keyword
https://read.qxmd.com/read/38497344/trigger-factors-in-patients-with-a-patent-foramen-ovale-associated-stroke-a-case-crossover-study
#1
JOURNAL ARTICLE
Maikel Immens, Merel Sanne Ekker, Esmee Verburgt, Jamie Verhoeven, Mijntje Schellekens, Nina Hilkens, Esther Boot, Mayte van Alebeek, Paul J A M Brouwers, Renate Arntz, Gert van Dijk, Rob Gons, Inge van Uden, Tom den Heijer, Paul L M de Kort, K de Laat, Anouk Gw van Norden, Sarah E Vermeer, Marian van Zagten, Robert J van Oostenbrugge, Marieke Wermer, Paul J Nederkoorn, Henk Kerkhoff, F Rooyer, Frank van Rooij, Ido van den Wijngaard, Catharina Klijn, Anil M Tuladhar, Tim Ten Cate, Frank-Erik de Leeuw
BACKGROUND: Patent foramen ovale (PFO) is a congenital anatomical variant which is associated with strokes in young adults. Contrary to vascular risk factors and atherosclerosis, a PFO is present from birth. However, it is completely unknown how an anatomical structure that is already present at birth in a large proportion of the population, can convert into a PFO that causes stroke in a few. Recent studies reported a significant association between certain trigger factors and ischemic stroke in young adults...
March 18, 2024: International Journal of Stroke: Official Journal of the International Stroke Society
https://read.qxmd.com/read/38495079/heart-brain-clinic-an-integrated-approach-to-stroke-care
#2
JOURNAL ARTICLE
Muhammad Bilal Tariq, Syed Kalimullah S Qadri, Anjail Sharrief, Kathleen Tulod, Abhijeet Dhoble, Sidhanta Gurung, Maria Jamilla Lacap, Munachi Okpala, Bharti Manwani, Richard W Smalling, Nicole Gonzales
BACKGROUND AND OBJECTIVES: Multidisciplinary clinics have been shown to improve care. Patients with patent foramen ovale (PFO)-associated stroke need evaluation by cardiology and neurology specialists. We report our experience creating a multidisciplinary Structural Heart Brain Clinic (HBC) with a focus on patients with PFO-associated stroke. METHODS: Demographic and clinical data were retrospectively collected for patients with PFO-associated ischemic stroke. Patients with PFO-associated stroke were divided into a standard care group and Heart Brain Clinic group for analysis...
December 2023: Neurology. Clinical Practice
https://read.qxmd.com/read/38493455/atrial-septum-anatomy-as-a-predictor-of-ischemic-neurological-episodes-in-patients-with-patent-foramen-ovale
#3
JOURNAL ARTICLE
Przemysław Węglarz, Michał Węgiel, Piotr Kuszewski, Ewa Konarska-Kuszewska, Michał Staszel, Michał Nowok, Grzegorz Bajor, Katarzyna Mizia-Stec, Artur Dziewierz, Tomasz Rakowski
No abstract text is available yet for this article.
March 17, 2024: Kardiologia Polska
https://read.qxmd.com/read/38485682/percutaneous-patent-foramen-ovale-closure-stroke-and-beyond
#4
JOURNAL ARTICLE
Sandeep Randhawa, Jawahar L Mehta, Gaurav Dhar
Over 750,000 individuals suffer from stroke annually in the United States, with 87% of these strokes being ischemic in nature. Roughly 40% of ischemic strokes occur in individuals 60 years of age or under. A quarter of all ischemic strokes have no identifiable cause despite extensive workup and are deemed cryptogenic in nature. Patent Foramen Ovales (PFO) has been postulated in stroke causation by either paradoxical embolization or platelet activation in the tunnel of the defect. The incidence of PFO is reported to be 15-25% in the general population but rises to 40% in patients with cryptogenic stroke...
March 11, 2024: Current Cardiology Reviews
https://read.qxmd.com/read/38470517/decompression-sickness-of-the-inner-ear-and-relationship-with-a-patent-oval-foramen-a-study-of-61-cases
#5
JOURNAL ARTICLE
Raphaële Quatre, Bertrand Delafosse, Sébastien Schmerber, Edouard Soriano
OBJECTIVE: To discuss the link between inner ear decompression sickness and patent foramen ovale. MATERIALS AND METHODS: Monocentric and retrospective study on decompression sickness of the inner ear requiring hyperbaric chamber treatment, from 2014 to 2021. RESULTS: Sixty-one patients of inner ear decompression sickness were included in this study. Twenty-four patients had vestibular injuries, 28 cochlear injuries and 9 cochleo-vestibular injuries...
