keyword
https://read.qxmd.com/read/38344051/an-appy-that-needs-epi-an-atypical-presentation-of-anaphylaxis
#1
JOURNAL ARTICLE
Ryan O'Neill, Cyrus Adeli, Christopher E San Miguel
AUDIENCE: This simulation is intended for 4th year medical students. BACKGROUND: Shock is the result of inadequate circulation and failure to perfuse tissues, leading to cellular and organ dysfunction.1 Anaphylactic shock specifically is a type of distributive shock secondary to an IgE (immunoglobulin E) dependent reaction, which can result in respiratory compromise and cardiovascular collapse. The National Institute of Allergy and Infectious Diseases/Food Allergy and Anaphylaxis Network (NIAID/FAAN) laid out three diagnostic criteria for the diagnosis of anaphylaxis...
January 2024: Journal of education & teaching in emergency medicine
https://read.qxmd.com/read/38261548/fatal-case-of-exercise-collapse-associated-with-sickle-cell-trait-with-novel-underlying-lama2-mutation
#2
JOURNAL ARTICLE
Couger Jimenez Jaramillo, Thomas Gibbons, Rachel Rose, John Walsh
Sickle cell trait is typically thought to be an asymptomatic carrier state, but it is rarely associated with exertional rhabdomyolysis in cases termed Exercise Collapse Associated with Sickle Cell Trait (ECAST). In a subset of these cases, underlying disease contributes to the development and/or severity of the ensuing medical complications. We describe the first ever case of ECAST reported in a previously asymptomatic, multiply deployed, highly physically active service member with an underlying heterozygous LAMA2 mutation...
January 23, 2024: American Journal of Forensic Medicine and Pathology
https://read.qxmd.com/read/38086174/standing-left-recurrent-laryngeal-neurectomy-for-prospective-evaluation-of-laryngeal-hemiplegia-evaluated-by-a-high-speed-treadmill-test
#3
JOURNAL ARTICLE
Natasha E Lean, Samantha H Franklin, Benjamin J Ahern
OBJECTIVE: To describe left recurrent laryngeal neurectomy (LRLn) performed under standing sedation and evaluate the effect of LRLn on upper respiratory tract function using a high-speed treadmill test (HST). We hypothesized that (1) unilateral LRLn could be performed in standing horses, resulting in ipsilateral arytenoid cartilage collapse (ACC); and (2) HST after LRLn would be associated with alterations in upper respiratory function consistent with dynamic ACC. ANIMALS: 6 Thoroughbred horses...
December 16, 2023: American Journal of Veterinary Research
https://read.qxmd.com/read/37919145/an-unusual-case-of-marathon-related-exercise-associated-collapse-case-report-and-some-considerations-for-medical-care-at-endurance-mass-participation-events
#4
JOURNAL ARTICLE
Luca Carenzo, Federico Emiliano Ghio, Nicholas Mariani, Paolo Emilio Adami, Maurizio Cecconi, Sara Bonizzato
This article presents a unique exercise-associated collapse case during a marathon, highlighting the significance of evidence-based management for athletes on field. The patient, a 61-year-old experienced runner, collapsed near the finish line of the Milano City Marathon. He was aided immediately with CPR and AED. After excluding, through validated algorithms, common and life-threatening causes of collapse, the patient was transferred to hospital. The patient underwent diagnostic procedures, including CT and MRI scans, and hormonal tests that revealed pituitary hemorrhage and underlying coronary artery disease...
October 20, 2023: Journal of Science and Medicine in Sport
https://read.qxmd.com/read/37865154/upper-airway-endoscopy-in-exercising-horses-findings-in-164-barrel-racing-horses-with-respiratory-clinical-signs-and-or-poor-performance
#5
JOURNAL ARTICLE
S L Massie, R Léguillette
Barrel racing involves sprinting through a cloverleaf pattern in under 20s. The prevalence of upper airway obstructions (UAO) in barrel racers is unknown, thus a retrospective analysis of 164 client-owned horses referred for overground endoscopy (OGE) between 2014-2022 was performed. Referring complaints included respiratory noise, cough, epistaxis, behaviour (owner reported stress/anxiety, refusal to enter arena, excessive head shaking), and/or poor performance. Horses performed a standardized exercise test with low and high-speed components...
