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https://www.readbyqxmd.com/read/28214716/early-career-psychiatrists-preferences-on-e-learning-viewpoint-from-the-epa-committee-on-education
#1
EDITORIAL
M Casanova Dias, D Giacco, C Hanon
No abstract text is available yet for this article.
December 20, 2016: European Psychiatry: the Journal of the Association of European Psychiatrists
https://www.readbyqxmd.com/read/28214193/quantification-of-the-overall-measurement-uncertainty-associated-with-the-passive-moss-biomonitoring-technique-sample-collection-and-processing
#2
J R Aboal, M T Boquete, A Carballeira, A Casanova, S Debén, J A Fernández
In this study we examined 6080 data gathered by our research group during more than 20 years of research on the moss biomonitoring technique, in order to quantify the variability generated by different aspects of the protocol and to calculate the overall measurement uncertainty associated with the technique. The median variance of the concentrations of different pollutants measured in moss tissues attributed to the different methodological aspects was high, reaching values of 2851 (ng·g(-1))(2) for Cd (sample treatment), 35...
February 14, 2017: Environmental Pollution
https://www.readbyqxmd.com/read/28202785/behavioral-and-physiological-consequences-of-adult-brain-5-ht-depletion-in-mice
#3
José Patricio Casanova
No abstract text is available yet for this article.
February 15, 2017: Journal of Neuroscience: the Official Journal of the Society for Neuroscience
https://www.readbyqxmd.com/read/28199929/identification-of-natural-red-and-purple-dyes-on-textiles-by-fiber-optics-reflectance-spectroscopy
#4
M A Maynez-Rojas, E Casanova-González, J L Ruvalcaba-Sil
Understanding dye chemistry and dye processes is an important issue for studies of cultural heritage collections and science conservation. Fiber Optics Reflectance Spectroscopy (FORS) is a powerful technique, which allows preliminary dye identification, causing no damage or mechanical stress on the artworks subjected to analysis. Some information related to specific light scattering and absorption can be obtained in the UV-visible and infrared range (300-1400nm) and it is possible to discriminate the kind of support fiber in the near infrared region (1000-2500nm)...
February 9, 2017: Spectrochimica Acta. Part A, Molecular and Biomolecular Spectroscopy
https://www.readbyqxmd.com/read/28179368/a-common-group-of-eggshell-proteins-ensure-the-transfer-of-both-dorsoventral-and-terminal-information-from-ovary-to-embryo-in-drosophila
#5
Alessandro Mineo, Marc Furriols, Jordi Casanova
The Drosophila eggshell is an extracellular matrix that confers protection to the egg and also plays a role in transferring positional information from the ovary to pattern the embryo. Among the constituents of the Drosophila eggshell, Nasrat, Polehole and Closca form a group of proteins related by sequence, secreted by the oocyte and mutually required for their incorporation into the eggshell. Besides their role in eggshell integrity, Nasrat, Polehole and Closca are also required for embryonic terminal patterning by anchoring or stabilizing Torso-like at the eggshell...
February 7, 2017: Genetics
https://www.readbyqxmd.com/read/28177045/maxadilan-simile-expression-in-nyssomyia-neivai-a-sandfly-vector-in-an-endemic-region-of-brazil-and-its-immunogenicity-in-patients-with-american-tegumentary-leishmaniasis
#6
Juliana Aires, Claudio Casanova, Sebastian Vernal, Margarida Nascimento, Sandra Rodrigues, Ethan A Lerner, Ana Maria Roselino
BACKGROUND: Maxadilan (Max) is a salivary component in the sandfly Lutzomyia longipalpis (Lutz & Neiva 1912), a vector of visceral leishmaniasis. Max has a powerful vasodilatory effect and is a candidate vaccine that has been tested in experimental leishmaniasis. Nyssomyia neivai (Pinto 1926) is a vector of the pathogen responsible for American tegumentary leishmaniasis (ATL) in Brazil. OBJECTIVE: We searched for Max expression in Ny. neivai and for antibodies against Max in ATL patients...
February 2017: Memórias do Instituto Oswaldo Cruz
https://www.readbyqxmd.com/read/28174643/romiplostim-therapy-as-a-second-line-treatment-before-splenectomy-for-refractory-immune-thrombocytopenia-in-a-cirrhotic-patient-with-iatrogenic-cushing-syndrome-secondary-to-corticosteroids
#7
Teresa Casanovas Taltavull, Maria Carmen Peña-Cala
Our case report discusses the usefulness of administering romiplostim as a second-line treatment before splenectomy in a cirrhotic patient with immune thrombocytopenia who developed corticosteroid-induced Cushing's syndrome. Corticosteroids were tapered and consequently withdrawn. The patient made a full recovery postsplenectomy.
