura-diagnosed-in-adulthood-after-repeated-thrombocytopenia-since-neonatal-period
#6
JOURNAL ARTICLE
Teruhiko Yoshino, Takuro Kuriyama, Sae Utsumi, Takashi Shimakawa, Mariko Minami, Masayasu Hayashi, Yayoi Matsuo, Koichi Kokame, Eriko Nakamura, Masanori Matsumoto, Tetsuya Eto, Shuichi Taniguchi
A 27-year-old woman was diagnosed with idiopathic thrombocytopenic purpura in the neonatal period, and was admitted to our hospital after presenting with impaired consciousness, purpura, nausea and vomiting, with a platelet count of 10×109 /l. Congenital thrombotic thrombocytopenic purpura (cTTP) was suspected on the basis of recurrent thrombocytopenia and impaired consciousness, so tests for ADAMTS13 activity and inhibitor were performed. ADAMTS13 activity was severely decreased, ADAMTS13 inhibitor was negative, and platelet count increased after transfusion of fresh frozen plasma...
2024: [Rinshō Ketsueki] the Japanese Journal of Clinical Hematology
https://read.qxmd.com/read/38566573/consideration-for-alpha-gal-syndrome-in-two-critically-ill-persons-with-group-o-blood-who-received-group-b-plasma
#7
Maureen J Miller, Patricia Lee, Brian G Lee, Willy A Flegel, Kamille West-Mitchell, Kathleen Conry-Cantilena, Valeria De Giorgi
BACKGROUND: The U.S. Centers for Disease Control and Prevention (CDC) has reported increasing rates of alpha-gal syndrome, an allergic response after meat ingestion (AGS). AGS has been associated with prior exposure to tick bites or other biologics characterized by a life-threatening immunoglobulin E (IgE)-mediated hypersensitivity to galactose-alpha-1,3-galactose (alpha-gal) an oligosaccharide structurally similar to the group B antigen on red blood cells (RBC) found in most non-primate mammalian meat and products derived from these mammals...
April 3, 2024: Transfusion
https://read.qxmd.com/read/38560549/correlation-and-regression-analysis-applied-for-types-and-number-of-blood-transfusions-versus-transfusions-induced-adr-among-pediatric-haemato-oncology-and-thalassemia-patients
#8
JOURNAL ARTICLE
Manjula Gudhoor, Jessin Jhon, Navaneet Nair, Marion Anna, Abhilasha Sampagar, Madiwalayya Shivakantayya Ganachari
Introduction: Blood transfusion is a remedial intercession and a fundamental fragment of Current medical services framework. As indicated by the WHO the bonding is an action of moving blood or blood-items taken from a giver into the vasculature and in this manner the flowing blood of the recipient, done by embeddings an IV Needle/Catheter in the patient and followed by use of blood or the blood-items. In any case, the dangers of non-irresistible difficulties have gotten more obvious. These nonirresistible complexities called as adverse transfusion reactions (ATRs) can either be intense in nature or follow a postponed course...
December 2023: Hospital Pharmacy
https://read.qxmd.com/read/38525389/a-comparison-of-the-clinical-outcomes-of-minimum-and-maximum-hematocrit-levels-during-cardiopulmonary-bypass-cpb-in-low-risk-patients-undergoing-coronary-artery-bypass-graft-surgery-cabg-a-cross-sectional-study
#9
JOURNAL ARTICLE
Fatemeh Shiravi, Mehran Shahzamani, Sayyed Alireza Hosseini, Davood Shafie
BACKGROUND: This study investigated the clinical outcomes at the minimum and maximum levels of hematocrit (HCT) during cardiopulmonary bypass (CPB) in low-risk patients undergoing coronary artery bypass graft (CABG) surgery. MATERIALS AND METHODS: In this cross-sectional study, 85 patients who underwent CABG with an ejection fraction of greater than 35% were selected. Based on the HCT range during CPB, patients were divided into two groups: minimum HCT: HCT = 16-18% and maximum HCT: HCT = 25-27%...