October 19, 2023: Veterinary Journal
https://read.qxmd.com/read/37815277/fat-free-mass-index-in-a-large-sample-of-national-collegiate-athletic-association-men-and-women-athletes-from-a-variety-of-sports
#6
JOURNAL ARTICLE
Meghan K Magee, Jennifer B Fields, Andrew R Jagim, Margaret T Jones
Magee, MK, Fields, JB, Jagim, AR, and Jones, MT. Fat-free mass index in a large sample of National Collegiate Athletic Association men and women athletes from a variety of sports. J Strength Cond Res XX(X): 000-000, 2023-Fat-free mass index (FFMI) can be used to categorize fat-free mass (FFM) relative to height. Normative values have been established in a variety of sports, as has suggested lower and upper thresholds of FFMI. However, FFMI has not been reported in a large sample of athletes, representing both sexes and multiple sport types...
October 6, 2023: Journal of Strength and Conditioning Research
https://read.qxmd.com/read/37457924/pneumatic-stenting-in-the-surgical-candidacy-assessment-for-cough-variant-expiratory-central-airway-collapse
#7
Alanna Barrios-Ruiz, Alejandra Yu Lee-Mateus, Britney N Hazelett, Katherine L Walsh, Sebastian Fernandez-Bussy, Vichaya Arunthari, Brendon Colaco, Bryan J Taylor, David Abia-Trujillo
Expiratory Central Airway Collapse (ECAC) is a multifactorial, underdiagnosed entity that poses unique challenges. Airway stenting is used as a predictor for successful outcomes after central airway stabilization surgery via tracheobronchoplasty (TBP). This approach may pose suboptimal performance in certain ECAC variants. We hypothesize that Continuous Positive Airway Pressure (CPAP), used as a pneumatic stent, could be a non-invasive alternative to evaluate surgical candidacy in cough-predominant ECAC presentations...
2023: Respiratory Medicine Case Reports
https://read.qxmd.com/read/37449573/splanchnic-nerve-modulation-effects-on-surrogate-measures-of-venous-capacitance
#8
JOURNAL ARTICLE
Veraprapas Kittipibul, Arun Ganesh, Aubrie Coburn, Brian J Coyne, James Matthew Gray, Jeroen Molinger, Neil Ray, Mihai Podgoreanu, Sharon L McCartney, Negmeldeen Mamoun, Robert Curtis Fitzhugh, Philipp Lurz, Cynthia L Green, Adrian F Hernandez, Manesh R Patel, Marat Fudim
Background Splanchnic nerve modulation (SNM) is an emerging procedure to reduce cardiac filling pressures in heart failure. Although the main contributor to reduction in cardiac preload is thought to be increased venous capacitance in the splanchnic circulation, supporting evidence is limited. We examined changes in venous capacitance surrogates pre- and post-SNM. Methods and Results This is a prespecified analysis of a prospective, open-label, single-arm interventional study evaluating the effects of percutaneous SNM with ropivacaine in chronic heart failure with elevated filling pressures at rest and with exercise...
July 18, 2023: Journal of the American Heart Association
https://read.qxmd.com/read/37378586/sudden-cardiac-death-in-a-young-male-endurance-athlete
#9
Kevin D Seely, Kentlee B Crockett, Andrew Nigh
Sudden cardiac death (SCD) is a rare yet devastating event that can occur in young athletes. Although hypertrophic obstructive cardiomyopathy is the most common cause of SCD, some other genetic abnormalities have been identified as proarrhythmic. However, there is not routine screening for these other genetic abnormalities. Furthermore, consumption of caffeine, stimulant medication, or prolonged exercise can potentiate the underlying arrhythmic potential. In the event of SCD, advanced cardiac life support (ACLS) should be performed immediately and exactly...
June 29, 2023: Journal of osteopathic medicine
https://read.qxmd.com/read/37289864/-heat-illness
#10
JOURNAL ARTICLE
Amber E Hoek, Nathalie Dollee, Gerrie Prins, Jelmer Alsma
Thermoregulation keeps the normal body temperature of humans at approximately 37 °C. However, as a result of heat load - both endogenous and exogenous heat - it can occur that the body is unable to dissipate excess heat, leading to an increase in the core body temperature. This can result in various heat illnesses, ranging from mild, non-life-threatening conditions, such as heat rash, heat edema, heat cramps, heat syncope and exercise associated collapse to life-threatening conditions, namely exertional heatstroke and classic heatstroke...
