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Elie Cousin, Ianis Cousin, Karim Aziz, Pascal Chailloux, Estelle Breton
Autoimmune pancreatitis (AIP) is rare in teenagers and difficult to diagnose. There are no clear and established diagnostic criteria in the pediatric population to distinguish subtype 1 and subtype 2. Here, we report the case of a 16-year-old white French teenager admitted to the pediatric emergency service with more than 1 year's history of pain originating from the epigastric and the right hypochondriac regions, with bloody diarrhea. After exclusion of pancreatic cancer and other common causes of acute pancreatitis, the diagnosis of AIP was suspected...
April 2018: Pediatrics
Magaly Zappa, Sabrina Doblas, Dominique Cazals-Hatem, Fabien Milliat, Jérémy Lavigne, Fanny Daniel, Abelhak Jallane, Philippe Garteiser, Valérie Vilgrain, Eric Ogier-Denis, Bernard E Van Beers
Murine radiation-induced rectocolitis is considered to be a relevant animal model of gastrointestinal inflammation. The purpose of our study was to compare quantitative MRI and histopathological features in this gastrointestinal inflammation model. Radiation rectocolitis was induced by localized single-dose radiation (27 Gy) in Sprague-Dawley rats. T2 -weighted, T1 -weighted and diffusion-weighted MRI was performed at 7 T in 16 rats between 2 and 4 weeks after irradiation and in 10 control rats. Rats were sacrificed and the histopathological inflammation score of the colorectal samples was assessed...
April 2018: NMR in Biomedicine
Edris Wedi, Beatrice Orlandini, Mark Gromski, Carlo Felix Maria Jung, Irina Tchoumak, Stephanie Boucher, Volker Ellenrieder, Jürgen Hochberger
The full-thickness resection device (FTRD) is a novel endoscopic device approved for the resection of colorectal lesions. This case-series describes the device and its use in high-risk patients with colorectal lesions and provides an overview of the potential indications in recently published data. Between December 2014 and September 2015, 3 patients underwent endoscopic full thickness resection using the FTRD for colorectal lesions: 1 case for a T1 adenocarcinoma in the region of a surgical anastomosis after recto-sigmoidectomy, 1 case for a non-lifting colonic adenoma with low-grade dysplasia in an 89-year old patient and 1 for a recurrent adenoma with high-grade dysplasia in a young patient with ulcerative rectocolitis who was under immunosuppression after renal transplantation...
January 2018: Clinical Endoscopy
Benjamin Darnis, Gilles Poncet, Maud Robert
Ulcero-haemorrhagic rectocolitis can occur after liver transplantation for sclerosing cholangitis. Total colectomy with or without proctectomy may be indicated in case of chronic drug-resistant colitis, dysplasia or cancer. Today, laparoscopic approach is the standard for such procedure in non-operated patients. We performed a completely laparoscopic total colectomy 5 years after a liver transplantation. There were a few peritoneal adherences, and we could safely perform the procedure almost as usual. It provided all the advantages of the laparoscopic approach in the post-operative course...
July 2017: Journal of Minimal Access Surgery
Lucia Monti, Rosamaria Servillo, Irene Grazzini, Leila Khader, Maurizio Acampa, Alfonso Cerase
BACKGROUND: Takayasu arteritis (TA), also known as aortoarteritis and pulseless disease, is an autoimmune, idiopathic, large-vessel vasculitis that primarily affects the aorta and its major branches, the coronary arteries, and the pulmonary arteries. METHODS: This is a peculiar clinical and radiological pattern of TA in a young female Caucasian. Her medical history included diagnosis of ulcerative rectocolitis at the age of 14. Because of the occurrence of anemia and exacerbation of rectocolitis, she had started infliximab associated with low doses of cortisone and mesalazine...