2024: Advanced Biomedical Research
https://read.qxmd.com/read/38510368/anticoagulation-management-in-elderly-patients-with-proximal-femur-fractures%C3%A2-overview-of-current-concepts
#10
REVIEW
Yasmin Youssef, Anna K I M Dietrich, Annika Hättich
OBJECTIVES: Proximal femur fractures (PFF) are common injuries in elderly patients and can have considerable effects on their quality of life, morbidity, and mortality. Due to pre-existing comorbidities, the prevalence of anticoagulated patients is increasing. The right timing for surgery and perioperative anticoagulation treatment remains controversial. CONTENT: This overview aims to summarize current practices in the pre- and postoperative anticoagulation management and the recommended time to surgery in elderly patients with PFF...
December 2023: Innovative Surgical Sciences
https://read.qxmd.com/read/38505594/anesthetic-managements-morbidities-and-mortalities-in-retroperitoneal-sarcoma-patients-experiencing-perioperative-massive-blood-transfusion
#11
JOURNAL ARTICLE
Jun Wang, Jun Chen, Kunpeng Liu, Hua Zhang, Yue Wei, Libin Suo, Shuang Lan, Yanzhen Wang, Chenghua Luo, Lan Yao
OBJECTIVE: Given high risks of major bleeding during retroperitoneal sarcoma(RPS) surgeries, severe complications and deaths are common to see perioperatively. Thus, effective anesthetic management is the key point to ensuring the safety of patients. This study aimed to introduce anesthesia management and mortalities in RPS patients receiving massive blood transfusions during surgeries. METHODS: Records of RPS surgeries under general anesthesia from January 2016 through December 2021 were retrospectively retrieved from our database...
2024: Frontiers in Oncology
https://read.qxmd.com/read/38505580/management-of-severe-factor-xi-deficiency-in-pregnancy-a-case-report
#12
Fatima El Hassouni, Asmae Bentaleb, Sofia Lahbabi, Rajae Tachinante, Mohamed Elkhorassani, Mounia Yousfi
Factor XI (FXI) deficiency is one of the rarest coagulation disorders with a frequency of 1:1,000,000. A 30-year-old woman, diagnosed with FXI deficiency at the age of 4, was admitted to our maternity service at 25 weeks of gestation. The patient had no history of hemorrhage or abnormal bleeding, and the clinical examination was unremarkable. Antenatal care was also normal. The parturient was admitted in early labor at 38 weeks of gestation. Despite the absence of clinical hemorrhagic syndrome, a transfusion of fresh frozen plasma combined with tranexamic acid was initiated once the active stage of labor was started...
2024: SAGE Open Medical Case Reports
https://read.qxmd.com/read/38504263/effectiveness-and-safety-of-tourniquet-utilization-for-civilian-vascular-extremity-trauma-in-the-pre-hospital-settings-a-systematic-review-and-meta-analysis
#13
REVIEW
Ying-Chih Ko, Tou-Yuan Tsai, Chien-Kai Wu, Kai-Wei Lin, Ming-Ju Hsieh, Tzu-Pin Lu, Tasuku Matsuyama, Wen-Chu Chiang, Matthew Huei-Ming Ma
BACKGROUND: Tourniquets (TQ) have been increasingly adopted in pre-hospital settings recently. This study examined the effectiveness and safety of applying TQ in the pre-hospital settings for civilian patients with traumatic vascular injuries to the extremities. MATERIALS AND METHODS: We systematically searched the Ovid Embase, PubMed, and Cochrane Central Register of Controlled Trials databases from their inception to June 2023. We compared pre-hospital TQ (PH-TQ) use to no PH-TQ, defined as a TQ applied after hospital arrival or no TQ use at all, for civilian vascular extremity trauma patients...