March 12, 2024: European Archives of Oto-rhino-laryngology
https://read.qxmd.com/read/38464802/quadri-chamber-thrombi-and-impending%C3%A2-paradoxical-embolism-thrombus-in-transit-through-patent-foramen-ovale
#6
Samier Deen, Paul Gilbert, Kush Agrawal, Abby Borhan
Thrombus-in-transit through patent foramen ovale (PFO) is an extremely rare diagnosis that can often be associated with pulmonary embolism. Currently, data exists to guide management options; however, there is no medical consensus with regard to the optimal treatment strategy for thrombus-in-transit through PFO.
March 6, 2024: JACC. Case reports
https://read.qxmd.com/read/38464577/transhepatic-approach-of-patent-foramen-ovale-closure-in-the-setting-of-congenital-inferior-vena-cava-anomaly
#7
Deepa Soodi, Somto Nwaedozie, Milind Shah, Sudhakar Girotra
Patent foramen ovale (PFO) is the most common interatrial septal abnormality. The indications for PFO device closure are still being evaluated, with the most common reason being to prevent cerebrovascular accidents (CVA) caused by paradoxical embolism of deep vein thrombosis (DVT) in the lower extremities. This procedure is usually performed through percutaneous intervention using femoral vein access. Here, we present a case of PFO closure using a transhepatic approach, as femoral vein access was not feasible due to an interrupted inferior vena cava (IVC)...
March 2024: Clinical Case Reports
https://read.qxmd.com/read/38462432/safety-monitoring-of-bivalent-mrna-covid-19-vaccine-among-pregnant-persons-in-the-vaccine-adverse-event-reporting-system-united-states-september-1-2022-march-31-2023
#8
JOURNAL ARTICLE
Pedro L Moro, Grace Carlock, Nimita Fifadara, Tei Habenicht, Bicheng Zhang, Penelope Strid, Paige Marquez
BACKGROUND: Pregnant persons are at increased risk of severe COVID-19 illness. Bivalent mRNA COVID-19 vaccination is recommended for everyone, including pregnant persons. However, data are limited on the safety of bivalent mRNA COVID-19 vaccination during pregnancy. OBJECTIVE: To evaluate and summarize reports to the Vaccine Adverse Event Reporting System (VAERS), a national spontaneous reporting system, among pregnant persons who received bivalent mRNA COVID-19 vaccine...
March 9, 2024: Vaccine
https://read.qxmd.com/read/38459828/paradoxical-embolic-stroke-following-percutaneous-transluminal-angioplasty-in-a-hemodialysis-patient
#9
Xun Luo, Jie Yu, Hailang Xiao, Lang Dai, Yang Jiang, Xiaohui Xia, Wenjian Shi, Fan Zhang
Paradoxical embolism is a medical condition characterized by the migration of an embolus from a venous source into the systemic circulation. This occurs through a specific cardiac abnormality known as a right-to-left shunt, ultimately resulting in the possibility of arterial embolism. Patent foramen ovale (PFO) is the most common cause of intracardiac shunting. We reported a rare case of a 56-year-old man on hemodialysis with PFO and arteriovenous fistula dysfunction who suffered a paradoxical embolic ischemic stroke after percutaneous transluminal angioplasty...
March 9, 2024: Seminars in Dialysis
https://read.qxmd.com/read/38455830/a-patent-foramen-ovale-with-an-atrial-septal-aneurysm-in-a-patient-presenting-with-deep-vein-thrombosis-and-pulmonary-embolism
#10
Gabriel Panama, Adolfo Martinez, Saif Alattal, Preeti Banga, Sandeep Banga, Mohammed Quintar
Patent foramen ovale (PFO) is an embryogenic remnant that can be found in healthy adults with no repercussions. However, it poses a risk of paradoxical embolism. In patients with known embolic stroke, the risk of recurrence is greater. A PFO can be accompanied by morphological variants such as atrial septal aneurysms (ASA). These have been shown to further increase the risk of stroke and embolism. This is a case of a patient who presented to the emergency department with deep vein thrombosis and sub-massive pulmonary embolism...