July 2017: Journal of Stroke and Cerebrovascular Diseases: the Official Journal of National Stroke Association
Gilton Marques dos Santos, Luciana Rodrigues Silva, Genoile Oliveira Santana
OBJECTIVE: To perform a systematic review of the literature about the nutritional impact of inflammatory bowel diseases in children and adolescents. DATA SOURCES: A systematic review was performed using PubMed/MEDLINE, LILACS and SciELo databases, with inclusion of articles in Portuguese and in English with original data, that analyzed nutritional aspects of inflammatory bowel diseases in children and adolescents. The initial search used the terms "inflammatory bowel diseases" and "children" or "adolescents" and "nutritional evaluation" or "nutrition deficiency"...
December 2014: Revista Paulista de Pediatria: Orgão Oficial da Sociedade de Pediatria de São Paulo
Yumi Cristina Komatsu, Gabriela Cunha Capareli, Maria Fernanda Feitosa de Camargo Boin, Rute Lellis, Thaís Helena Proença de Freitas, Karine Simone
Inflammatory bowel diseases can commonly present many cutaneous lesions which can contribute to the diagnosis of the disease or its activity. The most frequent cutaneous or mucocutaneous manifestations suggesting ulcerative rectocolitis activity are erythema nodosum (3-10%), pyoderma gangrenosum (5-12%) and aphthous stomatitis (4%). Other reactive skin manifestations related to immunological mechanisms associated with the inflammatory bowel disease are: Sweet's syndrome, arthritis-dermatitis syndrome associated with inflammatory bowel disease and leukocytoclastic vasculitis...
November 2014: Anais Brasileiros de Dermatologia
Estelle Jean, Mikael Ebbo, Sophie Valleix, Lucas Benarous, Laurent Heyries, Aurélie Grados, Emmanuelle Bernit, Gilles Grateau, Thomas Papo, Brigitte Granel, Laurent Daniel, Jean-Robert Harlé, Nicolas Schleinitz
BACKGROUND: Systemic amyloidoses is a heterogeneous group of diseases either acquired or hereditary. Amyloidoses can involve the gastrointestinal tract and the nature of the precursor protein that forms the fibrils deposits should be identified to adjust the treatment and evaluate the prognosis. Lysozyme amyloidosis (ALys) is a rare, systemic non neuropathic hereditary amyloidosis with a heterogenous phenotype including gastrointestinal, renal and hepatic symptoms. CASE PRESENTATION: We report and describe symptoms and gastrointestinal tract involvement in a new family with hereditary lysozyme amyloidosis...
2014: BMC Gastroenterology
N Vietti Violi, Naïk Vietti Violi, Alain M Schoepfer, Nicolas Fournier, Boris Guiu, Pierre Bize, Alban Denys
OBJECTIVE: The purpose of this study was to evaluate the prevalence of mesenteric venous thrombosis (MVT) in the Swiss Inflammatory Bowel Disease Cohort Study and to correlate MVT with clinical outcome. MATERIALS AND METHODS: Abdominal portal phase CT was used to examine patients with inflammatory bowel disease (IBD). Two experienced abdominal radiologists retrospectively analyzed the images, focusing on the superior and inferior mesenteric vein branches and looking for signs of acute or chronic thrombosis...
July 2014: AJR. American Journal of Roentgenology
Stefano Miniello, Rinaldo Marzaioli, Mario Giosué Balzanelli, Caterina Dantona, Anna Stella Lippolis, Diana Barnabà, Michele Nacchiero
Toxic megacolon is a clinical condition associated to high risk of colonic perforation, that significantly increases--even triplicates--the megacolon-related mortality when causing diffuse peritonitis. Abdominal and pelvic helical CT scan proved to be a fundamental diagnostic tool, in defining the colic dilatation and perforation. Conservative treatment is initially indicated in the event of toxic megacolon arising at the onset of a severe or toxic colitis. However it should be avoided when the toxic megacolon appears on corticosteroid therapy...