March 19, 2024: World Journal of Emergency Surgery: WJES
https://read.qxmd.com/read/38497936/prevalence-and-outcomes-of-high-versus-low-ratio-plasma-to-red-blood-cell-resuscitation-in-a-multi-institutional-cohort-of-severely-injured-children
#14
JOURNAL ARTICLE
Steven C Mehl, Adam M Vogel, Amy E Glasgow, Suzanne Moody, Meera Kotagal, Regan F Williams, Mark L Kayton, Emily C Alberto, Randall S Burd, Thomas J Schroeppel, Joanne E Baerg, Amanda Munoz, William B Rothstein, Laura A Boomer, Eric M Campion, Caitlin Robinson, Rachel M Nygaard, Chad J Richardson, Denise I Garcia, Christian J Streck, Michaela Gaffley, John K Petty, Cynthia Greenwell, Samir Pandya, Alicia M Waters, Robert T Russell, Brian K Yorkgitis, Jennifer Mull, Jeffrey Pence, Matthew T Santore, Taleen A MacArthur, Denise B Klinkner, Shawn D Safford, Tanya Trevilian, Megan Cunningham, Christa Black, Jessica Rea, Ryan G Spurrier, Aaron R Jensen, Bethany J Farr, David P Mooney, Bavana Ketha, Melvin S Dassinger, Anna Goldenberg-Sandau, Janika San Roman, Todd M Jenkins, Richard A Falcone, Stephanie F Polites
BACKGROUND: The benefit of targeting high ratio fresh frozen plasma (FFP):red blood cell (RBC) transfusion in pediatric trauma resuscitation is unclear as existing studies are limited to patients who retrospectively met criteria for massive transfusion. The purpose of this study is to evaluate the use of high ratio FFP:RBC transfusion and the association with outcomes in children presenting in shock. METHODS: A post-hoc analysis of a 24-institution prospective observational study (4/2018-9/2019) of injured children <18 years with elevated age-adjusted shock index was performed...
March 18, 2024: Journal of Trauma and Acute Care Surgery
https://read.qxmd.com/read/38494437/periprocedural-risk-predictors-affecting-long-term-prognosis-in-patients-with-chronic-obstructive-pulmonary-disease-undergoing-coronary-artery-bypass-grafting
#15
JOURNAL ARTICLE
Aleksander Dokollari, Serge Sicouri, Leila Hosseinian, Ozgun Erten, Basel Ramlawi, Gianluigi Bisleri, Massimo Bonacchi, Noah Sicouri, Gianluca Torregrossa, Francis P Sutter
OBJECTIVE: This study sought to identify periprocedural risk predictors that affect long-term prognosis in patients with chronic obstructive pulmonary disease (COPD) undergoing isolated coronary artery bypass grafting (CABG). METHODS: All consecutive 4,871 patients undergoing isolated CABG between May 2005 and June 2021 were included. Patients with and without COPD were compared for baseline demographics and preoperative characteristics. A propensity-matched analysis was used to compare the 2 groups...
January 1, 2024: Texas Heart Institute Journal
https://read.qxmd.com/read/38467589/association-of-perioperative-transfusion-of-fresh-frozen-plasma-and-outcomes-after-cardiac-surgery
#16
JOURNAL ARTICLE
Jake V Hinton, Zhongyue Xing, Calvin Fletcher, Luke A Perry, Alexandra Karamesinis, Jenny Shi, Jahan C Penny-Dimri, Dhruvesh Ramson, Tim G Coulson, Reny Segal, Julian A Smith, Jenni Williams-Spence, Laurence Weinberg, Rinaldo Bellomo
BACKGROUND: Fresh frozen plasma (FFP) transfusion is used to manage coagulopathy and bleeding in cardiac surgery patients despite uncertainty about its safety and effectiveness. METHODS: We performed a propensity score matched analysis of the Australian and New Zealand Society of Cardiac and Thoracic Surgeons National Cardiac Surgery Database including patients from 39 centres from 2005 to 2018. We investigated the association of perioperative FFP transfusion with mortality and other clinical outcomes...