February 2024: Curēus
https://read.qxmd.com/read/38449963/a-systematic-review-of-the-management-of-knee-osteoarthritis-by-proximal-fibular-osteotomy-in-the-indian-population
#11
REVIEW
Aditya Pundkar, Sandeep Shrivastav, Rohan Chandanwale, Ankit M Jaiswal, Saksham Goyal
This systematic review aims to assess the management of knee osteoarthritis through proximal fibular osteotomy (PFO) in the Indian population by synthesizing data from various prospective cohort and interventional studies. We seek to provide an overview of the effectiveness and safety of PFO as a treatment modality and offer insights into its potential implications for clinical practice in India. A systematic search strategy was employed, targeting multiple medical databases to identify relevant studies published from 2018 to 2023...
February 2024: Curēus
https://read.qxmd.com/read/38445759/patent-foramen-ovale-closure-versus-drug-therapy-in-patients-over-60-years-and-a-follow-up-of-5-years
#12
JOURNAL ARTICLE
Angelika Eichelmann, Ralf Kubini, Dejan Nachoski, Christoph Kosinski, Michael Becker, Ali Aljalloud
BACKGROUND: The advantages of patent foramen ovale (PFO) closure as protection from a recurrence of stroke remains controversial compared to drug therapy, especially in patients over 60 years. HYPOTHESIS: The aim of the study is to compare recurrence of stroke in patients over 60 years old with PFO closure versus drug therapy alone. METHODS: We included 342 patients over 60 years who suffered a crytopgenic stroke, and were also accepted for a PFO closure...
February 2024: Clinical Cardiology
https://read.qxmd.com/read/38440550/syndromic-piere-robbin-sequence-a-rare-presentation-in-association-with-multiple-heart-defects-and-type-iii-stickler-syndrome
#13
JOURNAL ARTICLE
Soubia Akhtar, Muhammad Wasif, Yumna Afzal, Iqra Shahab, Rahim Dhanani, Abdul Rauf Shaikh
Pierre Robin Sequence (PRS), a rare congenital disorder, is a triad of micrognathia, glossoptosis, and tongue based airway obstruction (TBSO). It may occur as isolated anomaly (iPRS) or as a part of a syndrome (sPRS), like that seen in association with Stickler Syndrome. Approximately 20% of children with PRS have congenital heart diseases. To the best of our knowledge this case of a one-day old infant is the first one to be reported as having two heart defects; patent ductus arteriosus and patent foramen ovale in Pierre Robbin Sequence child...
February 2024: Indian Journal of Otolaryngology and Head and Neck Surgery
https://read.qxmd.com/read/38440117/pfo-spectrum-disorder-two-different-cerebrovascular-diseases-in-patients-with-pfo-as-detected-by-ai-brain-imaging-software
#14
JOURNAL ARTICLE
Raluca Ștefania Badea, Sorina Mihăilă-Bâldea, Athena Ribigan, Anca Negrilă, Nicolae Grecu, Andreea Nicoleta Marinescu, Florina Antochi, Cristina Tiu, Dragos Vinereanu, Bogdan Ovidiu Popescu
BACKGROUND: Patent foramen ovale (PFO) is a prevalent cardiac remnant of fetal anatomy that may pose a risk factor for stroke in some patients, while others can present with asymptomatic white matter (WM) lesions. The current study aimed to test the hypothesis that patients with a PFO who have a history of stroke or transient ischemic attack, compared to those without such a history, have a different burden and distribution of cerebral WM hyperintensities. Additionally, we tested the association between PFO morphological characteristics and severity of shunt, and their impact on the occurrence of ischemic cerebral vascular events and on the burden of cerebral WM lesions...
2024: Frontiers in Neurology
https://read.qxmd.com/read/38440035/increased-risk-of-cryptogenic-stroke-associated-with-patent-foramen-ovale-in-young-adults
#15
Alec J Knupp, Douglas A Smith
Ischemic stroke is defined as a reduction in blood flow to brain tissue that results in the deterioration and death of neurons in a matter of minutes. While often seen in older patients with a history of atherosclerosis of the major arteries, a subset of ischemic strokes occur in younger individuals with minimal to no prior risk factors. Further evaluation of these unknown, or cryptogenic, strokes has yielded positive findings of a patent foramen ovale (PFO) in a concerning number of cases. Cryptogenic strokes attributable to PFO present an important clinical occurrence because they do not fit the typical template regarding those most at risk for such acutely devastating outcomes, making their identification uniquely important for both immediate and long-term patient care...