February 2017: Clinical Case Reports
https://www.readbyqxmd.com/read/28172454/dop016-long-term-safety-of-in-utero-exposure-to-anti-tumor-necrosis-factor-for-the-treatment-of-inflammatory-bowel-diseases-results-from-the-multicenter-european-teddy-study
#8
M Chaparro, A Verreth, T Lobaton, E Gravito-Soares, M Julsgaard, E Savarino, F Magro, I Avni Biron, P Lόpez-Serrano, M Casanova, M Gompertz, S Vitor, M Arroyo, D Pugliese, Y Zabana, R Vicente, M Aguas, A Bar-Gil Shitrit, A Gutierrez, G Doherty, L Fernández-Salazar, J Martinez Cadilla, J Huguet, A O'Toole, E Stasi, N Manceñido Marcos, A Villoria, K Karmiris, J Rahier, C Rodriguez, M Diz-Lois Palomares, G Fiorino, J Benítez, M Principi, T Naftali, C Taxonera, G Mantzaris, L Sebkova, B Iade, D Lissner, I Ferrer Bradley, A Lόpez-San Román, I Marín-Jiménez, O Merino, M Sierra, M Van Domselaar, F Caprioli, I Guerra, P Peixe, M Piqueras, I Rodríguez-Lago, Y Ber, K Van Hoeve, P Torres, E Gravito-Soares, D Rudbeck-Thomsen, O Bartolo, A Peixoto, G Martín, J Pérez, A Garre, M G Donday, J Martín de Carpi, J P Gisbert
No abstract text is available yet for this article.
February 1, 2017: Journal of Crohn's & Colitis
https://www.readbyqxmd.com/read/28167373/extraskeletal-osteosarcoma-a-european-musculoskeletal-oncology-society-study-on-266-patients
#9
A Longhi, S S Bielack, R Grimer, J Whelan, R Windhager, A Leithner, A Gronchi, D Biau, P Jutte, A H Krieg, F M Klenke, G Grignani, D M Donati, R Capanna, J Casanova, C Gerrand, G Bisogno, S Hecker-Nolting, M De Lisa, L D'Ambrosio, M Willegger, G Scoccianti, S Ferrari
PURPOSE: Prognosis of extraskeletal osteosarcoma (ESOS) is reported to be poorer than that of skeletal osteosarcoma. This multicenter retrospective study aimed to evaluate factors influencing ESOS prognosis. PATIENTS AND METHODS: Members of the European Musculoskeletal Oncology Society (EMSOS) submitted institutional data on patients with ESOS. RESULTS: Data from 274 patients treated from 1981 to 2014 were collected from 16 EMSOS centres; 266 patients were eligible...
February 3, 2017: European Journal of Cancer
https://www.readbyqxmd.com/read/28155026/early-experience-with-compassionate-use-of-2-hydroxypropyl-beta-cyclodextrin-for-niemann-pick-type-c-disease-review-of-initial-published-cases
#10
REVIEW
Juan Eduardo Megías-Vericat, Ana García-Robles, María José Company-Albir, María José Fernández-Megía, Francisco Carlos Pérez-Miralles, Eduardo López-Briz, Bonaventura Casanova, José Luis Poveda
Niemann-Pick type C (NP-C) is a rare neurodegenerative disorder. Management is mainly supportive and symptomatic. The investigational use of 2-hydroxypropyl-β-cyclodextrin (HP-β-CD) showed a promising role in treating NP-C, although efficacy and safety have not been established. We conducted searches of MEDLINE, Cochrane, EMBASE, and other databases of reported cases of HP-β-CD compassionate use in NP-C disease. Sixteen reported cases were eligible, including evaluable information of 17 patients. The median onset age of HP-β-CD was 14 years (range 2-49 years)...
