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Karen Vitting Andersen
No abstract text is available yet for this article.
October 17, 2016: Ugeskrift for Laeger
Jamshed J Dalal, Anil Dhall, Abhay Bhave
Oral vitamin K antagonists (VKA) such as warfarin have been the mainstay of therapy for stroke prevention in patients with non valvular atrial fibrillation (NVAF) while low-molecular-weight heparin, fondaparinux and adjusted-dose warfarin or aspirin have been routinely used for thromboembolism (VTE) prophylaxis in patients undergoing total hip or knee replacement. However, VKAs are associated with considerable limitations, including increased risk of bleeding and narrow therapeutic window. Novel oral anticoagulants (NOACs, now referred as Non Vit K dependent oral anticoagulants), including the direct thrombin inhibitor dabigatran and direct Factor Xa inhibitors such as rivaroxaban and apixaban are now approved alternatives to warfarin for prophylaxis of stroke and systemic embolic events (SEE) in patients with NVAF and treatment and prophylaxis of VTE...
April 2016: Journal of the Association of Physicians of India
Martina Réblová, Vit Hubka, Olle Thureborn, Johannes Lundberg, Therese Sallstedt, Mats Wedin, Magnus Ivarsson
Rock-inhabiting fungi harbour species-rich, poorly differentiated, extremophilic taxa of polyphyletic origin. Their closest relatives are often well-known species from various biotopes with significant pathogenic potential. Speleothems represent a unique rock-dwelling habitat, whose mycobiota are largely unexplored. Isolation of fungi from speleothem biofilm covering bare granite walls in the Kungsträdgården metro station in Stockholm yielded axenic cultures of two distinct black yeast morphotypes. Phylogenetic analyses of DNA sequences from six nuclear loci, ITS, nuc18S and nuc28S rDNA, rpb1, rpb2 and β-tubulin, support their placement in the Chaetothyriales (Ascomycota)...
2016: PloS One
Vit Weinberger, Marketa Bednarikova, David Cibula, Michal Zikan
Introduction Serous tubal intraepithelial carcinoma (STIC) is most likely precursor lesion of the most part of high-grade serous pelvis carcinomas, carcinosarcoma and undifferentiated carcinoma with incidence of 0.6% to 7% in BRCA carriers or women with strong family history of breast or ovarian carcinoma. STIC is a pathomorphologically and immunohistochemically detectable lesion which biological significance and clinical relevance is unknown. Areas covered We investigate methods of STIC diagnostics and we present an overview of recent studies and available knowledge on surgical management, adjuvant chemotherapy and subsequent follow-up procedure in women with an isolated STIC...
October 12, 2016: Expert Review of Anticancer Therapy
Jae Cheol Kim, Bruce P Mullan, John L Black, Robert J E Hewitt, Robert J van Barneveld, John R Pluske
BACKGROUND: This experiment was conducted to test the hypothesis that vitamin E (Vit E) and acetylsalicylic acid (ASA), a cyclooxygenase-2 (COX-2) inhibitor, will additively reduce the production of the immunosuppressive molecule prostaglandin E2 (PGE2) and hence reduce inflammatory responses in weaner pigs experimentally infected with an enterotoxigenic strain of E. coli. METHODS: The experiment was conducted in a research facility with 192 individually-housed male weaner pigs (Landrace × Large White) weighing 6...
2016: Journal of Animal Science and Biotechnology
Da-Long Guo, Fei-Fei Xi, Yi-He Yu, Xiao-Yu Zhang, Guo-Hai Zhang, Gan-Yuan Zhong
BACKGROUND: Early ripening is an important desirable attribute for fruit crops. 'Kyoho' is a popular table grape cultivar in many Asian countries. 'Fengzao' is a bud mutant of 'Kyoho' and ripens nearly 30 days earlier than 'Kyoho'. To identify genes controlling early fruit development and ripening in 'Fengzao', RNA-Seq profiles of the two cultivars were compared at 8 different berry developmental stages in both berry peel and flesh tissues. METHODS: RNA-Seq profiling of berry development between 'Kyoho' and 'Fenzhao' were obtained using the Illumina HiSeq system and analyzed using various statistical methods...
October 12, 2016: BMC Genomics
Shalini Priya, Abhishek Singh, Sanjay Mehrotra, A Pradhan
No abstract text is available yet for this article.
January 2016: Journal of the Association of Physicians of India
Parmida Beigi, Paul Malenfant, Abtin Rasoulian, Robert Rohling, Alison Dube, Vit Gunka
Current 2-D ultrasound technology is unable to perform a midline neuraxial needle insertion under real-time ultrasound guidance using a standard needle and without an assistant. The aim of the work described here was to determine the feasibility of a new technology providing such capability, starting with a study evaluating the selected puncture site. A novel 3-D ultrasound imaging technique was designed using thick-slice rendering in conjunction with a custom needle guide (3DUS + Epiguide). A clinical feasibility study evaluated the ability of 3DUS + Epiguide to identify the epidural needle puncture site for a midline insertion in the lumbar spine...