May 31, 2023: Nederlands Tijdschrift Voor Geneeskunde
https://read.qxmd.com/read/37068709/calf-muscle-pump-pressure-flow-cycle-during-ambulation
#11
JOURNAL ARTICLE
Roman A Tauraginskii, Fedor Lurie, Sergei Simakov, Rishal Agalarov, Denis Borsuk, Pavel Khramtsov
OBJECTIVE: Calf muscle pump (CMP) failure contributes to the severity and progression of chronic venous disease. Attempts to improve CMP function through resistance exercise have failed to improve chronic venous disease severity or quality of life, partially because the selection of the type of exercise was based on the assumption that the CMP ejects blood from the intramuscular venous sinuses (VSs), which has never been tested in humans. In the present study, we investigated the real-time changes in the pressure and size of the VS during the entire gait cycle of ambulation...
April 15, 2023: Journal of Vascular Surgery. Venous and Lymphatic Disorders
https://read.qxmd.com/read/36557060/characteristics-and-future-direction-of-tibialis-posterior-tendinopathy-research-a-scoping-review
#12
REVIEW
Hye Chang Rhim, Ravi Dhawan, Ashley E Gureck, Daniel E Lieberman, David C Nolan, Ramy Elshafey, Adam S Tenforde
Background and Objectives : Tibialis posterior tendon pathologies have been traditionally categorized into different stages of posterior tibial tendon dysfunction (PTTD), or adult acquired flatfoot deformity (AAFD), and more recently to progressive collapsing foot deformity (PCFD). The purpose of this scoping review is to synthesize and characterize literature on early stages of PTTD (previously known as Stage I and II), which we will describe as tibialis posterior tendinopathy (TPT). We aim to identify what is known about TPT, identify gaps in knowledge on the topics of TPT, and propose future research direction...
December 16, 2022: Medicina
https://read.qxmd.com/read/36340820/non-cpap-therapy-for-obstructive-sleep-apnoea
#13
REVIEW
Johan Verbraecken, Marijke Dieltjens, Sara Op de Beeck, Anneclaire Vroegop, Marc Braem, Olivier Vanderveken, Winfried Randerath
UNLABELLED: Treatment of obstructive sleep apnoea in adults is evolving, from a "one treatment fits all" to a more individualised approach. The spectrum of treatment options is broad and heterogeneous, including conservative, technological and pharmaceutical modalities. This raises the questions of which patients these modalities might be useful for, and if there are specific criteria for single or combined treatment. The most commonly used non-CPAP treatment is a mandibular advancement device...
September 2022: Breathe
https://read.qxmd.com/read/36332888/assessment-of-flow-mechanics-in-the-lower-extremity-venous-system
#14
JOURNAL ARTICLE
Taimur Saleem, Thomas Powell, William Walker, Seshadri Raju
BACKGROUND: The Reynolds number (Re ) is a dimensionless parameter that describes fluid flow mechanics. Veins are compliant and collapsible vascular conduits that can accommodate large volume changes in response to small pressure changes. However, only sparse information is available about flow parameters such as the Re in the venous system. METHODS: Bilateral duplex ultrasound examination of 15 healthy volunteers (30 limbs) was performed before and after exercise (four flights of stairs) of the veins of the lower extremity (left and right sides) and inferior vena cava...
November 2, 2022: Journal of Vascular Surgery. Venous and Lymphatic Disorders
https://read.qxmd.com/read/35943919/association-between-dynamic-upper-airway-obstructions-and-fitness-parameters-in-standardbred-racehorses-during-high-speed-treadmill-exercise
#15
JOURNAL ARTICLE
Chiara M Lo Feudo, Luca Stucchi, Pietra Cavicchioli, Giovanni Stancari, Bianca Conturba, Enrica Zucca, Francesco Ferrucci
OBJECTIVE: To evaluate the association between the severity of dynamic upper airway obstruction (DUAO) and selected fitness parameters in Standardbred racehorses measured by treadmill test. ANIMALS: 191 Standardbred racehorses that underwent a standardized diagnostic protocol for poor performance evaluation between 2002 and 2021 at the Veterinary Teaching Hospital, University of Milan. PROCEDURES: Horses underwent a diagnostic protocol including clinical examination, lameness evaluation, laboratory analyses, ECG, resting upper airway endoscopy, metabolic incremental treadmill test, high-speed treadmill endoscopy, postexercise tracheobronchoscopy, and bronchoalveolar lavage fluid cytology...