February 2, 2017: Neurological Sciences
https://www.readbyqxmd.com/read/28154164/sex-differences-in-the-association-between-insulin-resistance-and-incident-coronary-heart-disease-and-stroke-among-blacks-without-diabetes-mellitus-the-jackson-heart-study
#11
Valery S Effoe, Lynne E Wagenknecht, Justin B Echouffo Tcheugui, Haiying Chen, Joshua J Joseph, Rita R Kalyani, Ronny A Bell, Wen-Chih H Wu, Ramon Casanova, Alain G Bertoni
BACKGROUND: Studies exploring the association between insulin resistance (IR) and cardiovascular disease in blacks have not been conclusive, especially for coronary heart disease (CHD). The McAuley index and homeostasis model assessment of IR (HOMA-IR) perform differently in predicting cardiovascular disease. We investigated this association in the Jackson Heart Study, a large longitudinal cohort of blacks. METHODS AND RESULTS: IR was estimated for 3565 participants without diabetes mellitus and cardiovascular disease at baseline using the McAuley index and HOMA-IR, and their associations with incident CHD and stroke (composite outcome) were compared...
February 2, 2017: Journal of the American Heart Association
https://www.readbyqxmd.com/read/28140494/the-impact-of-water-management-practices-on-subtropical-pasture-methane-emissions-and-ecosystem-service-payments
#12
Samuel D Chamberlain, Peter M Groffman, Elizabeth H Boughton, N Gomez-Casanovas, Evan H DeLucia, Carl J Bernacchi, Jed P Sparks
Pastures are an extensive land cover type; however, patterns in pasture greenhouse gas (GHG) exchange vary widely depending on climate and land management. Understanding this variation is important, as pastures may be a net GHG source or sink depending on these factors. We quantified carbon dioxide (CO2 ) and methane (CH4 ) fluxes from subtropical pastures in south Florida for three wet-dry seasonal cycles using eddy covariance, and estimated two annual budgets of CO2 , CH4 , and GHG equivalent emissions. We also estimated the impact of water retention practices on pasture GHG emissions and assessed the impact of these emissions on stakeholder payments for water retention services in a carbon market framework...
January 31, 2017: Ecological Applications: a Publication of the Ecological Society of America
https://www.readbyqxmd.com/read/28139061/immunohistochemical-and-molecular-profile-of-salivary-gland-cancer-in-children
#13
Laura D Locati, Paola Collini, Martina Imbimbo, Marta Barisella, Adele Testi, Lisa F Licitra, Thomas Löning, Katharina Tiemann, Pasquale Quattrone, Emanuela Bimbatti, Stefano Chiaravalli, Michela Casanova, Elena Tamborini, Roberto Carta, Patrizia Gasparini, Marco Guzzo, Maura Massimino, Andrea Ferrari
BACKGROUND: Pediatric salivary gland carcinomas (SGCs) are very rare. They differ from the adult SGCs in terms of epidemiologic and clinical behavior, being generally limited only to selected histotypes (e.g. low-grade mucoepidermoid [LG-MEC] and acinic cell cancer [AcCC]) and characterized by very good outcome. Our aim was to investigate therapeutic targets on a series of pediatric SGCs by immunohistochemical and molecular analysis. METHODS: A retrospective analysis was performed to search for cases of pediatric SGCs in the database of the Pediatric Oncology Unit at the Istituto Nazionale Tumori and in the Pathology database at the Gerhard-Seifert-Reference-Centre...
January 31, 2017: Pediatric Blood & Cancer
https://www.readbyqxmd.com/read/28125783/donor-acceptor-interaction-determines-the-mechanism-of-photoinduced-electron-injection-from-graphene-quantum-dots-into-tio2-%C3%AF-stacking-supersedes-covalent-bonding
#14
Run Long, David Casanova, Wei-Hai Fang, Oleg V Prezhdo
Interfacial electron transfer (ET) constitutes the key step in conversion of solar energy into electricity and fuels. Required for fast and efficient charge separation, strong donor-acceptor interaction is typically achieved through covalent chemical bonding and leads to fast, adiabatic ET. Focusing on interfaces of pyrene, coronene, and a graphene quantum dot (GQD) with TiO2, we demonstrate the opposite situation: covalent bonding leads to weak coupling and nonadiabatic (NA) ET, while through-space π-electron interaction produces adiabatic ET...
February 9, 2017: Journal of the American Chemical Society
https://www.readbyqxmd.com/read/28117095/preconditioning-by-portal-vein-embolization-modulates-hepatic-hemodynamics-and-improves-liver-function-in-pigs-with-extended-hepatectomy
#15
José M Asencio, José L García-Sabrido, José A López-Baena, Luis Olmedilla, Isabel Peligros, Pablo Lozano, Álvaro Morales-Taboada, Carolina Fernández-Mena, Miguel A Steiner, Emma Sola, José M Perez-Peña, Miriam Herrero, Juan Laso, Cristina Lisbona, Rafael Bañares, Javier Casanova, Javier Vaquero
BACKGROUND: Portal vein embolization is performed weeks before extended hepatic resections to increase the future liver remnant and prevent posthepatectomy liver failure. Portal vein embolization performed closer to the operation also could be protective, but worsening of portal hyper-perfusion is a major concern. We determined the hepatic hemodynamic effects of a portal vein embolization performed 24 hours prior to hepatic operation. METHODS: An extended (90%) hepatectomy was performed in swine undergoing (portal vein embolization) or not undergoing (control) a portal vein embolization 24 hours earlier (n = 10/group)...