October 6, 2016: Ultrasound in Medicine & Biology
T C Mitulescu, C Stavaru, L M Voinea, L M Banica, C Matache, D Predeteanu
Hypothesis:Abnormal Vitamin D (Vit D) level could have consequences on the immuno-inflammatory processes in Ankylosing Spondylitis (AS). Aim:The purpose of this study was to analyze the role of Vitamin D in the interplay between immune and inflammation effectors in AS associated-Acute Anterior Uveitis (AAU). Methods and Results:25-hydroxyvitamin D (Vit D), LL-37 peptide, IL-8 and Serum Amyloid A (SAA) were identified and quantified in the serum/ plasma of thirty-four AS patients [eleven AS patients presenting AAU (AAU AS patients) and twenty-three AS patients without AAU (wAAU AS patients)] and eighteen healthy individuals (Control) using enzyme-linked immunosorbent assay...
January 2016: Journal of Medicine and Life
Changyong Ma, Jiancun Liao, Pengfei Fan
The Cao Vit gibbon (Nomascus nasutus) has only one population with about 110 individuals living in a degraded karst forest along the China-Vietnam border. Investigation of food choice in relation to chemical nutrition will offer important insights into its conservation. We studied the food choice of two groups of Cao Vit gibbons using instantaneous scan sampling in Bangliang National Nature Reserve, Guangxi, China, over 4 years, and analyzed the chemical components (total nitrogen, TN; water-soluble sugar, WSS; crude fat, CF; neutral detergent fiber, NDF; acid detergent fiber, ADF; acid detergent lignin, ADL; condensed tannin, CT; and ash) of 48 food plant parts and 22 non-food plant parts...
October 5, 2016: Primates; Journal of Primatology
Anne Mößeler, Marion Schmicke, Martin Höltershinken, Martin Beyerbach, Josef Kamphues
Pancreatic exocrine insufficiency (PEI) is a disease of diverse aetiology-e.g., majority of patients suffering from cystic fibrosis (CF) show PEI congenitally. Malnutrition and malabsorption of nutrients impair growth and nutritional status. As reduced fat digestion leads to a deficiency of fat-soluble vitamins the supplementation is standard, but absorption is a critical point in PEI-patients. The pancreatic duct ligated (PL) pig is an established model for PEI in humans and has been proven to be a suitable model to compare different vitamin additives for supplementation...
2016: International Journal of Molecular Sciences
Peng-Fei Fan, Chang-Yong Ma, Paul A Garber, Wen Zhang, Han-Lan Fei, Wen Xiao
Dance is a universal art form practiced by all human societies and has many functions including sexual attraction, social cohesion, and the therapeutic release of energy. Dance also has been reported in a small number of non-human primate species, in particular apes. However, its function has not been systematically evaluated. We observed 357 intentional, rhythmic, and nonverbal dance displays performed by four adult female cao vit gibbons (Nomascus nasutus) residing in four polygynous groups during 3000 h of observation in Bangliang, Guangxi, China...
September 30, 2016: Scientific Reports
Jean Sainte-Laudy, François Touraine, Delphine Cluzan, François Belle Moudourou
BACKGROUND: A major problem of venom-specific immunotherapy (VIT) is the absence of reliable parameters for deciding treatment discontinuation. AIM OF THE STUDY: Intracutaneous tests (ICTs), the basophil activation test (BAT), specific IgEs (sIgEs) and blocking factor (BF) activity were measured during VIT. We made an evaluation by means of a protective index (PI) including ICT, BAT and BF values. MATERIAL AND METHODS: A population of 45 patients who had experienced a systemic reaction after an insect sting were tested before VIT (T0), at 1 week (T1w), at 10 weeks (T10w) and at 21 weeks (T21w), and, for a subgroup of 17 patients, at 3-5 years (T3-5y)...
September 30, 2016: International Archives of Allergy and Immunology
Abdulrahman Khazim Al-Asmari, Abdul Quaiyoom Khan, Sarah A Al-Asmari, Abdulqadir Al-Rawi, Saud Al-Omani
BACKGROUND: Intestinal mucositis is a major concern related with cancer therapy. It is well established that overproduction of reactive oxygen species and inflammatory mediators plays vital role in the pathogenesis of mucositis. The aim of the study was to investigate the modulatory effect of vitamin E (vit. E) on 5-fluorouracil (5-FU)-induced intestinal mucositis by targeting oxidative stress and inflammatory markers in rats. METHODS: Rats were randomly divided into four groups of six animals each...
