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Therapeutic endoscopy

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https://www.readbyqxmd.com/read/29666667/impact-of-the-timing-of-capsule-endoscopy-in-overt-obscure-gastrointestinal-bleeding-on-yield-and-rebleeding-rate-is-sooner-than-14-d-advisable
#1
Catarina Gomes, Rolando Pinho, Adélia Rodrigues, Ana Ponte, Joana Silva, Jaime Pereira Rodrigues, Mafalda Sousa, João Carlos Silva, João Carvalho
AIM: To evaluate the impact of the timing of capsule endoscopy (CE) in overt-obscure gastrointestinal bleeding (OGIB). METHODS: Retrospective, single-center study, including patients submitted to CE in the setting of overt-OGIB between January 2005 and August 2017. Patients were divided into 3 groups according to the timing of CE (≤ 48 h; 48 h-14 d; ≥ 14 d). The diagnostic and therapeutic yield (DY and TY), the rebleeding rate and the time to rebleed were calculated and compared between groups...
April 16, 2018: World Journal of Gastrointestinal Endoscopy
https://www.readbyqxmd.com/read/29662295/should-hot-biopsy-forceps-be-abandoned-for-polypectomy-of-diminutive-colorectal-polyps
#2
Vasileios Panteris, Antonios Vezakis, J K Triantafillidis
Standardized approach to polypectomy of diminutive colorectal polyps (DCPs) is lacking since cold biopsy forceps have been associated with high levels of recurrence, hot biopsy forceps are considered inadequate and risky and cold snaring is currently under investigation for its efficacy and safety. This has led to confusion and a gap in clinical practice. This article discusses the usefulness and contemporary practical applicability of hot biopsy forceps and provides well-intentioned criticism of the new European guidelines for the treatment of DCPs...
April 14, 2018: World Journal of Gastroenterology: WJG
https://www.readbyqxmd.com/read/29658639/endoscopic-full-thickness-resection-for-gastrointestinal-submucosal-tumors
#3
REVIEW
Ming-Yan Cai, Francisco Martin Carreras-Presas, Ping-Hong Zhou
Endoscopic full-thickness resection (EFTR) is a "changing-concept" endoscopic resection technique, which safely allows resecting deep submucosal tumors (SMTs) in the gastrointestinal (GI) wall. It's a highly promising endoscopic procedure that allows full-thickness excision of a small piece of the complete GI wall by using only a flexible endoscope. EFTR is a meeting point between surgery and endoscopy and probably the onset of many prospective combined minimally invasive therapeutic techniques that science will explore...
April 2018: Digestive Endoscopy: Official Journal of the Japan Gastroenterological Endoscopy Society
https://www.readbyqxmd.com/read/29644509/applications-of-colon-capsule-endoscopy
#4
REVIEW
Shabana F Pasha
PURPOSE OF REVIEW: This is a review of colon capsule endoscopy (CCE) with a focus on its recent developments, technological improvements, and current and potential future indications. RECENT FINDINGS: Based on the current literature, CCE II demonstrates comparable polyp detection rates as optical colonoscopy and CT colonography, and improved cost-effectiveness. The main limitation to patient acceptance is the requirement of a rigorous bowel preparation. Preliminary studies show good correlation between CCE and optical colonoscopy for assessment of colonic disease activity in inflammatory bowel disease (IBD)...
April 12, 2018: Current Gastroenterology Reports
https://www.readbyqxmd.com/read/29643870/therapeutic-endoscopy-in-combination-with-quadruple-therapy-in-treating-bleeding-caused-by-gastric-ulcer
#5
Yuqin Zuo, Shuhui Wang, Xiujuan Cui, Hongna Lv
Objective: To analyze the efficacy of therapeutic endoscopy in combination with quadruple therapy in treating bleeding caused by gastric ulcer and investigate the factors inducing rebleeding. Methods: Two hundred and twelve patients with bleeding caused by gastric ulcer who were admitted to Binzhou People's Hospital, Shandong, China between April 2015 and April 2016 were selected as research subjects. The patients were randomly divided into a control group and an experimental group...
January 2018: Pakistan Journal of Medical Sciences Quarterly
https://www.readbyqxmd.com/read/29643728/use-of-otoscope-as-a-diagnostic-and-therapeutic-aid-in-umbilical-pilonidal-sinus-a-novel-technique
#6
Farhanul Huda, Sudhir Kumar Singh
Introduction: Umbilical disorders are frequently encountered in general surgical practice. Although the sacrococcygeal region is the most common site for pilonidal sinus disease, it can be seen occasionally in periumbilical area. Treatment is mostly conservative for umbilical pilonidal sinus in contrast to the sacrococcygeal sinus where it is always surgical. In the era of endoscopy and minimally invasive surgery, we describe the use of otoscope as a novel technique for the diagnosis and treatment of umbilical pilonidal sinus...