May 27, 2022: Journal of the American Veterinary Medical Association
https://read.qxmd.com/read/35877561/myocardial-bridging-leading-to-cardiac-collapse-in-a-marathon-runner
#16
André Alexandre, Pinheiro Vieira, André Dias-Frias, Anaisa Pereira, Andreia Campinas, David Sá-Couto, Bruno Brochado, Isabel Sá, João Silveira, Severo Torres
Myocardial bridging (MB) is a congenital coronary anomaly, which is defined as cardiac muscle overlying a portion of a coronary artery. Although traditionally considered benign in nature, increasing attention is being given to specific subsets of MB. Sports medicine recognizes MB as a cause of sudden death among young athletes. We present a case of a 30-year-old man who suddenly collapsed during a marathon running. Diagnostic workup with coronary computed tomography angiography revealed the presence of three simultaneous myocardial bridges in this patient, possibly explaining the exercise-induced syncope...
June 24, 2022: Journal of Cardiovascular Development and Disease
https://read.qxmd.com/read/35766201/the-combined-outcomes-of-the-covid-19-pandemic-and-a-collapsing-economy-on-mental-well-being-a-cross-sectional-study
#17
JOURNAL ARTICLE
Hala Sacre, Aline Hajj, Danielle A Badro, Carla Abou Selwan, Chadia Haddad, Randa Aoun, Pascale Salameh
Objective: This study aimed to examine the outcomes of COVID-19 and a collapsing economy on the mental well-being (MWB) of the general Lebanese population. Methods: A cross-sectional study was conducted online in May 2020 and enrolled 502 adults. Results: Mental well-being had a mean of 14.80 (14.37; 15.24). A lower MWB was associated with female gender (beta=-1.533 [-2.324; -0.743]), university education (beta=-2.119 [-3.353;-0.885]), fear of COVID-19 (beta=-0.131 [-0.199; -0.063]), fear of poverty (beta=-0...
June 29, 2022: Psychological Reports
https://read.qxmd.com/read/35749087/pulmonary-atelectasis-in-a-young-dog-with-cor-pulmonale-clinical-and-radiographic-follow-up
#18
Diana do Amaral Mendonça, Sophie Ballot, Dianna Caroline Saiki, Gabrielly Ferreira Santos, Laércio Correia Fernandes, Caroline de Oliveira Amorim, Alexandre José Rodrigues Bendas, Bruno Alberigi
Pulmonary atelectasis is a disease characterized by the collapse of the pulmonary alveoli, leading to partial or total loss of function in the affected lung, and is mostly described in older dogs. It occurs due to chronic inflammatory and obstructive processes such as pneumonia. In infants who do not feed directly from the mother, it is common to develop aspiration pneumonia due to inhalation of a milk replacer. Once aspirated, food generates an inflammatory process in the airway that alters the function of the pulmonary surfactant, increases mucus production, and causes consequent airway obstruction, which may progress to alveolar and bronchial collapse...
2022: Revista Brasileira de Medicina Veterinaria
https://read.qxmd.com/read/35555332/characterization-of-carm1-inhibition-in-skeletal-muscle
#19
JOURNAL ARTICLE
Erin K Webb, Sean Y Ng, Derek W Stouth, Tiffany L van Lieshout, Andrew I Mikhail, Vladimir Ljubicic
Coactivator-associated arginine methyltransferase 1 (CARM1) catalyzes the methylation of arginine residues of target proteins critical for health and disease. CARM1 has recently emerged as an important regulator of skeletal muscle biology. The purpose of this study was to further investigate CARM1 biology in skeletal muscle. For our first experiment, we utilized 3-month-old male and female mice (n = 3/sex) that were housed and cared for in accordance with Canadian Council for Animal Care guidelines. Mice were treated with either a CARM1 inhibitor (150 mg/kg EZM2302; Epizyme, Inc...
May 2022: FASEB Journal: Official Publication of the Federation of American Societies for Experimental Biology
https://read.qxmd.com/read/35522441/sickle-cell-trait-at-high-altitudes-as-a-response-to-summit-on-exercise-collapse-associated-with-sickle-cell-trait-finding-the-way-ahead
#20
JOURNAL ARTICLE
LaTraia S Scott
No abstract text is available yet for this article.
May 1, 2022: Current Sports Medicine Reports
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