September 2, 2016: Journal of Complementary & Integrative Medicine
Ayse Mese, Joseph Ea Palamara, Rafat Bagheri, Mehdi Fani, Michael F Burrow
This study compared the fracture toughness values of seven resin composites and analyzed the consistency of data values using three methods: compact tension, three point and four point bending for Mode I failure. Seven resin composites were selected: Estellite Sigma Quick, Esthet X HD, Filtek Supreme XTE, Heliomolar, Ice, Rok, and Vit-l-escence. For each material, 18 specimens (n=6 for each test) were prepared. Maximum load to failure was recorded using a universal testing machine and fracture toughness was calculated...
September 29, 2016: Dental Materials Journal
Wei Zhu, Rong Zuo, Rongfang Zhou, Junyan Huang, Minqiang Tang, Xiaohui Cheng, Yueying Liu, Chaobo Tong, Yang Xiang, Caihua Dong, Shengyi Liu
Iron toxicity is a nutrient disorder that severely affects crop development and yield in some soil conditions. Vacuolar detoxification of metal stress is an important strategy for plants to survive and adapt to this adverse environment. Vacuolar iron transporter (VIT) members are involved in this process and play essential roles in iron storage and transport. In this study, we identified a rapeseed VIT gene BnMEB2 (BnaC07g30170D) homologs to Arabidopsis MEB2 (At5g24290). Transient expression analysis revealed that BnMEB2 was localized to the vacuolar membrane...
2016: Frontiers in Plant Science
Vít Procházka, Tomáš Papajík, Andrea Janíková, David Belada, Tomáš Kozák, David Šálek, Alice Sýkorová, Heidi Móciková, Vít Campr, Jitka Dlouhá, Kateřina Langová, Tomáš Fürst, Marek Trněný
Optimal frontline treatment in younger high tumor-burden risk follicular lymphoma patients remains a challenge given the reduced efficacy of standard immunochemotherapy (R-CHOP) in widespread disease and unclear role of intensive induction. The retrospective non-randomized pair-matched (1:3) analysis compared 48 intermediate/high Follicular Lymphoma International Prognostic Index (FLIPI) patients receiving intensive rituximab sequential chemotherapy (R-SQ) with 144 random controls (R-CHOP) matched for age, FLIPI score, and maintenance delivery...
September 25, 2016: Leukemia & Lymphoma
Fatma I Abo El-Ela, S A S Shany, Manal B El-Deen, H A El-Banna, A A El-Gendy, K Hendy, M A Tohamy
Tylvalosin (TVS) is a third-generation macrolide drug used for prophylaxis and treatment of mycoplasma, however; it is supposed to possess an immunosuppressive effect. In the current study, the immunosuppressive effect of TVS and florfenicol (FFC) and the potential immunomodulatory role of Vit E were investigated. The experiment included one day old chick groups treated with either TVS, FFC, Vit E, TVS/Vit E, FFC/Vit E and control non-treated group. Chicks were vaccinated with inactivated H9N2 avian influenza (AI) vaccine and humoral antibody titers to viral antigen as well as innate immunity (serum lysozyme activity and nitric oxide levels) were evaluated...
October 2016: Research in Veterinary Science
Eva Kvasničková, Vít Paulíček, Martina Paldrychová, Richard Ježdík, Olga Maťátková, Jan Masák
The biofilms of filamentous-forming fungi are a novel and still insufficiently understood research topic. We have studied Aspergillus fumigatus, an ubiquitous opportunistic pathogenic fungus, as a representative model for a study of biofilm formation by filamentous fungi and for assessing the potential anti-biofilm activity of natural substances. The activity of antibiotic amphotericin B and selected natural substances: baicalein, chitosan and rhamnolipid was studied. The minimum suspension inhibitory concentrations (MIC) were determined and the biofilm susceptibility was investigated by determining the metabolic activity of sessile cells (XTT assay) and total biofilm biomass (crystal violet staining)...
November 2016: World Journal of Microbiology & Biotechnology
Soroush Safa, Gholamali Moghaddam, Raziallah Jafari Jozani, Hossein Daghigh Kia, Hossein Janmohammadi
This study was conducted to determine the combined effects of adding vitamin E (VitE) and selenium nanoparticle (Nano-Se) as antioxidant supplements to rooster semen extender for freezing. Semen samples were collected from 12 White Leghorn roosters and pooled. Subsequently, the samples were divided into nine equal groups using modified Beltsville extender. Extenders were supplemented with either two amounts of VitE (5 and 10μg/mL) or two amounts of Nano-Se (1% and 2%) or a combination of both VitE and Nano-Se, and no antioxidants extender (control group)...
September 15, 2016: Animal Reproduction Science
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