January 20, 2017: Surgery
https://www.readbyqxmd.com/read/28108518/a-transposon-based-analysis-reveals-rasa1-is-involved-in-triple-negative-breast-cancer
#16
Cristian Suárez-Cabrera, Rita M Quintana, Ana Bravo, M LLanos Casanova, Angustias Page, Josefa P Alameda, Jesus M Paramio, Alicia Maroto, Javier Salamanca, Adam J Dupuy, Angel Ramírez, Manuel Navarro
RAS genes are mutated in 20% of human tumors, but these mutations are very rare in breast cancer. Here we used a mouse model to generate tumors upon activation of a mutagenic T2Onc2 transposon via expression of a transposase driven by the keratin K5 promoter in a p53+/- background. These animals mainly developed mammary tumors, most of which had transposon insertions in one of two RASGAP genes, neurofibromin1 (NF1) and RAS p21 protein activator (Rasa1). Immunohistochemical analysis of a collection of human breast tumors confirmed that low expression of RASA1 is frequent in basal (triple-negative) and ER-negative tumors...
January 20, 2017: Cancer Research
https://www.readbyqxmd.com/read/28107176/integrating-neurobiology-of-emotion-regulation-and-trauma-therapy-reflections-on-emdr-therapy
#17
Anabel González, Lucía Del Río-Casanova, Ania Justo-Alonso
Emotion dysregulation is a frequent feature in trauma-related disorders. Different kinds of emotion dysregulation seem to be linked to particular psychiatric conditions, and there is growing evidence of the association between neurobiological correlates and those dysregulation patterns. Nevertheless, many of the recent findings from the field of the neurobiology have not been translated into clinical practice and are insufficiently contemplated in trauma-oriented therapies. The aim of this article is to review recent developments in the field of emotion regulation connecting these issues with the practical implementation of psychotherapeutic procedures...
January 20, 2017: Reviews in the Neurosciences
https://www.readbyqxmd.com/read/28106484/equipping-doctors-for-global-health-challenges
#18
Marisa Casanova Dias, Aula Abbara, Rosie Gilbert, May Ci van Schalkwyk, Claire P Rees, Howard Ryland, Andrew Jm Leather, Bhanu Williams, Nigel Crisp
No abstract text is available yet for this article.
January 2017: Journal of the Royal Society of Medicine
https://www.readbyqxmd.com/read/28104379/a-thoracic-parasternal-granular-cell-tumor-in-a-child-about-one-case-and-review-of-the-literature-discussion-about-treatment-guidelines-is-complete-resection-compulsory
#19
C Jaloux, N Degardin, M Cegarra-Escolano, M C Habib, C Philandrianos, D Casanova
Granular cell tumor is a well known soft tissue tumor, very rare in children; we describe here the first case of GCT in this particular location in a child. The diagnostic is easily done with histopathology. The treatment is based on the complete resection, no other validated treatment exists. We reviewed the literature to find out if it would be safe to consider a simple follow-up after partial resection of the tumor.
January 16, 2017: Annales de Chirurgie Plastique et Esthétique
https://www.readbyqxmd.com/read/28102622/successful-surgical-management-of-congenital-kasabach-merritt-syndrome
#20
Sébastien Pascal, Quentin Bettex, Nicolas Andre, Philippe Petit, Dominique Casanova, Nathalie Degardin
Since the first description of Kasabach-Merritt syndrome (KMS) in 1940, many treatments have been proposed combining pharmacologic and non-pharmacologic approaches, which can be effective on the pathology but can have adverse and unpredictable side-effects with long-term use. Herein we describe the solely surgical treatment of Kasabach-Merritt syndrome in a neonate with a severe and rapidly progressive thrombocytopenia. The patient's condition normalized at 7 days postoperatively, with rapid increase in platelet count and normalization of d-dimer concentration...
January 2017: Pediatrics International: Official Journal of the Japan Pediatric Society
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