January 2018: Nigerian Journal of Surgery: Official Publication of the Nigerian Surgical Research Society
https://www.readbyqxmd.com/read/29629057/etiology-of-gastrointestinal-bleeding-in-children-referred-to-pediatric-wards-of-mashhad-hospitals-iran
#7
Seyed Ali Jafari, Mohammad Ali Kiani, Hamid Reza Kianifar, Mohammad Mansooripour, Elahe Heidari, Maryam Khalesi
Background: Gastrointestinal (GI) bleeding, which has several clinical manifestation and origins, is known as one of the most life-threatening events in children. Several etiologies have been suggested for GI bleeding. Objective: To determine the most important causes of GI bleeding in children referred to Ghaem Hospital and Dr. Sheikh Hospital, Mashhad, Iran. Methods: In this cross-sectional study, after obtaining written informed consent of their parents, 113 patients aging from newborn infants to 18-year-old children with GI bleeding admitted to Ghaem Hospital and Dr...
February 2018: Electronic Physician
https://www.readbyqxmd.com/read/29620627/small-bowel-capsule-endoscopy-indications-results-and-clinical-benefit-in-a-university-environment
#8
Juliane Flemming, Silke Cameron
Capsule endoscopy (CE) opened a new method for visualization of the small intestine. We here further explore its clinical implications.We retrospectively analyzed the clinical benefit of CE in view of medical history, diagnostics, and therapy. Our patient collective consisted of 203 patients. CE was investigated in the context of bleeding, anemia, abdominal pain, diarrhea, Crohn's disease, and suspected tumors.The study collective consisted of 118 male and 85 female patients with a mean age of 58 years (range 8-90 years)...
April 2018: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29614542/-gastrointestinal-bleeding-update
#9
Jonel Trebicka, Martin Götz
PREENDOSCOPIC MANAGEMENT:  In suspected gastrointestinal bleeding (GIB), standard operating procedures help in risk stratification, early patient management and endoscopy. If variceal bleeding is suspected, specific medication (vasoconstrictors, antimicrobial therapy) are additive to standard pharmacological management (PPI, erythromycin) prior to endoscopy. COAGULATION REQUIRMENTS:  An emergency endoscopy can be performed independent of the patient's current coagulation status...
April 2018: Deutsche Medizinische Wochenschrift
https://www.readbyqxmd.com/read/29611507/environmental-enteropathy-in-undernourished-pakistani-children-clinical-and-histomorphometric-analyses
#10
Sana Syed, Sunil Yeruva, Jeremy Herrmann, Anne Sailer, Kamran Sadiq, Najeeha Iqbal, Furqan Kabir, Kumail Ahmed, Shahida Qureshi, Sean R Moore, Jerrold Turner, S Asad Ali
Despite nutrition interventions, stunting thought to be secondary to underlying environmental enteropathy (EE) remains pervasive among infants residing in resource-poor countries and remains poorly characterized. From a birth cohort of 380 children, 65 malnourished infants received 12 weeks of nutritional supplementation with ready-to-use therapeutic food (RUTF). Eleven children with insufficient response to RUTF underwent upper endoscopy with duodenal biopsies, which were compared with U.S., age-matched specimens for healthy, celiac disease, non-celiac villous atrophy, non-celiac intraepithelial lymphocytosis, and graft-versus-host disease patients...
April 2, 2018: American Journal of Tropical Medicine and Hygiene
https://www.readbyqxmd.com/read/29611112/sedation-practices-in-gastrointestinal-endoscopy-a-survey-from-southern-india
#11
Prakash Zacharias, Shibi Mathew, John Mathews, Aby Somu, Maya Peethambaran, Menon Prashanth, Mathew Philip
Gastrointestinal endoscopies can cause an unpleasant experience for the patient. In India, most endoscopists follow a common institutional policy for sedation. The aim of this study was to analyze the sedation practices in various endoscopy centers across southern India. Data were collected with the help of a structured questionnaire given to a senior endoscopist of the center. Data from the completed questionnaire were later analyzed. Data were obtained from 19 centers across southern India. All endoscopy suites had central oxygen supply and emergency cart...