January 2014: Annali Italiani di Chirurgia
Mario F Chammas, Anuar I Mitre, Nicolas Hubert, Christophe Egrot, Jacques Hubert
BACKGROUND AND OBJECTIVES: We aimed to assess the feasibility and outcomes of complex ureteropelvic junction obstruction cases submitted to robotic-assisted laparoscopic pyeloplasty. METHODS: The records of 131 consecutive patients who underwent robotic-assisted laparoscopic pyeloplasty were reviewed. Of this initial population of cases, 17 were considered complex, consisting of either atypical anatomy (horseshoe kidneys in 3 patients) or previous ureteropelvic junction obstruction management (14 patients)...
January 2014: JSLS: Journal of the Society of Laparoendoscopic Surgeons
Gustavo G Resende, Cristina C D Lanna, Adriana B Bortoluzzo, Célio R Gonçalves, José Antonio Braga da Silva, Antonio Carlos Ximenes, Manoel B Bértolo, Sandra L E Ribeiro, Mauro Keiserman, Rita Menin, Thelma L Skare, Sueli Carneiro, Valderílio F Azevedo, Walber P Vieira, Elisa N Albuquerque, Washington A Bianchi, Rubens Bonfiglioli, Cristiano Campanholo, Hellen M S Carvalho, Izaias P Costa, Angela P Duarte, Charles L Kohem, Nocy Leite, Sonia A L Lima, Eduardo S Meirelles, Ivânio A Pereira, Marcelo M Pinheiro, Elizandra Polito, Francisco Airton C Rocha, Mittermayer B Santiago, Maria de Fátima L C Sauma, Valeria Valim, Percival D Sampaio-Barros
UNLABELLED: Inflammatory bowel diseases (Crohn's disease and ulcerative rectocolitis) have extraintestinal manifestations 25% of the patients, with the most common one being the enteropathic arthritis. METHODS: Prospective, observational, multicenter study with patients from 29 reference centers participating in the Brazilian Registry of Spondyloarthritis (RBE), which incorporates the RESPONDIA (Ibero-American Registry of Spondyloarthritis) group. Demographic and clinical data were collected from 1472 patients and standardized questionnaires for the assessment of axial mobility, quality of life, enthesitic involvement, disease activity and functional capacity were applied...
November 2013: Revista Brasileira de Reumatologia
Alvaro Mitsunori Nishikawa, Luciano Paladini, Régis Delfini, Paulo Gustavo Kotze, Otavio Clark
CONTEXT: Unspecified Ulcerative Rectocolitis is a chronic disease that affects between 0.5 and 24.5/105 inhabitants in the world. National and international clinical guidelines recommend the use of aminosalicylates (including mesalazine) as first-line therapy for induction of remission of unspecified ulcerative rectocolitis, and recommend the maintenance of these agents after remission is achieved. However, multiple daily doses required for the maintenance of disease remission compromise compliance with treatment, which is very low (between 45% and 65%)...
October 2013: Arquivos de Gastroenterologia
Wilmara Salgado-Pabón, Susanna Celli, Ellen T Arena, Katharina Nothelfer, Pascal Roux, Gernot Sellge, Elisabetta Frigimelica, Philippe Bousso, Philippe J Sansonetti, Armelle Phalipon
The Gram-negative enteroinvasive bacterium Shigella flexneri is responsible for the endemic form of bacillary dysentery, an acute rectocolitis in humans. S. flexneri uses a type III secretion system to inject effector proteins into host cells, thus diverting cellular functions to its own benefit. Protective immunity to reinfection requires several rounds of infection to be elicited and is short-lasting, suggesting that S. flexneri interferes with the priming of specific immunity. Considering the key role played by T-lymphocyte trafficking in priming of adaptive immunity, we investigated the impact of S...