March 11, 2024: Acta Anaesthesiologica Scandinavica
https://read.qxmd.com/read/38467466/efficacy-of-intraoperative-blood-salvage-and-autotransfusion-in-living-donor-liver-transplantation-a-retrospective-propensity-matched-case-control-study
#17
JOURNAL ARTICLE
Jongchan Lee, Sujung Park, Jae Geun Lee, Sungji Choo, Bon-Nyeo Koo
BACKGROUND: Liver transplantation (LT) may be associated with massive blood loss and the need for allogeneic blood transfusion. Intraoperative blood salvage autotransfusion (IBSA) can reduce the need for allogeneic blood transfusion. This study aimed to investigate the effectiveness of blood salvage in LT. METHODS: Among 355 adult patients who underwent elective living-donor LT between January 1, 2019, and December 31, 2022, 59 recipients without advanced hepatocellular carcinoma received IBSA using Cell Saver (CS group)...
March 12, 2024: Korean Journal of Anesthesiology
https://read.qxmd.com/read/38433869/protocol-to-evaluate-the-efficacy-and-safety-of-tolvaptan-in-patients-with-refractory-ascites-after-liver-resection-an-open-label-single-arm-phase-i-ii-study
#18
JOURNAL ARTICLE
Yosuke Namba, Tsuyoshi Kobayashi, Shintaro Kuroda, Masakazu Hashimoto, Daisuke Takei, Sotaro Fukuhara, Ko Oshita, Keiso Matsubara, Naruhiko Honmyo, Ryosuke Nakano, Hiroshi Sakai, Hiroyuki Tahara, Masahiro Ohira, Kentaro Ide, Hideki Ohdan
BACKGROUND: In patients with chronic liver diseases such as cirrhosis, massive ascites after hepatic resection is the cause of prolonged hospitalization and worsening prognosis. Recently, the efficacy of tolvaptan in refractory ascites has been reported; however, there are no reports on the efficacy or safety of tolvaptan for refractory ascites after hepatic resection. This study aims to evaluate the efficacy of early administration of tolvaptan in patients with refractory ascites after hepatic resection...
March 2024: International journal of surgery protocols
https://read.qxmd.com/read/38429064/measuring-evidence-based-clinical-guideline-compliance-in-the-paediatric-intensive-care-unit
#19
JOURNAL ARTICLE
Rebecca E Hay, Dori-Ann Martin, Gary J Rutas, Shelina M Jamal, Simon J Parsons
BACKGROUND: Evidence-based clinical care guidelines improve medical treatment by reducing error, improving outcomes and possibly lowering healthcare costs. While some data exist on individual guideline compliance, no data exist on overall compliance to multiple nuanced guidelines in a paediatric intensive care setting. METHODS: Guideline compliance was observed and measured with a prospective cohort at a tertiary academic paediatric medical-surgical intensive care unit...
March 1, 2024: BMJ Open Quality
https://read.qxmd.com/read/38428676/role-of-vv-ecmo-tracheal-surgery-and-carinal-resection-two-case-reports
#20
Á Mingote, D Simic Silva, F J Gómez Nieto, A I González Román, J García Fernández
The aim of this study is to describe the anaesthesia management of two patients undergoing carinal resection under veno-venous extracorporeal membrane oxygenation (VV ECMO). In both cases, anaesthesia was induced and then maintained with inhalational agents during pneumonectomy and mediastinoscopy (respectively). Then the jugular and femoral veins were cannulated and VV ECMO was started after heparinization. One of the patients presented bleeding during surgery, which was treated with low-dose vasopressors (norepinephrine) and transfusion of platelets, fresh frozen plasma, and concentrated red blood cells...
February 28, 2024: Revista española de anestesiología y reanimación
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