April 3, 2018: Indian Journal of Gastroenterology: Official Journal of the Indian Society of Gastroenterology
https://www.readbyqxmd.com/read/29610558/effect-of-egualen-sodium-hydrate-on-small-intestinal-mucosal-damage-induced-by-low-dose-aspirin-a-prospective-randomized-clinical-trial
#12
Munetaka Iguchi, Kazuki Kakimoto, Takanori Kuramoto, Kei Nakazawa, Minori Kubota, Yuki Hirata, Kaori Fujiwara, Satoshi Harada, Taisuke Sakanaka, Kazuhiro Ota, Shoko Edogawa, Yuichi Kojima, Sadaharu Nouda, Toshihiko Okada, Ken Kawakami, Toshihisa Takeuchi, Takuya Inoue, Kazuhide Higuchi
Low-dose aspirin, which is widely used to reduce the risk of cardio- and cerebrovascular thrombosis, often induces gastroenteropathy by increasing the permeability of the mucosa. However, therapeutic strategies for patients with low-dose aspirin-induced small intestinal injury have not been determined. We evaluated the preventative effect of egualen sodium hydrate, a gastro-protective agent that suppresses indomethacin-induced small-intestinal damage in rats, against small-intestinal mucosal damage induced by low-dose aspirin in healthy adult male volunteers...
March 2018: Journal of Clinical Biochemistry and Nutrition
https://www.readbyqxmd.com/read/29601434/pediatric-collagenous-gastritis-and-colitis-a-case-series-and-review-of-the-literature
#13
Judy Matta, George Alex, Donald J S Cameron, Chung W Chow, Winita Hardikar, Ralf G Heine
INTRODUCTION: Collagenous gastritis is a rare disease characterized by the subepithelial deposition of collagen bands. Two phenotypes of the disease have been described: a pediatric-onset and an adult-onset type. The adult-onset form is associated with collagenous colitis and autoimmune disorders. No effective treatment has been identified to date. OBJECTIVE: We aim to describe the clinical features and outcomes of patients in our cohort and provide a summary of published pediatric cases with collagenous gastritis and colitis reported to date to gather information that will contribute to improved knowledge of this rare condition...
March 29, 2018: Journal of Pediatric Gastroenterology and Nutrition
https://www.readbyqxmd.com/read/29594977/low-prevalence-of-biopsy-proven-eosinophilic-esophagitis-in-patients-with-esophageal-food-impaction-in-mexican-population
#14
Diego García-Compeán, José A González-González, José J Duran-Castro, Gilberto Herrera-Quiñones, Omar D Borjas-Almaguer, Héctor J Maldonado-Garza
BACKGROUND: Eosinophilic esophagitis (EoE) is the most common cause of dysphagia and esophageal food impaction (EFI) in the USA, Western Europe, and Australia. In Mexico, the uncomplicated form of this disease is infrequent, and prevalence in patients with EFI is unknown. AIMS: To determine the prevalence and causes of EFI, endoscopic and therapeutic aspects, and establish the prevalence of biopsy-proven EoE in patients with EFI. METHODS: Diagnostic upper gastrointestinal endoscopy reports from January 2011 to December 2016 were retrospectively reviewed...
March 29, 2018: Digestive Diseases and Sciences
https://www.readbyqxmd.com/read/29574077/wheat-amylase-trypsin-inhibitors-exacerbate-intestinal-and-airway-allergic-immune-responses-in-humanized-mice
#15
Iris Bellinghausen, Benno Weigmann, Victor Zevallos, Joachim Maxeiner, Sonja Reißig, Ari Waisman, Detlef Schuppan, Joachim Saloga
BACKGROUND: Amylase-trypsin inhibitors (ATIs) in wheat and related cereals are potent activators of myeloid innate immune cells via engagement of TLR4. Furthermore, ATIs have been shown to serve as adjuvants in experimental intestinal inflammatory diseases. OBJECTIVE: The aim of this study was to analyze whether ATIs are also modifiers of allergic inflammation. METHODS: Therefore, CD4+ T cells from grass or birch pollen sensitized donors were stimulated with autologous allergen-pulsed dendritic cells in the presence or absence of ATIs or the control storage protein zein from corn...