March 19, 2013: Proceedings of the National Academy of Sciences of the United States of America
Manola Comar, Serena Delbue, Loredana Lepore, Stefano Martelossi, Oriano Radillo, Luca Ronfani, Pierlanfranco D'Agaro, Pasquale Ferrante
Treatment with biological drugs is associated with increased susceptibility to viral infections. Reactivation of JC virus (JCV) and human cytomegalovirus (HCMV) in adults after therapy has been documented. The long-term effects of biological and conventional therapy on human herpesviruses and polyomaviruses infections in young patients were assessed. One hundred eighty-six samples [urine, serum, and blood cells (PBMCs)] from 62 patients (15.8 ± 6.2 years old) with Crohn's disease, ulcerative rectocolitis or juvenile rheumatoid arthritis treated with immunotherapy or conventional therapy for over 12 months were tested by real time PCR...
April 2013: Journal of Medical Virology
Amel Mebazaa, Amina Aounallah, Narjess Naija, Rim Cheikh Rouhou, Lamia Kallel, Dalenda El Euch, Jalel Boubaker, Mourad Mokni, Azza Filali, Amel Ben Osman
BACKGROUND: Cutaneous manifestations are the most common extra intestinal manifestations associated with inflammatory bowel disease (IBD). AIM: To assess the epidemio-clinical profile of skin manifestations in IBD. METHODS: A prospective and descriptive study was conducted. We have examined skin, mucosa, hair and nails, of all patients with an IBD during one year. RESULTS: One hundred-ninety-five patients were included...
March 2012: La Tunisie Médicale
Klaus Pantel, Eric Denève, David Nocca, Amandine Coffy, Jean-Pierre Vendrell, Thierry Maudelonde, Sabine Riethdorf, Catherine Alix-Panabières
BACKGROUND: Detection of circulating tumor cells (CTCs) in the peripheral blood is a rapidly developing research field with clear clinical implications for the staging and monitoring of cancer patients. Current CTC assays, including the US Food and Drug Administration-cleared CellSearch® system, typically use markers [e.g., cytokeratins (CKs), the transmembrane protein EpCAM (epithelial cell adhesion molecule)] that are expressed on normal and malignant epithelial cells but not on the surrounding normal leukocytes...
May 2012: Clinical Chemistry
M Durazzo, M Spandre, P Belci, E Paschetta, A Premoli, S Bo
In opposition to opinions of a sectorialization of psychiatric illness, phenomena of comorbidity due to susceptibility of psychiatric patients to contract other diseases--whose co-presence is difficult to translate and treat--are more and more evident. In this review we have marked main issues of internal medicine in psychiatric patients. This review will discuss particularly main cardiovascular diseases (CAD, VTE), lung diseases (COPD,asthma, restrictive lung disease) gastroenterologic disease (IBS, coeliac disease, ulcerous rectocolitis), diabetes and metabolic syndrome, more likely infections verified in these patients (HIV, viral hepatitis), cancers considerably underlined (breast cancer, colon-rectal cancer and lung cancer), internistic issues in alcohol abuse which is a frequent state in these subjects...
October 2010: Minerva Medica
A Busson, J Chomé
No abstract text is available yet for this article.
February 1966: Proceedings of the Royal Society of Medicine
M Pirşcoveanu, M Munteanu, P Mănescu, A Ruxanda, L Vasile, St Dina, N Pogoran, D Mănescu, C Tudoraşcu, S Fulger, L Drăguşin
The gastrointestinal stromal tumors (GIST) are the rares mesenchymal tumors of the gastrointestinal tract (1-3% of all gastrointestinal neoplasias). The frequency of their location on the rectocolic site is quoted with the values lower than 10% of all GIST. The authors present a patient case 55 years aged, who presented a gastrointestinal stromal tumor cecal located. This tumor determined the invagination of the cec into the ascendent colon and then into transverse colon drawing the last ileal ansa and leading to an ileo-cecal-colic invagination, without development of a occlusive syndrome...
May 2010: Chirurgia
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