February 2024: Curēus
https://read.qxmd.com/read/38428550/comparison-of-atrial-septal-defect-and-patent-foramen-ovale-in-cryptogenic-strokes
#16
JOURNAL ARTICLE
Constant Delabays, Pamela Correia, Eric Eeckhout, Alain Delabays, Patrik Michel
OBJECTIVES: Paradoxical embolism from right-to-left shunt through atrial septal defect (ASD) and patent foramen ovale (PFO) is a well-accepted cause of "cryptogenic" strokes (CS). To better understand the pathogenic role of ASD, we compared ASD patients with CS having a high and low likelihood of being PFO-related. METHODS: In the Acute Stroke Registry and Analysis of Lausanne, we calculated prevalence of PFO and ASD in CS patients undergoing echocardiography, and calculated odds ratios (OR) when compared to non-CS...
February 28, 2024: Journal of Stroke and Cerebrovascular Diseases: the Official Journal of National Stroke Association
https://read.qxmd.com/read/38416197/headache-patterns-in-patent-foramen-ovale-patients-beyond-migraine-with-aura
#17
JOURNAL ARTICLE
Raluca Ștefania Badea, N Grecu, A C Ribigan, F Antochi, C Tiu, B O Popescu
Patent foramen ovale (PFO) is a common cardiac anomaly linked with cryptogenic strokes and migraine, particularly migraine with aura. This study aims to explore the spectrum of headache disorders in PFO patients, focusing on identifying patterns beyond the well-established migraine-PFO connection. A retrospective observational study was conducted on patients diagnosed with PFO. Headache types were classified using the International Classification of Headache Disorders, 3rd edition. The study analyzed headache prevalence and patterns in PFO patients, comparing those with and without a history of stroke...
February 28, 2024: Journal of Neural Transmission
https://read.qxmd.com/read/38415485/assessment-of-the-characteristics-of-patent-foramen-ovale-associated-with-cryptogenic-stroke
#18
JOURNAL ARTICLE
Hong Pu, Qing Zhang, Jing Wu, Yuan Zhang, Yaxi Zhao, Ling Li
OBJECTIVE: This study aims to comprehensively assess the characteristics of patent foramen ovale (PFO) in relation to Cryptogenic Strok (CS) by utilizing transesophageal echocardiography (TEE) and contrast transthoracic echocardiography (c-TTE) and to identify high-risk factors associated with PFO-related CS. BACKGROUND: Transcatheter PFO closure has demonstrated its effectiveness in preventing PFO-related CS. Therefore, understanding the specific structural attributes of PFO associated with CS is imperative...
February 26, 2024: Current medical imaging
https://read.qxmd.com/read/38412438/amplatzer-or-figulla-flex-ii-occluder-a-comparative-study-of-outcomes-after-transcatheter-patent-foramen-ovale-closure
#19
JOURNAL ARTICLE
Stefan Toggweiler, Federico Moccetti, Nina Conrad, Lucca Loretz, Mehdi Madanchi, Matthias Bossard, Adrian Attiger-Toller, Florim Cuculi, Mathias Wolfrum
OBJECTIVES: Percutaneous closure of a patent foramen ovale (PFO) for the prevention of recurrent paradoxical thromboembolic events has been shown to be safe and effective in randomized controlled trials. However, it remains uncertain if differences in the structure and design of the occluder devices impact the outcomes. The aim of this study was to compare results of percutaneous PFO closure using 2 widely used double-disc occluders. METHODS: Consecutive patients who underwent percutaneous PFO closure with the Abbott Amplatzer occluder (APO) or the Occlutech Figulla-Flex-II occluder (OPO) at the Heart Center Lucerne between February 2017 and December 2022 were included in a registry...
February 23, 2024: Journal of Invasive Cardiology
https://read.qxmd.com/read/38412436/various-techniques-for-transcatheter-retrieval-of-the-atrial-septal-defect-or-patent-foramen-ovale-closure-devices-a-systematic-review
#20
JOURNAL ARTICLE
Alireza Khosravi, Seyedeh Mahnaz Mirbod, Maryam Boshtam, Farzad Shahsanaei, Erfan Zaker, Marzieh Tajmirriahi, Arsalan Khaledifar, Seyedeh Mojgan Mirbod, Mohammad Reza Movahed
Atrial septal abnormalities are common congenital lesions that remain asymptomatic in many patients until adulthood. Adults with atrial septal defects (ASD) most commonly have ostium secundum ASD. Transcatheter closure has become increasingly popular in recent years as a successful alternative method to surgery for treating ASD and patent foramen ovale (PFO). The overall rate of ASD transcatheter closure device embolization has been reported to be less than 1%; however, retrieving the device via surgery or by trans-catheter route can be necessary...
February 23, 2024: Journal of Invasive Cardiology
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