March 21, 2018: Journal of Allergy and Clinical Immunology
https://www.readbyqxmd.com/read/29570557/the-use-and-safety-of-a-novel-haemostatic-spray-in-the-endoscopic-management-of-acute-non-variceal-upper-gastrointestinal-bleeding-in-children
#16
Mike Thomson, Arun Urs, Priya Narula, Prithviraj Rao, Dalia Belsha
AIMS AND BACKGROUND: Advanced endo-haemostatic technique performance and experience is extremely variable in distribution amongst pediatric endoscopists. Haemostatic spray (Hemospray®), a novel endo-haemostatic topically applied powder has the advantage of extreme ease of use and; hence may lower the threshold of competency required by the endoscopist thereby potentially reducing mortality. The aim of the study is to prospectively evaluate the efficacy and the safety of haemostatic spray in paediatric patients with AUGIB...
March 22, 2018: Journal of Pediatric Gastroenterology and Nutrition
https://www.readbyqxmd.com/read/29566478/the-usefulness-of-cap-assisted-endoscopic-retrograde-cholangiopancreatography-for-cannulation-complicated-by-a-periampullary-diverticulum
#17
Joonhwan Kim, Jun Soo Lee, Eui Joo Kim, Yeon Suk Kim, Jae Hee Cho
Endoscopic retrograde cholangiopancreatography (ERCP) is an advanced therapeutic procedure to manage choledocholithiasis and pancreatobiliary malignancy. On occasion, ERCP failure is encountered due to difficulties in cannulation. We assessed the safety and feasibility of cap-assisted ERCP via analyzing cases in which cannulation was complicated by periampullary diverticulum. Between November 2013 and March 2014, ERCP procedures were performed in 346 patients in our tertiary medical center. Among the 73 patients who had a periampullary diverticulum, conventional ERCP failed in 5 patients due to hidden papilla (n=3) or use of tangential approach (n=2)...
March 25, 2018: Korean Journal of Gastroenterology, Taehan Sohwagi Hakhoe Chi
https://www.readbyqxmd.com/read/29560646/esophageal-lesions-detected-during-small-bowel-capsule-endoscopy-incidence-diagnostic-and-therapeutic-impact
#18
J F Juanmartiñena Fernández, I Fernández-Urién Sainz, C Saldaña Dueñas, A Elosua González, M Montañés Guimera, B Zabalza Ollo, S Pardo González, J J Vila Costas
BACKGROUND: Nowadays, capsule endoscopy is the first-line procedure for the visualization of the small bowel. Although it was primarily designed with this goal, it may also identify other segments of the gastrointestinal tract. The aim of the current study is to evaluate the incidence of esophageal abnormalities detected in patients undergoing small bowel capsule endoscopy and its impact on patient management. PATIENTS AND METHODS: This study is a retrospective analysis of data from 2217 consecutive capsule endoscopy procedures performed at a single tertiary-care centre between January 2008 and February 2016...
October 2017: Acta Gastro-enterologica Belgica
https://www.readbyqxmd.com/read/29559225/a-pilot-single-center-prospective-randomized-trial-to-assess-the-short-term-effect-of-a-flashing-warning-light-on-reducing-fluoroscopy-time-and-radiation-exposure-during-ercp
#19
Hong-Ze Zeng, Qin Liu, Hong-Lin Chen, Wei Liu, Qi-Shan Zeng, Chun-Cheng Wu, Bing Hu
BACKGROUND AND AIMS: ERCP has the risk of exposure to ionizing radiation. Performers may unconsciously increase fluoroscopy time (FT) due to lack of radiation protection awareness. This study investigates whether a flashing warning light adopted as a behavioral intervention for performers reduces FT and radiation exposure during ERCP. METHODS: We conducted a prospective randomized trial of 200 therapeutic ERCPs. A flashing warning light was placed on top of the endoscopy monitor...
March 17, 2018: Gastrointestinal Endoscopy
https://www.readbyqxmd.com/read/29559142/first-detection-of-cryptosporidium-parvum-in-falcons-falconiformes-diagnosis-molecular-sequencing-therapeutic-trial-and-epidemiological-assessment-of-a-possible-emerging-disease-in-captive-falcons
#20
Panagiotis Azmanis, Antonio di Somma, Lucia Pappalardo, Christu-Das Silvanose, Berit Bangoura
Cryptosporidiosis in raptors and falcons is well-known to be caused by Cryptosporidium baileyi and associated mainly with respiratory pathology. This report presents the diagnosis of an atypical cryptosporidiosis event caused by Cryptosporidium parvum, that to the authors' knowledge, is a case observed for the first time in falcons. Two falcons (Gyrfalcon x Peregrine hybrids) were presented for annual check without any clinical signs. Hematology, biochemistry, fecal and crop parasitology, radiographic and endoscopic examinations were performed...
March 15, 2018: Veterinary Parasitology
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